{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:07:44Z","timestamp":1791421664527,"version":"4.3.3"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["physicamedica.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physica Medica"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.ejmp.2019.01.007","type":"journal-article","created":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T16:49:15Z","timestamp":1547743755000},"page":"215-220","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Implementation of proton therapy treatments with pencil beam scanning of targets with limited intrafraction motion"],"prefix":"10.1016","volume":"57","author":[{"given":"Francesco","family":"Fracchiolla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Dionisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Giacomelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Hild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Giorgio","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Lorentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Engwall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Amichetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmp.2019.01.007_b0005","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.ejmp.2016.05.064","article-title":"Required transition from research to clinical application: report on the 4D treatment planning workshops 2014 and 2015","volume":"32","author":"Knopf","year":"2016","journal-title":"Phys Med"},{"issue":"13","key":"10.1016\/j.ejmp.2019.01.007_b9005","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1088\/0031-9155\/47\/13\/302","article-title":"Effects of intra-fraction motion on IMRT dose delivery: statistical analysis and simulation","volume":"47","author":"Bortfeld","year":"2002","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ejmp.2019.01.007_b9010","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.3390\/cancers7030829","article-title":"Tumour movement in proton therapy: solutions and remaining questions: a review","volume":"7","author":"De Ruysscher","year":"2015","journal-title":"Cancers"},{"issue":"3","key":"10.1016\/j.ejmp.2019.01.007_b9015","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.radonc.2015.12.011","article-title":"Impact of fractionation and number of fields on dose homogeneity for intra-fractionally moving lung tumors using scanned carbon ion treatment","volume":"118","author":"W\u00f6lfelschneider","year":"2016","journal-title":"Radiother Oncol"},{"issue":"20","key":"10.1016\/j.ejmp.2019.01.007_b0010","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.1088\/0031-9155\/50\/20\/008","article-title":"Intrafractional motion during proton beam scanning","volume":"50","author":"Lambert","year":"2005","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ejmp.2019.01.007_b0015","doi-asserted-by":"crossref","first-page":"N283","DOI":"10.1088\/0031-9155\/54\/14\/N01","article-title":"Breathing interplay effects during proton beam scanning: simulation and statistical analysis","volume":"54","author":"Seco","year":"2009","journal-title":"Phys Med Biol"},{"issue":"9","key":"10.1016\/j.ejmp.2019.01.007_b0020","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1088\/0031-9155\/53\/9\/003","article-title":"Quantification of interplay effects of scanned particle beams and moving targets","volume":"53","author":"Bert","year":"2008","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ejmp.2019.01.007_b0025","doi-asserted-by":"crossref","first-page":"R113","DOI":"10.1088\/0031-9155\/56\/16\/R01","article-title":"Motion in radiotherapy: particle therapy","volume":"56","author":"Bert","year":"2011","journal-title":"Phys Med Biol"},{"issue":"2","key":"10.1016\/j.ejmp.2019.01.007_b0030","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/mp.12040","article-title":"Evaluation of motion mitigation using abdominal compression in the clinical implementation of pencil beam scanning proton therapy of liver tumors","volume":"44","author":"Lin","year":"2017","journal-title":"Med Phys"},{"issue":"3","key":"10.1016\/j.ejmp.2019.01.007_b0035","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.ijrobp.2005.05.066","article-title":"Reproducibility of liver position using active breathing coordinator for liver cancer radiotherapy","volume":"64","author":"Eccles","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.ejmp.2019.01.007_b0040","doi-asserted-by":"crossref","DOI":"10.1118\/1.3250856","article-title":"Respiratory motion management in particle therapy","volume":"37","author":"Rietzel","year":"2010","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2019.01.007_b0045","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.ijrobp.2008.11.014","article-title":"Gated irradiation with scanned particle