{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:24:23Z","timestamp":1780730663693,"version":"3.54.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.ejogrb.2016.03.011","type":"journal-article","created":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T16:42:54Z","timestamp":1458232974000},"page":"108-112","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Comparison of plasma fetuin A levels in patients with early-onset pre-eclampsia vs late-onset pre-eclampsia"],"prefix":"10.1016","volume":"200","author":[{"given":"C.Y.","family":"Sanhal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Can Kavcar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Yucel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Erkenekl\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Erkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Uygur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2016.03.011_bib0205","series-title":"UpToDate","article-title":"Preeclampsia: clinical features and diagnosis","author":"August","year":"2016"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejogrb.2013.05.005","article-title":"Global and regional estimates of preeclampsia and eclampsia: a systematic review","volume":"170","author":"Abalos","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0215","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/HYPERTENSIONAHA.108.117358","article-title":"Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease","volume":"52","author":"Valensise","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0220","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1081\/PRG-120021060","article-title":"Subclassification of preeclampsia","volume":"22","author":"von Dadelszen","year":"2003","journal-title":"Hypertens Pregnancy"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0225","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0140-6736(05)17987-2","article-title":"Pre-eclampsia","volume":"365","author":"Sibai","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0230","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ajog.2006.01.014","article-title":"Placental angiogenic growth factors and uterine artery Doppler findings for characterization of different subsets in preeclampsia and in isolated intrauterine growth restriction","volume":"195","author":"Crispi","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0235","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/00024382-200115030-00004","article-title":"Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan","volume":"15","author":"Ombrellino","year":"2001","journal-title":"Shock"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0240","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1172\/JCI17202","article-title":"The serum protein alpha 2-Heremans\u2013Schmid glycoprotein\/fetuin-A is a systemically acting inhibitor of ectopic calcification","volume":"112","author":"Schafer","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0245","doi-asserted-by":"crossref","first-page":"e19228","DOI":"10.1371\/journal.pone.0019228","article-title":"Serum fetuin-A associates with type 2 diabetes and insulin resistance in Chinese adults","volume":"6","author":"Song","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0250","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3109\/15412555.2012.727922","article-title":"Fetuin-A is associated with disease severity and exacerbation frequency in patients with COPD","volume":"10","author":"Minas","year":"2013","journal-title":"COPD"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0255","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/MAJ.0000000000000195","article-title":"Decreased serum fetuin-A levels and active inflammatory bowel disease","volume":"348","author":"Ma","year":"2014","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0260","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1189\/jlb.1112603","article-title":"A leading role for the immune system in the pathophysiology of preeclampsia","volume":"94","author":"Laresgoiti-Servitje","year":"2013","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0265","first-page":"1122","article-title":"Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists\u2019 Task Force on Hypertension in Pregnancy","volume":"122","author":"American College of Obstetricians and Gynecologists","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0270","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.mehy.2014.08.001","article-title":"Pre-eclampsia renamed and reframed: intra-abdominal hypertension in pregnancy","volume":"83","author":"Sawchuck","year":"2014","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0275","first-page":"466","article-title":"Pre-eclampsia part 1: current understanding of its pathophysiology","volume":"10","author":"Chaiworapongsa","year":"2014","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0280","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1471-0528.2004.00071.x","article-title":"Is pre-eclampsia more than one disease?","volume":"111","author":"Vatten","year":"2004","journal-title":"BJOG"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0285","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.2353\/ajpath.2008.070629","article-title":"Preeclampsia-related inflammatory cytokines regulate interleukin-6 expression in human decidual cells","volume":"172","author":"Lockwood","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0290","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1042\/BST20110672","article-title":"Is inflammation the cause of pre-eclampsia?","volume":"39","author":"Ramma","year":"2011","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0295","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2172-11-59","article-title":"Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array","volume":"11","author":"Szarka","year":"2010","journal-title":"BMC Immunol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0300","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jri.2015.05.007","article-title":"Increased circulating interleukin-17 levels in preeclampsia","volume":"112","author":"Molvarec","year":"2015","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0305","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1161\/CIRCRESAHA.110.234260","article-title":"Fetuin-A