{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:22:54Z","timestamp":1790475774329,"version":"4.1.0"},"reference-count":270,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Hubei Natural Science Foundation of China","award":["2013CFC010"],"award-info":[{"award-number":["2013CFC010"]}]},{"name":"Campus Research Project of Hubei University of Science and Technology","award":["2016-19XB01"],"award-info":[{"award-number":["2016-19XB01"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.ejmech.2017.11.082","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T15:00:43Z","timestamp":1511967643000},"page":"710-723","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":186,"special_numbering":"C","title":["4-Quinolone derivatives and their activities against Gram positive pathogens"],"prefix":"10.1016","volume":"143","author":[{"given":"Gui-Fu","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baofeng","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-Shun","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmech.2017.11.082_bib1","first-page":"123","volume":"3","author":"Emami","year":"2005","journal-title":"Iran. J. Pharm. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ejmech.2017.09.050","volume":"141","author":"Hu","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib3","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1021\/cr030101q","volume":"105","author":"Mitscher","year":"2005","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ejmech.2017.11.082_bib4","doi-asserted-by":"crossref","first-page":"4874","DOI":"10.1021\/jm501881c","volume":"58","author":"Bisacchi","year":"2015","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib5","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cclet.2016.07.024","volume":"28","author":"Jia","year":"2017","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib6","series-title":"Guidelines for the Management of Drug-resistant Tuberculosis WHO\/TB\/96-210 (Rev.1)","author":"Crofton","year":"1997"},{"key":"10.1016\/j.ejmech.2017.11.082_bib7","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S1473-3099(03)00671-6","volume":"3","author":"Ginsburg","year":"2003","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ejmech.2017.11.082_bib8","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cclet.2016.07.032","volume":"28","author":"Xu","year":"2017","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ejmech.2017.04.002","volume":"133","author":"Hu","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib10","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ejmech.2017.05.004","volume":"136","author":"Hu","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib11","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ejmech.2017.06.051","volume":"138","author":"Zhang","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib12","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ejmech.2010.11.023","volume":"46","author":"Feng","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib13","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.1016\/j.ejmech.2010.04.027","volume":"45","author":"Feng","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib14","first-page":"61","volume":"28","author":"Feng","year":"2012","journal-title":"Chem. Res. Chin. Univ."},{"key":"10.1016\/j.ejmech.2017.11.082_bib15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ejmech.2017.05.057","volume":"138","author":"Xu","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib16","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ejmech.2012.07.010","volume":"55","author":"Feng","year":"2012","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib17","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.1016\/j.bmcl.2017.07.023","volume":"27","author":"Xu","year":"2017","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib18","unstructured":"Y. Q. Hu, L. D. Meng, M. Qiang, X. F. Song, J. Heterocycl. Chem. DOI information: 10.1002\/jhet.2933."},{"key":"10.1016\/j.ejmech.2017.11.082_bib19","doi-asserted-by":"crossref","first-page":"209","DOI":"10.14233\/ajchem.2014.15572","volume":"26","author":"Wang","year":"2014","journal-title":"Asian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib20","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00894-009-0549-3","volume":"16","author":"Koba","year":"2010","journal-title":"J.\u00a0Mol. Model"},{"key":"10.1016\/j.ejmech.2017.11.082_bib21","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1016\/S0960-894X(03)00208-7","volume":"13","author":"Kerns","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib22","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0002-9394(02)01334-X","volume":"133","author":"Mather","year":"2002","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.ejmech.2017.11.082_bib23","doi-asserted-by":"crossref","first-page":"14585","DOI":"10.1016\/S0021-9258(18)98726-0","volume":"266","author":"Robinson","year":"1991","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2011.00022","volume":"2","author":"Hern\u00e1ndez","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ejmech.2017.11.082_bib25","doi-asserted-by":"crossref","first-page":"4536","DOI":"10.1016\/j.bmcl.2005.07.005","volume":"15","author":"Foroumadi","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib26","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1021\/jm00400a017","volume":"31","author":"Domagala","year":"1988","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib27","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1021\/jm0510023","volume":"49","author":"Zhi","year":"2006","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib28","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1021\/jm0205090","volume":"46","author":"Kuramoto","year":"2003","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1021\/jm00105a020","volume":"34","author":"Ohta","year":"1991","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib30","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1021\/jm950558v","volume":"39","author":"Cecchetti","year":"1996","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib31","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1021\/jm960385p","volume":"40","author":"Cecchetti","year":"1997","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib32