{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:58:24Z","timestamp":1793336304021,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001671","name":"European Synchrotron Radiation Facility","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001671","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","physicamedica.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physica Medica"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ejmp.2023.102571","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T22:24:21Z","timestamp":1679955861000},"page":"102571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Characterization of a CdTe single-photon-counting detector for biomedical imaging applications"],"prefix":"10.1016","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9734-8825","authenticated-orcid":false,"given":"Luca","family":"Fardin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1795-2940","authenticated-orcid":false,"given":"Camilla","family":"Giaccaglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3076-6608","authenticated-orcid":false,"given":"Paolo","family":"Busca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6868-2755","authenticated-orcid":false,"given":"Alberto","family":"Bravin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejmp.2023.102571_b0005","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.3390\/s90503491","article-title":"Progress in the Development of CdTe and CdZnTe Semiconductor Radiation Detectors for Astrophysical and Medical Applications","volume":"9","author":"Sordo","year":"2009","journal-title":"Sensors"},{"issue":"1","key":"10.1016\/j.ejmp.2023.102571_b0010","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0168-9002(01)00820-8","article-title":"GaAs structures for X-ray imaging detectors","volume":"466","author":"Ayzenshtat","year":"2001","journal-title":"Nucl Instrum Methods Phys Res Sect Accel Spectrometers Detect Assoc Equip"},{"issue":"21","key":"10.1016\/j.ejmp.2023.102571_b0015","doi-asserted-by":"crossref","first-page":"6743","DOI":"10.1088\/0031-9155\/57\/21\/6743","article-title":"Imaging properties of small-pixel spectroscopic x-ray detectors based on cadmium telluride sensors","volume":"57","author":"Koenig","year":"2012","journal-title":"Phys Med Biol"},{"issue":"10","key":"10.1016\/j.ejmp.2023.102571_b0020","doi-asserted-by":"crossref","first-page":"100901","DOI":"10.1118\/1.4820371","article-title":"Vision 20\/20: Single photon counting x-ray detectors in medical imaging","volume":"40","author":"Taguchi","year":"2013","journal-title":"Med Phys"},{"issue":"4","key":"10.1016\/j.ejmp.2023.102571_b0025","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1109\/TRPMS.2020.3002949","article-title":"Photon Counting Detectors for X-Ray Imaging With Emphasis on CT","volume":"5","author":"Ballabriga","year":"2021","journal-title":"IEEE Trans Radiat Plasma Med Sci"},{"key":"10.1016\/j.ejmp.2023.102571_b0030","first-page":"175","article-title":"Advances in micro-CT imaging of small animals","volume":"88","author":"Clark","year":"2021","journal-title":"Phys Medica Eur J Med Phys"},{"key":"10.1016\/j.ejmp.2023.102571_b0035","article-title":"Spectral CT imaging: Technical principles of dual-energy CT and multi-energy photon-counting CT","author":"Greffier","year":"2022","journal-title":"Diagn Interv Imaging"},{"key":"10.1016\/j.ejmp.2023.102571_b0040","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1109\/TNS.2011.2122267","article-title":"Evaluation of Energy Loss and Charge Sharing in Cadmium Telluride Detectors for Photon-Counting Computed Tomography","volume":"58","author":"Xu","year":"2011","journal-title":"IEEE Trans Nucl Sci"},{"key":"10.1016\/j.ejmp.2023.102571_b0045","doi-asserted-by":"crossref","first-page":"163220","DOI":"10.1016\/j.nima.2019.163220","article-title":"Characterization of the acquisition modes implemented in Pixirad-1\/Pixie-III X-ray Detector: Effects of charge sharing correction on spectral resolution and image quality","volume":"955","author":"Di Trapani","year":"2020","journal-title":"Nucl Instrum Methods Phys Res Sect Accel Spectrometers Detect Assoc Equip"},{"key":"10.1016\/j.ejmp.2023.102571_b0050","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevB.77.035205","article-title":"Nature of polarization in wide-bandgap semiconductor detectors under high-flux irradiation: Application to semi-insulating Cd(1\u2013x)Zn(x)Te","volume":"77","author":"Bale","year":"2008","journal-title":"Phys Rev B"},{"issue":"10","key":"10.1016\/j.ejmp.2023.102571_b0055","doi-asserted-by":"crossref","first-page":"102113","DOI":"10.1063\/1.3099051","article-title":"The polarization mechanism in CdTe Schottky detectors","volume":"94","author":"Cola","year":"2009","journal-title":"Appl Phys Lett"},{"issue":"02","key":"10.1016\/j.ejmp.2023.102571_b0060","doi-asserted-by":"crossref","first-page":"C02016","DOI":"10.1088\/1748-0221\/8\/02\/C02016","article-title":"The Medipix3RX: a high