{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:08:09Z","timestamp":1783487289434,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.ejim.2011.06.016","type":"journal-article","created":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T17:08:24Z","timestamp":1312477704000},"page":"192-195","source":"Crossref","is-referenced-by-count":34,"title":["An observational study on bloodstream extended-spectrum beta-lactamase infection in critical care unit: Incidence, risk factors and its impact on outcome"],"prefix":"10.1016","volume":"23","author":[{"given":"Prashant","family":"Nasa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deven","family":"Juneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omender","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Dang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhilesh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejim.2011.06.016_bb0005","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.amjmed.2006.03.013","article-title":"Resistance in gram-negative bacteria: Enterobacteriaceae","volume":"119","author":"Paterson","year":"2006","journal-title":"Am J Med"},{"key":"10.1016\/j.ejim.2011.06.016_bb0010","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1086\/420816","article-title":"Antibiotic therapy for Klebsiella pneumonia bacteremia: implications of production of extended-spectrum betalactamases","volume":"39","author":"Paterson","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0015","doi-asserted-by":"crossref","first-page":"S164","DOI":"10.1086\/500663","article-title":"Extended-spectrum beta-lactamases and clinical outcomes: current data","volume":"42","author":"Ramphal","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0020","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1592\/phco.21.11.920.34529","article-title":"ESBLs: epidemiology, detection and treatment","volume":"21","author":"Nathisuwan","year":"2001","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.ejim.2011.06.016_bb0025","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1128\/AAC.00426-09","article-title":"Emergence of high levels of extended-spectrum-\u03b2-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007","volume":"53","author":"Hawser","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ejim.2011.06.016_bb0030","doi-asserted-by":"crossref","first-page":"S120","DOI":"10.1592\/phco.19.12.120S.31699","article-title":"Successful interventions for gram-negative resistance to extended-spectrum \u03b2-lactam antibiotics","volume":"19","author":"Rice","year":"1999","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.ejim.2011.06.016_bb0035","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.diagmicrobio.2005.04.004","article-title":"Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998\u20132002)","volume":"52","author":"Hirakata","year":"2005","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0040","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.diagmicrobio.2006.08.016","article-title":"Comparative activities of cefepime and piperacillin\/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype","volume":"57","author":"Sader","year":"2007","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0045","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4103\/0377-4929.54988","article-title":"Ventilator-associated pneumonia caused by carbapenem-resistant Enterobacteriaceae carrying multiple metallo-beta-lactamase genes","volume":"52","author":"Dwivedi","year":"2009","journal-title":"Indian J Pathol Microbiol"},{"key":"10.1016\/j.ejim.2011.06.016_bb0050","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1473-3099(10)70143-2","article-title":"Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study","volume":"10","author":"Kumarasamy","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0055","first-page":"147","article-title":"New Delhi metallo-b lactamase (NDM-1) in Enterobacteriaceae: treatment options with carbapenems compromised","volume":"58","author":"Deshpande","year":"2010","journal-title":"J Assoc Physicians India"},{"key":"10.1016\/j.ejim.2011.06.016_bb0060","series-title":"Performance standards for antimicrobial susceptibility testing: eighteenth informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2008"},{"key":"10.1016\/j.ejim.2011.06.016_bb0065","first-page":"417","article-title":"An update on newer beta-lactamases","volume":"126","author":"Gupta","year":"2007","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.ejim.2011.06.016_bb0070","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.3201\/eid1308.070071","article-title":"Risk factors for colonization with extended-spectrum beta-lactamase-producing bacteria and intensive care unit admission","volume":"13","author":"Harris","year":"2007","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0075","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1155\/2009\/725872","article-title":"Risk factors for and outcomes associated with clinical isolates of Escherichia coli and Klebsiella species resistant to extended-spectrum cephalosporins among patients admitted to Canadian hospitals","volume":"20","author":"Ofner-Agostini","year":"2009","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"10.1016\/j.ejim.2011.06.016_bb0080","doi-asserted-by":"crossref","first-page":"3244","DOI":"10.1128\/AAC.00063-08","article-title":"Bloodstream infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli: risk factors for inadequate initial antimicrobial therapy","volume":"52","author":"Tumbarello","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ejim.2011.06.016_bb0085","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/jac\/dkm318","article-title":"Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis","volume":"60","author":"Schwaber","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ejim.2011.06.016_bb0090","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jhin.2009.02.021","article-title":"Extended-spectrum beta-lactamase-producing organisms","volume":"73","author":"Falagas","year":"2009","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.ejim.2011.06.016_bb0095","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1586\/14787210.6.5.671","article-title":"Clinical significance of extended-spectrum beta-lactamases","volume":"6","author":"Rodr\u00edguez-Ba\u00f1o","year":"2008","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.ejim.2011.06.016_bb0100","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/infdis\/174.3.529","article-title":"Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: a case\u2013control and molecular epidemiologic investigation","volume":"174","author":"Schiappa","year":"1996","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0105","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1053\/jhin.2002.1288","article-title":"Clinical implications of extended-spectrum beta-lactamase-producing Klebsiella pneumonia bacteraemia","volume":"52","author":"Kim","year":"2002","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.ejim.2011.06.016_bb0110","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1007\/s00134-002-1521-1","article-title":"Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: risk factors and clinical outcome","volume":"28","author":"Du","year":"2002","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.ejim.2011.06.016_bb0115","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1086\/324742","article-title":"Molecular correlation for the treatment outcomes in bloodstream infections caused by Escherichia coli and Klebsiella pneumoniae with reduced susceptibility to ceftazidime","volume":"34","author":"Wong-Beringer","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ejim.2011.06.016_bb0120","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1128\/JCM.39.6.2206-2212.2001","article-title":"Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum b-lactamases: implications for the clinical microbiology laboratory","volume":"39","author":"Paterson","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ejim.2011.06.016_bb0125","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1128\/CMR.18.2.306-325.2005","article-title":"Metallo-betalactamases: the quiet before the storm?","volume":"18","author":"Walsh","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ejim.2011.06.016_bb0130","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: the versatile betalactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.ejim.2011.06.016_bb0135","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1128\/JCM.39.12.4433-4439.2001","article-title":"Outbreak of infection with multidrug-resistant Klebsiella pneumoniae carrying bla(IMP-8) in a university medical center in Taiwan","volume":"39","author":"Yan","year":"2001","journal-title":"J Clin Microbiol"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620511001403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620511001403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T15:49:45Z","timestamp":1560440985000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620511001403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0953620511001403"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2011.06.016","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}