{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:19:40Z","timestamp":1791404380973,"version":"4.3.3"},"reference-count":23,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.ejmech.2009.04.001","type":"journal-article","created":{"date-parts":[[2009,4,9]],"date-time":"2009-04-09T04:32:49Z","timestamp":1239251569000},"page":"3680-3686","source":"Crossref","is-referenced-by-count":97,"title":["Synthesis of new acridines and hydrazones derived from cyclic \u03b2-diketone for cytotoxic and antiviral evaluation"],"prefix":"10.1016","volume":"44","author":[{"given":"Osama I.","family":"El-Sabbagh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanaa M.","family":"Rady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2009.04.001_bib1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.bbrc.2004.03.194","volume":"318","author":"Kanda","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejmech.2009.04.001_bib2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1365-2893.2000.00019.x","volume":"7","author":"Vento","year":"2000","journal-title":"J. Viral Hepat."},{"key":"10.1016\/j.ejmech.2009.04.001_bib3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0968-0896(01)00249-8","volume":"10","author":"Spicer","year":"2002","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib4","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0968-0896(02)00442-X","volume":"11","author":"Antonini","year":"2003","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib5","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.ejmech.2004.06.015","volume":"39","author":"Santelli-Rouvier","year":"2004","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib6","volume":"14","author":"Kamal","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2009.04.001_bib7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0223-5234(02)01348-X","volume":"37","author":"Bran","year":"2002","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib8","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1016\/j.bmc.2007.02.041","volume":"15","author":"Rzeski","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib9","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.bmcl.2006.11.060","volume":"17","author":"Wu","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2009.04.001_bib10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.ejmech.2007.04.010","volume":"43","author":"Kucukguzel","year":"2008","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib11","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1016\/j.bmcl.2007.12.063","volume":"18","author":"Kamal","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2009.04.001_bib12","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.ejmech.2007.03.033","volume":"43","author":"Sztanke","year":"2008","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib13","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0223-5234(03)00138-7","volume":"38","author":"Terzioglu","year":"2003","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib14","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0223-5234(00)01201-0","volume":"36","author":"Modzelewska-Banachiewicz","year":"2001","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib15","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.ejmech.2006.12.038","volume":"42","author":"Kucukguzel","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib16","first-page":"73","volume":"ix","author":"Lichitsky","year":"2001","journal-title":"ARKIVOC"},{"key":"10.1016\/j.ejmech.2009.04.001_bib17","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1021\/jm00093a012","volume":"35","author":"Edafiogho","year":"1992","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib18","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00706-007-0586-5","volume":"138","author":"El-Sadek","year":"2007","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.ejmech.2009.04.001_bib19","first-page":"131","volume":"3","author":"El-Sabbagh","year":"1994","journal-title":"Zag. J. Pharm. Sci."},{"key":"10.1016\/j.ejmech.2009.04.001_bib20","first-page":"12","volume":"41","author":"El-Sadek","year":"2007","journal-title":"Khim. Farm. Zh."},{"key":"10.1016\/j.ejmech.2009.04.001_bib21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.ejmech.2009.04.001_bib22","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1590\/S0074-02761999000400019","volume":"94","author":"Betancur-Galvis","year":"1999","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.ejmech.2009.04.001_bib23","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1128\/AAC.39.6.1287","volume":"39","author":"Tebas","year":"1995","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523409002013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523409002013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T10:23:38Z","timestamp":1545301418000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523409002013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S0223523409002013"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2009.04.001","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}