","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.ejmech.2013.07.021","volume":"68","author":"Garudachari","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib33","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1016\/S0960-894X(03)00399-8","volume":"13","author":"Gray","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib34","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1021\/jm701428b","volume":"51","author":"Asahina","year":"2008","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib35","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejmech.2015.09.030","volume":"104","author":"Zhang","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib36","doi-asserted-by":"crossref","first-page":"4727","DOI":"10.1021\/jm00103a011","volume":"35","author":"Segawa","year":"1992","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib37","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.3987\/COM-99-8712","volume":"51","author":"Matsuoka","year":"1999","journal-title":"Heterocycles"},{"key":"10.1016\/j.ejmech.2017.11.082_bib38","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1248\/cpb.47.1765","volume":"47","author":"Matsuoka","year":"1999","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib39","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1080\/00397911.2016.1271896","volume":"47","author":"El-Ziaty","year":"2017","journal-title":"Synth. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib40","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1248\/cpb.56.346","volume":"56","author":"Ikee","year":"2008","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib41","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.ejmech.2017.07.010","volume":"138","author":"Bueso-Bordis","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib42","doi-asserted-by":"crossref","first-page":"3194","DOI":"10.1021\/jm0402061","volume":"48","author":"Ahahina","year":"2005","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib43","doi-asserted-by":"crossref","first-page":"4693","DOI":"10.1021\/jm0497895","volume":"47","author":"Baker","year":"2004","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib44","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1021\/jm040204g","volume":"48","author":"Asanhina","year":"2005","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib45","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1002\/jhet.501","volume":"47","author":"Zheng","year":"2010","journal-title":"J.\u00a0Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib46","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00044-010-9509-9","volume":"21","author":"Zheng","year":"2012","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib47","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ejmech.2014.08.063","volume":"86","author":"Cui","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib48","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1016\/j.bmcl.2013.03.118","volume":"23","author":"Cui","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib49","doi-asserted-by":"crossref","first-page":"609","DOI":"10.13005\/ojc\/290231","volume":"29","author":"Abdullah","year":"2013","journal-title":"Orient. J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib50","doi-asserted-by":"crossref","first-page":"9635","DOI":"10.1016\/S0040-4020(01)00964-4","volume":"57","author":"Michael","year":"2001","journal-title":"Tetrahedron"},{"key":"10.1016\/j.ejmech.2017.11.082_bib51","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1023\/A:1015189626030","volume":"35","author":"Nosova","year":"2001","journal-title":"Pharm. Chem. J."},{"key":"10.1016\/j.ejmech.2017.11.082_bib52","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/jhet.5570370213","volume":"37","author":"Miao","year":"2000","journal-title":"J.\u00a0Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib53","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.ejmech.2008.07.024","volume":"44","author":"Reddy","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib54","doi-asserted-by":"crossref","first-page":"637","DOI":"10.2174\/157017811799304322","volume":"8","author":"Chepyala","year":"2011","journal-title":"Lett. Org. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib55","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.bmcl.2005.11.065","volume":"16","author":"Wiles","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib56","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1021\/jm101604v","volume":"54","author":"Kim","year":"2011","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib57","unstructured":"F. Samrin, A. Sharma, I. A. Khan, S. Puri, 49 (2012) 1391\u20131397."},{"key":"10.1016\/j.ejmech.2017.11.082_bib58","first-page":"969","volume":"51B","author":"Lingaiah","year":"2012","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib59","first-page":"530","volume":"40B","author":"Khan","year":"2001","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib60","first-page":"880","volume":"51B","author":"Patel","year":"2012","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib61","first-page":"1548","volume":"43B","author":"Danish","year":"2004","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib62","first-page":"1496","volume":"50B","author":"Kumar","year":"2011","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib63","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0014-827X(01)01112-0","volume":"56","author":"Jung","year":"2001","journal-title":"IL Farm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib64","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/jhet.5570380109","volume":"38","author":"Jung","year":"2001","journal-title":"J.\u00a0Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib65","doi-asserted-by":"crossref","first-page":"5722","DOI":"10.1021\/jm200370y","volume":"54","author":"Sabatini","year":"2011","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib66","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.bmcl.2012.12.045","volume":"23","author":"Li","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib67","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.ejmech.2013.08.050","volume":"69","author":"Kahriman","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib68","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/jhet.800","volume":"49","author":"Kahriman","year":"2012","journal-title":"J.