{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T00:28:52Z","timestamp":1759624132095,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.ejogrb.2015.06.029","type":"journal-article","created":{"date-parts":[[2015,7,10]],"date-time":"2015-07-10T09:10:20Z","timestamp":1436519420000},"page":"5-9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Nerve-sparing abdominal radical trachelectomy: a novel concept to preserve uterine branches of pelvic nerves"],"prefix":"10.1016","volume":"193","author":[{"given":"Satoru","family":"Kyo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunari","family":"Mizumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Takakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Katagiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2015.06.029_bib0175","first-page":"69","article-title":"Global cancer statistics","volume":"61","author":"Jemal","year":"2011","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0180","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1111\/j.1471-0528.1997.tb10946.x","article-title":"Abdominal radical trachelectomy: a new surgical technique for the conservative management of cervical carcinoma","volume":"104","author":"Smith","year":"1997","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0185","first-page":"255","article-title":"Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma","volume":"111","author":"Diaz","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0190","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ygyno.2008.04.027","article-title":"Radical vaginal trachelectomy vs. radical hysterectomy for small early stage cervical cancer: a matched case\u2013control study","volume":"110","author":"Beiner","year":"2008","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0195","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ygyno.2007.03.009","article-title":"Oncological safety of laparoscopic-assisted vaginal radical trachelectomy (LARVT or Dargent's operation): a comparative study with laparoscopic-assisted vaginal radical hysterectomy (LARVH)","volume":"106","author":"Marchiole","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0200","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1093\/humrep\/det118","article-title":"Reproductive and obstetric outcomes after radical abdominal trachelectomy for early-stage cervical cancer in a series of 31 pregnancies","volume":"28","author":"Nishio","year":"2013","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0205","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1097\/IGC.0b013e3182230294","article-title":"Fertility outcome after radical vaginal trachelectomy: a prospective study of 212 patients","volume":"21","author":"Speiser","year":"2011","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0210","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1038\/bjc.2013.656","article-title":"Comparisons of vaginal and abdominal radical trachelectomy for early-stage cervical cancer: preliminary results of a multi-center research in China","volume":"109","author":"Cao","year":"2013","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0215","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ygyno.2013.06.010","article-title":"Surgical, oncological, and obstetrical outcomes after abdominal radical trachelectomy \u2013 a systematic literature review","volume":"131","author":"Pareja","year":"2013","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0220","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S1470-2045(10)70084-X","article-title":"Fertility-sparing surgery in patients with cervical cancer","volume":"12","author":"Rob","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0225","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1097\/IGC.0b013e318296034e","article-title":"Expanding the indications for radical trachelectomy: a report on 29 patients with stage IB1 tumors measuring 2\u20134 centimeters","volume":"23","author":"Wethington","year":"2013","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0230","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ygyno.2013.07.079","article-title":"Abdominal radical trachelectomy: is it safe for IB1 cervical cancer with tumors \u22652cm","volume":"131","author":"Li","year":"2013","journal-title":"Gynecol Oncol"},{"issue":"2 Suppl.","key":"10.1016\/j.ejogrb.2015.06.029_bib0235","doi-asserted-by":"crossref","first-page":"S111","DOI":"10.1016\/j.ygyno.2008.07.028","article-title":"Update on abdominal radical trachelectomy","volume":"111","author":"Cibula","year":"2008","journal-title":"Gynecol Oncol"},{"year":"1983","series-title":"Clinical gynecological urology","author":"Amussen","key":"10.1016\/j.ejogrb.2015.06.029_bib0240"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0245","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0950-3552(98)80022-9","article-title":"An improved radical hysterectomy with fewer urological complications and with no loss of therapeutic results for invasive cervical cancer","volume":"2","author":"Sakamoto","year":"1988","journal-title":"Baillieres Clin Obstet Gynaecol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0250","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0002-9378(91)90614-W","article-title":"Dissection of the cardinal ligament in radical hysterectomy for cervical cancer with emphasis on the lateral ligament","volume":"164","author":"Yabuki","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0255","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1046\/j.0022-7722.2002.00023.x","article-title":"Does the cardinal ligament of the uterus contain a nerve that should be preserved in radical hysterectomy?","volume":"77","author":"Kato","year":"2002","journal-title":"Anat