regulation of calcified matrix metabolism","volume":"108","author":"Jahnen-Dechent","year":"2011","journal-title":"Circ Res"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0310","doi-asserted-by":"crossref","first-page":"3986","DOI":"10.1016\/j.bpj.2010.10.030","article-title":"Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on fetuin-A controlled calcification inhibition","volume":"99","author":"Heiss","year":"2010","journal-title":"Biophys J"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0315","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S8756-3282(99)00251-3","article-title":"Relationships between bone protein and mineral in developing porcine long bone and calvaria","volume":"26","author":"Sodek","year":"2000","journal-title":"Bone"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0320","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/sj.jid.5701119","article-title":"Fetuin-A: a major fetal serum protein that promotes wound closure and scarless healing","volume":"128","author":"Wang","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0325","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1111\/j.2042-7158.2012.01561.x","article-title":"Role of fetuin-A in atherosclerosis associated with diabetic patients","volume":"64","author":"Singh","year":"2012","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0330","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/j.jacc.2012.01.038","article-title":"The association of fetuin-A with cardiovascular disease mortality in older community-dwelling adults: the Rancho Bernardo study","volume":"59","author":"Laughlin","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0335","first-page":"191","article-title":"Serum fetuin A concentrations in patients with acute pancreatitis","volume":"56","author":"Kusnierz-Cabala","year":"2010","journal-title":"Clin Lab"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0340","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S0140-6736(03)12710-9","article-title":"Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study","volume":"361","author":"Ketteler","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0345","doi-asserted-by":"crossref","first-page":"e46374","DOI":"10.1371\/journal.pone.0046374","article-title":"Jacalin bound plasma O-glycoproteome and reduced sialylation of alpha 2-HS glycoprotein (A2HSG) in rheumatoid arthritis patients","volume":"7","author":"Saroha","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0350","doi-asserted-by":"crossref","first-page":"e16945","DOI":"10.1371\/journal.pone.0016945","article-title":"A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation","volume":"6","author":"Li","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0355","series-title":"Acute phase proteins: regulation and functions of acute phase proteins","first-page":"329","author":"Wang","year":"2011"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0360","doi-asserted-by":"crossref","first-page":"625","DOI":"10.2174\/156652412800620039","article-title":"Anti-inflammatory role of fetuin-A in injury and infection","volume":"12","author":"Wang","year":"2012","journal-title":"Curr Mol Med"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0365","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/BF00398343","article-title":"Fetuin: an acute phase protein in cattle","volume":"162","author":"Dziegielewska","year":"1992","journal-title":"J Comp Physiol B"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0370","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/SHK.0b013e3181997173","article-title":"HMGB1 is markedly elevated within 6hours of mechanical trauma in humans","volume":"32","author":"Peltz","year":"2009","journal-title":"Shock"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0375","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1161\/CIRCULATIONAHA.108.814418","article-title":"Plasma fetuin-A levels and the risk of myocardial infarction and ischemic stroke","volume":"118","author":"Weikert","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0380","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.atherosclerosis.2009.07.032","article-title":"Fetuin-A and CD40 L plasma levels in acute ischemic stroke: differences in relation to TOAST subtype and correlation with clinical and laboratory variables","volume":"208","author":"Tuttolomondo","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0385","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/hr.2009.79","article-title":"Preeclampsia is associated with decreased serum alpha(2)-HS glycoprotein (fetuin-A) concentration","volume":"32","author":"Molvarec","year":"2009","journal-title":"Hypertens Res"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0390","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajog.2012.10.872","article-title":"Effects of increased fetuin-A in human trophoblast cells and associated pregnancy outcomes","volume":"207","author":"Gomez","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0395","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3858\/emm.2011.43.7.047","article-title":"Discovery of the serum biomarker proteins in severe preeclampsia by proteomic analysis","volume":"43","author":"Park","year":"2011","journal-title":"Exp Mol Med"},{"key":"10.1016\/j.ejogrb.2016.03.011_bib0400","first-page":"1","article-title":"Maternal plasma fetuin-A concentration is lower in patients who subsequently developed preterm preeclampsia than in uncomplicated pregnancy: a longitudinal study","volume":"29","author":"Chaemsaithong","year":"2014","journal-title":"J Matern Fetal Neonatal Med"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211516301002?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211516301002?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T21:23:27Z","timestamp":1769808207000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211516301002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":40,"alternative-id":["S0301211516301002"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2016.03.011","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of plasma fetuin A levels in patients with early-onset pre-eclampsia vs late-onset pre-eclampsia","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2016.03.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}