{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T07:17:09Z","timestamp":1789802229519,"version":"4.0.1"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["1315883"],"award-info":[{"award-number":["1315883"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","ejinme.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ejim.2016.09.006","type":"journal-article","created":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T03:33:05Z","timestamp":1476675185000},"page":"e37-e39","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Effects of granulocyte-colony stimulating factor (G-CSF) on stem cell mobilization in patients with liver failure"],"prefix":"10.1016","volume":"36","author":[{"given":"Cornelius","family":"Engelmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Splith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Schmelzle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejim.2016.09.006_bb0005","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1053\/j.gastro.2013.02.042","article-title":"Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis","volume":"144","author":"Moreau","year":"2013","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.ejim.2016.09.006_bb0010","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0016-5085(89)90081-4","article-title":"Early indicators of prognosis in fulminant hepatic failure","volume":"97","author":"O'Grady","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ejim.2016.09.006_bb0015","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1053\/j.gastro.2011.11.027","article-title":"Granulocyte colony-stimulating factor mobilizes CD34+ cells and improves survival of patients with acute-on-chronic liver failure","volume":"142","author":"Garg","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ejim.2016.09.006_bb0020","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.3748\/wjg.v19.i7.1104","article-title":"Granulocyte-colony stimulating factor therapy improves survival in patients with hepatitis B virus-associated acute-on-chronic liver failure","volume":"19","author":"Duan","year":"2013","journal-title":"World J Gastroenterol"},{"issue":"9","key":"10.1016\/j.ejim.2016.09.006_bb0025","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1038\/ajg.2014.154","article-title":"Granulocyte colony-stimulating factor in severe alcoholic hepatitis: a randomized pilot study","volume":"109","author":"Singh","year":"2014","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.ejim.2016.09.006_bb0030","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0140-6736(89)90711-3","article-title":"Granulocyte-macrophage colony-stimulating factor to harvest circulating haemopoietic stem cells for autotransplantation","volume":"2","author":"Gianni","year":"1989","journal-title":"Lancet"},{"key":"10.1016\/j.ejim.2016.09.006_bb0035","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1016\/j.jhep.2014.11.045","article-title":"Acute-on-chronic liver failure: a new syndrome that will re-classify cirrhosis","volume":"62","author":"Arroyo","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.ejim.2016.09.006_bb0040","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2015.327","article-title":"Mesenchymal stem cells and immunomodulation: current status and future prospects","author":"Gao","year":"2016","journal-title":"Cell Death Dis"},{"issue":"4","key":"10.1016\/j.ejim.2016.09.006_bb0045","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/liv.12415","article-title":"Altered frequencies of dendritic cells and IFN-gamma-secreting T cells with granulocyte colony-stimulating factor (G-CSF) therapy in acute-on-chronic liver failure","volume":"34","author":"Khanam","year":"2014","journal-title":"Liver Int"},{"key":"10.1016\/j.ejim.2016.09.006_bb0050","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/SLA.0b013e31826c3ec2","article-title":"CD39 modulates hematopoietic stem cell recruitment and promotes liver regeneration in mice and humans after partial hepatectomy","volume":"257","author":"Schmelzle","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejim.2016.09.006_bb0055","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/SLA.0b013e31823d7d08","article-title":"Infusion of CD133+ bone marrow-derived stem cells after selective portal vein embolization enhances functional hepatic reserves after extended right hepatectomy: a retrospective single-center study","volume":"255","author":"Schulte Am Esch","year":"2012","journal-title":"Ann Surg"},{"key":"10.1016\/j.ejim.2016.09.006_bb0060","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1111\/j.1538-7836.2010.03900.x","article-title":"Granulocyte colony-stimulating factor (G-CSF) depresses angiogenesis in vivo and in vitro: implications for sourcing cells for vascular regeneration therapy","volume":"8","author":"Tura","year":"2010","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.ejim.2016.09.006_bb0065","doi-asserted-by":"crossref","first-page":"S263","DOI":"10.1016\/S0168-8278(15)30303-2","article-title":"CD34 patterns in bone marrow indicate the status of functional reserve of bone marrow in cirrhosis","volume":"62","author":"Bihari","year":"2015","journal-title":"J Hepatol"},{"issue":"10","key":"10.1016\/j.ejim.2016.09.006_bb0070","doi-asserted-by":"crossref","first-page":"20887","DOI":"10.3390\/ijms141020877","article-title":"Serial changes of serum growth factor levels and liver regeneration after partial hepatectomy in healthy humans","volume":"14","author":"Matsumoto","year":"2013","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ejim.2016.09.006_bb0075","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/1479-5876-10-193","article-title":"Phenotypes and clinical significance of circulating CD4+CD25+ regulatory T cells (Tregs) in patients with acute-on-chronic liver failure (ACLF)","volume":"10","author":"Yang","year":"2012","journal-title":"J Transl Med"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620516303077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620516303077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T15:25:58Z","timestamp":1656948358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620516303077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":15,"alternative-id":["S0953620516303077"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2016.09.006","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of granulocyte-colony stimulating factor (G-CSF) on stem cell mobilization in patients with liver failure","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2016.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}