Sci Int"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0260","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0002-9378(98)70533-2","article-title":"Liposuction-assisted nerve-sparing extended radical hysterectomy: oncologic rationale, surgical anatomy, and feasibility study","volume":"178","author":"H\u00f6ckel","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0265","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1136\/ijgc-00009577-200105000-00003","article-title":"A nerve-sparing radical hysterectomy: guidelines and feasibility in Western patients","volume":"11","author":"Trimbos","year":"2001","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1447-0756.2000.tb01192.x","article-title":"New method to prevent bladder dysfunction after radical hysterectomy for uterine cervical cancer","volume":"26","author":"Kuwabara","year":"2000","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0275","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1097\/IGC.0000000000000114","article-title":"Nerve-sparing radical abdominal trachelectomy versus nerve-sparing radical hysterectomy in early-stage (FIGO IA2-IB) cervical cancer: a comparative study on feasibility and outcome","volume":"24","author":"van Gent","year":"2014","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0280","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1006\/gyno.1999.5723","article-title":"Radical hysterectomy: an anatomic evaluation of parametrial dissection","volume":"77","author":"Yabuki","year":"2000","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0285","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ygyno.2007.08.076","article-title":"Anatomic identification and functional outcomes of the nerve sparing Okabayashi radical hysterectomy","volume":"107","author":"Fujii","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0290","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1006\/gyno.1996.0251","article-title":"A new proposal for radical hysterectomy","volume":"62","author":"Yabuki","year":"1996","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0295","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1600-0897.1995.tb00904.x","article-title":"Presence of activated macrophages in a murine model of early embryo loss","volume":"33","author":"Haddad","year":"1995","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0300","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0165-5728(00)00299-X","article-title":"Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy","volume":"109","author":"Piccinni","year":"2000","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0305","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/346274a0","article-title":"Mast cells as a source of both preformed and immunologically inducible TNF-alpha\/cachectin","volume":"346","author":"Gordon","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.32604\/biocell.2004.28.001","article-title":"Uterine mast cells: a new hypothesis to understand how we are born","volume":"28","author":"Rudolph","year":"2004","journal-title":"Biocell"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0315","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1152\/ajplegacy.1952.170.3.522","article-title":"Inhibition of decidual cell formation in the pseudopregnant rat by histamine antagonists","volume":"170","author":"Shelesnyak","year":"1952","journal-title":"Am J Physiol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0320","first-page":"93","article-title":"Histamine content and mast cells distribution in mouse uterus: the effect of sexual hormones, gestation and labor","volume":"36","author":"Padilla","year":"1990","journal-title":"Cell Mol Biol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0325","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.prostaglandins.2009.09.004","article-title":"Uterine autonomic nerve innervation plays a crucial role in regulating rat uterine mast cell functions during embryo implantation","volume":"90","author":"Yuan","year":"2009","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0330","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1096\/fj.02-1008com","article-title":"Histamine enhances TGF-beta1-mediated suppression of Th2 responses","volume":"17","author":"Kunzmann","year":"2003","journal-title":"FASEB J"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0335","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1600-0897.1998.tb00368.x","article-title":"Early recognition of pregnancy by the maternal immune system","volume":"39","author":"Kelemen","year":"1998","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2015.06.029_bib0340","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1189\/jlb.1102566","article-title":"Predominance of Th2-promoting dendritic cells in early human pregnancy decidua","volume":"74","author":"Miyazaki","year":"2003","journal-title":"J Leukoc Biol"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211515002201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211515002201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:34:07Z","timestamp":1759556047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211515002201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":34,"alternative-id":["S0301211515002201"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2015.06.029","relation":{},"ISSN":["0301-2115"],"issn-type":[{"type":"print","value":"0301-2115"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nerve-sparing abdominal radical trachelectomy: a novel concept to preserve uterine branches of pelvic nerves","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2015.06.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}