{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:28:38Z","timestamp":1790634518381,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ejogrb.2016.10.016","type":"journal-article","created":{"date-parts":[[2016,11,2]],"date-time":"2016-11-02T14:18:03Z","timestamp":1478096283000},"page":"121-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Coital pain in the elderly: could a low dose estriol gel thrill the vulvar vestibule?"],"prefix":"10.1016","volume":"207","author":[{"given":"Filippo","family":"Murina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Graziottin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Felice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Di Francesco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.ejogrb.2016.10.016_bib0005","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1097\/GME.0b013e3182a122c2","article-title":"Management of symptomatic vulvovaginal atrophy: 2013 position statement of The North American Menopause Society","volume":"20","year":"2013","journal-title":"Menopause"},{"issue":"12","key":"10.1016\/j.ejogrb.2016.10.016_bib0010","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1007\/s11606-008-0820-9","article-title":"Correlates of sexual satisfaction among sexually active postmenopausal women in the Women\u2019s Health Initiative Observational Study","volume":"23","author":"McCall-Hosenfeld","year":"2008","journal-title":"J Gen Intern Med"},{"issue":"2","key":"10.1016\/j.ejogrb.2016.10.016_bib0015","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1743-6109.2007.00685.x","article-title":"The frequency of sexual intercourse reported by women: a review of community-based studies and factors limiting their conclusions","volume":"5","author":"Schneidewind-Skibbe","year":"2008","journal-title":"J Sex Med"},{"issue":"3","key":"10.1016\/j.ejogrb.2016.10.016_bib0020","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.maturitas.2014.07.013","article-title":"Genitourinary syndrome of menopause: new terminology for vulvovaginal atrophy from the International Society for the Study of Women\u2019s Sexual Health and The North American Menopause Society","volume":"79","author":"Portman","year":"2014","journal-title":"Maturitas"},{"issue":"4","key":"10.1016\/j.ejogrb.2016.10.016_bib0025","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1095\/biolreprod.104.030023","article-title":"Estrogen regulates vaginal sensory and autonomic nerve density in the rat","volume":"71","author":"Ting","year":"2004","journal-title":"Biol Reprod"},{"issue":"6","key":"10.1016\/j.ejogrb.2016.10.016_bib0030","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/gme.0b013e31823b8983","article-title":"Systemic and topical hormone therapies reduce vaginal innervation density in postmenopausal women","volume":"19","author":"Griebling","year":"2012","journal-title":"Menopause"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0035","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1111\/j.1743-6109.2012.02771.x","article-title":"Biopsychosocial predictors of postmenopausal dyspareunia: the role of steroid hormones, vulvovaginal atrophy, cognitive-emotional factors, and dyadic adjustment","volume":"9","author":"Kao","year":"2012","journal-title":"J Sex Med"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0040","series-title":"Women\u2019s sexual function and dysfunction: study diagnosis and treatment","author":"Goldstein","year":"2005"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0045","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/S0002-9378(12)90732-2","article-title":"Vulvar vestibulitis syndrome: an overview","volume":"165","author":"Marinoff","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0050","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0306-4522(00)00549-2","article-title":"Sympathetic hyperinnervation of the uterus in the estrogen receptor alpha knock-out mouse","volume":"103","author":"Zoubina","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0055","first-page":"963","article-title":"Postpartum dyspareunia\u2014an unexplored problem","volume":"44","author":"Goetsch","year":"1999","journal-title":"J Reprod Med"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0060","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/0092623X.2011.569641","article-title":"Challenging atrophied perspectives on postmenopausal dyspareunia: a systematic description and synthesis of pain characteristics","volume":"38","author":"Kao","year":"2012","journal-title":"J Sex Marital Ther"},{"issue":"5","key":"10.1016\/j.ejogrb.2016.10.016_bib0065","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1210\/er.2007-0001","article-title":"The complex role of estrogens in inflammation","volume":"28","author":"Straub","year":"2007","journal-title":"Endocr Rev"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0070","first-page":"772","article-title":"2003 ISSVD terminology and classification of vulvodynia: a historical perspective","volume":"49","author":"Moyal-Barracco","year":"2004","journal-title":"J Reprod Med"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0075","series-title":"Vulvodynia tips and tricks","author":"Graziottin","year":"2011"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0080","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/AOG.0b013e3182a5f25f","article-title":"Histopathologic characteristics of menopausal vestibulodynia","volume":"122","author":"Leclair","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2016.10.016_bib0085","first-page":"281","article-title":"Postmenopausal vaginal atrophy: evaluation of treatment with local estrogen therapy","volume":"6","author":"Minkin","year":"2013","journal-title":"Int J Womens Health"},{"issue":"10","key":"10.1016\/j.ejogrb.2016.10.016_bib0090","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1517\/17425247.2011.600119","article-title":"Vaginal gel drug delivery systems: understanding rheological characteristics and performance","volume":"8","author":"Yu","year":"2011","journal-title":"Expert Opin Drug Deliv"},{"issue":"4","key":"10.1016\/j.ejogrb.2016.10.016_bib0095","first-page":"CD001500","article-title":"Local oestrogen for vaginal atrophy in postmenopausal women","volume":"18","author":"Suckling","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"issue":"10","key":"10.1016\/j.ejogrb.2016.10.016_bib0100","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/gme.0b013e3182518e9a","article-title":"The therapeutic effect of a new ultra low concentration estriol gel formulation (0.005% estriol vaginal gel) on symptoms and signs of postmenopausal vaginal atrophy: results from a pivotal phase III study","volume":"19","author":"Cano","year":"2012","journal-title":"Menopause"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211516309642?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211516309642?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:38:43Z","timestamp":1759556323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211516309642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":20,"alternative-id":["S0301211516309642"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2016.10.016","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coital pain in the elderly: could a low dose estriol gel thrill the vulvar vestibule?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2016.10.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}