resolution, zero dead-time pixel detector readout chip allowing spectroscopic imaging","volume":"8","author":"Ballabriga","year":"2013","journal-title":"J Instrum"},{"issue":"01","key":"10.1016\/j.ejmp.2023.102571_b0065","doi-asserted-by":"crossref","first-page":"C01032","DOI":"10.1088\/1748-0221\/10\/01\/C01032","article-title":"PIXIE III: a very large area photon-counting CMOS pixel ASIC for sharp X-ray spectral imaging","volume":"10","author":"Bellazzini","year":"2015","journal-title":"J Instrum"},{"key":"10.1016\/j.ejmp.2023.102571_b0070","first-page":"316","article-title":"Phys. Med. Imaging, vol. 10573","volume":"2018","author":"Ullberg","year":"2018","journal-title":"SPIE"},{"key":"10.1016\/j.ejmp.2023.102571_b0075","first-page":"610","article-title":"IEEE Nucl","volume":"2012","author":"Loeliger","year":"2012","journal-title":"Sci Symp Med Imaging Conf Rec NSSMIC"},{"issue":"6","key":"10.1016\/j.ejmp.2023.102571_b0080","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1109\/TNS.2018.2832464","article-title":"IBEX: Versatile Readout ASIC With Spectral Imaging Capability and High Count Rate Capability","volume":"65","author":"Bochenek","year":"2018","journal-title":"IEEE Trans Nucl Sci"},{"issue":"13","key":"10.1016\/j.ejmp.2023.102571_b0085","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevLett.110.138105","article-title":"X-Ray Phase-Contrast Imaging with Nanoradian Angular Resolution","volume":"110","author":"Diemoz","year":"2013","journal-title":"Phys Rev Lett"},{"issue":"45","key":"10.1016\/j.ejmp.2023.102571_b0090","doi-asserted-by":"crossref","first-page":"18290","DOI":"10.1073\/pnas.1204460109","article-title":"High-resolution, low-dose phase contrast X-ray tomography for 3D diagnosis of human breast cancers","volume":"109","author":"Zhao","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.ejmp.2023.102571_b0095","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1148\/radiol.2020201622","article-title":"High-Spatial-Resolution Three-dimensional Imaging of Human Spinal Cord and Column Anatomy with Postmortem X-ray Phase-Contrast Micro-CT","volume":"298","author":"Barbone","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.ejmp.2023.102571_b0100","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.554668","article-title":"3D Spatial Distribution of Nanoparticles in Mice Brain Metastases by X-ray Phase-Contrast Tomography","volume":"11","author":"Longo","year":"2021","journal-title":"Front Oncol"},{"issue":"9","key":"10.1016\/j.ejmp.2023.102571_b0105","doi-asserted-by":"crossref","first-page":"e774","DOI":"10.1097\/CCM.0000000000003838","article-title":"Individual Airway Closure Characterized In Vivo by Phase-Contrast CT Imaging in Injured Rabbit Lung","volume":"47","author":"Broche","year":"2019","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.ejmp.2023.102571_b0110","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-77300-x","article-title":"Imaging atelectrauma in Ventilator-Induced Lung Injury using 4D X-ray microscopy","volume":"11","author":"Fardin","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejmp.2023.102571_b0115","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1107\/S1600577518006197","article-title":"Large-area single-photon-counting CdTe detector for synchrotron radiation computed tomography: a dedicated pre-processing procedure","volume":"25","author":"Brombal","year":"2018","journal-title":"J Synchrotron Radiat"},{"issue":"11","key":"10.1016\/j.ejmp.2023.102571_b0120","doi-asserted-by":"crossref","first-page":"C11014","DOI":"10.1088\/1748-0221\/12\/11\/C11014","article-title":"Optimization of the equalization procedure for a single-photon counting CdTe detector used for CT","volume":"12","author":"Delogu","year":"2017","journal-title":"J Instrum"},{"issue":"2-3","key":"10.1016\/j.ejmp.2023.102571_b0125","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0168-9002(99)00167-9","article-title":"Instrumentation of the ESRF medical imaging facility","volume":"428","author":"Elleaume","year":"1999","journal-title":"Nucl Instrum Methods Phys Res Sect Accel Spectrometers Detect Assoc Equip"},{"issue":"5","key":"10.1016\/j.ejmp.2023.102571_b0130","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1107\/S160057752000911X","article-title":"Multiscale pink-beam microCT imaging at the ESRF-ID17 biomedical beamline","volume":"27","author":"Mittone","year":"2020","journal-title":"J Synchrotron Radiat"},{"key":"10.1016\/j.ejmp.2023.102571_b0135","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1107\/S0909049500008384","article-title":"Fixed-exit monochromator for computed tomography with synchrotron radiation at energies 18\u201390 keV","volume":"7","author":"Suortti","year":"2000","journal-title":"J Synchrotron Radiat"},{"issue":"05","key":"10.1016\/j.ejmp.2023.102571_b0140","doi-asserted-by":"crossref","first-page":"C05056","DOI":"10.1088\/1748-0221\/9\/05\/C05056","article-title":"Comparator threshold settings