{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:53:53Z","timestamp":1770504833104,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.ejogrb.2010.07.008","type":"journal-article","created":{"date-parts":[[2010,8,12]],"date-time":"2010-08-12T04:49:12Z","timestamp":1281588552000},"page":"52-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["The effects of acrylamide on sperm parameters and membrane integrity of epididymal spermatozoa in mice"],"prefix":"10.1016","volume":"153","author":[{"given":"Mohammad","family":"Kermani-Alghoraishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mortaza","family":"Anvari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Reza","family":"Talebi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omid","family":"Amini-Rad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahil","family":"Ghahramani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Mohsen","family":"Miresmaili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2010.07.008_bib0005","doi-asserted-by":"crossref","first-page":"4504","DOI":"10.1021\/jf030204+","article-title":"Chemistry, biochemistry, and safety of acrylamide. A review","volume":"51","author":"Friedman","year":"2003","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0010","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1515\/REVEH.1991.9.4.215","article-title":"Acrylamide and polyacrylamide: a review of production, use, environmental fate and neurotoxicity","volume":"9","author":"Smith","year":"1991","journal-title":"Rev Environ Health"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0015","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0027-5107(95)00037-J","article-title":"Acrylamide: a view of its genotoxicity and an assessment of heritable genetic risk","volume":"330","author":"Dearfield","year":"1995","journal-title":"Mutat Res"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0020","unstructured":"EIMS (Environmental information management system). IRIS toxicological review and summary documents for acrylamide. Meta Report Project 52015; 2002."},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0025","unstructured":"SNFA. Analytical Methodology and Survey Result for Acrylamide in Foods. Swedish National Food Administration, Uppsala, April 26, 2002. Available: http:\/\/www.slv.se."},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0030","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/419448a","article-title":"Acrylamide is formed in the Maillard reaction","volume":"419","author":"Mottram","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0035","doi-asserted-by":"crossref","first-page":"7012","DOI":"10.1021\/jf034649+","article-title":"Investigations of factors that influence the acrylamide content of heated foodstuffs","volume":"51","author":"Rydberg","year":"2003","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0040","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1017\/S0317167100119201","article-title":"A review of acrylamide neurotoxicity. Part II. Experimental animal neurotoxicity and pathologic mechanisms","volume":"1","author":"Spencer","year":"1974","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0045","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1006\/faat.1995.1112","article-title":"A lifetime oncogenicity study in rats with acrylamide","volume":"27","author":"Friedman","year":"1995","journal-title":"Fundam Appl Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0050","unstructured":"European Commission. Risk assessment of acrylamide. European Chemicals Bureau, Institute for Health and Consumer Protection, Joint Research Centre; 2000."},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0055","first-page":"144","article-title":"Genotoxicity and carcinogenicity of acrylamide: a critical review","volume":"2","author":"Carere","year":"2006","journal-title":"Ann Ist Super Sanita"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0060","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00290538","article-title":"Reproductive toxicity of acrylamide and related compounds in mice: effects on fertility and sperm morphology","volume":"59","author":"Sakamoto","year":"1986","journal-title":"Arch Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0065","first-page":"406","article-title":"Subchronic exposure to acrylamide affects reproduction and testis endocrine function of rats","volume":"14","author":"Song","year":"2008","journal-title":"Zhonghua Nan Ke Xue"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0070","first-page":"492","article-title":"Oral acrylamide affects the development and reproductive performance of male rats","volume":"13","author":"Wang","year":"2007","journal-title":"Zhonghua Nan Ke Xue"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0075","doi-asserted-by":"crossref","first-page":"103","DOI":"10.4142\/jvs.2005.6.2.103","article-title":"Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats","volume":"6","author":"Yang","year":"2005","journal-title":"J Vet Sci"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0080","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.reprotox.2004.10.006","article-title":"Toxicological effects of acrylamide on rat testicular gene expression profile","volume":"19","author":"Yang","year":"2005","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0085","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1530\/jrf.0.0700219","article-title":"Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics","volume":"70","author":"Jeyendran","year":"1984","journal-title":"J Reprod Fertil"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0090","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1365-2605.1987.tb00366.x","article-title":"Reassessment