{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T22:18:01Z","timestamp":1761171481938,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","physicamedica.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physica Medica"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.ejmp.2022.12.002","type":"journal-article","created":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T23:31:22Z","timestamp":1671319882000},"page":"102510","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A markerless beam\u2019s eye view tumor tracking algorithm based on unsupervised deformable registration learning framework of VoxelMorph in medical image with partial data"],"prefix":"10.1016","volume":"105","author":[{"given":"Jiajian","family":"Zhong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiming","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minmin","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ejmp.2022.12.002_b0005","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s00066-011-2236-4","article-title":"KV cone-beam CT-based IGRT: a clinical review","volume":"187","author":"Boda-Heggemann","year":"2011","journal-title":"Strahlenther Onkol"},{"issue":"10","key":"10.1016\/j.ejmp.2022.12.002_b0010","doi-asserted-by":"crossref","first-page":"e988","DOI":"10.1002\/mp.14312","article-title":"A modern review of the uncertainties in volumetric imaging of respiratory-induced target motion in lung radiotherapy","volume":"47","author":"Vergalasova","year":"2020","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2022.12.002_b0015","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2019.01.020","article-title":"Pancreatic cancer treated with SBRT: effect of anatomical interfraction variations on dose to organs at risk","volume":"134","author":"Loi","year":"2019","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.ejmp.2022.12.002_b0020","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/acm2.12847","article-title":"Dose deviations induced by respiratory motion for radiotherapy of lung tumors: Impact of CT reconstruction, plan complexity, and fraction size","volume":"21","author":"Sande","year":"2020","journal-title":"J Appl Clin Med Phy"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0025","first-page":"52","article-title":"Errors and margins in radiotherapy","volume":"11","author":"Herk","year":"2013","journal-title":"Semin Radiat Oncol"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0030","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13014-020-01734-w","article-title":"Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume","volume":"16","author":"Shimohigashi","year":"2021","journal-title":"Radiat Oncol"},{"issue":"7","key":"10.1016\/j.ejmp.2022.12.002_b0035","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.clon.2012.05.007","article-title":"Intensity-modulated radiotherapy in the treatment of lung cancer","volume":"24","author":"Bezjak","year":"2012","journal-title":"Clin Oncol-UK"},{"issue":"6","key":"10.1016\/j.ejmp.2022.12.002_b0040","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s00066-020-01685-x","article-title":"Long-term results of robotic radiosurgery for non brachytherapy patients with cervical cancer","volume":"197","author":"Morgenthaler","year":"2021","journal-title":"Strahlenther Onkol"},{"issue":"11","key":"10.1016\/j.ejmp.2022.12.002_b0045","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.1002\/mp.12516","article-title":"Registration free automatic identification of gold fiducial markers in MRI target delineation images for prostate radiotherapy","volume":"44","author":"Gustafsson","year":"2017","journal-title":"Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0050","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1118\/1.4903892","article-title":"Markerless motion tracking of lung tumors using dual-energy fluoroscopy","volume":"42","author":"Patel","year":"2015","journal-title":"Med Phys"},{"issue":"6","key":"10.1016\/j.ejmp.2022.12.002_b0055","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1007\/s00270-010-9949-0","article-title":"Complications associated with the percutaneous insertion of fiducial markers in the thorax","volume":"33","author":"Bhagat","year":"2010","journal-title":"Cardiovasc Inter Rad"},{"issue":"3","key":"10.1016\/j.ejmp.2022.12.002_b0060","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.21037\/jtd.2018.03.49","article-title":"Fiducial marker placement for stereotactic body radiation therapy via convex probe endobronchial ultrasound: a case series and review of literature","volume":"10","author":"Seides","year":"2018","journal-title":"J Thorac Dis"},{"issue":"5","key":"10.1016\/j.ejmp.2022.12.002_b0065","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.adro.2020.01.008","article-title":"Characterization of markerless tumor tracking using the on-board imager of a commercial linear accelerator equipped with fast-kV switching dual-energy imaging","volume":"5","author":"Roeske","year":"2020","journal-title":"Adv Radiat Oncol"},{"issue":"8","key":"10.1016\/j.ejmp.2022.12.002_b0070","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/ab79c5","article-title":"A machine learning-based real-time tumor tracking system for fluoroscopic gating of lung radiotherapy","volume":"65","author":"SaKata","year":"2020","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ejmp.2022.12.002_b0075","unstructured":"Winston JP, Best K, Plusquellic L, Thoma P, Gilley DB. Patient exposure and dose guide - 2003. 