{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:20:49Z","timestamp":1790011249811,"version":"4.0.1"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.ejmech.2012.02.026","type":"journal-article","created":{"date-parts":[[2012,2,18]],"date-time":"2012-02-18T13:01:58Z","timestamp":1329570118000},"page":"405-415","source":"Crossref","is-referenced-by-count":84,"special_numbering":"C","title":["Evaluation of DNA binding, antioxidant and cytotoxic activity of mononuclear Co(III) complexes of 2-oxo-1,2-dihydrobenzo[h]quinoline-3-carbaldehyde thiosemicarbazones"],"prefix":"10.1016","volume":"50","author":[{"given":"Eswaran","family":"Ramachandran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajesh P.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paramasivan","family":"Poornima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palaniappan","family":"Kalaivani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rathinasabapathi","family":"Prabhakaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viswanadha Vijaya","family":"Padma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karuppannan","family":"Natarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2012.02.026_bib1","first-page":"1663","volume":"10","author":"Boulikas","year":"2003","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.ejmech.2012.02.026_bib2","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1021\/cr980420v","volume":"99","author":"Wong","year":"1999","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ejmech.2012.02.026_bib3","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.2174\/1381612033454180","volume":"9","author":"Galanski","year":"2003","journal-title":"Curr. Pharm. Des"},{"key":"10.1016\/j.ejmech.2012.02.026_bib4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nrd1691","volume":"4","author":"Wang","year":"2005","journal-title":"J.\u00a0Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ejmech.2012.02.026_bib5","first-page":"1","volume":"vol. 6","author":"Bernhardt","year":"2003"},{"key":"10.1016\/j.ejmech.2012.02.026_bib6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ejmech.2010.10.030","volume":"46","author":"Vinuelas-Zahinos","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib7","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1021\/jm049529n","volume":"48","author":"Ferrari","year":"2005","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0162-0134(00)00181-1","volume":"83","author":"Ferrari","year":"2001","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib9","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1023\/A:1018598810355","volume":"22","author":"West","year":"1997","journal-title":"Trans. Met. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib10","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s11243-006-0161-7","volume":"32","author":"Peng","year":"2007","journal-title":"Trans. Met. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib11","doi-asserted-by":"crossref","first-page":"9670","DOI":"10.1021\/ja0521674","volume":"127","author":"Nordell","year":"2005","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.ejmech.2012.02.026_bib12","doi-asserted-by":"crossref","first-page":"8712","DOI":"10.1016\/j.bmc.2006.07.061","volume":"14","author":"Barraja","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib13","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1021\/jo0480545","volume":"70","author":"Kuethe","year":"2005","journal-title":"J.\u00a0Org. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib14","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1021\/jm00160a038","volume":"29","author":"DeRuiter","year":"1986","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib15","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/S0960-894X(02)00240-8","volume":"12","author":"Hewawasam","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2012.02.026_bib16","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1016\/j.ejmech.2011.07.038","volume":"46","author":"Raja","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib17","doi-asserted-by":"crossref","first-page":"12852","DOI":"10.1021\/ic2020308","volume":"50","author":"Raja","year":"2011","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib18","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1039\/C0MT00062K","volume":"3","author":"Prabhakaran","year":"2011","journal-title":"Metallomics"},{"key":"10.1016\/j.ejmech.2012.02.026_bib19","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1039\/C1MT00143D","volume":"4","author":"Ramachandran","year":"2012","journal-title":"Metallomics"},{"key":"10.1016\/j.ejmech.2012.02.026_bib20","author":"Ramachandran","year":"2011","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.ejmech.2012.02.026_bib21","doi-asserted-by":"crossref","first-page":"4548","DOI":"10.1039\/c0dt01657h","volume":"40","author":"Raja","year":"2011","journal-title":"Dalton Trans."