{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:39:31Z","timestamp":1760549971697},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Department of Health Research (DHR), Indian Council of Medical Research, New Delhi, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"CSIR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004507","name":"CDRI","doi-asserted-by":"publisher","award":["GAP0155"],"award-info":[{"award-number":["GAP0155"]}],"id":[{"id":"10.13039\/501100004507","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.ejmech.2016.03.012","type":"journal-article","created":{"date-parts":[[2016,3,9]],"date-time":"2016-03-09T07:31:06Z","timestamp":1457508666000},"page":"275-290","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology"],"prefix":"10.1016","volume":"115","author":[{"given":"Nand","family":"Lal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santosh","family":"Jangir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veenu","family":"Bala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhanaraju","family":"Mandalapu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Sarswat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalit","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lokesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavana","family":"Kushwaha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atindra K.","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shagun","family":"Krishna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara","family":"Rawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen K.","family":"Shukla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagdamba P.","family":"Maikhuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad I.","family":"Siddiqi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopal","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishnu L.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2016.03.012_bib1","unstructured":"http:\/\/Cnls.Lanl.Gov\/\u223cRajan\/Aids-India\/Mywork\/Gupta_Hiv_India.Pdf (accessed on 20.05.14)."},{"key":"10.1016\/j.ejmech.2016.03.012_bib2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1136\/sti.2009.039362","article-title":"Trichomonas vaginalis: underdiagnosis in urban Australia could facilitate re-emergence","volume":"86","author":"Lusk","year":"2010","journal-title":"Sex. Transm. Infect."},{"key":"10.1016\/j.ejmech.2016.03.012_bib3","unstructured":"http:\/\/Www.Washingtontimes.Com\/News\/2010\/Nov\/22\/Us-Not-Close-to-Std-Goals-Cdc-Reports\/(accessed on 21.05.14)."},{"key":"10.1016\/j.ejmech.2016.03.012_bib4","unstructured":"http:\/\/Www.Nursingschools.Net\/Blog\/2010\/05\/10-Truly-Shocking-Stats-on-Stds-and-College-Students\/(accessed on 21.05.14)."},{"key":"10.1016\/j.ejmech.2016.03.012_bib5","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00436-010-1938-3","article-title":"Susceptibility invitro of clinically metronidazole resistant Trichomonas vaginalis to nitazoxanide, toyocamycin, and 2-fluoro-2'-deoxyadenosine","volume":"107","author":"Wright","year":"2010","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ejmech.2016.03.012_bib6","first-page":"318","article-title":"Mechanisms of resistance to azole antifungal compounds","volume":"1","author":"Marichal","year":"1999","journal-title":"Curr. Opin. Anti-Infect. Invest. Drugs"},{"key":"10.1016\/j.ejmech.2016.03.012_bib7","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1001\/jama.284.8.949","article-title":"Widely used spermicide may increase, not decrease, risk of HIV transmission","volume":"284","author":"Stephenson","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ejmech.2016.03.012_bib8","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1001\/jama.287.9.1117","article-title":"Effect of Nonoxynol-9 gel on urogenital gonorrhea and chlamydial infection: a randomized controlled trial","volume":"287","author":"Roddy","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.ejmech.2016.03.012_bib9","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0140-6736(02)11079-8","article-title":"Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial","volume":"360","author":"Van Damme","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ejmech.2016.03.012_bib10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1089\/152460901300039502","article-title":"Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: where have we been? where are we going?","volume":"10","author":"Elias","year":"2001","journal-title":"J.\u00a0Womens Health Gend. Based Med."},{"key":"10.1016\/j.ejmech.2016.03.012_bib11","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/sj.cr.7290340","article-title":"Trichomonas vaginalis perturbs the junctional complex in epithelial cells","volume":"15","author":"da Costa","year":"2005","journal-title":"Cell Res."},{"key":"10.1016\/j.ejmech.2016.03.012_bib12","unstructured":"http:\/\/www.nlm.nih.gov\/medlineplus\/trichomoniasis.html (accessed on 20.05.14)."},{"key":"10.1016\/j.ejmech.2016.03.012_bib13","first-page":"43","article-title":"Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies","volume":"68","author":"Coleman","year":"2013","journal-title":"ObstetGynecolSurv."},{"key":"10.1016\/j.ejmech.2016.03.012_bib14","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1258\/ijsa.2008.008067","article-title":"Genital tract infections among HIV-infected pregnant women in Malawi, Tanzania and Zambia","volume":"19","author":"Aboud","year":"2008","journal-title":"Int. J. STD AIDS"},{"key":"10.1016\/j.ejmech.2016.03.012_bib15","first-page":"30","article-title":"HIV\/vaginal candida coinfection: risk factors in women","volume":"2","author":"Umeh","year":"2010","journal-title":"J.