{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:34:44Z","timestamp":1786988084293,"version":"build-2736575974"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.ejogrb.2013.12.026","type":"journal-article","created":{"date-parts":[[2013,12,25]],"date-time":"2013-12-25T15:45:35Z","timestamp":1387986335000},"page":"106-110","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"special_numbering":"C","title":["Does cigarette smoking really have detrimental effects on outcomes of IVF?"],"prefix":"10.1016","volume":"174","author":[{"given":"Ozgur","family":"Cinar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar","family":"Dilbaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fusun","family":"Terzioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bensu","family":"Karahalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem","family":"Y\u00fccel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rukiye","family":"Turk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lale","family":"Taskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Kenan","family":"Kose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2013.12.026_bib0005","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1021\/es048690k","article-title":"Determination of 14 polycyclic aromatic hydrocarbons in mainstream smoke from domestic cigarettes","volume":"39","author":"Ding","year":"2005","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0010","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.2105\/AJPH.82.7.1023","article-title":"Carcinogens in tobacco smoke: benzo[a]pyrene from Canadian cigarettes and cigarette tobacco","volume":"82","author":"Kaiserman","year":"1992","journal-title":"Am J Public Health"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0015","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/humrep\/16.7.1382","article-title":"Effects of female and male smoking on success rates of IVF and gamete intra-fallopian transfer","volume":"16","author":"Klonoff-Cohen","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0020","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1093\/humrep\/dei080","article-title":"Sidestream smoking is equally as damaging as mainstream smoking on IVF outcomes","volume":"20","author":"Neal","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0025","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/humupd\/dmn046","article-title":"Effects of cigarette smoking upon clinical outcomes of assisted reproduction: a meta-analysis","volume":"15","author":"Waylen","year":"2009","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0030","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.fertnstert.2004.07.956","article-title":"Association of body mass index, age, and cigarette smoking with serum testosterone levels in cycling women undergoing in vitro fertilization","volume":"83","author":"Barbieri","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0035","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/j.1479-828X.1990.tb02024.x","article-title":"The effect of patient smoking habit on the outcome of IVF and GIFT treatment","volume":"30","author":"Harrison","year":"1990","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0040","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1210\/jc.2005-2515","article-title":"The influence of depression, body mass index, and smoking on serum inhibin B levels in late reproductive-aged women","volume":"91","author":"Lambert-Messerlian","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0045","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.fertnstert.2007.06.108","article-title":"Effect of a woman's smoking status on oocyte, zygote, and day 3 pre-embryo quality in in vitro fertilization and embryo transfer program","volume":"90","author":"Gruber","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0050","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ejogrb.2007.05.020","article-title":"Effect of cigarette smoke and alpha-tocopherol (vitamin E) on fertilization, cleavage, and embryo development rates in mice: an experimental in vitro fertilization mice model study","volume":"135","author":"Hassa","year":"2007","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0055","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/humrep\/del496","article-title":"Smoking, alcohol and caffeine in relation to ovarian age during the reproductive years","volume":"22","author":"Kinney","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0060","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0015-0282(16)54248-4","article-title":"The effect of cigarette smoking on ovarian function and early pregnancy outcome of in vitro fertilization treatment","volume":"55","author":"Pattinson","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0065","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1023\/A:1020496330424","article-title":"The effect of smoking on oocyte quality and hormonal parameters of patients undergoing in vitro fertilization-embryo transfer","volume":"16","author":"Weigert","year":"1999","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0070","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1093\/humrep\/del269","article-title":"The effect of female tobacco smoking on IVF outcomes","volume":"21","author":"Wright","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0075","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1093\/humrep\/13.8.2192","article-title":"Effect of smoking on ovarian reserve and ovarian stimulation in in-vitro fertilization and embryo transfer","volume":"13","author":"El-Nemr","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0080","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/01.ede.0000142137.39619.60","article-title":"Environmental tobacco smoke and pregnancy outcome","volume":"15","author":"Kharrazi","year":"2004","journal-title":"Epidemiology"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0085","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0015-0282(16)58219-3","article-title":"Influence of smoking on fertility in women attending an in vitro fertilization