{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:46:27Z","timestamp":1788871587822,"version":"build-2803163510"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,6]],"date-time":"2014-01-06T00:00:00Z","timestamp":1388966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"Queensland Smart State Innovation Project Fund"},{"name":"NIH","award":["AI75641"],"award-info":[{"award-number":["AI75641"]}]},{"name":"NIH","award":["AI78962"],"award-info":[{"award-number":["AI78962"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.ejmech.2013.12.050","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T23:34:00Z","timestamp":1389224040000},"page":"541-551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["N1,N1-Dimethyl-N3-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis"],"prefix":"10.1016","volume":"74","author":[{"given":"Ngoc B.","family":"Pham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Deydier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Labaied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Monnerat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Stuart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.","family":"Quinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2013.12.050_bib1","unstructured":"World Health Organization, http:\/\/www.who.int\/mediacentre\/factsheets\/fs259\/en\/, (accessed 27.08.13)."},{"key":"10.1016\/j.ejmech.2013.12.050_bib2","unstructured":"Drugs for Neglected Disease Initiative, http:\/www.dndi.org.\/newsletters\/n14\/page2.htm, (accessed 13.08.13)."},{"key":"10.1016\/j.ejmech.2013.12.050_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/cid\/cis886","volume":"56","author":"Alirol","year":"2013","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ejmech.2013.12.050_bib4","doi-asserted-by":"crossref","first-page":"6615","DOI":"10.1016\/j.bmc.2011.06.006","volume":"19","author":"Davis","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2013.12.050_bib5","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1021\/cn200100h","volume":"3","author":"Ghose","year":"2012","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.ejmech.2013.12.050_bib6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1602\/neurorx.2.4.541","volume":"2","author":"Pajouhesh","year":"2005","journal-title":"NeuroRx"},{"key":"10.1016\/j.ejmech.2013.12.050_bib7","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1016\/S0957-4166(02)00586-4","volume":"20","author":"Osuna","year":"2002","journal-title":"Tetrahedron: Asymmetry"},{"key":"10.1016\/j.ejmech.2013.12.050_bib8","doi-asserted-by":"crossref","first-page":"6293","DOI":"10.1016\/S0040-4020(98)00326-3","volume":"54","author":"Varma","year":"1998","journal-title":"Tetrahedron"},{"key":"10.1016\/j.ejmech.2013.12.050_bib9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1039\/b401620c","volume":"6","author":"Ju","year":"2004","journal-title":"Green Chem."},{"key":"10.1016\/j.ejmech.2013.12.050_bib10","doi-asserted-by":"crossref","first-page":"7785","DOI":"10.1016\/S0040-4020(01)00722-0","volume":"57","author":"Salvatore","year":"2001","journal-title":"Tetrahedron"},{"key":"10.1016\/j.ejmech.2013.12.050_bib11","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1002\/ejoc.200600937","volume":"8","author":"Singh","year":"2007","journal-title":"Eur. J. Org. Chem."},{"key":"10.1016\/j.ejmech.2013.12.050_bib12","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1021\/jo010643c","volume":"67","author":"Salvatore","year":"2002","journal-title":"J.\u00a0Org. Chem."},{"key":"10.1016\/j.ejmech.2013.12.050_bib13","doi-asserted-by":"crossref","first-page":"777","DOI":"10.4155\/fmc.09.65","volume":"1","author":"Filler","year":"2009","journal-title":"Future Med. Chem."},{"key":"10.1016\/j.ejmech.2013.12.050_bib14","doi-asserted-by":"crossref","first-page":"665","DOI":"10.4269\/ajtmh.2009.09-0015","volume":"81","author":"Sykes","year":"2009","journal-title":"Am. J. Trop. Med. Hyg."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523414000129?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523414000129?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T08:26:22Z","timestamp":1538900782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523414000129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":14,"alternative-id":["S0223523414000129"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2013.12.050","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"N1,N1-Dimethyl-N3-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmech.2013.12.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}]}}