1st ed. Frankfort: Conference of Radiation Control Program Directors, Inc; 2003."},{"issue":"10","key":"10.1016\/j.ejmp.2022.12.002_b0080","doi-asserted-by":"crossref","first-page":"4041","DOI":"10.1118\/1.2775667","article-title":"The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75","volume":"34","author":"Murphy","year":"2007","journal-title":"Med Phys"},{"issue":"4","key":"10.1016\/j.ejmp.2022.12.002_b0085","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/acm2.12558","article-title":"Automatic detection of graticule isocenter and scale from kV and MV images","volume":"20","author":"Fang","year":"2019","journal-title":"J Appl Clin Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0090","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s13014-020-01611-6","article-title":"Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique","volume":"15","author":"Chen","year":"2020","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.ejmp.2022.12.002_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2020.573279","article-title":"Feasibility of optical surface-guidance for position verification and monitoring of stereotactic body radiotherapy in deep-inspiration breath-hold","volume":"10","author":"Naumann","year":"2020","journal-title":"Front Oncol"},{"issue":"7","key":"10.1016\/j.ejmp.2022.12.002_b0100","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1118\/1.2739811","article-title":"Accuracy of tumor motion compensation algorithm from a robotic respiratory tracking system: a simulation study","volume":"34","author":"Seppenwoolde","year":"2007","journal-title":"Med Phys"},{"issue":"5","key":"10.1016\/j.ejmp.2022.12.002_b0105","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1120\/jacmp.v14i5.4488","article-title":"Effect of audio instruction on tracking errors using a four-dimensional image-guided radiotherapy system","volume":"14","author":"Nakamura","year":"2013","journal-title":"J Appl Clin Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0110","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/s13014-019-1401-2","article-title":"Estimating intrafraction tumor motion during fiducial-based liver stereotactic radiotherapy via an iterative closest point (ICP) algorithm","volume":"14","author":"Li","year":"2019","journal-title":"Radia Oncol"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0115","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s13246-015-0327-8","article-title":"Use of a megavoltage electronic portal imaging device to identify prosthetic materials","volume":"38","author":"Moutrie","year":"2015","journal-title":"Australas Phys Eng Sci Med"},{"issue":"3","key":"10.1016\/j.ejmp.2022.12.002_b0120","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1088\/0031-9155\/54\/3\/013","article-title":"Computerized method for estimation of the location of a lung tumor on EPID cine images without implanted markers in stereotactic body radiotherapy","volume":"54","author":"Arimura","year":"2009","journal-title":"Phys Med Biol"},{"issue":"18","key":"10.1016\/j.ejmp.2022.12.002_b0125","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1088\/0031-9155\/55\/18\/021","article-title":"A multi-region algorithm for markerless beam's-eye view lung tumor tracking","volume":"55","author":"Rottmann","year":"2010","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ejmp.2022.12.002_b0130","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.mri.2020.09.013","article-title":"Balanced multi-image demons for non-rigid registration of magnetic resonance images","volume":"74","author":"Mesin","year":"2020","journal-title":"Magn Reson Imaging"},{"issue":"20","key":"10.1016\/j.ejmp.2022.12.002_b0135","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1161\/CIRCULATIONAHA.115.001593","article-title":"Machine learning in medicine","volume":"132","author":"Deo","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.ejmp.2022.12.002_b0140","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ejmp.2021.04.010","article-title":"Artificial intelligence applications in medical imaging: A review of the medical physics research in Italy","volume":"83","author":"Avanzo","year":"2021","journal-title":"Phys Med"},{"key":"10.1016\/j.ejmp.2022.12.002_b0145","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ejmp.2021.01.069","article-title":"Expanding the medical physicist curricular and professional programme to include Artificial Intelligence","volume":"83","author":"Zanca","year":"2021","journal-title":"Phys Med"},{"key":"10.1016\/j.ejmp.2022.12.002_b0150","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.neucom.2021.03.099","article-title":"Image stitching via deep homography estimation","volume":"450","author":"Zhao","year":"2021","journal-title":"Neurocomputing"},{"issue":"7","key":"10.1016\/j.ejmp.2022.12.002_b0155","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.3390\/rs13071294","article-title":"Unsupervised