{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T16:02:16Z","timestamp":1779811336785,"version":"3.53.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.ejogrb.2017.01.016","type":"journal-article","created":{"date-parts":[[2017,1,18]],"date-time":"2017-01-18T13:30:16Z","timestamp":1484746216000},"page":"342-347","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Intrauterine insemination\u2014No more Mr. N.I.C.E. guy?"],"prefix":"10.1016","volume":"210","author":[{"given":"Minna E.","family":"Geisler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Ledwidge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Bermingham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"McAuliffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moya B.","family":"McMenamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Waterstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"October (10)","key":"10.1016\/j.ejogrb.2017.01.016_bib0005","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1093\/humrep\/deu175","article-title":"Assisted reproductive technology in Europe, 2010: results generated from European registers by ESHRE","volume":"29","author":"Kupka","year":"2014","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.ejogrb.2017.01.016_bib0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.fertnstert.2008.09.058","article-title":"Predictive factors for pregnancy after intrauterine insemination (IUI): an analysis of 1038 cycles and a review of the literature","volume":"93","author":"Merviel","year":"2010","journal-title":"Fertil Steril"},{"issue":"July (7)","key":"10.1016\/j.ejogrb.2017.01.016_bib0015","doi-asserted-by":"crossref","first-page":"500","DOI":"10.3109\/09513590903367036","article-title":"Cumulative clinical pregnancy rates after COH and IUI in subfertile couples","volume":"26","author":"Farhi","year":"2010","journal-title":"Gynecol Endocrinol"},{"issue":"1","key":"10.1016\/j.ejogrb.2017.01.016_bib0020","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0015-0282(00)01641-1","article-title":"Controlled ovarian hyperstimulation and intrauterine insemination for treatment of unexplained infertility should be limited to a maximum of three trials","volume":"75","author":"Aboulghar","year":"2001","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.ejogrb.2017.01.016_bib0025","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0015-0282(99)00300-3","article-title":"Influence of age, diagnosis, and cycle number on pregnancy rates with gonadotropin-induced controlled ovarian hyperstimulation and intrauterine insemination","volume":"72","author":"Sahakyan","year":"1999","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0030","series-title":"Assessment and treatment for people with fertility problems","author":"NICE","year":"2013"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0035","doi-asserted-by":"crossref","first-page":"a716","DOI":"10.1136\/bmj.a716","article-title":"Clomifene citrate or unstimulated intrauterine insemination compared with expectant management for unexplained infertility: pragmatic randomised controlled trial","volume":"337","author":"Bhattacharya","year":"2008","journal-title":"BMJ"},{"issue":"July (9531)","key":"10.1016\/j.ejogrb.2017.01.016_bib0040","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0140-6736(06)69042-9","article-title":"Intrauterine insemination with controlled ovarian hyperstimulation versus expectant management for couples with unexplained subfertility and an intermediate prognosis: a randomised clinical trial","volume":"368","author":"Steures","year":"2006","journal-title":"Lancet"},{"issue":"May","key":"10.1016\/j.ejogrb.2017.01.016_bib0045","first-page":"1","article-title":"Replacing IUI with IVF for initial treatment of unexplained infertility: why this NICE recommendation is cause for concern","author":"Woodward","year":"2017","journal-title":"Hum Fertil (Camb, Engl)"},{"issue":"August","key":"10.1016\/j.ejogrb.2017.01.016_bib0050","first-page":"1","article-title":"An online survey of specialists\u2019 opinion on first line management options for unexplained subfertility","author":"Nandi","year":"2014","journal-title":"Hum Fertil (Camb, Engl)"},{"issue":"May (5)","key":"10.1016\/j.ejogrb.2017.01.016_bib0055","article-title":"Intrauterine insemination: a UK survey on the adherence to NICE clinical guidelines by fertility clinics","volume":"5","author":"Kim","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0060","doi-asserted-by":"crossref","first-page":"g252","DOI":"10.1136\/bmj.g252","article-title":"Are we overusing IVF?","volume":"348","author":"Kamphuis","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0065","series-title":"WHO laboratory manual for the examination and processing of human semen","author":"World Health Organization