{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:46:55Z","timestamp":1793692015247,"version":"4.5.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejinme.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.ejim.2021.11.018","type":"journal-article","created":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T02:27:22Z","timestamp":1638844042000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"special_numbering":"C","title":["Factors associated with persistence of symptoms 1 year after COVID-19: A longitudinal, prospective phone-based interview follow-up cohort study"],"prefix":"10.1016","volume":"97","author":[{"given":"Carlo","family":"Fumagalli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Zocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Tassetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Vittoria","family":"Silverii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Amato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Livi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Giovannoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Verrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Bartoloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Marcucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Lavorini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Fumagalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ungar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iacopo","family":"Olivotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rasero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fattirolli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niccol\u00f3","family":"Marchionni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejim.2021.11.018_bib0001","unstructured":"World Health Organization. WHO coronavirus (COVID-19) emergency dashboard. https:\/\/covid19.who.int. Published, 2021."},{"key":"10.1016\/j.ejim.2021.11.018_bib0002","first-page":"1","article-title":"Clinical Characteristics of Coronavirus Disease 2019 in China","author":"Guan","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2021.11.018_bib0003","article-title":"Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study","volume":"369","author":"Docherty","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.ejim.2021.11.018_bib0004","article-title":"Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study","volume":"369","author":"Petrilli","year":"2020","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.ejim.2021.11.018_bib0005","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41591-021-01283-z","article-title":"Post-acute COVID-19 syndrome","volume":"27","author":"Nalbandian","year":"2021","journal-title":"Nat Med"},{"key":"10.1016\/j.ejim.2021.11.018_bib0006","article-title":"Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline","volume":"372","author":"Shah","year":"2021","journal-title":"BMJ"},{"issue":"6","key":"10.1016\/j.ejim.2021.11.018_bib0007","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1001\/jama.2020.12603","article-title":"Persistent symptoms in patients after acute COVID-19","volume":"324","author":"Carf\u00ec","year":"2020","journal-title":"JAMA - J Am Med Assoc"},{"issue":"2","key":"10.1016\/j.ejim.2021.11.018_bib0008","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.cmi.2020.09.052","article-title":"Follow-up of adults with noncritical COVID-19 two months after symptom onset","volume":"27","author":"Carvalho-Schneider","year":"2021","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"10.1016\/j.ejim.2021.11.018_bib0009","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"Journals Gerontol - Ser A Biol Sci Med Sci"},{"issue":"9","key":"10.1016\/j.ejim.2021.11.018_bib0010","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-040729","article-title":"Clinical risk score to predict in-hospital mortality in COVID-19 patients: a retrospective cohort study","volume":"10","author":"Fumagalli","year":"2020","journal-title":"BMJ Open"},{"issue":"2","key":"10.1016\/j.ejim.2021.11.018_bib0011","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jamda.2016.08.020","article-title":"Ability of Self-Reported Frailty Components to Predict Incident Disability, Falls, and All-Cause Mortality: results From a Population-Based Study of Older British Men","volume":"18","author":"Papachristou","year":"2017","journal-title":"J Am Med Dir Assoc"},{"issue":"4","key":"10.1016\/j.ejim.2021.11.018_bib0012","doi-asserted-by":"crossref","first-page":"576","DOI":"10.7326\/M20-5661","article-title":"Sixty-Day Outcomes Among Patients Hospitalized With COVID-19","volume":"174","author":"Chopra","year":"2021","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.ejim.2021.11.018_bib0013","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1002\/jmv.26368","article-title":"Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: a cross-sectional evaluation","volume":"93","author":"Halpin","year":"2021","journal-title":"J Med Virol"},{"issue":"10270","key":"10.1016\/j.ejim.2021.11.018_bib0014","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0140-6736(20)32656-8","article-title":"6-month consequences of COVID-19 in patients discharged from hospital: a cohort study","volume":"397","author":"Huang","year":"2021","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.ejim.2021.11.018_bib0015","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/s41591-021-01292-y","article-title":"Attributes and predictors of long COVID","volume":"27","author":"Sudre","year":"2021","journal-title":"Nat Med"},{"issue":"9","key":"10.1016\/j.ejim.2021.11.018_bib0016","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.rmed.2007.04.011","article-title":"Sex differences in the incidence and severity of respiratory tract infections","volume":"101","author":"Falagas","year":"2007","journal-title":"Respir Med"},{"issue":"1","key":"10.1016\/j.ejim.2021.11.018_bib0017","first-page":"1","article-title":"Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission","volume":"11","author":"Peckham","year":"2020","journal-title":"Nat Commun 2020 111"},{"issue":"10","key":"10.1016\/j.ejim.2021.11.018_bib0018","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.jagp.2020.07.003","article-title":"Psychological Distress and Its Correlates Among COVID-19 Survivors During Early Convalescence Across Age Groups","volume":"28","author":"Cai","year":"2020","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.ejim.2021.11.018_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2021.100789","article-title":"COPD and the risk of poor outcomes in COVID-19: a systematic review and meta-analysis","volume":"33","author":"Gerayeli","year":"2021","journal-title":"EClinicalMedicine"},{"issue":"2","key":"10.1016\/j.ejim.2021.11.018_bib0020","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02108-2020","article-title":"COVID-19 and COPD","volume":"56","author":"Leung","year":"2020","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.ejim.2021.11.018_bib0021","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in Older Adults: evidence for a Phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J. Gerontol Ser A Biol Sci Med Sci"},{"issue":"8","key":"10.1016\/j.ejim.2021.11.018_bib0022","doi-asserted-by":"crossref","first-page":"e444","DOI":"10.1016\/S2468-2667(20)30146-8","article-title":"The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study","volume":"5","author":"Hewitt","year":"2020","journal-title":"Lancet Public Heal"},{"key":"10.1016\/j.ejim.2021.11.018_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.jamda.2021.05.028","article-title":"Predicting Mortality Risk in Older Hospitalized Persons with COVID-19: a comparison of the COVID-19 Mortality Risk Score with Frailty and Disability","author":"Fumagalli","year":"2021","journal-title":"Journal of the American Medical Directors Association"},{"issue":"3","key":"10.1016\/j.ejim.2021.11.018_bib0024","doi-asserted-by":"crossref","first-page":"e163","DOI":"10.1016\/S2666-7568(21)00006-4","article-title":"Association between Clinical Frailty Scale score and hospital mortality in adult patients with COVID-19 (COMET): an international, multicentre, retrospective, observational cohort study","volume":"2","author":"Sablerolles","year":"2021","journal-title":"Lancet Heal Longev"},{"issue":"7","key":"10.1016\/j.ejim.2021.11.018_bib0025","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1016\/j.mayocp.2021.04.024","article-title":"Post\u2013COVID-19 Syndrome (Long Haul Syndrome): description of a Multidisciplinary Clinic at Mayo Clinic and Characteristics of the Initial Patient Cohort","volume":"96","author":"Vanichkachorn","year":"2021","journal-title":"Mayo Clin Proc"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620521004052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620521004052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:36:25Z","timestamp":1760607385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620521004052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":25,"alternative-id":["S0953620521004052"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2021.11.018","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Factors associated with persistence of symptoms 1 year after COVID-19: A longitudinal, prospective phone-based interview follow-up cohort study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2021.11.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}