{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:58:03Z","timestamp":1788872283032,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Bayer Hispania"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.ejogrb.2014.10.034","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T14:48:18Z","timestamp":1414680498000},"page":"24-31","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Cost-effectiveness analysis in the treatment of heavy menstrual bleeding in Spain"],"prefix":"10.1016","volume":"184","author":[{"given":"J.","family":"Calaf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Lete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Canals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Crespo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Espin\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Crist\u00f3bal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ejogrb.2014.10.034_bib0005","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/humrep\/del478","article-title":"Can we achieve international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding?","volume":"22","author":"Fraser","year":"2007","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.ejogrb.2014.10.034_bib0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijgo.2010.11.011","article-title":"FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age","volume":"113","author":"Munro","year":"2011","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0015","series-title":"Heavy menstrual bleeding guideline","author":"National Collaborating Centre for Women's and Children's Health","year":"2007"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0020","series-title":"Consensus documents on menorrhagia SEGO","year":"2013"},{"issue":"4","key":"10.1016\/j.ejogrb.2014.10.034_bib0025","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0213-9111(02)71933-X","article-title":"What is an efficient health technology in Spain?","volume":"16","author":"Sacrist\u00e1n","year":"2002","journal-title":"Gac Sanit"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0030","series-title":"Consumer Price Index","author":"INE (National Statistics Institute)","year":"2013"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0035","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s10198-010-0244-4","article-title":"Spanish recommendations on economic evaluation of health technologies","volume":"11","author":"L\u00f3pez-Bastida","year":"2010","journal-title":"Eur J Health Econ"},{"issue":"2","key":"10.1016\/j.ejogrb.2014.10.034_bib0040","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1056\/NEJMoa1204724","article-title":"Levonorgestrel intrauterine system vs. medical therapy for menorrhagia","volume":"368","author":"Gupta","year":"2013","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.ejogrb.2014.10.034_bib0045","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S1701-2163(16)34151-2","article-title":"A Canadian: multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagia","volume":"31","author":"Endrikat","year":"2009","journal-title":"J Obstet Gynaecol Can"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0050","doi-asserted-by":"crossref","first-page":"c3929","DOI":"10.1136\/bmj.c3929","article-title":"Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients","volume":"341","author":"Middleton","year":"2010","journal-title":"Br Med J"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0055","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3109\/13625187.2011.591456","volume":"16","author":"Fraser","year":"2011","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"2","key":"10.1016\/j.ejogrb.2014.10.034_bib0060","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.contraception.2011.11.011","article-title":"Normalization of blood loss in women with heavy menstrual bleeding treated with an oral contraceptive containing estradiol valerate\/dienogest","volume":"86","author":"Fraser","year":"2012","journal-title":"Contraception"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0065","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.contraception.2006.03.024","article-title":"Cost-effectiveness of treatments for dysfunctional uterine bleeding in women who need contraception","volume":"74","author":"Blumenthal","year":"2006","journal-title":"Contraception"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0070","first-page":"492","article-title":"Randomised comparative trial of the levonorgestrel intrauterine system and norethisterone for the treatment of idiopathic menorraghia","volume":"104","author":"Irvine","year":"1998","journal-title":"Br J Obstet Gynaecol"},{"issue":"Suppl. 2","key":"10.1016\/j.ejogrb.2014.10.034_bib0075","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.3109\/13625187.2010.532999","article-title":"Efficacy of contraceptive methods: a review of the literature","volume":"15","author":"Mansour","year":"2010","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"1","key":"10.1016\/j.ejogrb.2014.10.034_bib0080","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ejogrb.2010.08.019","article-title":"Economic evaluation of the levonorgestrel-releasing intrauterine system for the treatment of dysfunctional uterine bleeding in Spain","volume":"154","author":"Lete","year":"2011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0085","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1017\/S0266462300012277","article-title":"A cost-utility analysis of abdominal hysterectomy vs. transcervical endometrial resection for the surgical treatment of menorrhagia","volume":"14","author":"Sculpher","year":"1998","journal-title":"Int J Technol Assess Health Care"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0090","unstructured":"General Council of Pharmaceutical Associations of Spain Database (CGCOF); 2013. Available from: http:\/\/www.portalfarma.com [Cited 29.05.14]."},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0095","series-title":"Spanish Health Costs Database eSALUD (2014)","author":"Gisbert","year":"2014"},{"issue":"5","key":"10.1016\/j.ejogrb.2014.10.034_bib0100","doi-asserted-by":"crossref","first-page":"479","DOI":"10.2165\/00019053-200017050-00006","article-title":"Handling uncertainty in cost-effectiveness models","volume":"17","author":"Briggs","year":"2000","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0105","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1093\/humrep\/del088","article-title":"A cost-utility analysis of hysterectomy, endometrial resection and ablation and medical therapy for menorrhagia","volume":"21","author":"You","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2014.10.034_bib0110","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1185\/030079907X199709","article-title":"Cost-utility of levonorgestrel intrauterine system compared with hysterectomy and second generation endometrial ablative techniques in managing patients with menorrhagia in the UK","volume":"23","author":"Clegg","year":"2007","journal-title":"Curr Med Res Opin"},{"issue":"2","key":"10.1016\/j.ejogrb.2014.10.034_bib0115","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jval.2012.11.011","article-title":"The cost-effectiveness of the levonorgestrel-releasing intrauterine system for the treatment of idiopathic heavy menstrual bleeding in the United States","volume":"16","author":"Ganz","year":"2013","journal-title":"Value Health"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211514005582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211514005582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:32:28Z","timestamp":1759555948000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211514005582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":23,"alternative-id":["S0301211514005582"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2014.10.034","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-effectiveness analysis in the treatment of heavy menstrual bleeding in Spain","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2014.10.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}