{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:42:57Z","timestamp":1790541777026,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundations of China","doi-asserted-by":"crossref","award":["21171079"],"award-info":[{"award-number":["21171079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100010871","name":"the Recruitment Program of Global Experts","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010871","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medicinal Chemistry"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.ejmech.2019.05.017","type":"journal-article","created":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T11:14:33Z","timestamp":1557573273000},"page":"456-475","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Toxicity, bioactivity, release of H2S in\u00a0vivo and pharmaco-kinetics of H2S-donors with thiophosphamide structure"],"prefix":"10.1016","volume":"176","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7990-6184","authenticated-orcid":false,"given":"Jinlong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanni","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jili","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongjie","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dian","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4134-1779","authenticated-orcid":false,"given":"Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingke","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonglin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.ejmech.2019.05.017_bib1","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two's company, three\u2019sa crowd: can H2S be the third endogenous gaseous transmitter?","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.ejmech.2019.05.017_bib2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00109-012-0873-4","article-title":"Hydrogen sulfide: a gasotransmitter of clinical relevance","volume":"90","author":"Vandiver","year":"2012","journal-title":"J.\u00a0Mol. Med."},{"issue":"4","key":"10.1016\/j.ejmech.2019.05.017_bib3","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1021\/tx2005234","article-title":"Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species","volume":"25","author":"Fukuto","year":"2012","journal-title":"Chem. Res. Toxicol."},{"issue":"2","key":"10.1016\/j.ejmech.2019.05.017_bib4","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.resp.2012.04.004","article-title":"Evolutionary and comparative aspects of nitric oxide, carbon monoxide and hydrogen sulfide","volume":"184","author":"Olson","year":"2012","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"2","key":"10.1016\/j.ejmech.2019.05.017_bib5","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ejmech.2019.05.017_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.phrs.2018.03.002","article-title":"Hydrogen sulfide and autophagy: a double edged sword","volume":"131","author":"Wu","year":"2018","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.ejmech.2019.05.017_bib7","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1474-9726.2009.00543.x","article-title":"Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models","volume":"9","author":"Hu","year":"2010","journal-title":"Aging Cell"},{"issue":"5","key":"10.1016\/j.ejmech.2019.05.017_bib8","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.freeradbiomed.2006.12.011","article-title":"Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative","volume":"42","author":"Li","year":"2007","journal-title":"Free Radic. Biol. Med."},{"issue":"11","key":"10.1016\/j.ejmech.2019.05.017_bib9","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1042\/CS20110267","article-title":"Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools","volume":"121","author":"Whiteman","year":"2011","journal-title":"Clin. Sci."},{"issue":"3","key":"10.1016\/j.ejmech.2019.05.017_bib10","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.pharep.2015.01.005","article-title":"Hydrogen sulfide in pharmacology and medicine\u2013An update","volume":"67","author":"Be\u0142towski","year":"2015","journal-title":"Pharmacol. Rep."},{"issue":"2","key":"10.1016\/j.ejmech.2019.05.017_bib11","doi-asserted-by":"crossref","first-page":"483. e1","DOI":"10.1016\/j.urology.2011.10.013","article-title":"Characterization of hydrogen sulfide and its synthases, cystathionine \u03b2-synthase and cystathionine \u03b3-lyase, in human prostatic tissue and cells","volume":"79","author":"Guo","year":"2012","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00726-010-0510-x","article-title":"Hydrogen sulfide: its production, release and functions","volume":"41","author":"Kimura","year":"2011","journal-title":"Amino Acids"},{"issue":"5","key":"10.1016\/j.ejmech.2019.05.017_bib13","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/jb\/mvp111","article-title":"Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide","volume":"146","author":"Shibuya","year":"2009","journal-title":"J.