{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:32:29Z","timestamp":1792481549863,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejinme.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.ejim.2020.04.024","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T08:04:37Z","timestamp":1587456277000},"page":"59-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Clinical phenotypes and prediction of chronicity in sarcoidosis using cluster analysis in a prospective cohort of 694 patients"],"prefix":"10.1016","volume":"77","author":[{"given":"Manuel","family":"Rubio-Rivas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9889-0272","authenticated-orcid":false,"given":"Xavier","family":"Corbella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejim.2020.04.024_bib0001","first-page":"178","article-title":"Clinical findings in 715 patients with newly detected pulmonary sarcoidosis \u2013 results of a cooperative study in former West Germany and Switzerland. WATL Study Group","volume":"15","author":"Loddenkemper","year":"1998","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0002","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1164\/ajrccm.164.10.2104046","article-title":"Clinical characteristics of patients in a case control study of sarcoidosis","volume":"164","author":"Baughman","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ejim.2020.04.024_bib0003","first-page":"119","article-title":"The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States","volume":"29","author":"Judson","year":"2012","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0004","doi-asserted-by":"crossref","unstructured":"Haldar P, Berair R. Endotypes and asthma. In: Bernstein JS, Levy M, editors. Clinical asthma. Theory and practice. Boca Raton: CRC Press. 2014: 39-43.","DOI":"10.1201\/b16468-4"},{"key":"10.1016\/j.ejim.2020.04.024_bib0005","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.0954-6820.1952.tb13864.x","article-title":"The Bilateral Hilar Lymphoma Syndrome. A study of the relation to age and sex in 212 cases","volume":"142","author":"L\u00f6fgren","year":"1952","journal-title":"Acta Med Scand"},{"key":"10.1016\/j.ejim.2020.04.024_bib0006","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.0954-6820.1952.tb13865.x","article-title":"The Bilateral Hilar Lymphoma Syndrome. A study of the relation to tuberculosis and sarcoidosis in 212 cases","volume":"142","author":"L\u00f6fgren","year":"1952","journal-title":"Acta Med Scand"},{"key":"10.1016\/j.ejim.2020.04.024_bib0007","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/j.0954-6820.1953.tb07039.x","article-title":"Primary pulmonary sarcoidosis. I. Early signs and symptoms","volume":"145","author":"L\u00f6fgren","year":"1953","journal-title":"Acta Med Scand"},{"key":"10.1016\/j.ejim.2020.04.024_bib0008","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.0954-6820.1953.tb07044.x","article-title":"Primary pulmonary sarcoidosis. II. Clinical course and prognosis","volume":"145","author":"L\u00f6fgren","year":"1953","journal-title":"Acta Med Scand"},{"key":"10.1016\/j.ejim.2020.04.024_bib0009","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1164\/rccm.200608-1197OC","article-title":"Sex-specific manifestations of L\u00f6fgren's syndrome","volume":"175","author":"Grunewald","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ejim.2020.04.024_bib0010","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1586\/eci.11.76","article-title":"HLA associations and L\u00f6fgren's syndrome","volume":"8","author":"Grunewald","year":"2012","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.ejim.2020.04.024_bib0011","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/MCP.0000000000000077","article-title":"Clinical phenotypes in sarcoidosis","volume":"20","author":"Pereira","year":"2014","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.ejim.2020.04.024_bib0012","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1093\/hmg\/ddq325","article-title":"Sarcoidosis HLA class II genotyping distinguishes differences of clinical phenotype across ethnic groups","volume":"19","author":"Sato","year":"2010","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ejim.2020.04.024_bib0013","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1378\/chest.129.5.1234","article-title":"A new tool to assess sarcoidosis severity","volume":"129","author":"Wasfi","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.ejim.2020.04.024_bib0014","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1164\/rccm.200705-742OC","article-title":"Phenotyping sarcoidosis from a pulmonary perspective","volume":"177","author":"Prasse","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ejim.2020.04.024_bib0015","first-page":"56","article-title":"Defining the clinical outcome status (COS) in sarcoidosis: results of WASOG Task Force","volume":"28","author":"Baughman","year":"2011","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0016","first-page":"34","article-title":"Factor analysis of sarcoidosis phenotypes at two referral centers in Brazil","volume":"28","author":"Rodrigues","year":"2011","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0017","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S2213-2600(13)70276-5","article-title":"An integrated clinicoradiological staging system for pulmonary sarcoidosis: a case-cohort study","volume":"2","author":"Walsh","year":"2014","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.ejim.2020.04.024_bib0018","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00991-2017","article-title":"Phenotypes of organ involvement in sarcoidosis","volume":"51","author":"Schupp","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ejim.2020.04.024_bib0019","doi-asserted-by":"crossref","first-page":"43965","DOI":"10.1038\/srep43965","article-title":"Cluster analysis: a new approach for identification of underlying risk factors for coronary artery disease in essential hypertensive patients","volume":"7","author":"Guo","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejim.2020.04.024_bib0020","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1016\/j.jaip.2019.02.011","article-title":"Novel Trajectories for Identifying Asthma Phenotypes: A Longitudinal Study in Korean Asthma Cohort, COREA","volume":"7","author":"Park","year":"2019","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.1016\/j.ejim.2020.04.024_bib0021","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.chest.2017.09.026","article-title":"Phenotypic Clusters Predict Outcomes in a Longitudinal Interstitial Lung Disease Cohort","volume":"153","author":"Adegunsoye","year":"2018","journal-title":"Chest"},{"key":"10.1016\/j.ejim.2020.04.024_bib0022","doi-asserted-by":"crossref","first-page":"e7595","DOI":"10.1097\/MD.0000000000007595","article-title":"Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona","volume":"96","author":"Ma\u00f1\u00e1","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ejim.2020.04.024_bib0023","first-page":"149","article-title":"ATS\/ERS\/WASOG Statement on sarcoidosis","volume":"16","author":"Hunninghake","year":"1999","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0024","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1136\/bmj.2.5261.1165","article-title":"Prognosis of intrathoracic sarcoidosis in England. A review of 136 cases after five years' observation","volume":"2","author":"Scadding","year":"1961","journal-title":"Br Med J"},{"key":"10.1016\/j.ejim.2020.04.024_bib0025","first-page":"75","article-title":"and the ACCESS Research Group. Defining organ involvement in sarcoidosis: the ACCESS proposed instrument","volume":"16","author":"Judson","year":"1999","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0026","first-page":"19","article-title":"The WASOG sarcoidosis organ assessment instrument: an update of a previous clinical tool","volume":"31","author":"Judson","year":"2014","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0027","article-title":"Principal component methods \u2013 hierarchical clustering \u2013 partitional clustering: why would we need to choose for visualizing data","author":"Husson","year":"2010","journal-title":"Technical Report"},{"key":"10.1016\/j.ejim.2020.04.024_bib0028","first-page":"268","article-title":"Granulomatous cutaneous sarcoidosis: diagnosis, relationship to systemic disease, prognosis and treatment","volume":"30","author":"Ma\u00f1\u00e1","year":"2013","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"10.1016\/j.ejim.2020.04.024_bib0029","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1164\/rccm.2111053","article-title":"Idiopathic pulmonary fibrosis: a composite physiologic index derived from disease extent observed by computed tomography","volume":"167","author":"Wells","year":"2003","journal-title":"Am J Respir Crit Care Med"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620520301382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620520301382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:33:12Z","timestamp":1760607192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620520301382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":29,"alternative-id":["S0953620520301382"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2020.04.024","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical phenotypes and prediction of chronicity in sarcoidosis using cluster analysis in a prospective cohort of 694 patients","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2020.04.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}