{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:03:47Z","timestamp":1781762627875,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Higher Education Commission","award":["20-1910"],"award-info":[{"award-number":["20-1910"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.ejmech.2015.03.018","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T01:33:25Z","timestamp":1426037605000},"page":"199-209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"special_numbering":"C","title":["Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast \u03b1-glucosidase"],"prefix":"10.1016","volume":"95","author":[{"given":"Huma","family":"Niaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamdy","family":"Kashtoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalaluddin A.J.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajmal","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atia-tul-","family":"Wahab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Tanveer","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid Mohammed","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahnaz","family":"Perveen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Iqbal","family":"Choudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2015.03.018_bib1","first-page":"1","volume":"18","author":"Venkateswarlu","year":"2012","journal-title":"Int. J. Ind. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib2","doi-asserted-by":"crossref","first-page":"783","DOI":"10.13005\/ojc\/290260","volume":"2","author":"Keyhani","year":"2013","journal-title":"Orient. J. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib3","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3390\/80400381","volume":"8","author":"Eynde","year":"2003","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2015.03.018_bib4","first-page":"826","volume":"45B","author":"Nagarajan","year":"2006","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib5","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1021\/jf001251u","volume":"49","author":"Matsui","year":"2001","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib6","first-page":"1515","volume":"83","author":"Hudson","year":"2002","journal-title":"Curr. Sci."},{"key":"10.1016\/j.ejmech.2015.03.018_bib7","doi-asserted-by":"crossref","first-page":"5900","DOI":"10.1016\/j.bmcl.2013.08.084","volume":"23","author":"Fatmawati","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2015.03.018_bib8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/bmj.321.7258.405","volume":"321","author":"Stratton","year":"2000","journal-title":"BMJ"},{"key":"10.1016\/j.ejmech.2015.03.018_bib9","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1007\/s001250100020","volume":"44","author":"Bonora","year":"2001","journal-title":"Diabetologia"},{"key":"10.1016\/j.ejmech.2015.03.018_bib10","first-page":"775","volume":"4","author":"Kahn","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejmech.2015.03.018_bib11","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1093\/ajhp\/53.19.2277","volume":"53","author":"Martin","year":"1996","journal-title":"Am. J. Health Syst. Pharm."},{"key":"10.1016\/j.ejmech.2015.03.018_bib12","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1080\/14756360802565346","volume":"24","author":"Chougale","year":"2009","journal-title":"J.\u00a0Enyzme Inhib. Med. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib13","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.3390\/ijms14022903","volume":"14","author":"Mart\u00ednez","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejmech.2015.03.018_bib14","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1134\/S106816201303014X","volume":"3","author":"Sharma","year":"2013","journal-title":"Russ. J. Bioorg. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib15","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1080\/17518253.2013.781686","volume":"3","author":"Yang","year":"2013","journal-title":"Green. Chem. Lett. Rev."},{"key":"10.1016\/j.ejmech.2015.03.018_bib16","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.tetlet.2009.12.098","volume":"51","author":"Tamaddon","year":"2010","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.ejmech.2015.03.018_bib17","first-page":"279","volume":"2","author":"Tale","year":"2013","journal-title":"Eur. Chem. Bull."},{"key":"10.1016\/j.ejmech.2015.03.018_bib18","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1016\/j.tetlet.2014.02.041","volume":"55","author":"Baraldi","year":"2014","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.ejmech.2015.03.018_bib19","first-page":"1203","volume":"1","author":"Lavanya","year":"2011","journal-title":"Int. J. Res. Pharm. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib20","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1021\/ol801399w","volume":"10","author":"Bridgwood","year":"2008","journal-title":"Org. Lett."},{"key":"10.1016\/j.ejmech.2015.03.018_bib21","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1080\/00397910802656091","volume":"39","author":"Sabitha","year":"2009","journal-title":"Synth. Commun."},{"key":"10.1016\/j.ejmech.2015.03.018_bib22","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.tetlet.2012.10.079","volume":"54","author":"Ghosh","year":"2013","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.ejmech.2015.03.018_bib23","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1080\/00397910802638560","volume":"39","author":"Raju","year":"2009","journal-title":"Synth. Commun."},{"key":"10.1016\/j.ejmech.2015.03.018_bib24","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1080\/00397911.2011.642923","volume":"43","author":"Shockravi","year":"2013","journal-title":"Synth. Commun."},{"key":"10.1016\/j.ejmech.2015.03.018_bib25","first-page":"o2247","volume":"E65","author":"Fun","year":"2009","journal-title":"Acta Crystallogr."},{"key":"10.1016\/j.ejmech.2015.03.018_bib26","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00706-002-0534-3","volume":"134","author":"Hashemi","year":"2003","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib27","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1021\/jm00255a010","volume":"27","author":"Loev","year":"1974","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib28","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1246\/bcsj.79.454","volume":"79","author":"Wang","year":"2006","journal-title":"Bull. Chem. Soc. Jpn."},{"key":"10.1016\/j.ejmech.2015.03.018_bib29","first-page":"112","volume":"11","author":"Osnaya","year":"2003","journal-title":"AKIVOC"},{"key":"10.1016\/j.ejmech.2015.03.018_bib30","first-page":"413","volume":"18","author":"Srinivas","year":"2009","journal-title":"Ind. J. Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib31","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1021\/jm9507993","volume":"39","author":"Naito","year":"1996","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib32","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1023\/A:1012365424900","volume":"66","author":"Arslan","year":"2001","journal-title":"Biochem. (Mosc)"},{"key":"10.1016\/j.ejmech.2015.03.018_bib33","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1248\/cpb.50.1443","volume":"50","author":"Khan","year":"2002","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2015.03.018_bib34","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1055\/s-2006-957410","volume":"64","author":"Dimas","year":"1998","journal-title":"Planta Med."},{"key":"10.1016\/j.ejmech.2015.03.018_bib35","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.steroids.2010.05.017","volume":"75","author":"Choudhary","year":"2010","journal-title":"Steroids"},{"key":"10.1016\/j.ejmech.2015.03.018_bib36","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1021\/bi00853a037","volume":"6","author":"Pocker","year":"1967","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2015.03.018_bib37","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0031-9422(03)00075-X","volume":"63","author":"Ahmad","year":"2003","journal-title":"Phytochemistry"},{"key":"10.1016\/j.ejmech.2015.03.018_bib38","doi-asserted-by":"crossref","first-page":"4286","DOI":"10.1016\/j.bmc.2011.05.052","volume":"19","author":"Khan","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2015.03.018_bib39","series-title":"GraFit Version 7.0","author":"Leatherbarrow","year":"2010"}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523415001853?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523415001853?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T21:13:55Z","timestamp":1566422035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523415001853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":39,"alternative-id":["S0223523415001853"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2015.03.018","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast \u03b1-glucosidase","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmech.2015.03.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}