{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:37:12Z","timestamp":1770482232220,"version":"3.49.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.ejogrb.2008.08.004","type":"journal-article","created":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T04:46:55Z","timestamp":1225514815000},"page":"12-17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Influence of the magnesium aspartate hydrochloride administration to the maternal circuit on the aspartate concentration of the fetal circuit under in vitro perfusion of human placenta"],"prefix":"10.1016","volume":"142","author":[{"given":"A.","family":"Malek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Leiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2008.08.004_bib1","first-page":"109","article-title":"Perinatal magnesium metabolism: personal data and challenges for the 1990s","volume":"4","author":"Mimouni","year":"1991","journal-title":"Magnes Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib2","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/S0002-9378(12)90797-8","article-title":"Effects of magnesium and terbutaline on contractility and K+ uptake in isolated human uterine muscle","volume":"165","author":"Skajaa","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib3","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1159\/000293519","article-title":"The effect of magnesium on calcium uptake and contractility in the human myometrium","volume":"28","author":"Popper","year":"1989","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib4","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0022-3565(25)13019-X","article-title":"Tocolytic agents act on calcium channel current in single smooth muscle cells of pregnant rat uterus","volume":"253","author":"Ohya","year":"1990","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1139\/y92-064","article-title":"Fast Na+ channels in smooth muscle from pregnant rat uterus","volume":"70","author":"Sperelakis","year":"1992","journal-title":"Can J Pharmacol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib6","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0002-9378(95)91270-3","article-title":"Reduction of cerebral palsy with maternal MgSO4 treatment in newboms weighing 500\u20131000g","volume":"172","author":"Hauth","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib7","doi-asserted-by":"crossref","first-page":"223A","DOI":"10.1203\/00006450-199604001-01347","article-title":"Is magnesium neuroprotective to the fetus?","volume":"39","author":"Kumar","year":"1996","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib8","first-page":"284A","volume":"39","author":"Wiswell","year":"1996","journal-title":"Pediatr Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0002-9378(71)90330-9","article-title":"The effect of magnesium sulfate on anoxia and resuscitation in the neonate","volume":"109","author":"Dune","year":"1971","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib10","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/0006-8993(89)91188-8","article-title":"Magnesium protects against neurologic deficit after brain injury","volume":"482","author":"Mclntosh","year":"1989","journal-title":"Brain Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib11","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0304-3940(90)90569-U","article-title":"Magnesium reduces N-methyl-d-aspartate [NMDA]-mediated brain injury in perinatal rats","volume":"109","author":"McDonald","year":"1990","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/0006-8993(94)90357-3","article-title":"Protective effect of MgSO4 infusion on NMDA receptor binding characteristics during cerebral cortical hypoxia in the newborn piglet","volume":"644","author":"Hoffmann","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib13","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/00041552-199407000-00010","volume":"3","author":"Sibai","year":"1994","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib14","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/S0140-6736(02)08778-0","article-title":"Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial","volume":"359","author":"Altman","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib15","first-page":"359","article-title":"Magnesium and potassium aspartate during the third pregnancy trimester","volume":"42","author":"Lauletta","year":"1990","journal-title":"Minerva Ginecol (Italy)"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib16","first-page":"717","article-title":"Evaluation of the efficacy of the intravenous admixture of aspartate magnesium hydrochloride with beta-mimetics in the treatment of impending premature labor (letter)","volume":"108","author":"Spaetling","year":"1988","journal-title":"Rev Med Suisse Romande (Switzerland)"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib17","first-page":"283","article-title":"Usefulness of the addition of aspartate magnesium hydrochloride via intravenous route to beta mimetics in the treatment of threatened premature labor","volume":"108","author":"Francioli","year":"1988","journal-title":"Rev Med Suisse Romande (Switzerland)"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib18","first-page":"326","volume":"186","author":"Wischnik","year":"1982","journal-title":"Z Geburtshiife Perinatal (Germany)"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib19","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/00005072-197401000-00006","article-title":"Nature and extent of brain lesions in mice related to ingestion of monosodium glutamate: a light and electron microscope study","volume":"33","author":"Lemkey-Johnston","year":"1974","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib20","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1126\/science.164.3880.719","article-title":"Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate","volume":"164","author":"Oiney","year":"1969","journal-title":"Science"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib21","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/0002-9378(95)90336-4","article-title":"Transport of immunoglobulin G and its subclasses across the in vitro-perfused placenta","volume":"173","author":"Malek","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib22","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0021-9258(18)56807-1","article-title":"The estimation of antipyrine in biological materials","volume":"179","author":"Brodie","year":"1949","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0021-9673(00)97000-6","article-title":"Appraisal of four precolumn derivatization methods for the high-performance liquid chromatographic determination of free amino acids in biological materials","volume":"499","author":"F\u00fcrst","year":"1990","journal-title":"J Chromatogr"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib24","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1600-0897.1996.tb00172.x","article-title":"Evolution of matemo-fetal transport of immunoglobulins during human pregnancy","volume":"36","author":"Malek","year":"1996","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib25","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/107155769600300303","article-title":"Glucose consumption and lactate production of human placental tissue under different conditions of in vitro incubation","volume":"3","author":"Malek","year":"1996","journal-title":"J Soc Gynecol Invest"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib26","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0002-9378(96)70277-6","article-title":"Fetal ionized magnesium levels parallel maternal levels during magnesium sulfate therapy for preeclampsia","volume":"175","author":"Mason","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib27","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0002-9378(16)33027-7","article-title":"Effects of magnesium sulfate treatment on perinatal calcium metabolism I. Maternal and fetal response","volume":"134","author":"Cruikshank","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib28","first-page":"446","article-title":"Amniotic cavity accumulation of magnesium sulfate tocolysis","volume":"36","author":"Hankins","year":"1991","journal-title":"J Reprod Med"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib29","first-page":"2505","article-title":"Expression of inflammatory cytokines in placentas from women with preeclampsia","volume":"86","author":"Benyo","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib30","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1152\/physrev.1990.70.2.427","article-title":"Cytokines and endothelial cell biology","volume":"70","author":"Pober","year":"1990","journal-title":"Physiol Rev"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib31","first-page":"58","article-title":"Magnesium deficiency and endothelial dysfunction: is oxidative stress involved?","volume":"21","author":"Wolf","year":"2008","journal-title":"Magnes Res"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib32","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/0002-9378(74)90155-0","article-title":"Amino acid transport in human placental slices","volume":"120","author":"Schneider","year":"1974","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib33","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1471-0528.1979.tb11260.x","article-title":"Transfer of glutamic acid across the human placenta perfused in vitro","volume":"86","author":"Schneider","year":"1979","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ejogrb.2008.08.004_bib34","first-page":"87","article-title":"Metabolism of glutamic acid studied in the dually in vitro perfused human placental cotyledon","volume":"7","author":"Malek","year":"1993","journal-title":"Trophoblast Res"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211508003321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211508003321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:19:58Z","timestamp":1759555198000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211508003321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0301211508003321"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2008.08.004","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of the magnesium aspartate hydrochloride administration to the maternal circuit on the aspartate concentration of the fetal circuit under in vitro perfusion of human placenta","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2008.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}