{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T23:40:20Z","timestamp":1737675620760,"version":"3.33.0"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","ejinme.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Internal Medicine"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.ejim.2023.11.033","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T20:08:47Z","timestamp":1702152527000},"page":"42-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Asymptomatic hyperuricemia and cardiovascular mortality: A matter of mechanisms?"],"prefix":"10.1016","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1238-872X","authenticated-orcid":false,"given":"Roberto","family":"Pontremoli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Carla","family":"Ghinatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Barnini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ejim.2023.11.033_bib0001","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1053\/j.ajkd.2017.12.009","article-title":"Acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a scientific workshop organized by the national kidney foundation","volume":"71","author":"Johnson","year":"2018","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.ejim.2023.11.033_bib0002","doi-asserted-by":"crossref","unstructured":"Viazzi F., Leoncini G., Ratto E., Pontremoli R., High blood press cardiovasc prev hyperuricemia and renal risk. Int J Mol Sci, 2014 Sep;21(3):189\u201394.","DOI":"10.1007\/s40292-014-0042-7"},{"issue":"Suppl 3","key":"10.1016\/j.ejim.2023.11.033_bib0003","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1185\/03007995.2013.790803","article-title":"Serum uric acid and cardio-renal diseases","author":"Ruilope","year":"2013","journal-title":"Curr Med Res Opin"},{"issue":"12","key":"10.1016\/j.ejim.2023.11.033_bib0004","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1097\/HJH.0000000000003480","volume":"41","author":"Mancia","year":"2023","journal-title":"J Hypertens"},{"issue":"12","key":"10.1016\/j.ejim.2023.11.033_bib0005","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s11906-020-01116-3","article-title":"Management of hyperuricemia in patients with chronic kidney disease: a focus on renal protection","volume":"22","author":"Kielstein","year":"2020","journal-title":"Curr Hypertens Rep"},{"issue":"17","key":"10.1016\/j.ejim.2023.11.033_bib0006","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1056\/NEJMra0800885","article-title":"Uric acid and cardiovascular risk","volume":"359","author":"Feig","year":"2008","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.ejim.2023.11.033_bib0007","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1002\/oby.23540","article-title":"Do thrifty genes exist? Revisiting uricase","volume":"30","author":"Johnson","year":"2022","journal-title":"Obesity (Silver Spring)"},{"issue":"9","key":"10.1016\/j.ejim.2023.11.033_bib0008","first-page":"1295","article-title":"Is it time to revise the normal range of serum uric acid levels?","volume":"18","author":"Desideri","year":"2014","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"3","key":"10.1016\/j.ejim.2023.11.033_bib0009","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1161\/HYPERTENSIONAHA.115.06531","article-title":"Urate-lowering drugs and prevention of cardiovascular disease: the emerging role of xanthine oxidase inhibition","volume":"67","author":"Borghi","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.ejim.2023.11.033_bib0010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejim.2023.04.006","article-title":"Xanthine oxidase inhibition and cardiovascular protection: don't shoot in the dark","volume":"113","author":"Desideri","year":"2023","journal-title":"Eur J Intern Med"},{"issue":"1","key":"10.1016\/j.ejim.2023.11.033_bib0011","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s40620-021-00985-4","article-title":"Association of uric acid with kidney function and albuminuria: the Uric AcidRight for heArt health (URRAH) project","volume":"35","author":"Russo","year":"2022","journal-title":"J Nephrol."},{"key":"10.1016\/j.ejim.2023.11.033_bib0012","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ejim.2023.10.009","article-title":"Hyperuricaemia-associated all-cause mortality risk effect is increased by non-impaired kidney function - Is renal hyperuricaemia less dangerous?","volume":"121","author":"Timsans","year":"2024","journal-title":"Eur J Intern Med"},{"issue":"3","key":"10.1016\/j.ejim.2023.11.033_bib0013","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/j.1523-1755.2004.00484.x","article-title":"LIFE study groupthe impact of serum uric acid on cardiovascular outcomes in the life study","volume":"65","author":"H\u00f8ieggen","year":"2004","journal-title":"Kidney Int"},{"issue":"3","key":"10.1016\/j.ejim.2023.11.033_bib0014","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/ejhf.1056","article-title":"PARADIGM-HF investigators and committees. sacubitril\/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF","volume":"20","author":"Mogensen","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.ejim.2023.11.033_bib0015","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7520632","article-title":"Impacts of sodium\/Glucose cotransporter-2 inhibitors on circulating Uric acidconcentrations: a systematic review and meta-analysis","volume":"2022","author":"Akbari","year":"2022","journal-title":"J Diabetes Res"}],"container-title":["European Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620523004296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0953620523004296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T03:26:26Z","timestamp":1737602786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0953620523004296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":15,"alternative-id":["S0953620523004296"],"URL":"https:\/\/doi.org\/10.1016\/j.ejim.2023.11.033","relation":{},"ISSN":["0953-6205"],"issn-type":[{"type":"print","value":"0953-6205"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Asymptomatic hyperuricemia and cardiovascular mortality: A matter of mechanisms?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Internal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejim.2023.11.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}