\u00a0Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib69","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2174\/157340610791321442","volume":"6","author":"Bartzatt","year":"2010","journal-title":"Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib70","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.2174\/092986707781058805","volume":"14","author":"Viegas-Junior","year":"2007","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib71","doi-asserted-by":"crossref","first-page":"486","DOI":"10.2174\/1389557517666161111110121","volume":"17","author":"Matias","year":"2017","journal-title":"Mini-Rev. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib72","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/jac\/31.1.81","volume":"31","author":"Pfaller","year":"1993","journal-title":"J.\u00a0Antimicrob. Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib73","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nrd2202","volume":"6","author":"Silver","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ejmech.2017.11.082_bib74","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ejmech.2016.08.031","volume":"124","author":"Kant","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib75","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1007\/s00044-011-9655-8","volume":"21","author":"Jubie","year":"2012","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib76","doi-asserted-by":"crossref","first-page":"7954","DOI":"10.1021\/jm901357n","volume":"52","author":"Dubar","year":"2009","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib77","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1021\/jm100117e","volume":"53","author":"Bellot","year":"2010","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib78","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1039\/c0md00082e","volume":"1","author":"Matos","year":"2010","journal-title":"Med. Chem. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib79","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.molstruc.2010.01.036","volume":"969","author":"Sultana","year":"2010","journal-title":"J.\u00a0Mol. Struct."},{"key":"10.1016\/j.ejmech.2017.11.082_bib80","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.inoche.2011.10.037","volume":"15","author":"Patel","year":"2015","journal-title":"Inorg. Chem. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib81","first-page":"622","volume":"59","author":"Patel","year":"2012","journal-title":"Acta Chim. Slov."},{"key":"10.1016\/j.ejmech.2017.11.082_bib82","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.inoche.2012.10.018","volume":"27","author":"Patel","year":"2013","journal-title":"Inorg. Chem. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib83","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jinorgbio.2016.02.026","volume":"162","author":"Mjos","year":"2016","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib84","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.saa.2012.05.037","volume":"97","author":"Patel","year":"2012","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.ejmech.2017.11.082_bib85","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ejmech.2014.08.043","volume":"86","author":"Protogeraki","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib86","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.saa.2010.11.056","volume":"78","author":"Patel","year":"2011","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.ejmech.2017.11.082_bib87","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jinorgbio.2012.12.013","volume":"121","author":"Zampakou","year":"2013","journal-title":"J.\u00a0Inorg. Biochem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib88","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/s00044-016-1503-4","volume":"25","author":"Gajera","year":"2016","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib89","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00706-013-1086-4","volume":"145","author":"Patel","year":"2014","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib90","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/j.saa.2006.12.078","volume":"68","author":"Refat","year":"2007","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.ejmech.2017.11.082_bib91","first-page":"574","volume":"57","author":"Sadeek","year":"2013","journal-title":"Chem. Soc."},{"key":"10.1016\/j.ejmech.2017.11.082_bib92","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1007\/s00044-012-0132-9","volume":"22","author":"Sultana","year":"2013","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib93","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.saa.2011.07.072","volume":"82","author":"El-Gamel","year":"2011","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.ejmech.2017.11.082_bib94","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.saa.2012.11.045","volume":"104","author":"Patel","year":"2013","journal-title":"Spectrochim. Acta Part A"},{"key":"10.1016\/j.ejmech.2017.11.082_bib95","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.molstruc.2011.09.009","volume":"1006","author":"Sadeek","year":"2011","journal-title":"J.\u00a0Mol. Struct."},{"key":"10.1016\/j.ejmech.2017.11.082_bib96","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.cclet.2012.01.029","volume":"23","author":"Hu","year":"2012","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib97","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.ejmech.2013.06.056","volume":"67","author":"Srivastava","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib98","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.ejmech.2017.07.004","volume":"138","author":"Abdelrahman","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib99","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s00044-016-1544-8","volume":"25","author":"Allaka","year":"2016","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib100","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1155\/2012\/340451","volume":"9","author":"Jubie","year":"2012","journal-title":"E-J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib101","doi-asserted-by":"crossref","first-page":"4488","DOI":"10.1021\/acs.jmedchem.5b01678","volume":"59","author":"Cui","year":"2016","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib102","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1007\/s00044-011-9728-8","volume":"21","author":"Patel","year":"2012","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib103","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s00706-010-0263-y","volume":"141","author":"Figueroa-Valverde","year":"2010","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib104","first-page":"1237","volume":"57","author":"Chattha","year":"2012","journal-title":"Chem. Soc."