{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T06:10:50Z","timestamp":1759558250756,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.ejogrb.2015.01.011","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T02:30:23Z","timestamp":1421980223000},"page":"14-19","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Adjuvanted vaccines in pregnancy: no evidence for effect of the adjuvanted H1N1\/09 vaccination on occurrence of preeclampsia or intra-uterine growth restriction"],"prefix":"10.1016","volume":"187","author":[{"given":"Alies","family":"Coenders","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke K.","family":"Koopmans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Broekhuijsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henk","family":"Groen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janna M.A.","family":"Karstenberg-Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"van Goor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariette","family":"Groenewout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aren J.","family":"van Loon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marijke M.","family":"Faas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria G.","family":"van Pampus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ejogrb.2015.01.011_bib0155","first-page":"334","article-title":"H1N1 pandemic: life span considerations","volume":"20","author":"Blake","year":"2009","journal-title":"AACN Adv Crit Care"},{"issue":"11\u201312","key":"10.1016\/j.ejogrb.2015.01.011_bib0160","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.drudis.2009.02.009","article-title":"The path to a successful vaccine adjuvant \u2013 \u2018The long and winding road\u2019","volume":"14","author":"O\u2019Hagan","year":"2009","journal-title":"Drug Discov Today"},{"issue":"18","key":"10.1016\/j.ejogrb.2015.01.011_bib0165","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMra1000449","article-title":"Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection","volume":"362","author":"Bautista","year":"2010","journal-title":"N Engl J Med"},{"year":"2009","series-title":"Advisory letter vaccination against pandemic influenza A\/H1N1 2009: target groups and prioritisation","key":"10.1016\/j.ejogrb.2015.01.011_bib0170"},{"issue":"18","key":"10.1016\/j.ejogrb.2015.01.011_bib0175","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1016\/j.vaccine.2012.02.030","article-title":"Acceptance of vaccination during pregnancy: experience with 2009 influenza A (H1N1) in the Netherlands","volume":"30","author":"van Lier","year":"2012","journal-title":"Vaccine"},{"issue":"19","key":"10.1016\/j.ejogrb.2015.01.011_bib0180","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1056\/NEJMoa061741","article-title":"Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions","volume":"356","year":"2007","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.ejogrb.2015.01.011_bib0185","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S1473-3099(07)70113-5","article-title":"The case for maternal vaccination against pertussis","volume":"7","author":"Mooi","year":"2007","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.ejogrb.2015.01.011_bib0190","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1097\/GRF.0b013e318181dde1","article-title":"Vaccines for pertussis and influenza: recommendations for use in pregnancy","volume":"51","author":"Gall","year":"2008","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2015.01.011_bib0195","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/epirev\/mxj002","article-title":"Delivering influenza vaccine to pregnant women","volume":"28","author":"Naleway","year":"2006","journal-title":"Epidemiol Rev"},{"issue":"1","key":"10.1016\/j.ejogrb.2015.01.011_bib0200","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0002-9378(98)70254-6","article-title":"Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis","volume":"179","author":"Sacks","year":"1998","journal-title":"Am J Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.ejogrb.2015.01.011_bib0205","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/S0015-0282(02)02976-X","article-title":"Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycle","volume":"77","author":"Veenstra van Nieuwenhoven","year":"2002","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ejogrb.2015.01.011_bib0210","doi-asserted-by":"crossref","first-page":"e86355","DOI":"10.1371\/journal.pone.0086355","article-title":"Porphyromonas Gingivalis and E. Coli induce different cytokine production patterns in pregnant women","volume":"9","author":"Faas","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ejogrb.2015.01.011_bib0215","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/0192623313482205","article-title":"The placenta in toxicology. part II: systemic and local immune adaptations in pregnancy","volume":"42","author":"Svensson-Arvelund","year":"2014","journal-title":"Toxicol Pathol"},{"issue":"12","key":"10.1016\/j.ejogrb.2015.01.011_bib0220","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1586\/erv.10.133","article-title":"New adjuvanted vaccines in pregnancy: what is known about their safety?","volume":"9","author":"Herberts","year":"2010","journal-title":"Expert Rev Vaccines"},{"issue":"1","key":"10.1016\/j.ejogrb.2015.01.011_bib0225","doi-asserted-by":"crossref","first-page":"IX","DOI":"10.3109\/10641950109152635","article-title":"The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the international society for the study of hypertension in pregnancy (ISSHP)","volume":"20","author":"Brown","year":"2001","journal-title":"Hypertens Pregnancy"},{"issue":"2","key":"10.1016\/j.ejogrb.2015.01.011_bib0230","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/00003081-200606000-00004","article-title":"Fetal growth compromise: definitions, standards, and classification","volume":"49","author":"Maulik","year":"2006","journal-title":"Clin Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.ejogrb.2015.01.011_bib0235","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.bpobgyn.2011.01.007","article-title":"Risk factors and causal models","volume":"25","author":"Trogstad","year":"2011","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"2","key":"10.1016\/j.ejogrb.2015.01.011_bib0240","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/01.grf.0000160316.67359.3d","article-title":"Long-term outcomes after preeclampsia","volume":"48","author":"van Pampus","year":"2005","journal-title":"Clin Obstet Gynecol"},{"issue":"9741","key":"10.1016\/j.ejogrb.2015.01.011_bib0245","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Pre-eclampsia","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.ejogrb.2015.01.011_bib0250","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1053\/j.semperi.2008.02.004","article-title":"Non-placental causes of intrauterine growth restriction","volume":"32","author":"Hendrix","year":"2008","journal-title":"Semin Perinatol"},{"issue":"4","key":"10.1016\/j.ejogrb.2015.01.011_bib0255","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1056\/NEJMoa1207210","article-title":"Risk of fetal death after pandemic influenza virus infection or vaccination","volume":"368","author":"Haberg","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2015.01.011_bib0260","doi-asserted-by":"crossref","first-page":"e2794","DOI":"10.1136\/bmj.e2794","article-title":"Vaccination against pandemic A\/H1N1 2009 influenza in pregnancy and risk of fetal death: cohort study in denmark","volume":"344","author":"Pasternak","year":"2012","journal-title":"Br Med J"},{"key":"10.1016\/j.ejogrb.2015.01.011_bib0265","doi-asserted-by":"crossref","first-page":"f393","DOI":"10.1136\/bmj.f393","article-title":"Influenza A\/H1N1 MF59 adjuvanted vaccine in pregnant women and adverse perinatal outcomes: multicentre study","volume":"346","author":"Rubinstein","year":"2013","journal-title":"Br Med J"},{"issue":"8","key":"10.1016\/j.ejogrb.2015.01.011_bib0270","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/OGX.0b013e3182331028","article-title":"A critical review of early-onset and late-onset preeclampsia","volume":"66","author":"Raymond","year":"2011","journal-title":"Obstet Gynecol Surv"},{"issue":"2","key":"10.1016\/j.ejogrb.2015.01.011_bib0275","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1001\/jama.2012.6131","article-title":"Risk of adverse fetal outcomes following administration of a pandemic influenza A(H1N1) vaccine during pregnancy","volume":"308","author":"Pasternak","year":"2012","journal-title":"J Am Med Assoc"},{"issue":"13","key":"10.1016\/j.ejogrb.2015.01.011_bib0280","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1111\/j.1471-0528.2012.03470.x","article-title":"Vaccination against H1N1 influenza with pandemrix((R)) during pregnancy and delivery outcome: a swedish register study","volume":"119","author":"Kallen","year":"2012","journal-title":"BJOG"},{"issue":"37","key":"10.1016\/j.ejogrb.2015.01.011_bib0285","doi-asserted-by":"crossref","first-page":"6358","DOI":"10.1016\/j.vaccine.2011.04.114","article-title":"Pregnancy and safety outcomes in women vaccinated with an AS03-adjuvanted split virion H1N1 (2009) pandemic influenza vaccine during pregnancy: a prospective cohort study","volume":"29","author":"Tavares","year":"2011","journal-title":"Vaccine"},{"issue":"7","key":"10.1016\/j.ejogrb.2015.01.011_bib0290","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.vaccine.2009.11.077","article-title":"Exposure to MF59-adjuvanted influenza vaccines during pregnancy\u2014a retrospective analysis","volume":"28","author":"Tsai","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.ejogrb.2015.01.011_bib0295","doi-asserted-by":"crossref","first-page":"g3361","DOI":"10.1136\/bmj.g3361","article-title":"Evaluation of safety of A\/H1N1 pandemic vaccination during pregnancy: cohort study","volume":"348","author":"Trotta","year":"2014","journal-title":"Br Med J"},{"issue":"3","key":"10.1016\/j.ejogrb.2015.01.011_bib0300","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ajog.2012.07.007","article-title":"Safety of MF59-adjuvanted A\/H1N1 influenza vaccine in pregnancy: a comparative cohort study","volume":"207","author":"Heikkinen","year":"2012","journal-title":"Am J Obstet Gynecol"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211515000202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211515000202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:33:40Z","timestamp":1759556020000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211515000202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":30,"alternative-id":["S0301211515000202"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2015.01.011","relation":{},"ISSN":["0301-2115"],"issn-type":[{"type":"print","value":"0301-2115"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adjuvanted vaccines in pregnancy: no evidence for effect of the adjuvanted H1N1\/09 vaccination on occurrence of preeclampsia or intra-uterine growth restriction","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2015.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}