{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:43:04Z","timestamp":1762864984663,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.ejogrb.2005.07.019","type":"journal-article","created":{"date-parts":[[2005,9,3]],"date-time":"2005-09-03T07:14:26Z","timestamp":1125731666000},"page":"3-9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Biases in observational studies of the effect of prenatal treatment for congenital toxoplasmosis"],"prefix":"10.1016","volume":"124","author":[{"given":"Rodolphe","family":"Thi\u00e9baut","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9riane","family":"Leroy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmadou","family":"Alioum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Binquet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwendoline","family":"Poizat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Rachid","family":"Salmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luuk","family":"Gras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Salamon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevi\u00e8ve","family":"Ch\u00eane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2005.07.019_bib1","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1056\/NEJM197405162902003","article-title":"Congenital toxoplasmosis. A prospective study of 378 pregnancies","volume":"290","author":"Desmonts","year":"1974","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib2","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/clinids\/18.1.38","article-title":"Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial","volume":"18","author":"McAuley","year":"1994","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib3","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0140-6736(90)91890-M","article-title":"What is known about the prevention of congenital toxoplasmosis?","volume":"336","author":"Jeannel","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib4","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0002-9378(99)70224-3","article-title":"Treatment of toxoplasmosis during pregnancy: a multicenter study of impact on fetal transmission and children's sequelae at age 1 year","volume":"180","author":"Foulon","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib5","doi-asserted-by":"crossref","unstructured":"European Multicentre Study on Congenital Toxoplasmosis. Effect of timing and type of treatment on the risk of mother to child transmission of Toxoplasma gondii. BJOG 2003;110:112\u201320.","DOI":"10.1046\/j.1471-0528.2003.02325.x"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib6","first-page":"171","article-title":"Prevention and treatment of congenital toxoplasmosis: organization protocol","volume":"56","author":"Vimercati","year":"2004","journal-title":"Minerva Ginecol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib7","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1177\/096914139600300406","article-title":"Screening for toxoplasmosis in pregnancy: what is the evidence of reducing a health problem?","volume":"3","author":"Eskild","year":"1996","journal-title":"J Med Screen"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib8","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1136\/bmj.318.7197.1511","article-title":"Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy","volume":"318","author":"Wallon","year":"1999","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib9","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1056\/NEJM198802043180502","article-title":"Prenatal management of 746 pregnancies at risk for congenital toxoplasmosis","volume":"318","author":"Daffos","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib10","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1017\/S095026880100560X","article-title":"Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol","volume":"127","author":"Gilbert","year":"2001","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib11","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/ije\/30.6.1303","article-title":"Effect of prenatal treatment on mother to child transmission of Toxoplasma gondii: retrospective cohort study of 554 mother\u2013child pairs in Lyon, France","volume":"30","author":"Gilbert","year":"2001","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib12","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/ije\/30.6.1309","article-title":"Effect of prenatal treatment on the risk of intracranial and ocular lesions in children with congenital toxoplasmosis","volume":"30","author":"Gras","year":"2001","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib13","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1093\/ije\/30.6.1314","article-title":"Commentary: little evidence of effective prenatal treatment against congenital toxoplasmosis\u2014the implications for testing in pregnancy","volume":"30","author":"Eskild","year":"2001","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib14","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/ije\/30.6.1315","article-title":"Commentary: efficacy of prenatal treatment for toxoplasmosis: a possibility that cannot be ruled out","volume":"30","author":"Thulliez","year":"2001","journal-title":"Int J Epidemiol"},{"year":"1998","series-title":"Modern epidemiology","author":"Rothman","key":"10.1016\/j.ejogrb.2005.07.019_bib15"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000263746","article-title":"In utero treatment of toxoplasmic fetopathy with the combination pyrimethamine\u2013sulfadiazine","volume":"8","author":"Couvreur","year":"1993","journal-title":"Fetal Diagn Ther"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib17","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/S0140-6736(98)08220-8","article-title":"Mother-to-child transmission of toxoplasmosis: risk estimates for clinical counselling","volume":"353","author":"Dunn","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib18","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/sim.1326","article-title":"Inference for a linear regression model with an interval-censored covariate","volume":"22","author":"Gomez","year":"2003","journal-title":"Stat Med"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib19","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/sim.1601","article-title":"Estimating linear regression models in the presence of a censored independent variable","volume":"23","author":"Austin","year":"2004","journal-title":"Stat Med"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib20","first-page":"296","article-title":"Prenatal diagnosis using polymerase chain reaction on amniotic fluid for congenital toxoplasmosis","volume":"97","author":"Romand","year":"2001","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0002-9394(14)72057-4","article-title":"Eye manifestations of congenital toxoplasmosis","volume":"122","author":"Mets","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib22","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/BF01701522","article-title":"Classification system and case definitions of Toxoplasma gondii infection in immunocompetent pregnant women and their congenitally infected offspring. European Research Network on Congenital Toxoplasmosis","volume":"15","author":"Lebech","year":"1996","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/oxfordjournals.aje.a009251","article-title":"Logistic regression when the outcome is measured with uncertainty","volume":"146","author":"Magder","year":"1997","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1136\/jms.9.3.135","article-title":"Congenital toxoplasmosis in the United Kingdom: to screen or not to screen?","volume":"9","author":"Gilbert","year":"2002","journal-title":"J Med Screen"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib25","series-title":"The Cochrane Library","article-title":"Timing and type of prenatal treatment for congenital toxoplasmosis (protocol for a cochrane review)","author":"Thi\u00e9baut","year":"2003"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib26","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1056\/NEJM199406303302604","article-title":"Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection","volume":"330","author":"Guerina","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib27","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1128\/JCM.36.10.2900-2906.1998","article-title":"Incidence of Toxoplasma gondii infection in 35, 940 pregnant women in Norway and pregnancy outcome for infected women","volume":"36","author":"Jenum","year":"1998","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib28","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1016\/S0140-6736(98)11281-3","article-title":"Feasibility of neonatal screening for toxoplasma infection in the absence of prenatal treatment","volume":"353","author":"Lebech","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib29","series-title":"Congenital and Perinatal Infections","first-page":"305","article-title":"Toxoplasmosis","author":"Gilbert","year":"2000"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1017\/S0950268801005775","article-title":"Low incidence of toxoplasma infection during pregnancy and in newborns in Sweden","volume":"127","author":"Evengard","year":"2001","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.ejogrb.2005.07.019_bib31","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1128\/JCM.39.5.1912-1916.2001","article-title":"Prevalence of congenital Toxoplasma gondii infection among newborns from the Poznan region of Poland: validation of a new combined enzyme immunoassay for Toxoplasma gondii-specific immunoglobulin A and immunoglobulin M antibodies","volume":"39","author":"Paul","year":"2001","journal-title":"J Clin Microbiol"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211505004161?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211505004161?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:14:18Z","timestamp":1759554858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211505004161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0301211505004161"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2005.07.019","relation":{},"ISSN":["0301-2115"],"issn-type":[{"type":"print","value":"0301-2115"}],"subject":[],"published":{"date-parts":[[2006,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biases in observational studies of the effect of prenatal treatment for congenital toxoplasmosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2005.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}