{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:32:12Z","timestamp":1793291532339,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.ejogrb.2004.04.038","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T14:05:09Z","timestamp":1100613909000},"page":"214-218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["The relation of serum and follicular fluid leptin and ovarian steroid levels in response to induction of ovulation in in vitro fertilization cycles"],"prefix":"10.1016","volume":"118","author":[{"given":"Birg\u00fcl","family":"G\u00fcrb\u00fcz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serap","family":"Yalti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Ficicioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seval","family":"Ta\u015fdemir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2004.04.038_bib1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/372425a0","article-title":"Positional cloning of the mouse ob gene and its human homologue","volume":"372","author":"Zhang","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ejogrb.2004.04.038_bib2","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1126\/science.7624778","article-title":"Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks","volume":"269","author":"Campfield","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.ejogrb.2004.04.038_bib3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1126\/science.7624777","article-title":"Weight reducing effects of the plasma protein encoded by the obese gene","volume":"269","author":"Halaas","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.ejogrb.2004.04.038_bib4","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1172\/JCI118254","article-title":"Recombinant ob protein reduces feeding and body weight in the ob\/ob mouse","volume":"96","author":"Weigle","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib5","first-page":"1293","article-title":"The metabolic significance of leptin in humans gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure","volume":"82","author":"Kennedy","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib6","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/nm1195-1155","article-title":"Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects","volume":"1","author":"Maffei","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/nm1295-1311","article-title":"Leptin reflects body lipid content in mice: evidence for diet-induced leptin resistance","volume":"1","author":"Friderich","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib8","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1056\/NEJM199602013340503","article-title":"Serum immunoreactive leptin concentrations in normal weight and obese humans","volume":"334","author":"Considine","year":"1996","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib9","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/ng0398-213","article-title":"A leptin mutation associated with hypogonadism and morbid obesity","volume":"18","author":"Strobel","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib10","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/molehr\/3.6.467","article-title":"The expression of leptin and its receptors in pre-ovulatory human follicles","volume":"3","author":"Cioffi","year":"1997","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib11","first-page":"4144","article-title":"Expression of functional leptin receptors in the human ovary","volume":"82","author":"Karlsson","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib12","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/nm0997-1029","article-title":"Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans","volume":"3","author":"Masuzaki","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib13","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nm0596-585","article-title":"Novel B 219\/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction","volume":"2","author":"Cioffi","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib14","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/molehr\/3.12.1067","article-title":"Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and oocytes and differentially distributed within cells of the preimplantation stage embryo","volume":"3","author":"Antczak","year":"1997","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib15","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1210\/endo.138.8.5311","article-title":"The adipose obese gene product, leptin: evidence of a direct inhibitory role in ovarian function","volume":"138","author":"Spicer","year":"1997","journal-title":"Endocrinology"},{"issue":"abstract book 1","key":"10.1016\/j.ejogrb.2004.04.038_bib16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/humrep\/12.Suppl_2.68","article-title":"Leptin antogonizes IGF I augmentation of FSH-stimulated oestradiol production in human granulosa cells","volume":"12","author":"Agarwal","year":"1997","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib17","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/nm0996-949b","article-title":"Gender differences in plasma leptin concentrations","volume":"2","author":"Havel","year":"1996","journal-title":"Nat. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1677\/joe.0.1540285","article-title":"Estrogen increases in vivo leptin production in rats and human subjects","volume":"154","author":"Shimizu","year":"1997","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib19","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3109\/09513599809015540","article-title":"Increase in serum leptin concentrations in women undergoing controlled ovarian hyperstimulation for assisted reproduction","volume":"12","author":"Strowitzki","year":"1998","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib20","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1210\/jcem.84.9.6004","article-title":"Serum versus follicular fluid leptin in vitro fertilization: relationship among leptin increase, body fat mass and reduced ovarian response","volume":"84","author":"B\u00fctzow","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib21","first-page":"121","article-title":"Serum leptin concentrations in women during gonadotropin stimulation cycles","volume":"45","author":"Zhao","year":"2000","journal-title":"J. Reprod. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib22","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0015-0282(99)00578-6","article-title":"Circulating leptin levels during ovulation induction: relation to adiposity and ovarian morphology","volume":"73","author":"Lindheim","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib23","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000010228","article-title":"Serum leptin profiles in the normal menstrual cycles and gonadotropin treatment cycles","volume":"49","author":"Yamada","year":"2000","journal-title":"Gynecol. Obstet. Invest."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib24","first-page":"1687","article-title":"Leptin concentrations in the polycystic ovary syndrome","volume":"82","author":"Mantzoros","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1365-2265.1997.2441017.x","article-title":"Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy","volume":"47","author":"Hardie","year":"1997","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib26","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1093\/humrep\/13.5.1152","article-title":"Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone","volume":"13","author":"Messinis","year":"1998","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib27","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1530\/eje.0.1390190","article-title":"Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women","volume":"139","author":"Teirmaa","year":"1998","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib28","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1023\/A:1014889928191","article-title":"Leptin affects pregnancy outcome of in vitro fertilization and steroidogenesis of human granulosa cells","volume":"19","author":"Tsai","year":"2002","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib29","first-page":"3267","article-title":"Reversal of the sex difference in serum leptin levels upon cross-sex hormone administration in trans-sexuals","volume":"82","author":"Elbers","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib30","doi-asserted-by":"crossref","first-page":"871","DOI":"10.7326\/0003-4819-130-8-199904200-00014","article-title":"The role of leptin human obesity and disease: a review of current evidence","volume":"130","author":"Mantzoros","year":"1999","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib31","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/humrep\/14.4.913","article-title":"Leptin concentrations in normal women following bilateral ovariectomy","volume":"14","author":"Messinis","year":"1999","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib32","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1093\/humrep\/15.11.2383","article-title":"Treatment of normal women with estradiol plus progesterone prevents the decrease of leptin concentrations induced by ovariectomy","volume":"15","author":"Messinis","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib33","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1093\/humrep\/16.9.1827","article-title":"Oestradiol plus progesterone treatment increases serum leptin concentrations in normal women","volume":"16","author":"Messinis","year":"2001","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib34","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1034\/j.1600-0412.2000.079011931.x","article-title":"Effects of leptin on basal and FSH stimulated steroidogenesis in human granulosa luteal cells","volume":"79","author":"Greisen","year":"2000","journal-title":"Acta Obstet. Scand."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib35","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/humrep\/15.3.539","article-title":"Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome","volume":"15","author":"Mantzoros","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib36","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/humrep\/16.4.657","article-title":"Leptin during assisted reproductive cycles: the effect of ovarian stimulation and of very early pregnancy","volume":"16","author":"Unkila-Kallio","year":"2001","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ejogrb.2004.04.038_bib37","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1093\/humrep\/16.9.1819","article-title":"Baseline nonfasting serum leptin concentration to body mass index ratio is predictive of IVF outcomes","volume":"16","author":"Brannian","year":"2001","journal-title":"Hum. Reprod."}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030121150400377X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030121150400377X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:40:56Z","timestamp":1793288456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030121150400377X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S030121150400377X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2004.04.038","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The relation of serum and follicular fluid leptin and ovarian steroid levels in response to induction of ovulation in in vitro fertilization cycles","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2004.04.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}