{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T10:14:36Z","timestamp":1760609676241,"version":"build-2065373602"},"reference-count":9,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejinme.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.ejim.2020.04.007","type":"journal-article","created":{"date-parts":[[2020,4,16]],"date-time":"2020-04-16T18:01:19Z","timestamp":1587060079000},"page":"149-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Comparison of stroke recurrence between antiplatelet and closure therapy in cryptogenic stroke patients with patent foramen ovale and its influencing factors"],"prefix":"10.1016","volume":"78","author":[{"given":"Chuanjing","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangrong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hangyuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9247-1624","authenticated-orcid":false,"given":"Jufang","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ejim.2020.04.007_bib0001","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1056\/NEJMra1201534","article-title":"Measuring the global burden of disease[J]","volume":"369","author":"Murray","year":"2013","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.ejim.2020.04.007_bib0002","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S1474-4422(13)70310-7","article-title":"Embolic strokes of undetermined source: the case for a new clinical construct[J]","volume":"13","author":"Hart","year":"2014","journal-title":"Lancet Neurol"},{"issue":"9","key":"10.1016\/j.ejim.2020.04.007_bib0003","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1016\/j.jacc.2005.08.038","article-title":"Patent foramen ovale: current pathology, pathophysiology, and clinical status[J]","volume":"46","author":"Hara","year":"2005","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"10.1016\/j.ejim.2020.04.007_bib0004","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJMoa1705915","article-title":"Patent foramen ovale closure or anticoagulation vs. antiplatelets after stroke[J]","volume":"377","author":"Mas","year":"2017","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.ejim.2020.04.007_bib0005","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJMoa1610057","article-title":"Long-Term outcomes of patent foramen ovale closure or medical therapy after stroke[j]","volume":"377","author":"Saver","year":"2017","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.ejim.2020.04.007_bib0006","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJMoa1707404","article-title":"Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke[j]","volume":"377","author":"S\u00f8ndergaard","year":"2017","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.ejim.2020.04.007_bib0007","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/1745-6215-12-185","article-title":"The risk of paradoxical embolism (RoPE) study: developing risk models for application to ongoing randomized trials of percutaneous patent foramen ovale closure for cryptogenic stroke[J]","volume":"12","author":"Kent","year":"2011","journal-title":"Trials"},{"issue":"16","key":"10.1016\/j.ejim.2020.04.007_bib0008","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1001\/jama.288.16.2015","article-title":"Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis[j]","volume":"288","author":"Collaboration","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.ejim.2020.04.007_bib0009","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.atherosclerosis.2016.10.023","article-title":"Relation of serum homocysteine levels to cerebral artery calcification and atherosclerosis[J]","volume":"254","author":"Kim","year":"2016","journal-title":"Atherosclerosis"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620520301230?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620520301230?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:31:41Z","timestamp":1760607101000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620520301230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":9,"alternative-id":["S0953620520301230"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2020.04.007","relation":{},"ISSN":["0953-6205"],"issn-type":[{"type":"print","value":"0953-6205"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of stroke recurrence between antiplatelet and closure therapy in cryptogenic stroke patients with patent foramen ovale and its influencing factors","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2020.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}