\u00a0Biochem."},{"issue":"6","key":"10.1016\/j.ejmech.2019.05.017_bib14","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1128\/MCB.01215-12","article-title":"Hydrogen sulfide, the next potent preventive and therapeutic agent in aging and age-associated diseases","volume":"33","author":"Zhang","year":"2013","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.ejmech.2019.05.017_bib15","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1038\/ncomms2371","article-title":"A\u00a0novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells","volume":"4","author":"Shibuya","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ejmech.2019.05.017_bib16","article-title":"The cardioprotective effects of hydrogen sulfide in heart diseases: from molecular mechanisms to therapeutic potential","volume":"13","author":"Shen","year":"2015","journal-title":"Oxidative medicine and cellular longevity"},{"key":"10.1016\/j.ejmech.2019.05.017_bib17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pharmthera.2015.04.004","article-title":"Hydrogen sulfide and cardioprotection\u2014mechanistic insights and clinical translatability","volume":"152","author":"Salloum","year":"2015","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ejmech.2019.05.017_bib18","first-page":"1","article-title":"Role of hydrogen sulfide in cerebrovascular alteration during aging","author":"Mun","year":"2019","journal-title":"Arch Pharm. Res. (Seoul)"},{"issue":"2","key":"10.1016\/j.ejmech.2019.05.017_bib19","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00380-003-0743-7","article-title":"The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells","volume":"19","author":"Du","year":"2004","journal-title":"Heart Vessel."},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib20","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.neures.2009.09.1713","article-title":"Hydrogen sulfide regulates intracellular pH in rat primary cultured glia cells","volume":"66","author":"Lu","year":"2010","journal-title":"Neurosci. Res."},{"issue":"5","key":"10.1016\/j.ejmech.2019.05.017_bib21","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrd4433","article-title":"Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter","volume":"14","author":"Wallace","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ejmech.2019.05.017_bib22","article-title":"Role of hydrogen sulfide in ischemia-reperfusion injury","volume":"16","author":"Wu","year":"2015","journal-title":"Oxidative medicine and cellular longevity"},{"issue":"14","key":"10.1016\/j.ejmech.2019.05.017_bib23","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1096\/fj.04-2279fje","article-title":"Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3","volume":"18","author":"Yang","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.ejmech.2019.05.017_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fchem.2017.00072","article-title":"Hydrogen sulfide: a worthwhile tool in the design of new multitarget drugs","volume":"5","author":"Sestito","year":"2017","journal-title":"Frontiers in chemistry"},{"key":"10.1016\/j.ejmech.2019.05.017_bib25","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.bcp.2017.11.014","article-title":"A\u00a0review of hydrogen sulfide (H2S) donors: chemistry and potential therapeutic applications","volume":"149","author":"Powell","year":"2018","journal-title":"Biochem. Pharmacol."},{"issue":"5","key":"10.1016\/j.ejmech.2019.05.017_bib26","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bcp.2012.10.019","article-title":"Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras","volume":"85","author":"Kashfi","year":"2013","journal-title":"Biochem. Pharmacol."},{"issue":"8","key":"10.1016\/j.ejmech.2019.05.017_bib27","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.jplph.2012.12.018","article-title":"Hydrogen sulfide donor sodium hydrosulfide-improved heat tolerance in maize and involvement of proline","volume":"170","author":"Li","year":"2013","journal-title":"J.\u00a0Plant Physiol."},{"issue":"5","key":"10.1016\/j.ejmech.2019.05.017_bib28","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1021\/acs.jmedchem.5b01223","article-title":"Synthesis and pharmacological evaluation of novel adenine\u2013hydrogen sulfide slow release hybrids designed as multitarget cardioprotective agents","volume":"59","author":"Lougiakis","year":"2016","journal-title":"J.