{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:41:08Z","timestamp":1792183268209,"version":"4.4.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","physicamedica.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Physica Medica"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.ejmp.2025.104929","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T11:52:52Z","timestamp":1739274772000},"page":"104929","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Assessment of the use of synthetic CT produced by deformable image registration of planning CT and CBCT in adaptive radiotherapy treatments of head and neck cancers"],"prefix":"10.1016","volume":"131","author":[{"given":"Sanju","family":"Sanju","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Mukherji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sambit S.","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubham","family":"Dokania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Kataria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narender","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Saini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Barman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandpani R.","family":"Epili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Choubey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninad H.","family":"Patil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ejmp.2025.104929_b0005","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1002\/mp.12256","article-title":"Use of image registration and fusion algorithms and techniques in radiotherapy: report of the AAPM Radiation Therapy Committee Task Group No. 132","volume":"44","author":"Brock","year":"2017","journal-title":"Med Phys"},{"issue":"9","key":"10.1016\/j.ejmp.2025.104929_b0010","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1080\/0284186X.2019.1620331","article-title":"Deformable image registration for radiation therapy: principle, methods, applications, and evaluation","volume":"58","author":"Rigaud","year":"2019","journal-title":"Acta Oncol Stockh Swed"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0015","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3857\/roj.2017.00325","article-title":"Deformable image registration in radiation therapy","volume":"35","author":"Oh","year":"2017","journal-title":"Radiat Oncol J"},{"issue":"10","key":"10.1016\/j.ejmp.2025.104929_b0020","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1080\/0284186X.2018.1505053","article-title":"Adaptive radiotherapy for head and neck cancer","volume":"57","author":"Castelli","year":"2018","journal-title":"Acta Oncol Stockh Swed"},{"key":"10.1016\/j.ejmp.2025.104929_b0025","doi-asserted-by":"crossref","unstructured":"Kataria T, Gupta D, Goyal S, Bisht SS, Abhishek A, Subramani V, et al. Clinical outcomes of adaptive radiotherapy in head and neck cancers. Br J Radiol. 89(1062):20160085. https:\/\/doi.org\/10.1259\/bjr.20160085.","DOI":"10.1259\/bjr.20160085"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0030","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1177\/1533034616662165","article-title":"Adaptive radiotherapy for head and neck cancer","volume":"16","author":"Surucu","year":"2017","journal-title":"Technol Cancer Res Treat"},{"key":"10.1016\/j.ejmp.2025.104929_b0035","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.oraloncology.2018.08.010","article-title":"Adaptive radiotherapy for head and neck cancer: are we ready to put it into routine clinical practice?","volume":"86","author":"Gensheimer","year":"2018","journal-title":"Oral Oncol"},{"key":"10.1016\/j.ejmp.2025.104929_b0040","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13014-014-0318-z","article-title":"Impact of head and neck cancer adaptive radiotherapy to spare the parotid glands and decrease the risk of xerostomia","volume":"10","author":"Castelli","year":"2015","journal-title":"Radiat Oncol Lond Engl"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0045","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijrobp.2005.07.957","article-title":"Repeat CT imaging and replanning during the course of IMRT for head-and-neck cancer","volume":"64","author":"Hansen","year":"2006","journal-title":"Int J Radiat Oncol"},{"issue":"1","key":"10.1016\/j.ejmp.2025.104929_b0050","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/j.ijrobp.2012.09.033","article-title":"Replanning during intensity modulated radiation therapy improved quality of life in patients with nasopharyngeal carcinoma","volume":"85","author":"Yang","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0055","first-page":"146","article-title":"Dose calculation accuracy of different image value to density tables for cone-beam CT planning in head & neck and pelvic localizations","volume":"31","author":"Barateau","year":"2015","journal-title":"Phys Medica PM Int J Devoted Appl Phys Med Biol Off J Ital Assoc Biomed Phys AIFB"},{"key":"10.1016\/j.ejmp.2025.104929_b0060","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1748-717X-3-42","article-title":"Investigation of the usability of cone-beam CT data sets for dose calculation","volume":"3","author":"Richter","year":"2008","journal-title":"Radiat Oncol Lond Engl"},{"key":"10.1016\/j.ejmp.2025.104929_b0065","doi-asserted-by":"crossref","unstructured":"Marchant TE, Joshi KD, Moore CJ. Shading correction for cone-beam CT in radiotherapy: validation of dose calculation accuracy using clinical images. In: Medical Imaging 2017: Physics of Medical Imaging. Vol 10132. SPIE; 2017:119-129. https:\/\/doi.org\/10.1117\/12.2254059.","DOI":"10.1117\/12.2254059"},{"issue":"1096","key":"10.1016\/j.ejmp.2025.104929_b0070","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20180383","article-title":"An evaluation of techniques for dose calculation on cone beam computed tomography","volume":"92","author":"Giacometti","year":"2019","journal-title":"Br J Radiol"},{"issue":"5","key":"10.1016\/j.ejmp.2025.104929_b0075","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1259\/dmfr\/30642039","article-title":"Artefacts in CBCT: a review","volume":"40","author":"Schulze","year":"2011","journal-title":"Dento Maxillo Facial Radiol"},{"key":"10.1016\/j.ejmp.2025.104929_b0080","unstructured":"Varian Medical Systems. Velocity 4.0 Instructions for Use. https:\/\/www.myvarian.com\/s\/productdocumentationdetail?Id=06944000003dEYSAA2&lang=en; 2024 [accessed 14 May 2024]."