},{"key":"10.1016\/j.ejmech.2012.02.026_bib22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1039\/C1MT00144B","volume":"4","author":"Kalaivani","year":"2012","journal-title":"Metallomics"},{"key":"10.1016\/j.ejmech.2012.02.026_bib23","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.poly.2006.08.029","volume":"26","author":"Rapheal","year":"2007","journal-title":"Polyhedron"},{"key":"10.1016\/j.ejmech.2012.02.026_bib24","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1016\/j.ica.2004.02.013","volume":"357","author":"Rodriguez-Arguelles","year":"2004","journal-title":"Inorg. Chim. Acta"},{"key":"10.1016\/j.ejmech.2012.02.026_bib25","doi-asserted-by":"crossref","first-page":"12091","DOI":"10.1021\/bi001236i","volume":"39","author":"Tanious","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2012.02.026_bib26","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jinorgbio.2006.07.011","volume":"101","author":"Zhong","year":"2007","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib27","doi-asserted-by":"crossref","first-page":"4477","DOI":"10.1016\/j.ejmech.2009.06.009","volume":"44","author":"Liu","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib28","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.1016\/j.ejmech.2010.08.060","volume":"45","author":"Liu","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib29","doi-asserted-by":"crossref","first-page":"6392","DOI":"10.1021\/bi00394a013","volume":"26","author":"Wolf","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2012.02.026_bib30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejmech.2011.10.024","volume":"47","author":"Raja","year":"2012","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib31","doi-asserted-by":"crossref","first-page":"4246","DOI":"10.1021\/bi00067a012","volume":"32","author":"Meyer-Almes","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2012.02.026_bib32","first-page":"339","volume":"19","author":"Howe","year":"1976","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2012.02.026_bib33","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/S0162-0134(03)00313-1","volume":"97","author":"Zeng","year":"2003","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib34","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jinorgbio.2008.09.010","volume":"103","author":"Senthil Kumar","year":"2009","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib35","doi-asserted-by":"crossref","first-page":"9319","DOI":"10.1021\/bi00154a001","volume":"31","author":"Satyanarayana","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2012.02.026_bib36","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.jinorgbio.2006.02.003","volume":"100","author":"Lawrence","year":"2006","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib37","doi-asserted-by":"crossref","first-page":"10757","DOI":"10.1039\/b915081a","author":"Beckford","year":"2009","journal-title":"Dalton Trans."},{"key":"10.1016\/j.ejmech.2012.02.026_bib38","doi-asserted-by":"crossref","first-page":"7162","DOI":"10.1073\/pnas.92.16.7162","volume":"92","author":"Bonfoco","year":"1995","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ejmech.2012.02.026_bib39","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0168-1656(92)90158-6","volume":"25","author":"Legrand","year":"1992","journal-title":"J.\u00a0Biotechnol."},{"key":"10.1016\/j.ejmech.2012.02.026_bib40","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1073\/pnas.91.5.1691","volume":"91","author":"Yu","year":"1994","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ejmech.2012.02.026_bib41","doi-asserted-by":"crossref","first-page":"5987","DOI":"10.1016\/j.tetlet.2007.06.127","volume":"48","author":"Singh","year":"2007","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.ejmech.2012.02.026_bib42","series-title":"Text Book of Practical Organic Chemistry","author":"Vogel","year":"1989"},{"key":"10.1016\/j.ejmech.2012.02.026_bib43","series-title":"CrysAlis PRO CCD and CrysAlis PRO RED","author":"Oxford Diffraction","year":"2009"},{"key":"10.1016\/j.ejmech.2012.02.026_bib44","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1107\/S0108767307043930","volume":"64","author":"Sheldrick","year":"2008","journal-title":"Acta Crystallogr. Sect. A"},{"key":"10.1016\/j.ejmech.2012.02.026_bib45","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1107\/S0021889899006020","volume":"32","author":"Farrugia","year":"1999","journal-title":"J.\u00a0Appl. Crystallogr."},{"key":"10.1016\/j.ejmech.2012.02.026_bib46","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1107\/S0021889897003117","volume":"30","author":"Farrugia","year":"1997","journal-title":"J.\u00a0Appl. Crystallogr."},{"key":"10.1016\/j.ejmech.2012.02.026_bib47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1107\/S0021889802022112","volume":"36","author":"Spek","year":"2003","journal-title":"J.\u00a0Appl. Crystallogr."},{"key":"10.1016\/j.ejmech.2012.02.026_bib48","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/bip.1969.360080105","volume":"8","author":"Cohen","year":"1969","journal-title":"Biopolymers"},{"key":"10.1016\/j.ejmech.2012.02.026_bib49","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/1811199a0","volume":"181","author":"Blois","year":"1958","journal-title":"Nature"},{"key":"10.1016\/j.ejmech.2012.02.026_bib50","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1021\/jf9913458","volume":"48","author":"Pulido","year":"2000","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.ejmech.2012.02.026_bib51","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","volume":"65","author":"Mossman","year":"1983","journal-title":"J.\u00a0Immunol. Methods"},{"key":"10.1016\/j.ejmech.2012.02.026_bib52","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1056\/NEJM195609062551001","volume":"255","author":"Wacker","year":"1956","journal-title":"New Eng. J. Med."},{"key":"10.1016\/j.ejmech.2012.02.026_bib53","doi-asserted-by":"crossref","first-page":"518","DOI":"10.4049\/jimmunol.139.2.518","volume":"139","author":"Stueher","year":"1987","journal-title":"J.\u00a0Immunol."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523412001171?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523412001171?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T17:12:20Z","timestamp":1686762740000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523412001171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":53,"alternative-id":["S0223523412001171"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2012.02.026","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}