\u00a0Med. Chem."},{"issue":"10","key":"10.1016\/j.ejmech.2019.05.017_bib29","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1039\/c3mb70145j","article-title":"Synthesis and evaluation of phosphorodithioate-based hydrogen sulfide donors","volume":"9","author":"Park","year":"2013","journal-title":"Mol. Biosyst."},{"issue":"6","key":"10.1016\/j.ejmech.2019.05.017_bib30","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1021\/cb400090d","article-title":"Controllable hydrogen sulfide donors and their activity against myocardial ischemia-reperfusion injury","volume":"8","author":"Zhao","year":"2013","journal-title":"ACS Chem. Biol."},{"issue":"25","key":"10.1016\/j.ejmech.2019.05.017_bib31","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1039\/C8CC01172A","article-title":"Light triggered uncaging of hydrogen sulfide (H 2 S) with real-time monitoring","volume":"54","author":"Venkatesh","year":"2018","journal-title":"Chem. Commun."},{"issue":"11","key":"10.1016\/j.ejmech.2019.05.017_bib32","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1021\/ol401118k","article-title":"Light-induced hydrogen sulfide release from \u201ccaged\u201d gem-dithiols","volume":"15","author":"Devarie-Baez","year":"2013","journal-title":"Org. Lett."},{"key":"10.1016\/j.ejmech.2019.05.017_bib33","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ejmech.2018.10.004","article-title":"Synthesis, toxicities and bio-activities of manganese complexes with CO and H2S dual donors","volume":"159","author":"Bai","year":"2018","journal-title":"Eur. J. Med. Chem."},{"issue":"16","key":"10.1016\/j.ejmech.2019.05.017_bib34","doi-asserted-by":"crossref","first-page":"6456","DOI":"10.1021\/acs.jmedchem.5b00848","article-title":"Discovery of new H2S releasing phosphordithioates and 2, 3-dihydro-2-phenyl-2-sulfanylenebenzo [d][1, 3, 2] oxazaphospholes with improved antiproliferative activity","volume":"58","author":"Feng","year":"2015","journal-title":"J.\u00a0Med. Chem."},{"issue":"20","key":"10.1016\/j.ejmech.2019.05.017_bib35","doi-asserted-by":"crossref","first-page":"6336","DOI":"10.1021\/jacs.6b01373","article-title":"pH-controlled hydrogen sulfide release for myocardial ischemia-reperfusion injury","volume":"138","author":"Kang","year":"2016","journal-title":"J.\u00a0Am. Chem. Soc."},{"issue":"11","key":"10.1016\/j.ejmech.2019.05.017_bib36","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1007\/BF00696722","article-title":"Synthesis and physiological activity of new organophosphorus pesticides of 1, 3, 2-oxazaphosphorinane series","volume":"44","author":"Shipov","year":"1995","journal-title":"Russ. Chem. Bull."},{"issue":"11","key":"10.1016\/j.ejmech.2019.05.017_bib37","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1021\/ol401118k","article-title":"Light-induced hydrogen sulfide release from \u201ccaged\u201d gem-dithiols","volume":"15","author":"Devarie-Baez","year":"2013","journal-title":"Org. Lett."},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10895-013-1296-5","article-title":"2, 6-dansyl azide as a fluorescent probe for hydrogen sulfide","volume":"24","author":"Wang","year":"2014","journal-title":"J.\u00a0Fluoresc."},{"issue":"18","key":"10.1016\/j.ejmech.2019.05.017_bib39","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/CIRCULATIONAHA.107.753467","article-title":"Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137)","volume":"117","author":"Li","year":"2008","journal-title":"Circulation"},{"issue":"17","key":"10.1016\/j.ejmech.2019.05.017_bib40","doi-asserted-by":"crossref","first-page":"7512","DOI":"10.1021\/acs.jmedchem.7b00888","article-title":"Iminothioethers as hydrogen sulfide donors: from the gasotransmitter release to the vascular effects","volume":"60","author":"Barresi","year":"2017","journal-title":"J.\u00a0Med. Chem."},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib41","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.vph.2013.11.003","article-title":"Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?","volume":"60","author":"Martelli","year":"2014","journal-title":"Vascular pharmacology"},{"key":"10.1016\/j.ejmech.2019.05.017_bib42","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.2741\/3480","article-title":"Teratogenic effects of sodium thiosulfate on developing zebrafish embryos","volume":"14","author":"Hu","year":"2009","journal-title":"Front. Biosci."