{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:01:45Z","timestamp":1771657305927,"version":"3.50.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejinme.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.ejim.2022.08.002","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T19:53:56Z","timestamp":1659988436000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Potential mechanisms of vaccine-induced thrombosis"],"prefix":"10.1016","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8966-6567","authenticated-orcid":false,"given":"Marco","family":"Marietta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Coluccio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Luppi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejim.2022.08.002_bib0001","unstructured":"World Health Organization COVID-19 Dashboard, https:\/\/covid19.who.int\/;2022 [accessed July 25, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0002","unstructured":"European Medicine Agency COVID-19 Vaccines, https:\/\/www.ema.europa.eu\/en\/human-regulatory\/overview\/public-health-threats\/coronavirus-disease-covid-19\/treatments-vaccines\/covid-19-vaccines\/;2022 [accessed July 25, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0003","unstructured":"U.S Food and Drug Administration. COVID-19 Vaccines Authorized for Emergency Use or FDA-Approved, https:\/\/www.fda.gov\/emergency-preparedness-and-response\/coronavirus-disease-2019-covid-19\/covid-19-vaccines#authorized-vaccines\/;2022 [accessed July 25, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0004","unstructured":"World Health Organization. Coronavirus disease (COVID-19): Vaccines, https:\/\/www.who.int\/news-room\/questions-and-answers\/item\/coronavirus-disease-(covid-19)-vaccines\/;2022 [accessed July 25, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0005","unstructured":"London School of Hygiene and Tropical Medicine. COVID-19 vaccine tracker, https:\/\/www.lshtm.ac.uk\/research\/centres\/vaccine-centre\/covid-19\/;2022 [accessed July 25, 2022]."},{"issue":"22","key":"10.1016\/j.ejim.2022.08.002_bib0006","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1056\/NEJMe2204695","article-title":"Does the world still need new COVID-19 vaccines?","volume":"386","author":"Nohynek","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0007","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1056\/NEJMoa2201300","article-title":"Efficacy and safety of a recombinant plant-based adjuvanted COVID-19 vaccine","volume":"386","author":"Hager","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0008","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1056\/NEJMoa2202261","article-title":"Efficacy and safety of the RBD-dimer-based COVID-19 vaccine ZF2001 in adults","volume":"386","author":"Dai","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0009","unstructured":"Center for Disease Control and Prevention. The Vaccine Adverse Events Reporting System (VAERS), https:\/\/covid.cdc.gov\/covid-data-tracker\/#vaccinations_vacc-total-admin-rate-total\/;2022 [accessed April 20, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0010","unstructured":"UK Government. Medicines and Healthcare products Regulatory Agency. Coronavirus vaccine-weekly summary of Yellow Card reporting. Updated 22 July 2022, https:\/\/www.gov.uk\/government\/publications\/coronavirus-covid-19-vaccine-adverse-reactions\/coronavirus-vaccine-summary-of-yellow-card-reporting\/;2022 [accessed July 25, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0011","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/bjh.18005","article-title":"Life-changing consequences of vaccine-induced immune-mediated thrombosis with thrombocytopenia","volume":"197","author":"Smith","year":"2022","journal-title":"Br J Haematol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0012","doi-asserted-by":"crossref","first-page":"5872","DOI":"10.1016\/j.vaccine.2017.08.086","article-title":"Risk of venous thromboembolism following influenza vaccination in adults aged 50 years and older in the vaccine safety datalink","volume":"35","author":"Vickers","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.ejim.2022.08.002_bib0013","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ejim.2022.03.002","article-title":"Thrombotic events following COVID-19 vaccines compared to influenza vaccines","volume":"99","author":"Vallone","year":"2022","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0014","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S1473-3099(21)00224-3","article-title":"Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID symptom study app in the UK: a prospective observational study","volume":"21","author":"Menni","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ejim.2022.08.002_bib0015","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1056\/NEJMoa2104840","article-title":"Thrombotic thrombocytopenia after ChAdOx1 nCoV-19 vaccination","volume":"384","author":"Greinacher","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0016","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1056\/NEJMoa2104882","article-title":"Thrombosis and thrombocytopenia after ChAdOx1 nCoV-19 vaccination","volume":"384","author":"Schultz","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0017","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1056\/NEJMoa2105385","article-title":"Pathologic antibodies to platelet factor 4 after ChAdOx1 nCoV-19 vaccination","volume":"384","author":"Scully","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0018","doi-asserted-by":"crossref","first-page":"n699","DOI":"10.1136\/bmj.n699","article-title":"COVID-19: European countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots","volume":"372","author":"Wise","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.ejim.2022.08.002_bib0019","unstructured":"European Medicine Agency news. AstraZeneca\u2019s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets, https:\/\/www.ema.europa.eu\/en\/news\/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood\/;2021 [accessed June 5, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0020","unstructured":"World Health Organization. Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19), https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/342999\/WHO-2019-nCoV-TTS-2021.1-eng.pdf\/;2021 [accessed June 5, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0021","first-page":"281","article-title":"Management of cerebral and splanchnic vein thrombosis associated with thrombocytopenia in subjects previously vaccinated with Vaxzevria (AstraZeneca): a position statement from the Italian society for the study of haemostasis and thrombosis (SISET)","volume":"19","author":"Gresele","year":"2021","journal-title":"Blood Transfus"},{"key":"10.1016\/j.ejim.2022.08.002_bib0022","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1055\/a-1469-7481","article-title":"Diagnosis and management of vaccine-related thrombosis following AstraZeneca COVID-19 vaccination: guidance statement from the GTH","volume":"41","author":"Oldenburg","year":"2021","journal-title":"Hamostaseologie"},{"key":"10.1016\/j.ejim.2022.08.002_bib0023","doi-asserted-by":"crossref","first-page":"e12529","DOI":"10.1002\/rth2.12529","article-title":"Vaccine-induced immune thrombocytopenia and thrombosis (VITT)","volume":"5","author":"Makris","year":"2021","journal-title":"Res Pract Thromb Haemost"},{"key":"10.1016\/j.ejim.2022.08.002_bib0024","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S2352-3026(21)00306-9","article-title":"Vaccine-induced immune thrombotic thrombocytopenia","volume":"9","author":"Klok","year":"2021","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0025","first-page":"14","article-title":"Heparin induced thrombocytopenia: position paper from the Italian society on thrombosis and haemostasis (SISET)","volume":"19","author":"Marcucci","year":"2021","journal-title":"Blood Transfus"},{"key":"10.1016\/j.ejim.2022.08.002_bib0026","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1111\/jth.13813","article-title":"Autoimmune heparin-induced thrombocytopenia","volume":"15","author":"Greinacher","year":"2017","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.ejim.2022.08.002_bib0027","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1001\/jama.2021.7517","article-title":"US case reports of cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccination, March 2 to April 21, 2021","volume":"325","author":"See","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.ejim.2022.08.002_bib0028","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.7326\/L21-0244","article-title":"Thrombosis with thrombocytopenia after the messenger RNA-1273 vaccine","volume":"174","author":"Sangli","year":"2021","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0029","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.7326\/M21-2680","article-title":"Thrombosis after vaccination with messenger RNA-1273: is this vaccine-induced thrombosis and thrombocytopenia or thrombosis with thrombocytopenia syndrome?","volume":"174","author":"Pishko","year":"2021","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0030","doi-asserted-by":"crossref","first-page":"e12750","DOI":"10.1002\/rth2.12750","article-title":"Thrombotic thrombocytopenia after Sinopharm BBIBP-CorV COVID-19 vaccination","volume":"6","author":"Hosseinzadeh","year":"2022","journal-title":"Res Pract Thromb Haemost"},{"key":"10.1016\/j.ejim.2022.08.002_bib0031","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/jth.15604","article-title":"Thrombosis and thrombocytopenia after HPV vaccination","volume":"20","author":"Johansen","year":"2022","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.ejim.2022.08.002_bib0032","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/s41591-021-01408-4","article-title":"First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland","volume":"27","author":"Simpson","year":"2021","journal-title":"Nat Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0033","article-title":"Risk of venous thrombotic events and thrombocytopenia in sequential time periods after ChAdOx1 and BNT162b2 COVID-19 vaccines: a national cohort study in England","volume":"13","author":"Andrews","year":"2022","journal-title":"Lancet Reg Health Eur"},{"key":"10.1016\/j.ejim.2022.08.002_bib0034","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003926","article-title":"Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: a population-based cohort study of 46 million adults in England","volume":"19","author":"Whiteley","year":"2022","journal-title":"PLoS Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003927","article-title":"First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations, and cerebral venous sinus thrombosis: a pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales","volume":"19","author":"Kerr","year":"2022","journal-title":"PLoS Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0036","unstructured":"Centers for Disease Control and Prevention. Vaccine Adverse Event Reporting System (VAERS), https:\/\/wonder.cdc.gov\/controller\/datarequest\/D8;jsessionid=AC239F4CF07390490F345CAC38C5\/;2022 [accessed on June 30, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0037","unstructured":"Centers for Disease Control and Prevention. COVID Data Tracker, https:\/\/covid.cdc.gov\/covid-data-tracker\/#vaccinations_vacc-total-admin-rate-total\/;2022 [accessed on June 30, 2022]."},{"key":"10.1016\/j.ejim.2022.08.002_bib0038","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1182\/blood.2021011958","article-title":"Prothrombotic immune thrombocytopenia after COVID-19 vaccination","volume":"138","author":"Tiede","year":"2021","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102662","article-title":"Mechanisms of immunothrombosis in vaccine-induced thrombotic thrombocytopenia (VITT) compared to natural SARS-CoV-2 infection","volume":"121","author":"McGonagle","year":"2021","journal-title":"J Autoimmun"},{"issue":"22","key":"10.1016\/j.ejim.2022.08.002_bib0040","article-title":"Thrombosis and thrombocytopenia in COVID-19 and after COVID-19 vaccination","volume":"S1050-1738","author":"Iba","year":"2022","journal-title":"Trends Cardiovasc Med"},{"issue":"2","key":"10.1016\/j.ejim.2022.08.002_bib0041","doi-asserted-by":"crossref","first-page":"140","DOI":"10.7861\/clinmed.2022-0006","article-title":"The aetiopathogenesis of vaccine-induced immune thrombotic thrombocytopenia","volume":"22","author":"Toh","year":"2022","journal-title":"Clin Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0042","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1053\/j.seminhematol.2022.02.004","article-title":"Pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT)","volume":"59","author":"Greinacher","year":"2022","journal-title":"Semin