{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T16:22:06Z","timestamp":1778948526504,"version":"3.51.4"},"reference-count":5,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejinme.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.ejim.2021.08.013","type":"journal-article","created":{"date-parts":[[2021,9,5]],"date-time":"2021-09-05T23:50:38Z","timestamp":1630885838000},"page":"109-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Facial hypertrichosis, hyperpigmentation, and hepatosplenomegaly"],"prefix":"10.1016","volume":"92","author":[{"given":"Paola E.","family":"Pizano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0846-024X","authenticated-orcid":false,"given":"Edwin Uriel","family":"Su\u00e1rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9718","key":"10.1016\/j.ejim.2021.08.013_bib0001","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0140-6736(09)61925-5","article-title":"Porphyrias","volume":"375","author":"Puy","year":"2010","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.ejim.2021.08.013_bib0002","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ymgme.2019.01.004","article-title":"Porphyria cutanea tarda: recent update","volume":"128","author":"Singal","year":"2019","journal-title":"Mol Genet Metab"},{"issue":"4","key":"10.1016\/j.ejim.2021.08.013_bib0003","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1600-0781.1997.tb00218.x","article-title":"Porphyria cutanea tarda and hematologic malignancy\u2013a report of 4 cases","volume":"13","author":"McKenna","year":"1997","journal-title":"Photodermatol Photoimmunol Photomed"},{"issue":"1","key":"10.1016\/j.ejim.2021.08.013_bib0004","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/ajh.2830230111","article-title":"Porphyria cutanea tarda in a patient with acute leukaemia","volume":"23","author":"Dutcher","year":"1986","journal-title":"Am J Hematol"},{"issue":"12","key":"10.1016\/j.ejim.2021.08.013_bib0005","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1001\/jama.2016.11260","article-title":"Painless vesicular eruption on the dorsal surfaces of the hands","volume":"316","author":"Shih","year":"2016","journal-title":"JAMA"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620521002867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620521002867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T19:34:41Z","timestamp":1765222481000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620521002867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":5,"alternative-id":["S0953620521002867"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2021.08.013","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Facial hypertrichosis, hyperpigmentation, and hepatosplenomegaly","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2021.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}