},{"key":"10.1016\/j.ejmech.2017.11.082_bib105","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1248\/cpb.c13-00797","volume":"62","author":"Rajulu","year":"2014","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib106","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1007\/s00044-010-9443-x","volume":"20","author":"Patel","year":"2011","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib107","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s00044-012-0020-3","volume":"22","author":"Lingaiah","year":"2013","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib108","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1007\/s12272-010-1203-4","volume":"33","author":"Arayne","year":"2010","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib109","first-page":"126","volume":"46B","author":"Patel","year":"2007","journal-title":"Indian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib110","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.ejmech.2016.10.011","volume":"124","author":"Cheng","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib111","doi-asserted-by":"crossref","first-page":"6025","DOI":"10.1016\/j.ejmech.2011.10.014","volume":"46","author":"Az\u00e9ma","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib112","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S0960-894X(03)00093-3","volume":"13","author":"Jarvest","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib113","doi-asserted-by":"crossref","first-page":"5961","DOI":"10.1016\/j.bmcl.2011.07.060","volume":"21","author":"Nguyen","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib114","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.3762\/bjoc.9.176","volume":"9","author":"Li","year":"2013","journal-title":"Beilstein J. Org. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib115","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1021\/jm00079a028","volume":"35","author":"Ledoussal","year":"1992","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib116","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1128\/AAC.44.12.3351-3356.2000","volume":"44","author":"Fung-Tomc","year":"2000","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib117","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1128\/AAC.43.5.1077","volume":"43","author":"Takahata","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib118","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1358\/dof.1999.024.12.561767","volume":"24","author":"Graul","year":"1999","journal-title":"Drug Fut."},{"key":"10.1016\/j.ejmech.2017.11.082_bib119","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.farmac.2004.01.014","volume":"59","author":"Sbardella","year":"2004","journal-title":"Il Farm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib120","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11030-016-9695-6","volume":"21","author":"Arasakumar","year":"2017","journal-title":"Mol. Divers."},{"key":"10.1016\/j.ejmech.2017.11.082_bib121","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF02464218","volume":"32","author":"Glushkov","year":"1998","journal-title":"Pharm. Chem. J."},{"key":"10.1016\/j.ejmech.2017.11.082_bib122","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ejmech.2016.09.022","volume":"125","author":"Pavlovi\u0107","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib123","doi-asserted-by":"crossref","first-page":"4952","DOI":"10.1021\/jm960414w","volume":"39","author":"Cecchetti","year":"1996","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib124","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1248\/cpb.43.2123","volume":"43","author":"Fujita","year":"1995","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib125","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1248\/cpb.44.987","volume":"44","author":"Fujita","year":"1996","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib126","doi-asserted-by":"crossref","first-page":"3244","DOI":"10.1016\/j.bmcl.2010.04.062","volume":"20","author":"Hutinec","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib127","doi-asserted-by":"crossref","first-page":"6559","DOI":"10.1016\/j.bmc.2010.06.049","volume":"18","author":"Fajdeti\u0107","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib128","doi-asserted-by":"crossref","first-page":"6569","DOI":"10.1016\/j.bmc.2010.06.048","volume":"18","author":"Kapi\u0107","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib129","doi-asserted-by":"crossref","first-page":"7270","DOI":"10.1016\/j.bmc.2011.07.011","volume":"19","author":"Kapi\u0107","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib130","doi-asserted-by":"crossref","first-page":"7281","DOI":"10.1016\/j.bmc.2011.07.010","volume":"19","author":"Kapi\u0107","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib131","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1021\/ml100253p","volume":"2","author":"Pavlovi\u0107","year":"2011","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib132","doi-asserted-by":"crossref","first-page":"8566","DOI":"10.1016\/j.bmc.2010.10.024","volume":"18","author":"Pavlovi\u0107","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib133","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.bmc.2016.01.055","volume":"24","author":"Pavlovi\u0107","year":"2016","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib134","doi-asserted-by":"crossref","first-page":"6547","DOI":"10.1016\/j.bmc.2010.06.050","volume":"18","author":"\u0160kugor","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib135","doi-asserted-by":"crossref","first-page":"6578","DOI":"10.1016\/j.bmc.2010.07.007","volume":"18","author":"Jakopovi\u0107","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib136","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.14