\u00a0Microb. Antimicrob."},{"key":"10.1016\/j.ejmech.2016.03.012_bib16","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1439-0507.1998.tb00344.x","article-title":"In\u00a0vitro evaluation of voriconazole against clinical isolates of yeasts, molds and dermatophytes in comparison with itraconazole, ketoconazole, amphotericin B and griseofulvin","volume":"41","author":"Wildfeuer","year":"1998","journal-title":"Mycoses"},{"key":"10.1016\/j.ejmech.2016.03.012_bib17","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S1369-5274(98)80087-8","article-title":"Antifungals: mechanism of action and resistance, established and novel drugs","volume":"1","author":"Georgopapadakou","year":"1998","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.ejmech.2016.03.012_bib18","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.2174\/0929867306666220401183122","article-title":"Systemic antifungal agents against AIDS-related opportunistic infections: current status and emerging drugs in development","volume":"6","author":"Ablordeppey","year":"1999","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/QAI.0b013e31819907de","article-title":"Estimating HIV prevalence and risk behaviors among high-risk heterosexual men with multiple sex partners: use of respondent-driven sampling","volume":"51","author":"Chopra","year":"2009","journal-title":"J.\u00a0Acquir. Immune Defic. Syndr."},{"key":"10.1016\/j.ejmech.2016.03.012_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0166-6851(84)90096-3","article-title":"Thiol groups on the surface of anaerobic parasitic protozoa","volume":"13","author":"Gillin","year":"1984","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ejmech.2016.03.012_bib21","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1160\/TH09-11-0769","article-title":"Candida albicans and its metabolite gliotoxin inhibit platelet function via interaction with thiols","volume":"104","author":"Bertling","year":"2010","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.ejmech.2016.03.012_bib22","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S1472-6483(10)60435-X","article-title":"Free thiols in human spermatozoa:are Na+\/K+-ATPase, Ca2+-ATPase activities involved in sperm motility through peroxynitrite formation","volume":"18","author":"Vignini","year":"2009","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.ejmech.2016.03.012_bib23","doi-asserted-by":"crossref","first-page":"33485","DOI":"10.1074\/jbc.M109.054320","article-title":"The mercaptopyruvatesulphurtransferase of Trichomonasvaginalis links cysteine catabolism to the production of thioredoxinpersulfide","volume":"284","author":"Westrop","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib24","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1095\/biolreprod.108.067561","article-title":"Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility","volume":"79","author":"Nakamura","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ejmech.2016.03.012_bib25","doi-asserted-by":"crossref","first-page":"3357","DOI":"10.1016\/S0021-9258(18)93315-6","article-title":"Specific modification of protein sulfhydryl groups with alpha,beta-unsaturated compounds","volume":"243","author":"Cavins","year":"1968","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib26","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0223-5234(01)01292-2","article-title":"Substituted acrylophenones and related mannich bases as possible spermicides and inhibitors of HIV envelope glycoprotein-CD4 interaction","volume":"37","author":"Kumaria","year":"2002","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib27","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0010-7824(03)00022-2","article-title":"Mechanism of action of some acrylophenones, quinolines and dithiocarbamate as potent, non-detergent spermicidal agents","volume":"67","author":"Maikhuri","year":"2003","journal-title":"Contraception"},{"key":"10.1016\/j.ejmech.2016.03.012_bib28","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1124\/mol.108.053645","article-title":"The spermostatic and microbicidal actions of quinones and maleimides: toward a dual-purpose contraceptive agent","volume":"76","author":"Hughes","year":"2009","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejmech.2016.03.012_bib29","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.ejmech.2009.10.021","article-title":"Imidazole derivatives as possible microbicides with dual protection","volume":"45","author":"Kumar","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib30","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1016\/j.ejmech.2007.10.024","article-title":"Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides","volume":"43","author":"Kiran Kumar","year":"2008","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib31","doi-asserted-by":"crossref","first-page":"6642","DOI":"10.1016\/j.bmc.2007.08.024","article-title":"Synthesis of disulfide esters of dialkylaminocarbothioic acid as potent, non-detergent spermicidal agents","volume":"15","author":"Dwivedi","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib32","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1128\/AAC.00199-11","article-title":"Novel trichomonacidal spermicides","volume":"55","author":"Jain","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejmech.2016.03.012_bib33","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1002\/cmdc.201500291","article-title":"Innovative disulfide esters of dithiocarbamic acid as women-controlled contraceptive microbicides: a bioisosterism