of the accuracy of traditional sperm characteristics and ATP in estimating the fertilising potential of human semen in vivo","volume":"10","author":"Comhaire","year":"1987","journal-title":"Int J Androl"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0095","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0093-691X(01)00461-7","article-title":"Adaptation of the hypoosmotic swelling test to assess functional integrity of stallion spermatozoal plasma membranes","volume":"55","author":"Nie","year":"2001","journal-title":"Theriogenology"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0100","series-title":"WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction","author":"World Health Organization","year":"1999"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0105","first-page":"77","article-title":"Application of vitality tests on asthenozoospermic semen from infertile men","volume":"3","author":"Khalili","year":"1999","journal-title":"Iran Biomed J"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0110","first-page":"171","article-title":"Evaluation of epididymal necrospermia following experimental chronic spinal cord injury in rat","volume":"5","author":"Talebi","year":"2007","journal-title":"Iran J Reprod Med"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0115","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1095\/biolreprod59.4.897","article-title":"Fertility of rat epididymal sperm after chemically and surgically induced sympathectomy","volume":"59","author":"Kempinas","year":"1998","journal-title":"Biol Reprod"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0120","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0890-6238(96)00028-7","article-title":"Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, dog: a consensus report","volume":"10","author":"Seed","year":"1996","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0125","series-title":"Handbook of the laboratory diagnosis and treatment of infertility","author":"Keel","year":"1990"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0130","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0890-6238(00)00066-6","article-title":"Relationship between acrylamide reproductive and neurotoxicity in male rats","volume":"14","author":"Tyl","year":"2000","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0135","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1262\/jrd.19191","article-title":"Leydig cell hyperplasia in an ENU-induced mutant mouse with germ cell depletion","volume":"54","author":"Khalaj","year":"2008","journal-title":"J Reprod Dev"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0140","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/BF00306048","article-title":"Changes in surface area and number of Leydig cells in relation to the 6 stages of the cycle of the human seminiferous epithelium","volume":"178","author":"Paniagua","year":"1988","journal-title":"Anat Embryol (Berl)"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0145","first-page":"159","article-title":"Toxicity of acrylamide on male reproduction","volume":"14","author":"Song","year":"2008","journal-title":"Zhonghua Nan Ke Xue"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0150","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0165-7992(86)90008-4","article-title":"Dominant lethal effects of acrylamide in male mice","volume":"173","author":"Shelby","year":"1986","journal-title":"Mutat Res"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0155","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/mutage\/15.2.133","article-title":"1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice","volume":"15","author":"Adler","year":"2000","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0160","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1021\/tx00025a014","article-title":"Characterization and quantitation of urinary metabolites of {1,2,3-13C}acrylamide in rats and mice using 13C nuclear magnetic resonance spectroscopy","volume":"5","author":"Sumner","year":"1992","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0165","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3109\/03602539608994018","article-title":"The metabolism and pharmacokinetics of acrylamide: implications for mechanisms of toxicity and human risk estimation","volume":"28","author":"Calleman","year":"1996","journal-title":"Drug Metab Rev"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0170","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0165-1218(90)90101-7","article-title":"Measurement of DNA breakage in specific germ-cell stages of male mice exposed to acrylamide, using an alkaline-elution procedure","volume":"242","author":"Sega","year":"1990","journal-title":"Mutat Res"},{"key":"10.1016\/j.ejogrb.2010.07.008_bib0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0890-6238(02)00078-3","article-title":"Effects of acrylamide on rodent reproductive performance","volume":"17","author":"Tyl","year":"2003","journal-title":"Reprod Toxicol"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211510003350?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211510003350?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:23:08Z","timestamp":1759555388000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211510003350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0301211510003350"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2010.07.008","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of acrylamide on sperm parameters and membrane integrity of epididymal spermatozoa in mice","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2010.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}