233\/ajchem.2014.15949","volume":"26","author":"Zhang","year":"2014","journal-title":"Asian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib137","doi-asserted-by":"crossref","first-page":"5214","DOI":"10.1128\/AAC.01054-10","volume":"54","author":"Malik","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib138","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.bmcl.2007.01.090","volume":"17","author":"Murphy","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib139","doi-asserted-by":"crossref","first-page":"5193","DOI":"10.1016\/j.bmcl.2004.07.064","volume":"14","author":"Inagaki","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib140","doi-asserted-by":"crossref","first-page":"6879","DOI":"10.1016\/j.bmc.2009.08.026","volume":"17","author":"Miyauchi","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib141","doi-asserted-by":"crossref","first-page":"5195","DOI":"10.1016\/j.bmcl.2010.07.006","volume":"20","author":"Chai","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib142","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1016\/j.bmcl.2006.03.103","volume":"16","author":"Foroumadi","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib143","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.ejmech.2006.12.034","volume":"42","author":"Foroumadi","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib144","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1021\/jm0100335","volume":"44","author":"Chen","year":"2001","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib145","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1021\/jm000153x","volume":"43","author":"Fang","year":"2000","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib146","doi-asserted-by":"crossref","first-page":"5498","DOI":"10.1016\/j.ejmech.2010.08.050","volume":"45","author":"Qiang","year":"2010","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib147","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/ardp.200900191","volume":"343","author":"Zhang","year":"2010","journal-title":"Arch. Pharm. Chem. Life Sci."},{"key":"10.1016\/j.ejmech.2017.11.082_bib148","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.1016\/j.bmcl.2011.04.002","volume":"21","author":"Chai","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib149","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1016\/j.bmcl.2016.03.050","volume":"26","author":"Huang","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib150","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1002\/cmdc.201200210","volume":"7","author":"Lv","year":"2012","journal-title":"ChemmedChem"},{"key":"10.1016\/j.ejmech.2017.11.082_bib151","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cclet.2009.07.011","volume":"21","author":"Wang","year":"2010","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib152","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.ejmech.2014.09.029","volume":"86","author":"Liu","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib153","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1016\/j.ejmech.2011.06.032","volume":"46","author":"Chai","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib154","doi-asserted-by":"crossref","first-page":"6822","DOI":"10.3390\/molecules19056822","volume":"19","author":"Zhang","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib155","doi-asserted-by":"crossref","first-page":"3872","DOI":"10.3390\/molecules18043872","volume":"18","author":"Wei","year":"2013","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib156","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.3390\/molecules16032626","volume":"16","author":"Guo","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib157","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.bmcl.2010.12.073","volume":"21","author":"Zhang","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib158","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1016\/j.bmcl.2013.01.048","volume":"23","author":"Lv","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib159","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1016\/j.ejmech.2009.04.041","volume":"44","author":"Chai","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib160","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1016\/j.ejmech.2011.03.026","volume":"46","author":"Wang","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib161","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.14233\/ajchem.2014.15943","volume":"26","author":"Feng","year":"2014","journal-title":"Asian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib162","doi-asserted-by":"crossref","first-page":"8264","DOI":"10.1016\/j.tet.2011.08.089","volume":"67","author":"Feng","year":"2011","journal-title":"Tetrahedron"},{"key":"10.1016\/j.ejmech.2017.11.082_bib163","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ejmech.2012.07.010","volume":"55","author":"Feng","year":"2012","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib164","doi-asserted-by":"crossref","first-page":"5058","DOI":"10.1016\/j.bmcl.2015.10.027","volume":"25","author":"Huang","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib165","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2174\/138955706776361493","volume":"6","author":"Emami","year":"2006","journal-title":"Mini. Rev. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib166","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1128\/AAC.01649-07","volume":"52","author":"Robertson","year":"2008","journal-title":"Antimcob. Agents. Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib167","doi-asserted-by":"crossref","first-page":"6645","DOI":"10.1021\/acs.jmedchem.6b00485","volume":"59","author":"Ma","year":"2016","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib168","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijantimicag.2014.03.016","volume":"44","author":"Rashid","year":"2014","journal-title":"Int. J. Antimicro. Agents"},{"key":"10.1016\/j.ejmech.2017.11.082_bib169","first-page":"216","volume":"28","author":"Rashid","year":"2014","journal-title":"Clin. Microb."