{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:45:04Z","timestamp":1772120704999,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiac resynchronisation therapy (CRT) is a validated treatment for heart failure (HF) patients in NYHA class III\u2013IV despite optimal medical therapy. We aimed to assess the beneficial effects of CRT in patients with catecholamine-dependent overt HF (CDOHF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied 20 CDOHF patients who had undergone CRT implantation. Patients had a mean baseline QRS duration of 174\u201325 ms and\/or echocardiographic asynchrony, and LVEF of 18\u20133%. Mean follow-up was 18\u201312 months. Dependence on catecholamine agents was defined as the inability to stop or reduce drug infusion without re-occurrence of hypotension, low urine output and hypoxaemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After CRT implantation, catecholamine agents were mostly withdrawn within 2days and blood pressure, urine output and BNP rapidly improved within 24h. During follow-up, survival rates were 85% at 3months, 80% at 6months and 55% at 18 months. Among the 9 deaths, 5 were related to overt HF, 3 to sudden cardiac death and 1 to non-cardiac death. LVEF improved from 18\u00b13% to 21\u00b14% three months after CRT implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\u201cRescue\u201d CRT implantation in CDOHF patients allowed a rapid and successful catecholamine weaning in all studied patients. Furthermore, this immediate beneficial effect is sustained for more than one year in surviving patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ejheart.2008.02.006","type":"journal-article","created":{"date-parts":[[2008,3,3]],"date-time":"2008-03-03T15:09:32Z","timestamp":1204556972000},"page":"291-297","source":"Crossref","is-referenced-by-count":21,"title":["Cardiac Resynchronisation as a Rescue Therapy in Patients with Catecholamine-Dependent Overt Heart Failure: Results from a Short and Mid-Term Study"],"prefix":"10.1093","volume":"10","author":[{"given":"Paul","family":"Milliez","sequence":"first","affiliation":[{"name":"AP-HP, Department of Cardiology, Lariboisiere Hospital, Denis Diderot University , Paris ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ambroise Pare Clinic , Neuilly sur Seine ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdeddayem","family":"Haggui","sequence":"additional","affiliation":[{"name":"AP-HP, Department of Cardiology, Lariboisiere Hospital, Denis Diderot University , Paris ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Schurando","sequence":"additional","affiliation":[{"name":"AP-HP, Department of Anesthesiology, Lariboisiere Hospital, Denis Diderot University , Paris ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Squara","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ambroise Pare Clinic , Neuilly sur Seine ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Cohen-Solal","sequence":"additional","affiliation":[{"name":"AP-HP, Department of Cardiology, Lariboisiere Hospital, Denis Diderot University , Paris 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