{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:59:04Z","timestamp":1789207144862,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T00:00:00Z","timestamp":1658448000000},"content-version":"am","delay-in-days":324,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Medical Genetics"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.ejmg.2021.104287","type":"journal-article","created":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T05:01:39Z","timestamp":1625806899000},"page":"104287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Further refining the critical region of 10q26 microdeletion syndrome: A possible involvement of INSYN2 and NPS in the cognitive phenotype"],"prefix":"10.1016","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7847-2225","authenticated-orcid":false,"given":"Florian","family":"Cherik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathis","family":"Lepage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganaelle","family":"Remerand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Francannet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Delabaere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Salaun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Pebrel-Richard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laetitia","family":"Gouas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Vago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Tchirkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6302-9383","authenticated-orcid":false,"given":"Carole","family":"Goumy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"31","key":"10.1016\/j.ejmg.2021.104287_bib1","doi-asserted-by":"crossref","first-page":"4021","DOI":"10.1038\/onc.2013.362","article-title":"Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease","volume":"33","author":"Cook","year":"2014","journal-title":"Oncogene"},{"key":"10.1016\/j.ejmg.2021.104287_bib2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13064-018-0114-9","article-title":"Mutations in dock1 disrupt early Schwann cell development","volume":"13","author":"Cunningham","year":"2018","journal-title":"Neural Dev."},{"issue":"2","key":"10.1016\/j.ejmg.2021.104287_bib3","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/ajmg.a.37448","article-title":"Craniosynostosis in 10q26 deletion patients: a consequence of brain underdevelopment or altered suture biology?","volume":"170A","author":"Faria","year":"2016","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2431-13-59","article-title":"A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants","volume":"13","author":"Fenton","year":"2013","journal-title":"BMC Pediatr."},{"key":"10.1016\/j.ejmg.2021.104287_bib5","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.ejcb.2014.06.003","article-title":"Dock-family exchange factors in cell migration and disease","volume":"93","author":"Gadea","year":"2014","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.ejmg.2021.104287_bib6","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1038\/npp.2017.169","article-title":"Neuropeptide S induces acute anxiolysis by phospholipase C-dependent signaling within the medial amygdala","volume":"43","author":"Grund","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejmg.2021.104287_bib7","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00441-018-2902-2","article-title":"Brain neuropeptide S: via GPCR activation to a powerful neuromodulator of socio-emotional behaviors","volume":"375","author":"Grund","year":"2019","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.ejmg.2021.104287_bib8","first-page":"505832","article-title":"An interstitial deletion at 10q26.2q26.3","author":"Iourov","year":"2014","journal-title":"Case Rep Genet"},{"key":"10.1016\/j.ejmg.2021.104287_bib9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ajmg.a.20220","article-title":"Deletion of the distal long arm of chromosome 10; is there a characteristic phenotype? A report of 15 de novo and familial cases","volume":"123A","author":"Irving","year":"2003","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib10","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1002\/ajmg.a.37677","article-title":"Molecular and clinical analyses with neuropsychological assessment of a case of del(10)(q26.2qter) without intellectual disability: genomic and transcriptomic combined approach and review of the literature","volume":"170","author":"Laudier","year":"2016","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib11","doi-asserted-by":"crossref","first-page":"5134","DOI":"10.3892\/mmr.2016.5864","article-title":"Chromosome 10q26 deletion syndrome: two new cases and a review of the literature","volume":"14","author":"Lin","year":"2016","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.ejmg.2021.104287_bib12","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/ajmg.a.32705","article-title":"Molecular (SNP) analyses of overlapping hemizygous deletions of 10q25.3 to 10qter in four patients: evidence for HMX2 and HMX3 as candidate genes in hearing and vestibular function","volume":"149A","author":"Miller","year":"2009","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib13","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1046\/j.1523-1755.2000.00412.x","article-title":"Genetic evidence for a novel gene(s) involved in urogenital development on 10q26","volume":"58","author":"Ogata","year":"2000","journal-title":"Kidney Int."},{"key":"10.1016\/j.ejmg.2021.104287_bib14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejmg.2013.11.002","article-title":"Distal 10q monosomy: new evidence for a neurobehavioral condition?","volume":"57","author":"Plaisanci\u00e9","year":"2014","journal-title":"Eur. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib15","article-title":"WDR11 is another causative gene for coloboma, cardiac anomaly and growth retardation in 10q26 deletion syndrome","volume":"31","author":"Sutani","year":"2019","journal-title":"Eur. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib16","series-title":"Mild phenotype in a patient with a de novo 6.3 Mb distal deletion at 10q26.2q26.3","first-page":"242891","author":"Tanteles","year":"2015"},{"key":"10.1016\/j.ejmg.2021.104287_bib17","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1126\/science.aag0821","article-title":"Identification of an elaborate complex mediating postsynaptic inhibition","volume":"353","author":"Uezu","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.ejmg.2021.104287_bib18","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/ajmg.a.36949","article-title":"Clinical comparison of 10q26 overlapping deletions: delineating the critical region for urogenital anomalies","volume":"167A","author":"Vera-Carbonell","year":"2015","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ejmg.2021.104287_bib19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbaexp.2005.09.003","article-title":"Cloning and analysis of the murine Foxi2 transcription factor","volume":"1731","author":"Wijchers","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ejmg.2021.104287_bib20","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1399-0004.2008.01115.x","article-title":"Identification of critical regions for clinical features of distal 10q deletion syndrome","volume":"761","author":"Yatsenko","year":"2009","journal-title":"Clin. Genet."}],"container-title":["European Journal of Medical Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769721221001531?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1769721221001531?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:50:47Z","timestamp":1761709847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1769721221001531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1769721221001531"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmg.2021.104287","relation":{},"ISSN":["1769-7212"],"issn-type":[{"value":"1769-7212","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Further refining the critical region of 10q26 microdeletion syndrome: A possible involvement of INSYN2 and NPS in the cognitive phenotype","name":"articletitle","label":"Article Title"},{"value":"European Journal of Medical Genetics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmg.2021.104287","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104287"}}