beams","volume":"73","author":"Bert","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ejmp.2019.01.007_b0050","first-page":"63","article-title":"Effectiveness of different rescanning techniques for scanned proton radiotherapy in lung cancer patients","author":"Engwall","year":"2018","journal-title":"Phys Med Biol"},{"issue":"12","key":"10.1016\/j.ejmp.2019.01.007_b0055","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1118\/1.2815934","article-title":"Target motion tracking with a scanned particle beam","volume":"34","author":"Bert","year":"2007","journal-title":"Med Phys"},{"issue":"3","key":"10.1016\/j.ejmp.2019.01.007_b0060","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.ijrobp.2006.10.045","article-title":"4D proton treatment planning strategy for mobile lung tumors","volume":"67","author":"Kang","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ejmp.2019.01.007_b0065","first-page":"S72","article-title":"Mitigation of residual motion effects in scanned ion beam therapy","volume":"96","author":"Richter","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ejmp.2019.01.007_b0070","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1016\/j.ejmp.2016.11.107","article-title":"Commissioning of the 4-D treatment delivery system for organ motion management in synchrotron-based scanning ion beams","volume":"32","author":"Ciocca","year":"2016","journal-title":"Phys Med"},{"key":"10.1016\/j.ejmp.2019.01.007_b0075","doi-asserted-by":"crossref","unstructured":"Schwarz M, Algranati C, Widesott L, Farace P, Lorentini S, Righetto R, et al. Particle radiotherapy: emerging technology for treatment of cancer. In: Rath KA, Sahoo N, editors, New Delhi: Springer India; 2016, p. 95\u2013110. doi: 10.1007\/978-81-322-2622-2_7.","DOI":"10.1007\/978-81-322-2622-2_7"},{"issue":"2","key":"10.1016\/j.ejmp.2019.01.007_b0080","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.meddos.2018.02.013","article-title":"RayStation: external beam treatment planning system","volume":"43","author":"Bodensteiner","year":"2018","journal-title":"Med Dosim"},{"issue":"1","key":"10.1016\/j.ejmp.2019.01.007_b0085","doi-asserted-by":"crossref","DOI":"10.1118\/1.1531177","article-title":"Respiration-correlated spiral CT: a method of measuring respiratory-induced anatomic motion for radiation treatment planning","volume":"30","author":"Ford","year":"2003","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2019.01.007_b0090","doi-asserted-by":"crossref","DOI":"10.1088\/0031-9155\/52\/12\/012","article-title":"Phase and amplitude binning for 4D-CT imaging","author":"Abdelnour","year":"2007","journal-title":"Phys Med Biol"},{"issue":"1","key":"10.1016\/j.ejmp.2019.01.007_b0095","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1120\/jacmp.v7i1.2198","article-title":"Phase versus amplitude sorting of 4D-CT data","volume":"7","author":"Wink","year":"2006","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"10.1016\/j.ejmp.2019.01.007_b0100","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1118\/1.4894702","article-title":"The ANACONDA algorithm for deformable image registration in radiotherapy","volume":"42","author":"Weistrand","year":"2015","journal-title":"Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2019.01.007_b0105","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijrobp.2017.05.014","article-title":"Consensus guidelines for implementing pencil-beam scanning proton therapy for thoracic malignancies on behalf of the PTCOG thoracic and lymphoma subcommittee","volume":"99","author":"Chang","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ejmp.2019.01.007_b0110","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.radonc.2018.03.001","article-title":"Assessment of dosimetric errors induced by deformable image registration methods in 4D pencil beam scanned proton treatment planning for liver tumours","volume":"128","author":"Ribeiro","year":"2018","journal-title":"Radiother Oncol"}],"container-title":["Physica Medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179719300079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179719300079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T12:40:49Z","timestamp":1549802449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1120179719300079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":25,"alternative-id":["S1120179719300079"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmp.2019.01.007","relation":{},"ISSN":["1120-1797"],"issn-type":[{"value":"1120-1797","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Implementation of proton therapy treatments with pencil beam scanning of targets with limited intrafraction motion","name":"articletitle","label":"Article Title"},{"value":"Physica Medica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmp.2019.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}