multistep deformable registration of remote sensing imagery based on deep learning","volume":"13","author":"Papadomanolaki","year":"2021","journal-title":"Remote Sens (Basel)"},{"key":"10.1016\/j.ejmp.2022.12.002_b0160","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.neuroimage.2017.07.008","article-title":"Quicksilver: Fast predictive image registration - a deep learning approach","volume":"158","author":"Yang","year":"2017","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejmp.2022.12.002_b0165","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.radonc.2020.09.048","article-title":"Identification of treatment error types for lung cancer patients using convolutional neural networks and EPID dosimetry","volume":"153","author":"Wolfs","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ejmp.2022.12.002_b0170","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.898771","article-title":"Real-time 2D MR cine from beam eye's view with tumor-volume projection to ensure beam-to-tumor conformality for MR-guided radiotherapy of lung cancer","volume":"12","author":"Nie","year":"2022","journal-title":"Front Oncol"},{"issue":"8","key":"10.1016\/j.ejmp.2022.12.002_b0175","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1109\/TMI.2019.2897538","article-title":"VoxelMorph: A learning framework for deformable medical image registration","volume":"38","author":"Balakrishnan","year":"2019","journal-title":"IEEE Trans Med Imaging"},{"issue":"Suppl 2","key":"10.1016\/j.ejmp.2022.12.002_b0180","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12859-020-3358-4","article-title":"A machine learning approach on multiscale texture analysis for breast microcalcification diagnosis","volume":"21","author":"Fanizzi","year":"2020","journal-title":"BMC Bioinf"},{"issue":"12","key":"10.1016\/j.ejmp.2022.12.002_b0185","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1016\/j.ultrasmedbio.2018.07.022","article-title":"Continuous inferior vena cava diameter tracking through an iterative kanade\u2013lucas\u2013tomasi-based algorithm","volume":"44","author":"Belmont","year":"2018","journal-title":"Ultrasound Med Bio"},{"issue":"15","key":"10.1016\/j.ejmp.2022.12.002_b0190","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.3390\/s19153263","article-title":"Vision-Based measurement of heart rate from ballistocardiographic head movements using unsupervised clustering","volume":"19","author":"Lee","year":"2019","journal-title":"Sensors"},{"issue":"8","key":"10.1016\/j.ejmp.2022.12.002_b0195","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1088\/1361-6560\/aa6393","article-title":"A bayesian approach for three-dimensional markerless tumor tracking using kV imaging during lung radiotherapy","volume":"62","author":"Shieh","year":"2017","journal-title":"Phys Med Biol"},{"issue":"11","key":"10.1016\/j.ejmp.2022.12.002_b0200","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/aac1a9","article-title":"Markerless positional verification using template matching and triangulation of kV images acquired during irradiation for lung tumors treated in breath-hold","volume":"63","author":"Hazelaar","year":"2018","journal-title":"Phys Med Biol"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13014-018-1191-y","article-title":"Simulation of dosimetry impact of 4DCT uncertainty in 4D dose calculation for lung SBRT","volume":"14","author":"Liu","year":"2019","journal-title":"Radiat Oncol"},{"issue":"6","key":"10.1016\/j.ejmp.2022.12.002_b0210","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/acm2.12612","article-title":"Nonrigid registration of medical image based on adaptive local structure tensor and normalized mutual information","volume":"20","author":"Yang","year":"2019","journal-title":"J Appl Clin Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2022.12.002_b0215","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.ijrobp.2009.03.008","article-title":"Do tumors in the lung deform during normal respiration? An image registration investigation","volume":"75","author":"Wu","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Physica Medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179722027065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179722027065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:52:38Z","timestamp":1761105158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1120179722027065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":43,"alternative-id":["S1120179722027065"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmp.2022.12.002","relation":{},"ISSN":["1120-1797"],"issn-type":[{"type":"print","value":"1120-1797"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A markerless beam\u2019s eye view tumor tracking algorithm based on unsupervised deformable registration learning framework of VoxelMorph in medical image with partial data","name":"articletitle","label":"Article Title"},{"value":"Physica Medica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmp.2022.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102510"}}