},{"key":"10.1016\/j.ejmech.2017.11.082_bib170","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1016\/S0968-0896(03)00083-X","volume":"11","author":"Hubschwerlen","year":"2003","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib171","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.1016\/j.bmcl.2003.07.021","volume":"13","author":"Gordeev","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib172","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1128\/AAC.01311-05","volume":"51","author":"Butler","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib173","doi-asserted-by":"crossref","first-page":"5865","DOI":"10.1016\/j.bmc.2004.08.028","volume":"12","author":"Sriram","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib174","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0223-5234(00)00125-2","volume":"35","author":"Pandeya","year":"2000","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib175","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00044-005-0135-x","volume":"14","author":"Sriram","year":"2005","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib176","first-page":"103","volume":"67","author":"Pandeya","year":"1999","journal-title":"Sci. Pharm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib177","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.farmac.2005.03.005","volume":"60","author":"Sriram","year":"2005","journal-title":"Il Farm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib178","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1016\/S0960-894X(03)00376-7","volume":"13","author":"Kerns","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib179","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1016\/j.bmcl.2016.03.062","volume":"26","author":"Panda","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib180","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ejmech.2015.04.058","volume":"97","author":"Plech","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib181","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ejmech.2012.11.040","volume":"60","author":"Plech","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib182","doi-asserted-by":"crossref","first-page":"444","DOI":"10.2174\/1570180813666161024165613","volume":"14","author":"Demirci","year":"2017","journal-title":"Lett. Drug Des. Discov."},{"key":"10.1016\/j.ejmech.2017.11.082_bib183","doi-asserted-by":"crossref","first-page":"5363","DOI":"10.1016\/j.bmcl.2012.07.064","volume":"22","author":"Wang","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib184","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0014-827X(03)00191-5","volume":"58","author":"Foroumadi","year":"2003","journal-title":"Il Farm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib185","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1016\/j.bmcl.2009.01.007","volume":"19","author":"Md-Saleh","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib186","doi-asserted-by":"crossref","first-page":"4466","DOI":"10.1021\/jm1003304","volume":"53","author":"Pieroni","year":"2010","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib187","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1016\/j.bmcl.2012.02.019","volume":"22","author":"Karoli","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib188","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1016\/j.bmc.2005.12.058","volume":"14","author":"Formoumadi","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib189","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1248\/cpb.55.894","volume":"55","author":"Letafat","year":"2007","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib190","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1211\/146080800128736196","volume":"6","author":"Mirzaei","year":"2000","journal-title":"Pharm. Pharmacol. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib191","doi-asserted-by":"crossref","first-page":"3899","DOI":"10.1021\/jm990015b","volume":"42","author":"Jung","year":"1999","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib192","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1021\/jm900028n","volume":"52","author":"Pokrovskaya","year":"2009","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib193","doi-asserted-by":"crossref","first-page":"6955","DOI":"10.1021\/jm801007z","volume":"51","author":"Houghton","year":"2008","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib194","doi-asserted-by":"crossref","first-page":"9217","DOI":"10.1016\/j.bmc.2008.09.010","volume":"16","author":"Tanaka","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib195","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.ejmech.2011.10.049","volume":"47","author":"McPherson III","year":"2012","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib196","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1021\/jm0105326","volume":"45","author":"Herczegh","year":"2002","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib197","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1021\/acs.jmedchem.6b01615","volume":"60","author":"Sedghizadeh","year":"2017","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib198","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1021\/ml300150y","volume":"3","author":"Ju\u00e1rez-Hern\u00e1ndez","year":"2012","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib199","first-page":"551","volume":"65","author":"Sharma","year":"2008","journal-title":"Acta. Pol. Pharm."},{"key":"10.1016\/j.ejmech.2017.11.082_bib200","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1128\/AAC.47.11.3435-3441.2003","volume":"47","author":"Roseeuw","year":"2003","journal-title":"Antimicrob. Agents. Chemother."},{"key":"10.1016\/j.ejmech.2017.11.082_bib201","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1016\/j.bmcl.2014.01.065","volume":"24","author":"Ibrahim","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib202","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ardp.200600169","volume":"340","author":"Foroumadi","year":"2007","journal-title":"Arch. Pharm. Chem. Life. Sci."},{"key":"10.1016\/j.ejmech.2017.11.082_bib203","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1211\/146080899128734181","volume":"5","author":"Foroumadi","year":"1999","journal-title":"Pharm. Pharmacol. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib204","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/ardp.200700090","volume":"341","author":"Emami","year":"2008","journal-title":"Arch. Pharm. Chem. Life. Sci."