{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T10:39:09Z","timestamp":1761734349197,"version":"build-2065373602"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medical Genetics"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.ejmg.2019.103785","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T11:34:25Z","timestamp":1570620865000},"page":"103785","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Intracranial vascular pathology in two further patients with Floating-Harbor syndrome: Proposals for cerebrovascular disease risk management"],"prefix":"10.1016","volume":"63","author":[{"given":"Lara","family":"Menzies","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felice","family":"D'Arco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijeya","family":"Ganesan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane A.","family":"Hurst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"19","key":"10.1016\/j.ejmg.2019.103785_bib1","doi-asserted-by":"crossref","first-page":"4413","DOI":"10.1093\/nar\/26.19.4413","article-title":"AT-hook motifs identified in a wide variety of DNA-binding proteins","volume":"26","author":"Aravind","year":"1998","journal-title":"Nucleic Acids Res."},{"issue":"4","key":"10.1016\/j.ejmg.2019.103785_bib2","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/ajmg.a.33252","article-title":"Majewski osteodysplastic primordial dwarfism type II (MOPD II): expanding the vascular phenotype","volume":"152A","author":"Bober","year":"2010","journal-title":"Am. J. Med. Genet."},{"issue":"4","key":"10.1016\/j.ejmg.2019.103785_bib3","doi-asserted-by":"crossref","first-page":"615","DOI":"10.3174\/ajnr.A4575","article-title":"Risk factors for growth of intracranial aneurysms: a systematic review and meta-analysis","volume":"37","author":"Brinjikji","year":"2016","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.ejmg.2019.103785_bib4","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1146\/annurev.biochem.77.062706.153223","article-title":"The biology of chromatin remodeling complexes","volume":"78","author":"Clapier","year":"2009","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ejmg.2019.103785_bib5","doi-asserted-by":"crossref","first-page":"1049 e1","DOI":"10.1016\/j.wneu.2017.05.083","article-title":"Treatment of moyamoya disease and unruptured intracranial aneurysm in floating-harbor syndrome","volume":"104","author":"Coughlin","year":"2017","journal-title":"World Neurosurg"},{"issue":"15","key":"10.1016\/j.ejmg.2019.103785_bib6","doi-asserted-by":"crossref","first-page":"6559","DOI":"10.1128\/MCB.25.15.6559-6569.2005","article-title":"Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathway","volume":"25","author":"Eissenberg","year":"2005","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.ejmg.2019.103785_bib7","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00062-011-0100-7","article-title":"Cervical artery dissection in a young patient with Rubinstein-Taybi syndrome","volume":"23","author":"Fischer","year":"2013","journal-title":"Clin. Neuroradiol."},{"issue":"2","key":"10.1016\/j.ejmg.2019.103785_bib8","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ajhg.2011.12.001","article-title":"Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome","volume":"90","author":"Hood","year":"2012","journal-title":"Am. J. Hum. Genet."},{"issue":"6","key":"10.1016\/j.ejmg.2019.103785_bib9","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0090-3019(90)90237-J","article-title":"Autopsy study of unruptured incidental intracranial aneurysms","volume":"34","author":"Inagawa","year":"1990","journal-title":"Surg. Neurol."},{"issue":"23","key":"10.1016\/j.ejmg.2019.103785_bib10","doi-asserted-by":"crossref","first-page":"16370","DOI":"10.1074\/jbc.274.23.16370","article-title":"Identification of a novel SNF2\/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein","volume":"274","author":"Johnston","year":"1999","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.ejmg.2019.103785_bib11","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1227\/01.NEU.0000311076.64109.2E","article-title":"Guidelines for the surgical treatment of unruptured intracranial aneurysms: the first annual J. Lawrence pool memorial research symposium--controversies in the management of cerebral aneurysms","volume":"62","author":"Komotar","year":"2008","journal-title":"Neurosurgery"},{"issue":"12","key":"10.1016\/j.ejmg.2019.103785_bib12","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1136\/jmedgenet-2016-103842","article-title":"When chromatin organisation floats astray: the Srcap gene and Floating-Harbor syndrome","volume":"53","author":"Messina","year":"2016","journal-title":"J. Med. Genet."