Hematol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0043","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/s41586-021-03744-4","article-title":"Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia","volume":"596","author":"Huynh","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ejim.2022.08.002_bib0044","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/d41586-021-02291-2","article-title":"COVID vaccines and blood clots: what researchers know so far","volume":"596","author":"Ledford","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.ejim.2022.08.002_bib0045","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3324\/haematol.2021.280154","article-title":"Comparative analysis of ChAdOx1nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines","volume":"107","author":"Michalik","year":"2022","journal-title":"Haematologica"},{"key":"10.1016\/j.ejim.2022.08.002_bib0046","doi-asserted-by":"crossref","first-page":"e74974","DOI":"10.7554\/eLife.74974","article-title":"Vaccine-induced COVID-19 mimicry syndrome","volume":"11","author":"Kowarz","year":"2022","journal-title":"eLife"},{"key":"10.1016\/j.ejim.2022.08.002_bib0047","doi-asserted-by":"crossref","first-page":"10791","DOI":"10.3390\/ijms221910791","article-title":"Coagulopathies after vaccination against SARS-CoV-2 may be derived from a combined effect of SARS-CoV-2 spike protein and adenovirus vector-triggered signaling pathways","volume":"22","author":"Kircheis","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ejim.2022.08.002_bib0048","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.779453","article-title":"Inflammation and platelet activation after COVID-19 vaccines -possible mechanisms behind vaccine-induced immune thrombocytopenia and thrombosis","volume":"12","author":"Ostrowski","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0049","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1053\/j.seminhematol.2022.03.001","article-title":"Longitudinal aspects of VITT","volume":"59","author":"Sch\u00f6nborn","year":"2022","journal-title":"Semin Hematol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0050","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1056\/NEJMc2112760","article-title":"Decline in pathogenic antibodies over time in VITT","volume":"385","author":"Sch\u00f6nborn","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejim.2022.08.002_bib0051","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1182\/blood.2021014214","article-title":"Most anti-PF4 antibodies in vaccine-induced immune thrombotic thrombocytopenia are transient","volume":"139","author":"Sch\u00f6nborn","year":"2022","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0052","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1182\/blood.2021014684","article-title":"Natural history of PF4 antibodies in vaccine-induced immune thrombocytopenia and thrombosis","volume":"139","author":"Craven","year":"2022","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0053","first-page":"191813","article-title":"An observational study to identify the prevalence of thrombocytopenia and anti-PF4\/polyanion antibodies in Norwegian health care workers after COVID-19 vaccination","author":"S\u00f8rvoll","year":"2021","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.ejim.2022.08.002_bib0054","doi-asserted-by":"crossref","first-page":"7961","DOI":"10.1038\/s41598-022-11623-9","article-title":"Serum levels of anti-PF4 IgG after AZD1222 (ChAdOx1 nCoV-19) vaccination","volume":"12","author":"Cohen","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejim.2022.08.002_bib0055","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1182\/blood.2021012217","article-title":"Frequency of positive anti-PF4\/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2","volume":"138","author":"Thiele","year":"2021","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0056","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1182\/blood-2011-03-342857","article-title":"Association of natural anti-platelet factor 4\/heparin antibodies with periodontal disease","volume":"118","author":"Greinacher","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0057","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1182\/blood-2013-11-540781","article-title":"B-cell tolerance regulates production of anti- bodies causing heparin-induced thrombocytopenia","volume":"123","author":"Zheng","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0058","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1182\/blood-2013-01-478966","article-title":"Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4","volume":"122","author":"Jaax","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0059","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1182\/blood-2015-02-631135","article-title":"Anti-miR-148a regulates platelet Fc\u03b3RIIA signaling and decreases thrombosis in vivo in mice","volume":"126","author":"Zhou","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.ejim.2022.08.002_bib0060","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.879157","article-title":"Insights into immunothrombotic mechanisms in acute stroke due to vaccine-induced immune thrombotic thrombocytopenia","volume":"13","author":"de Buhr","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.ejim.2022.08.002_bib0061","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ejim.2022.03.011","article-title":"The precautionary principle in the COVID-19 vaccination campaign: the complicated relationship between the scientific community, medicines regulatory agencies and citizens","volume":"101","author":"Lobello","year":"2022","journal-title":"Eur J Intern Med"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620522002746?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620522002746?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T09:36:25Z","timestamp":1760607385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620522002746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":61,"alternative-id":["S0953620522002746"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2022.08.002","relation":{},"ISSN":["0953-6205"],"issn-type":[{"value":"0953-6205","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential mechanisms of vaccine-induced thrombosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2022.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}