},{"issue":"13","key":"10.1016\/j.ejmech.2019.05.017_bib43","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1161\/hc3801.095693","article-title":"Nitric oxide synthase (nNOS) gene transfer modifies venous bypass graft remodeling: effects on vascular smooth muscle cell differentiation and superoxide production","volume":"104","author":"West","year":"2001","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.ejmech.2019.05.017_bib44","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/sj.cdd.4400580","article-title":"Neuronal protection and destruction by NO","volume":"6","author":"Lipton","year":"1999","journal-title":"Cell Death Differ."},{"issue":"3","key":"10.1016\/j.ejmech.2019.05.017_bib45","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1471-4159.2004.02617.x","article-title":"The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite \u2018scavenger\u2019?","volume":"90","author":"Whiteman","year":"2004","journal-title":"J.\u00a0Neurochem."},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib46","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.bbrc.2006.02.154","article-title":"Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide","volume":"343","author":"Whiteman","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejmech.2019.05.017_bib47","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ejmech.2017.06.012","article-title":"Syntheses, toxicities and anti-inflammation of H2S-donors based on non-steroidal anti-inflammatory drugs","volume":"138","author":"Li","year":"2017","journal-title":"Eur. J. Med. Chem."},{"issue":"18","key":"10.1016\/j.ejmech.2019.05.017_bib48","doi-asserted-by":"crossref","first-page":"7501","DOI":"10.1021\/acs.jmedchem.5b01033","article-title":"Design, synthesis, and cardioprotective effects of N-mercapto-based hydrogen sulfide donors","volume":"58","author":"Zhao","year":"2015","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.ejmech.2019.05.017_bib49","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.cbi.2016.03.036","article-title":"Hydrogen sulfide modulates sub-cellular susceptibility to oxidative stress induced by myocardial ischemic reperfusion injury","volume":"252","author":"Ansari","year":"2016","journal-title":"Chem. Biol. Interact."},{"issue":"1","key":"10.1016\/j.ejmech.2019.05.017_bib50","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.taap.2013.08.019","article-title":"Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway","volume":"273","author":"Li","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"10","key":"10.1016\/j.ejmech.2019.05.017_bib51","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1177\/0960327114522278","article-title":"The effects of x-ray radiation on the eye development of zebrafish","volume":"33","author":"Zhou","year":"2014","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.ejmech.2019.05.017_bib52","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jhazmat.2012.02.014","article-title":"Toxicity assessment of zebrafish following exposure to CdTe QDs","volume":"213","author":"Zhang","year":"2012","journal-title":"J.\u00a0Hazard Mater."},{"issue":"3","key":"10.1016\/j.ejmech.2019.05.017_bib53","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dynam."},{"issue":"1\u20132","key":"10.1016\/j.ejmech.2019.05.017_bib54","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0022-1759(86)90215-2","article-title":"Use of MTT colorimetric assay to measure cell activation","volume":"94","author":"Gerlier","year":"1986","journal-title":"J.\u00a0Immunol. Methods"},{"issue":"29","key":"10.1016\/j.ejmech.2019.05.017_bib55","doi-asserted-by":"crossref","first-page":"18411","DOI":"10.1074\/jbc.272.29.18411","article-title":"Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells Involvement of superoxide and peroxynitrite anions","volume":"272","author":"Foresti","year":"1997","journal-title":"J.\u00a0Biol. Chem."}],"container-title":["European Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S022352341930426X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S022352341930426X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T22:26:34Z","timestamp":1559687194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S022352341930426X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":55,"alternative-id":["S022352341930426X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmech.2019.05.017","relation":{},"ISSN":["0223-5234"],"issn-type":[{"value":"0223-5234","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxicity, bioactivity, release of H2S in\u00a0vivo and pharmaco-kinetics of H2S-donors with thiophosphamide structure","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medicinal Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmech.2019.05.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}