},{"issue":"12","key":"10.1016\/j.ejmg.2019.103785_bib13","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1210\/me.2003-0208","article-title":"SNF2-related CBP activator protein (SRCAP) functions as a coactivator of steroid receptor-mediated transcription through synergistic interactions with CARM-1 and GRIP-1","volume":"17","author":"Monroy","year":"2003","journal-title":"Mol. Endocrinol."},{"issue":"3","key":"10.1016\/j.ejmg.2019.103785_bib14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S1474-4422(10)70327-6","article-title":"Paediatric stroke: genetic insights into disease mechanisms and treatment targets","volume":"10","author":"Munot","year":"2011","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ejmg.2019.103785_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1750-1172-8-63","article-title":"The phenotype of Floating-Harbor syndrome: clinical characterization of 52 individuals with mutations in exon 34 of SRCAP","volume":"8","author":"Nikkel","year":"2013","journal-title":"Orphanet J. Rare Dis."},{"issue":"2","key":"10.1016\/j.ejmg.2019.103785_bib16","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11102-012-0404-x","article-title":"Prevalence of cerebral aneurysm in patients with acromegaly","volume":"16","author":"Oshino","year":"2013","journal-title":"Pituitary"},{"issue":"4","key":"10.1016\/j.ejmg.2019.103785_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1097\/MCD.0b013e328306a38d","article-title":"Ruptured cerebral aneurysm in a patient with Floating-Harbor syndrome","volume":"17","author":"Paluzzi","year":"2008","journal-title":"Clin. Dysmorphol."},{"issue":"3","key":"10.1016\/j.ejmg.2019.103785_bib18","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1136\/jmg.28.3.201","article-title":"Floating-Harbor syndrome","volume":"28","author":"Patton","year":"1991","journal-title":"J. Med. Genet."},{"issue":"4","key":"10.1016\/j.ejmg.2019.103785_bib19","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.pediatrneurol.2012.12.010","article-title":"Screening for cerebrovascular disease in microcephalic osteodysplastic primordial dwarfism type II (MOPD II): an evidence-based proposal","volume":"48","author":"Perry","year":"2013","journal-title":"Pediatr. Neurol."},{"issue":"3","key":"10.1016\/j.ejmg.2019.103785_bib20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1001\/archneur.1993.00540030031010","article-title":"The clinical spectrum of unruptured intracranial aneurysms","volume":"50","author":"Raps","year":"1993","journal-title":"Arch. Neurol."},{"issue":"12","key":"10.1016\/j.ejmg.2019.103785_bib21","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1002\/ajmg.a.35635","article-title":"Floating-Harbor syndrome and polycystic kidneys associated with SRCAP mutation","volume":"158A","author":"Reschen","year":"2012","journal-title":"Am. J. Med. Genet."},{"issue":"1","key":"10.1016\/j.ejmg.2019.103785_bib22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000089512","article-title":"Alagille syndrome and aneurysmal subarachnoid hemorrhage. Case report and review of the literature","volume":"42","author":"Tumialan","year":"2006","journal-title":"Pediatr. Neurosurg."},{"issue":"4","key":"10.1016\/j.ejmg.2019.103785_bib23","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ajmg.a.33294","article-title":"The phenotype of Floating-Harbor syndrome in 10 patients","volume":"152A","author":"White","year":"2010","journal-title":"Am. J. Med. Genet."},{"issue":"9378","key":"10.1016\/j.ejmg.2019.103785_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0140-6736(03)13860-3","article-title":"Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment","volume":"362","author":"Wiebers","year":"2003","journal-title":"Lancet"},{"issue":"18","key":"10.1016\/j.ejmg.2019.103785_bib25","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.2217\/pgs-2016-0127","article-title":"Pathophysiology of aortic aneurysm: insights from human genetics and mouse models","volume":"17","author":"Wilson","year":"2016","journal-title":"Pharmacogenomics"}],"container-title":["European Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769721219303763?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769721219303763?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:48:21Z","timestamp":1761709701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1769721219303763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1769721219303763"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmg.2019.103785","relation":{},"ISSN":["1769-7212"],"issn-type":[{"type":"print","value":"1769-7212"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intracranial vascular pathology in two further patients with Floating-Harbor syndrome: Proposals for cerebrovascular disease risk management","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medical Genetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmg.2019.103785","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2019 Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103785"}}