DoRHaR","year":"2010"},{"issue":"November (5)","key":"10.1016\/j.ejogrb.2017.01.016_bib0070","article-title":"When is clomiphene or gonadotropin intrauterine insemination futile? Results of the fast track and standard treatment trial and the forty and over yreatment yrial, two prospective randomized controlled trials","volume":"102","author":"Kaser","year":"2014","journal-title":"Fertil Steril"},{"issue":"August (8)","key":"10.1016\/j.ejogrb.2017.01.016_bib0075","first-page":"808","article-title":"Success rate of inseminations dependent on maternal age? An analysis of 4246 insemination cycles","volume":"73","author":"Schorsch","year":"2013","journal-title":"Geburtshilfe Frauenheilkunde"},{"issue":"April (4)","key":"10.1016\/j.ejogrb.2017.01.016_bib0080","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.fertnstert.2014.01.009","article-title":"Prognosis factors of pregnancy after intrauterine insemination with the husband\u2019s sperm: conclusions of an analysis of 2,019 cycles","volume":"101","author":"Dinelli","year":"2014","journal-title":"Fertil Steril"},{"issue":"August (2)","key":"10.1016\/j.ejogrb.2017.01.016_bib0085","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S1472-6483(10)60195-2","article-title":"Factors affecting live birth rate in intrauterine insemination cycles with recombinant gonadotrophin stimulation","volume":"17","author":"Erdem","year":"2008","journal-title":"Reprod Biomed Online"},{"issue":"March (3)","key":"10.1016\/j.ejogrb.2017.01.016_bib0090","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1093\/humrep\/14.3.698","article-title":"Intrauterine insemination treatment in subfertility: an analysis of factors affecting outcome","volume":"14","author":"Nuojua-Huttunen","year":"1999","journal-title":"Hum Reprod"},{"issue":"July (5)","key":"10.1016\/j.ejogrb.2017.01.016_bib0095","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3109\/01443615.2011.569780","article-title":"Factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics","volume":"31","author":"Demir","year":"2011","journal-title":"J Obstet Gynaecol"},{"issue":"July (2)","key":"10.1016\/j.ejogrb.2017.01.016_bib0100","first-page":"100","article-title":"The role of infertility etiology in success rate of intrauterine insemination cycles: an evaluation of predictive factors for pregnancy rate","volume":"7","author":"Ashrafi","year":"2013","journal-title":"Int J Fertil Steril"},{"issue":"May","key":"10.1016\/j.ejogrb.2017.01.016_bib0105","first-page":"173","article-title":"A four-cycle program improves the estimate of the cumulative pregnancy rate and increases the number of actual pregnancies in IUI treatment: a cohort study","volume":"176","author":"Allegra","year":"2017","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"4","key":"10.1016\/j.ejogrb.2017.01.016_bib0110","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.fertnstert.2013.06.004","article-title":"The national epidemic of multiple pregnancy and the contribution of assisted reproductive technology","volume":"100","author":"Ory","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0115","unstructured":"P B. One Child at a Time; Report of the Expert Group on Multiple Births After IVF, 2006."},{"issue":"March (1)","key":"10.1016\/j.ejogrb.2017.01.016_bib0120","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.tjog.2010.01.001","article-title":"Comparison of the effect of two different doses of recombinant gonadotropin for ovarian stimulation on the outcome of intrauterine insemination","volume":"50","author":"Chung","year":"2011","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"May (5)","key":"10.1016\/j.ejogrb.2017.01.016_bib0125","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/humrep\/dev062","article-title":"Low-dose human menopausal gonadotrophin versus clomiphene citrate in subfertile couples treated with intrauterine insemination: a randomized controlled trial","volume":"30","author":"Peeraer","year":"2015","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.01.016_bib0130","doi-asserted-by":"crossref","first-page":"g7771","DOI":"10.1136\/bmj.g7771","volume":"350","author":"Bensdorp","year":"2015","journal-title":"BMJ"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211517300167?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211517300167?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T15:02:46Z","timestamp":1779807766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211517300167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":26,"alternative-id":["S0301211517300167"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2017.01.016","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intrauterine insemination\u2014No more Mr. N.I.C.E. guy?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2017.01.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}