},{"key":"10.1016\/j.ejmp.2025.104929_b0085","unstructured":"Fox T, Andl G, Bose S. Velocity and Deformable Image Registration. https:\/\/varian.widen.net\/view\/pdf\/dizhixzecz\/VelocityClinicalPerspectives_RAD10438_February2018.pdf?u=bmxzem; 2018 [accessed 1 January 2024]."},{"key":"10.1016\/j.ejmp.2025.104929_b0090","first-page":"463","article-title":"Non-rigid image registration using a statistical spline deformation model","volume":"18","author":"Loeckx","year":"2003","journal-title":"Inf Process Med Imaging Proc Conf"},{"issue":"4","key":"10.1016\/j.ejmp.2025.104929_b0095","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1120\/jacmp.v8i4.2432","article-title":"Quantitative evaluation of a cone\u2010beam computed tomography\u2013planning computed tomography deformable image registration method for adaptive radiation therapy","volume":"8","author":"Lawson","year":"2007","journal-title":"J Appl Clin Med Phys"},{"issue":"5","key":"10.1016\/j.ejmp.2025.104929_b0100","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1109\/42.640755","article-title":"A methodology for evaluation of boundary detection algorithms on medical images","volume":"16","author":"Chalana","year":"1997","journal-title":"IEEE Trans Med Imaging"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0105","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S1076-6332(03)00671-8","article-title":"Statistical validation of image segmentation quality based on a spatial overlap index","volume":"11","author":"Zou","year":"2004","journal-title":"Acad Radiol"},{"key":"10.1016\/j.ejmp.2025.104929_b0110","unstructured":"Reinke A, Tizabi MD, Sudre CH, Almotairi M, Zeng M, Kumar V, et al. Common Limitations of Image Processing Metrics: A Picture Story. ArXiv. Published online 2021. https:\/\/doi.org\/10.48550\/arXiv.2104.05642."},{"issue":"4","key":"10.1016\/j.ejmp.2025.104929_b0115","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1118\/1.3690466","article-title":"Quality assurance for image-guided radiation therapy utilizing CT-based technologies: a report of the AAPM TG-179","volume":"39","author":"Bissonnette","year":"2012","journal-title":"Med Phys"},{"key":"10.1016\/j.ejmp.2025.104929_b0120","article-title":"Practical and technical key challenges in head and neck adaptive radiotherapy: the GORTEC point of view","volume":"109","author":"Delaby","year":"2023","journal-title":"Phys Medica Eur J Med Phys"},{"issue":"suppl_1","key":"10.1016\/j.ejmp.2025.104929_b0125","doi-asserted-by":"crossref","first-page":"i120","DOI":"10.1093\/jrr\/rrt045","article-title":"Performance validation of deformable image registration in the pelvic region","volume":"54","author":"Zambrano","year":"2013","journal-title":"J Radiat Res (Tokyo)"},{"key":"10.1016\/j.ejmp.2025.104929_b0130","first-page":"1","article-title":"Commissioning and validation of commercial deformable image registration software for adaptive contouring","volume":"47","author":"Jamema","year":"2018","journal-title":"Phys Medica PM Int J Devoted Appl Phys Med Biol Off J Ital Assoc Biomed Phys AIFB"},{"issue":"3","key":"10.1016\/j.ejmp.2025.104929_b0135","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.ijrobp.2014.06.045","article-title":"Deformable image registration for adaptive radiation therapy of head and neck cancer: accuracy and precision in the presence of tumor changes","volume":"90","author":"Mencarelli","year":"2014","journal-title":"Int J Radiat Oncol"},{"issue":"12","key":"10.1016\/j.ejmp.2025.104929_b0140","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/acm2.12773","article-title":"Structure guided deformable image registration for treatment planning CT and post stereotactic body radiation therapy (SBRT) Primovist\u00ae (Gd-EOB-DTPA) enhanced MRI","volume":"20","author":"Kuznetsova","year":"2019","journal-title":"J Appl Clin Med Phys"},{"issue":"2","key":"10.1016\/j.ejmp.2025.104929_b0145","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/mp.12737","article-title":"Performance of commercially available deformable image registration platforms for contour propagation using patient-based computational phantoms: a multi-institutional study","volume":"45","author":"Loi","year":"2018","journal-title":"Med Phys"},{"issue":"3","key":"10.1016\/j.ejmp.2025.104929_b0150","doi-asserted-by":"crossref","DOI":"10.1118\/1.4864240","article-title":"Toward adaptive radiotherapy for head and neck patients: Feasibility study on using CT-to-CBCT deformable registration for \u201cdose of the day\u201d calculations","volume":"41","author":"Veiga","year":"2014","journal-title":"Med Phys"},{"issue":"1","key":"10.1016\/j.ejmp.2025.104929_b0155","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13014-022-02191-3","article-title":"Dosimetric comparison of deformable image registration and synthetic CT generation based on CBCT images for organs at risk in cervical cancer radiotherapy","volume":"18","author":"Chang","year":"2023","journal-title":"Radiat Oncol Lond Engl"},{"issue":"6","key":"10.1016\/j.ejmp.2025.104929_b0160","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1002\/mp.14121","article-title":"CBCT-based synthetic CT generation using deep-attention cycleGAN for pancreatic adaptive radiotherapy","volume":"47","author":"Liu","year":"2020","journal-title":"Med Phys"}],"container-title":["Physica Medica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179725000390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1120179725000390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T18:27:00Z","timestamp":1752690420000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1120179725000390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":32,"alternative-id":["S1120179725000390"],"URL":"https:\/\/doi.org\/10.1016\/j.ejmp.2025.104929","relation":{},"ISSN":["1120-1797"],"issn-type":[{"value":"1120-1797","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of the use of synthetic CT produced by deformable image registration of planning CT and CBCT in adaptive radiotherapy treatments of head and neck cancers","name":"articletitle","label":"Article Title"},{"value":"Physica Medica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejmp.2025.104929","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104929"}}