program","volume":"65","author":"Sterzik","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0090","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3109\/09513590.2010.491168","article-title":"Can serum oestradiol be a predictor of quality of oocytes and embryos, maturation of oocytes and pregnancy rate in ICSI cycles","volume":"27","author":"Ozdegirmenci","year":"2011","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0095","series-title":"WHO laboratory manual for the examination and processing of human semen","isbn-type":"print","year":"2010","ISBN":"https:\/\/id.crossref.org\/isbn\/9789241547789"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0100","first-page":"5","article-title":"Methods of embryo scoring in in vitro fertilization","volume":"4","author":"Baczkowski","year":"2004","journal-title":"Reprod Biol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0105","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1093\/humrep\/16.9.1970","article-title":"The Graduated Embryo Score (GES) predicts blastocyst formation and pregnancy rate from cleavage-stage embryos","volume":"16","author":"Fisch","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0110","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jpba.2004.01.009","article-title":"Measuring tobacco smoke exposure: quantifying nicotine\/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods","volume":"35","author":"Dhar","year":"2004","journal-title":"J Pharm Biomed Anal"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0115","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.3109\/09513590.2011.569784","article-title":"Does 75 IU difference improve the cycle performance in poor responders? Comparison of daily 375 versus 450IU gonadotrophin doses","volume":"27","author":"Dilbaz","year":"2011","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0120","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/humupd\/dmq033","article-title":"Effects of cigarette smoking on reproduction","volume":"17","author":"Dechanet","year":"2011","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0125","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1016\/j.juro.2011.06.061","article-title":"Effect of smoking status on seminal parameters and apoptotic markers in infertile men","volume":"186","author":"Tawadrous","year":"2011","journal-title":"J Urol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0130","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1439-0272.2004.00605.x","article-title":"Effects of paternal cigarette smoking on testicular function, sperm fertilizing capacity, embryonic development, and blastocyst capacity for implantation in rats","volume":"36","author":"Kapawa","year":"2004","journal-title":"Andrologia"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0135","first-page":"64","article-title":"The outcome of infertility treatment by in-vitro fertilisation in smoking and non-smoking women","volume":"9","author":"Crha","year":"2001","journal-title":"Cent Eur J Public Health"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0140","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ejogrb.2010.02.036","article-title":"Effect of female nargile smoking on in vitro fertilization outcome","volume":"150","author":"Hannoun","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0145","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.rbmo.2010.09.012","article-title":"High-quality embryos maintain high pregnancy rates in passive smokers but not in active smokers","volume":"22","author":"Ben-Haroush","year":"2011","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0150","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.fertnstert.2008.09.073","article-title":"Recent cigarette smoking and assisted reproductive technologies outcome","volume":"93","author":"Fuentes","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0155","article-title":"Gender differences in cigarette consumption in Turkey: evidence from the Global Adult Tobacco Survey","author":"Kilic","year":"2013","journal-title":"Health Policy"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0160","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1093\/humrep\/17.4.921","article-title":"Smoking induces oxidative stress inside the Graafian follicle","volume":"17","author":"Paszkowski","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0165","doi-asserted-by":"crossref","first-page":"54","DOI":"10.21101\/cejph.a3629","article-title":"Smoking practices in Jordanian people and their impact on semen quality and hormonal levels among adult men","volume":"19","author":"Al-Matubsi","year":"2011","journal-title":"Cent Eur J Public Health"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0170","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1439-0272.2005.00664.x","article-title":"Influence of cigarette smoking on spermatozoa via seminal plasma","volume":"37","author":"Arabi","year":"2005","journal-title":"Andrologia"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0175","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0890-6238(97)00100-7","article-title":"Cigarette smoke inhibits oocyte cumulus complex pick-up by the oviduct in vitro independent of ciliary beat frequency","volume":"12","author":"Knoll","year":"1998","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.ejogrb.2013.12.026_bib0180","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/humupd\/dml012","article-title":"The reproductive significance of human fallopian tube cilia","volume":"12","author":"Lyons","year":"2006","journal-title":"Hum Reprod Update"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211513006507?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211513006507?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:29:46Z","timestamp":1759555786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211513006507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":36,"alternative-id":["S0301211513006507"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2013.12.026","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does cigarette smoking really have detrimental effects on outcomes of IVF?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2013.12.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}