},{"key":"10.1016\/j.ejmech.2017.11.082_bib205","first-page":"4363","volume":"22","author":"Deepika","year":"2010","journal-title":"Asian J. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib206","doi-asserted-by":"crossref","first-page":"5487","DOI":"10.1016\/j.ejmech.2011.09.011","volume":"46","author":"Abdel-Aziz","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib207","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1021\/bc300610f","volume":"24","author":"Wencewicz","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib208","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.1039\/c3ob40162f","volume":"21","author":"Milner","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib209","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.bmc.2012.10.028","volume":"21","author":"Souto","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib210","doi-asserted-by":"crossref","first-page":"4044","DOI":"10.1021\/jm400265k","volume":"56","author":"Wencewicaz","year":"2013","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib211","doi-asserted-by":"crossref","first-page":"3620","DOI":"10.1016\/j.bmc.2014.05.018","volume":"22","author":"Wang","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib212","doi-asserted-by":"crossref","first-page":"4049","DOI":"10.1016\/j.bmc.2014.05.067","volume":"22","author":"Fardeau","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib213","doi-asserted-by":"crossref","first-page":"4561","DOI":"10.1016\/j.bmc.2015.06.009","volume":"23","author":"Vembu","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib214","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1016\/j.bmc.2017.02.068","volume":"25","author":"Shavit","year":"2017","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib215","doi-asserted-by":"crossref","first-page":"6513","DOI":"10.1016\/j.bmcl.2012.05.026","volume":"22","author":"Cormier","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib216","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.bmcl.2015.11.063","volume":"26","author":"Venepally","year":"2016","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib217","doi-asserted-by":"crossref","first-page":"483","DOI":"10.5012\/bkcs.2011.32.2.483","volume":"32","author":"Sultana","year":"2011","journal-title":"Bull. Korean Chem. Soc."},{"key":"10.1016\/j.ejmech.2017.11.082_bib218","doi-asserted-by":"crossref","first-page":"4726","DOI":"10.1016\/j.ejmech.2009.05.028","volume":"44","author":"Yu","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib219","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ejmech.2013.10.055","volume":"71","author":"Suresh","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib220","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1007\/s00044-009-9264-y","volume":"19","author":"Sultana","year":"2010","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib221","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1007\/s00044-013-0699-9","volume":"23","author":"Arayne","year":"2014","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib222","doi-asserted-by":"crossref","first-page":"7557","DOI":"10.3390\/molecules18077557","volume":"18","author":"Chen","year":"2013","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib223","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1016\/j.bmcl.2015.06.041","volume":"25","author":"Zhang","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib224","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/cbdd.12395","volume":"85","author":"Li","year":"2015","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.ejmech.2017.11.082_bib225","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ejmech.2016.01.052","volume":"111","author":"Zhang","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib226","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1515\/hc-2012-0082","volume":"18","author":"Guruswamy","year":"2012","journal-title":"Heterocycl. Commun."},{"key":"10.1016\/j.ejmech.2017.11.082_bib227","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.cclet.2010.06.011","volume":"21","author":"Guo","year":"2010","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib228","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.ejmech.2013.05.003","volume":"65","author":"Jardosh","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib229","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ejmech.2013.07.032","volume":"68","author":"Emami","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib230","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejmech.2016.03.086","volume":"116","author":"Chugunova","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib231","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.ijantimicag.2009.11.022","volume":"35","author":"Wainwright","year":"2010","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ejmech.2017.11.082_bib232","doi-asserted-by":"crossref","first-page":"857","DOI":"10.7164\/antibiotics.51.857","volume":"51","author":"Hershberger","year":"1998","journal-title":"J.\u00a0Antibiot."},{"key":"10.1016\/j.ejmech.2017.11.082_bib233","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/14756366.2011.611943","volume":"28","author":"Sharma","year":"2013","journal-title":"J.\u00a0Enzym. Inhib. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib234","unstructured":"H. K. Gen\u00e7er, S. Levent, U. A. \u00c7evik, Y. \u00d6zkay, S. Iljin, Bioorg. Med. Chem. Lett. 1162\u20131168."},{"key":"10.1016\/j.ejmech.2017.11.082_bib235","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.ejmech.2017.05.064","volume":"137","author":"El-Gohary","year":"2017","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib236","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jfluchem.2011.02.002","volume":"132","author":"Darehkordi","year":"2011","journal-title":"J.\u00a0Fluor. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib237","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00044-016-1526-x","volume":"25","author":"Pandit","year":"2016","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib238","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1007\/s007060070029","volume":"131","author":"Kidwai","year":"2000","journal-title":"Monatsh. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib239","first-page":"432","volume":"58","author":"Foroumadi","year":"2003","journal-title":"Pharmazie"},{"key":"10.1016\/j.ejmech.2017.11.082_bib240","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ejmech.2006.03.027","volume":"41","author":"Talath","year":"2006","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib241","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1016\/j.ejmech.2011.04.035","volume":"46","author":"Kumar","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib242","doi-asserted-by":"crossref","first-page":"8288","DOI":"10.1039\/c1ob06250f","volume":"24","author":"No\u00ebl","year":"2011","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib243","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1021\/jm025502x","volume":"45","author":"Jarvest","year":"2002","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib244","author":"Xu","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib245","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1016\/j.bmcl.2015.07.010","volume":"25","author":"Ross","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib246","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/BF02464368","volume":"31","author":"Fedorova","year":"1997","journal-title":"Pharm. Chem. J."},{"key":"10.1016\/j.ejmech.2017.11.082_bib247","doi-asserted-by":"crossref","first-page":"3816","DOI":"10.1016\/j.bmcl.2015.07.077","volume":"25","author":"Panda","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib248","doi-asserted-by":"crossref","first-page":"7274","DOI":"10.1016\/j.bmc.2007.08.031","volume":"15","author":"Zhang","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib249","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1021\/jm060844e","volume":"50","author":"Wang","year":"2007","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib250","doi-asserted-by":"crossref","first-page":"3928","DOI":"10.1016\/j.bmcl.2015.07.044","volume":"25","author":"Huang","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib251","doi-asserted-by":"crossref","first-page":"5232","DOI":"10.1021\/jm050035f","volume":"48","author":"de Souza","year":"2005","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib252","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.ejmech.2014.08.065","volume":"86","author":"Al-Trawneh","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib253","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1007\/s00044-011-9692-3","volume":"21","author":"AL-Hiari","year":"2012","journal-title":"Med. Chem. Res."},{"key":"10.1016\/j.ejmech.2017.11.082_bib254","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1021\/jm030272n","volume":"46","author":"Hu","year":"2003","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib255","doi-asserted-by":"crossref","first-page":"5971","DOI":"10.1016\/j.bmcl.2012.07.040","volume":"22","author":"Wang","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib256","doi-asserted-by":"crossref","first-page":"7688","DOI":"10.1016\/j.bmcl.2012.09.106","volume":"22","author":"Qi","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib257","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/cbdd.12299","volume":"84","author":"Patel","year":"2014","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.ejmech.2017.11.082_bib258","doi-asserted-by":"crossref","first-page":"4933","DOI":"10.1016\/j.bmcl.2009.07.087","volume":"19","author":"Zhu","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib259","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1086\/314061","volume":"31","author":"Grasela","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ejmech.2017.11.082_bib260","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1248\/cpb.48.1667","volume":"48","author":"Kawakami","year":"2000","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejmech.2017.11.082_bib261","first-page":"3344","volume":"36","author":"Kimura","year":"1993","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib262","doi-asserted-by":"crossref","first-page":"4745","DOI":"10.1021\/jm00103a013","volume":"35","author":"Suto","year":"1992","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib263","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.bmcl.2003.12.044","volume":"14","author":"Choi","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ejmech.2017.11.082_bib264","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/S0968-0896(99)00207-2","volume":"7","author":"Cecchetti","year":"1999","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib265","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1021\/jm00186a014","volume":"23","author":"Koga","year":"1980","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib266","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.3987\/COM-11-12274","volume":"83","author":"Zahra","year":"2011","journal-title":"Heterocycles"},{"key":"10.1016\/j.ejmech.2017.11.082_bib267","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.3390\/12061240","volume":"12","author":"Al-Hiari","year":"2007","journal-title":"Molecules"},{"key":"10.1016\/j.ejmech.2017.11.082_bib268","doi-asserted-by":"crossref","first-page":"422","DOI":"10.2174\/1570178611666140401220850","volume":"11","author":"Sweidan","year":"2014","journal-title":"Lett. Org. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib269","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/jhet.812","volume":"49","author":"Reddy","year":"2012","journal-title":"J.\u00a0Heterocycl. Chem."},{"key":"10.1016\/j.ejmech.2017.11.082_bib270","doi-asserted-by":"crossref","first-page":"649","DOI":"10.3109\/14756366.2010.543421","volume":"26","author":"Al-Hiari","year":"2011","journal-title":"J.\u00a0Enzym. Inhib. Med. Chem."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523417309856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0223523417309856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T16:48:17Z","timestamp":1660063697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0223523417309856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":270,"alternative-id":["S0223523417309856"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2017.11.082","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"4-Quinolone derivatives and their activities against Gram positive pathogens","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmech.2017.11.082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}