{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:58:29Z","timestamp":1790211509126,"version":"4.1.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Approximately one third of patients with chronic heart failure have left bundle branch block (LBBB) on their 12-lead ECG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>1418 consecutive patients (average (SD) age 70.5 (10.4) years; 74% male) first seen in a community heart failure clinic between December 2001 and June 2006 had a 12 lead electrocardiogram (ECG). 485 (34%) had a QRS duration \u2265 120ms. Patients with a broad QRS were older (72.2 v 69.3years), had worse left ventricular systolic function, were on a higher daily dose of diuretic and were more likely to be on amiodarone (14.4 v 7.1%).<\/jats:p>\n                    <jats:p>12 lead ECG was available for 734 patients (52%) at 1year follow up. The QRS interval increased from 115.1ms at baseline to 117.6 (P&amp;lt;0.0001). There were 52 incident cases of LBBB, an incidence of 10.9%. The only predictors of incident LBBB were QRS duration at baseline and amiodarone use at baseline. The proportion of patients with LBBB increased from 34.0% at baseline to 36.7%, 37.7% and 42.3% at 1, 2 and 3 years follow up, respectively. Baseline LBBB was associated with a worse outcome (HR 1.25 (95% CI 1.01\u20131.55). New LBBB was an independent adverse prognostic feature (HR 2.09 (95% CI 1.17\u20133.73); P=0.013).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The crude incidence of LBBB is 10.9% in the first year of follow up in an unselected population of ambulatory outpatients with chronic stable heart failure. Ongoing care of patients with chronic heart failure should include a regular 12 lead electrocardiogram.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ejheart.2008.05.001","type":"journal-article","created":{"date-parts":[[2008,5,24]],"date-time":"2008-05-24T06:17:54Z","timestamp":1211609874000},"page":"696-702","source":"Crossref","is-referenced-by-count":57,"title":["The Prevalence and Incidence of Left Bundle Branch Block in Ambulant Patients with Chronic Heart Failure"],"prefix":"10.1093","volume":"10","author":[{"given":"Andrew L.","family":"Clark","sequence":"first","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Castle Road, Cottingham, Hull, UK. HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Goode","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Castle Road, Cottingham, Hull, UK. HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.F.","family":"Cleland","sequence":"additional","affiliation":[{"name":"Department of Academic Cardiology, Castle Hill Hospital , Castle Road, Cottingham, Hull, UK. HU16 5JQ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"2026020203421668900_ejhf2008-05-001-bib-0001","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1378\/chest.122.2.528","article-title":"Congestive heart failure and QRS duration: establishing prognosis study","volume":"122","author":"Shenkman","year":"2002","journal-title":"Chest"},{"key":"2026020203421668900_ejhf2008-05-001-bib-0002","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1067\/mhj.2002.121264","article-title":"Italian Network on Congestive Heart Failure Investigators. 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