{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:28:06Z","timestamp":1759624086521,"version":"build-2065373602"},"reference-count":15,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.ejogrb.2005.01.017","type":"journal-article","created":{"date-parts":[[2005,2,21]],"date-time":"2005-02-21T07:19:03Z","timestamp":1108970343000},"page":"172-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Placental localization and expression of the cell death factors BNip3 and Nix in preeclampsia, intrauterine growth retardation and HELLP syndrome"],"prefix":"10.1016","volume":"122","author":[{"given":"H.","family":"Stepan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Leo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Purz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"H\u00f6ckel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.-C.","family":"Horn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2005.01.017_bib1","first-page":"271","article-title":"Placental apoptosis in preeclampsia","volume":"96","author":"Allaire","year":"2000","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0002-9440(10)65123-1","article-title":"Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall","volume":"155","author":"DiFederico","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1053\/plac.2002.0878","article-title":"The \u2018reference trap\u2019 revisited: examples of the dangers in using ratios to describe fetoplacental angiogenesis and trophoblast turnover","volume":"24","author":"Mayhew","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib4","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1053\/plac.2002.0903","article-title":"Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulation","volume":"24","author":"Huppertz","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib5","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1053\/plac.2002.0946","article-title":"Pre-eclampsia and maternal anaemia display reduced apoptosis and opposite invasive phenotypes of extravillous trophoblast","volume":"24","author":"Kadyrov","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1074\/jbc.274.1.7","article-title":"Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins","volume":"274","author":"Chen","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib7","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1023\/A:1023616620970","article-title":"BNips: a group of pro-apoptotic proteins in the Bcl-2 family","volume":"8","author":"Zhang","year":"2003","journal-title":"Apoptosis"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib8","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1074\/jbc.275.2.1439","article-title":"BNIP3 heterodimerizes with Bcl-2\/Bcl-XL and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites","volume":"275","author":"Ray","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1067\/mob.2000.107928","article-title":"Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy","volume":"183","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1067\/mob.2002.119176","article-title":"Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation","volume":"186","author":"Ishihara","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib11","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1067\/mob.2002.122250","article-title":"Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression","volume":"186","author":"Levy","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib12","first-page":"6669","article-title":"HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors","volume":"61","author":"Sowter","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib13","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1385\/ENDO:19:1:103","article-title":"Role of placenta in preeclampsia","volume":"19","author":"Myatt","year":"2002","journal-title":"Endocrine"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib14","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0143-4004(97)90000-X","article-title":"Oxygen and placental villous development: origins of fetal hypoxia","volume":"18","author":"Kingdom","year":"1997","journal-title":"Placenta"},{"key":"10.1016\/j.ejogrb.2005.01.017_bib15","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/biolreprod\/64.2.499","article-title":"Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia","volume":"64","author":"Rajakumar","year":"2001","journal-title":"Biol Reprod"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211505000254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211505000254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:14:43Z","timestamp":1759554883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211505000254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0301211505000254"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2005.01.017","relation":{},"ISSN":["0301-2115"],"issn-type":[{"type":"print","value":"0301-2115"}],"subject":[],"published":{"date-parts":[[2005,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Placental localization and expression of the cell death factors BNip3 and Nix in preeclampsia, intrauterine growth retardation and HELLP syndrome","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2005.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}