and the effective pixel width of the PICASSO detector","volume":"9","author":"Lopez","year":"2014","journal-title":"J Instrum"},{"issue":"12","key":"10.1016\/j.ejmp.2023.102571_b0145","doi-asserted-by":"crossref","first-page":"C12008","DOI":"10.1088\/1748-0221\/13\/12\/C12008","article-title":"Characterization of noise and efficiency of the Pixirad-1\/Pixie-III CdTe X-ray imaging detector","volume":"13","author":"Trapani","year":"2018","journal-title":"J Instrum"},{"issue":"3","key":"10.1016\/j.ejmp.2023.102571_b0150","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1118\/1.3556561","article-title":"Dosimetry protocol for the forthcoming clinical trials in synchrotron stereotactic radiation therapy (SSRT)","volume":"38","author":"Prezado","year":"2011","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2023.102571_b0155","article-title":"X-Ray Mass Attenuation Coefficients","author":"Hubbel","year":"2009","journal-title":"NIST"},{"key":"10.1016\/j.ejmp.2023.102571_b0160","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1117\/12.55783","article-title":"Characterizing digital image acquisition devices","volume":"30","author":"Reichenbach","year":"1991","journal-title":"Opt Eng"},{"key":"10.1016\/j.ejmp.2023.102571_b0165","first-page":"1","article-title":"IEEE Nucl. Sci. Symp. Med. Imaging Conf","volume":"2016","author":"Johng-ay","year":"2016","journal-title":"Room-Temp Semicond Detect Workshop NSSMICRTSD"},{"key":"10.1016\/j.ejmp.2023.102571_b0170","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1118\/1.598623","article-title":"Noise power spectra of images from digital mammography detectors","volume":"26","author":"Williams","year":"1999","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2023.102571_b0175","doi-asserted-by":"crossref","unstructured":"A. Owens Semiconductor Radiation Detectors 1st ed. 2019 CRC Press Boca Raton 10.1201\/b22251.","DOI":"10.1201\/b22251"},{"key":"10.1016\/j.ejmp.2023.102571_b0180","unstructured":"International Electrotechnical Commission. IEC 62220-1-1:2015 - Medical electrical equipment - Characteristics of digital X-ray imaging devices - Part 1-1: Determination of the detective quantum efficiency - Detectors used in radiographic imaging 2015."},{"key":"10.1016\/j.ejmp.2023.102571_b0185","series-title":"Image science : principles, analysis and evaluation of photographic-type imaging processes","author":"Dainty","year":"1974"},{"key":"10.1016\/j.ejmp.2023.102571_b0190","doi-asserted-by":"crossref","unstructured":"Friedman SN, Cunningham IA. A method to measure the temporal MTF to determine the DQE of fluoroscopy systems. Med. Imaging 2006 Phys. Med. Imaging, vol. 6142, Proc. SPIE; 2006, p. 686\u201396. https:\/\/doi.org\/10.1117\/12.654516.","DOI":"10.1117\/12.654516"},{"key":"10.1016\/j.ejmp.2023.102571_b0195","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.nima.2018.03.006","article-title":"Spectral response characterization of CdTe sensors of different pixel size with the IBEX ASIC","volume":"892","author":"Zambon","year":"2018","journal-title":"Nucl Instrum Methods Phys Res Sect Accel Spectrometers Detect Assoc Equip"},{"key":"10.1016\/j.ejmp.2023.102571_b0200","doi-asserted-by":"crossref","first-page":"C04030","DOI":"10.1088\/1748-0221\/9\/04\/C04030","article-title":"Defect signature, instabilities and polarization in CdTe X-ray sensors with quasi-ohmic contacts","volume":"9","author":"Ruat","year":"2014","journal-title":"J Instrum"},{"issue":"12","key":"10.1016\/j.ejmp.2023.102571_b0205","doi-asserted-by":"crossref","first-page":"C12026","DOI":"10.1088\/1748-0221\/9\/12\/C12026","article-title":"The LAMBDA photon-counting pixel detector and high-Z sensor development","volume":"9","author":"Pennicard","year":"2014","journal-title":"J Instrum"},{"key":"10.1016\/j.ejmp.2023.102571_b0210","article-title":"Temporal and spatial variance in pixelated counting detectors with dead time and retrigger capability","volume":"1032","author":"Zambon","year":"2022","journal-title":"Nucl Instrum Methods Phys Res Sect Accel Spectrometers Detect Assoc Equip"}],"container-title":["Physica Medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179723000480?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179723000480?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:53:40Z","timestamp":1761105220000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1120179723000480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":42,"alternative-id":["S1120179723000480"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmp.2023.102571","relation":{},"ISSN":["1120-1797"],"issn-type":[{"value":"1120-1797","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of a CdTe single-photon-counting detector for biomedical imaging applications","name":"articletitle","label":"Article Title"},{"value":"Physica Medica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmp.2023.102571","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102571"}}