approach","volume":"10","author":"Mandalapu","year":"2015","journal-title":"Chemmedchem"},{"key":"10.1016\/j.ejmech.2016.03.012_bib34","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.ejmech.2015.07.021","article-title":"N-Alkyl\/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition","volume":"101","author":"Bala","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib35","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.bmcl.2014.12.062","article-title":"Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies","volume":"25","author":"Bala","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2016.03.012_bib36","doi-asserted-by":"crossref","first-page":"5782","DOI":"10.1016\/j.bmcl.2014.10.040","article-title":"Design and synthesis of substituted morpholin\/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential","volume":"24","author":"Bala","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2016.03.012_bib37","doi-asserted-by":"crossref","first-page":"7957","DOI":"10.1016\/S0040-4020(99)00386-5","article-title":"The chemistry of thiocyanic esters","volume":"55","author":"Erian","year":"1999","journal-title":"Tetrahedron"},{"key":"10.1016\/j.ejmech.2016.03.012_bib38","first-page":"1129","article-title":"Regioselective functionalization of glycerol with a dithiocarbamate moiety: an environmentally friendly route to safer fungicides","volume":"13","author":"De Sousa","year":"2011","journal-title":"GreenChem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib39","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1016\/j.ejmech.2008.10.032","article-title":"Parallel synthesis, molecular modelling and further structure\u2013activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors","volume":"44","author":"Spallarossa","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib40","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1021\/jm049252r","article-title":"Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives","volume":"48","author":"Ranise","year":"2005","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib41","unstructured":"http:\/\/emedicine.medscape.com\/article\/814525-overview (accessed on 06.05.14)."},{"key":"10.1016\/j.ejmech.2016.03.012_bib42","doi-asserted-by":"crossref","first-page":"7310","DOI":"10.1021\/jm901323s","article-title":"Bis (dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors","volume":"52","author":"Kapanda","year":"2009","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib43","unstructured":"http:\/\/services.mbi.ucla.edu\/SAVES."},{"key":"10.1016\/j.ejmech.2016.03.012_bib44","series-title":"Sybyl, Version 7.1","year":"2005"},{"key":"10.1016\/j.ejmech.2016.03.012_bib45","doi-asserted-by":"crossref","first-page":"25062","DOI":"10.1074\/jbc.M600688200","article-title":"Cysteine biosynthesis in Trichomonasvaginalis involves cysteine synthase utilizing O-phosphoserine","volume":"281","author":"Westrop","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib46a","article-title":"Carbodithioates and process for preparation thereof","author":"Sharma","year":"2014","journal-title":"Indian Pat. Appl."},{"key":"10.1016\/j.ejmech.2016.03.012_bib46b","article-title":"Preparation of carbodithioates with spermicidal activity","author":"Sharma","year":"2014","journal-title":"PCT Int. Appl."},{"key":"10.1016\/j.ejmech.2016.03.012_bib47","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0010-7824(98)00059-6","article-title":"Contraceptive testing of vaginal agents in rabbits","volume":"58","author":"Castle","year":"1998","journal-title":"Contraception"},{"key":"10.1016\/j.ejmech.2016.03.012_bib48","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ijantimicag.2015.10.022","article-title":"Ammonium salts of carbamodithioic acid as potent vaginal trichomonacides and fungicides","volume":"47","author":"Kushwaha","year":"2016","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ejmech.2016.03.012_bib49","doi-asserted-by":"crossref","first-page":"3090","DOI":"10.1039\/C4OB00005F","article-title":"A\u00a0unique dithiocarbamate chemistry during design & synthesis of novel sperm-immobilizing agents","volume":"12","author":"Jangir","year":"2014","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib50","doi-asserted-by":"crossref","first-page":"8620","DOI":"10.1021\/bi050485+","article-title":"Structure of the O-acetylserinesulfhydrylaseisoenzymeCysM from Escherichia coli","volume":"44","author":"Claus","year":"2005","journal-title":"Biochemistry"},{"key":"10.1016\/j.ejmech.2016.03.012_bib51","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1006\/jmbi.1993.1626","article-title":"Comparative protein modelling by satisfaction of spatial restraints","volume":"234","author":"\u0160ali","year":"1993","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.ejmech.2016.03.012_bib52","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J.\u00a0Comput. Chem."},{"key":"10.1016\/j.ejmech.2016.03.012_bib53","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF Chimera\u2014a visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J.\u00a0Comput. Chem."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523416301842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523416301842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T19:29:46Z","timestamp":1655234986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523416301842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":54,"alternative-id":["S0223523416301842"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2016.03.012","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmech.2016.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}