{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:47:58Z","timestamp":1791488878115,"version":"4.3.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.ejogrb.2017.09.006","type":"journal-article","created":{"date-parts":[[2017,9,8]],"date-time":"2017-09-08T21:01:40Z","timestamp":1504904500000},"page":"39-48","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Efficacy of Dehydroepiandrosterone (DHEA) to overcome the effect of ovarian ageing (DITTO): A proof of principle double blinded randomized placebo controlled trial"],"prefix":"10.1016","volume":"218","author":[{"given":"Amarin","family":"Narkwichean","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Maalouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Baumgarten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Polanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Raine-Fenning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kannamannadiar","family":"Jayaprakasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ejogrb.2017.09.006_bib0005","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1210\/er.2009-0006","article-title":"Ovarian aging: mechanisms and clinical consequences","volume":"30","author":"Broekmans","year":"2009","journal-title":"Endocr Rev"},{"issue":"6","key":"10.1016\/j.ejogrb.2017.09.006_bib0010","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/humupd\/dml034","article-title":"A systematic review of tests predicting ovarian reserve and IVF outcome","volume":"12","author":"Broekmans","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0015","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1097\/01.GME.0000123643.76105.27","article-title":"Antral follicle counts are related to age at natural fertility loss and age at menopause","volume":"11","author":"Broekmans","year":"2004","journal-title":"Menopause"},{"issue":"11","key":"10.1016\/j.ejogrb.2017.09.006_bib0020","doi-asserted-by":"crossref","first-page":"5502","DOI":"10.1210\/jc.2002-021839","article-title":"Impaired folliculogenesis and ovulation in older reproductive aged women","volume":"88","author":"Santoro","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.ejogrb.2017.09.006_bib0025","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0015-0282(01)02909-0","article-title":"Executive summary: stages of reproductive aging workshop (STRAW)","volume":"76","author":"Soules","year":"2001","journal-title":"Fertil Steril"},{"issue":"9039","key":"10.1016\/j.ejogrb.2017.09.006_bib0030","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/S0140-6736(96)05291-9","article-title":"Factors that affect outcome of in-vitro fertilisation treatment","volume":"348","author":"Templeton","year":"1996","journal-title":"Lancet"},{"issue":"4771","key":"10.1016\/j.ejogrb.2017.09.006_bib0035","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1126\/science.3755843","article-title":"Age and infertility","volume":"233","author":"Menken","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0040","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1477-7827-9-23","article-title":"Defining ovarian reserve to better understand ovarian aging","volume":"9","author":"Gleicher","year":"2011","journal-title":"Reprod Biol Endocrinol"},{"issue":"2","key":"10.1016\/j.ejogrb.2017.09.006_bib0045","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0015-0282(00)00625-7","article-title":"Do women with unexplained recurrent pregnancy loss have higher day 3 serum FSH and estradiol values?","volume":"74","author":"Trout","year":"2000","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.ejogrb.2017.09.006_bib0050","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1086\/302907","article-title":"Women with a reduced ovarian complement may have an increased risk for a child with down syndrome","volume":"66","author":"Freeman","year":"2000","journal-title":"Am J Hum Genet"},{"issue":"3-4","key":"10.1016\/j.ejogrb.2017.09.006_bib0055","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1159\/000086899","article-title":"Biological aging and the etiology of aneuploidy","volume":"111","author":"Warburton","year":"2005","journal-title":"Cytogenet Genome Res"},{"issue":"5","key":"10.1016\/j.ejogrb.2017.09.006_bib0060","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/humrep\/17.5.1171","article-title":"Experimental evidence that changes in oocyte growth influence meiotic chromosome segregation","volume":"17","author":"Hodges","year":"2002","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2017.09.006_bib0065","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1093\/humrep\/dem408","article-title":"A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause","volume":"23","author":"Hansen","year":"2008","journal-title":"Hum Reprod"},{"issue":"9","key":"10.1016\/j.ejogrb.2017.09.006_bib0070","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1093\/humrep\/16.9.2014","article-title":"The role of genetic factors in age at natural menopause","volume":"16","author":"de Bruin","year":"2001","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2017.09.006_bib0075","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S1472-6483(10)60341-0","article-title":"Natural history of the mammalian oocyte","volume":"15","author":"Telfer","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0080","first-page":"429","article-title":"Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans","volume":"61","author":"Campbell","year":"2003","journal-title":"Reprod Suppl"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0085","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1749-6632.1995.tb17370.x","article-title":"Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline","volume":"774","author":"Hornsby","year":"1995","journal-title":"Ann N Y Acad Sci"},{"issue":"10","key":"10.1016\/j.ejogrb.2017.09.006_bib0090","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/humrep\/15.10.2129","article-title":"Dehydroepiandrosterone supplementation augments ovarian stimulation in poor responders: a case series","volume":"15","author":"Casson","year":"2000","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2017.09.006_bib0095","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.rbmo.2010.04.006","article-title":"Improvement in diminished ovarian reserve after dehydroepiandrosterone supplementation","volume":"21","author":"Gleicher","year":"2010","journal-title":"Reprod Biomed Online"},{"issue":"11","key":"10.1016\/j.ejogrb.2017.09.006_bib0100","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/humrep\/del254","article-title":"Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF","volume":"21","author":"Barad","year":"2006","journal-title":"Hum Reprod"},{"issue":"12","key":"10.1016\/j.ejogrb.2017.09.006_bib0105","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s10815-007-9178-x","article-title":"Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function","volume":"24","author":"Barad","year":"2007","journal-title":"J Assist Reprod Genet"},{"issue":"3","key":"10.1016\/j.ejogrb.2017.09.006_bib0110","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.fertnstert.2005.02.049","article-title":"Increased oocyte production after treatment with dehydroepiandrosterone","volume":"84","author":"Barad","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0115","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.rbmo.2009.06.006","article-title":"Dehydroepiandrosterone supplementation improves ovarian response and cycle outcome in poor responders","volume":"19","author":"Sonmezer","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0120","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1093\/humrep\/deq220","article-title":"Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: a randomized prospective study","volume":"25","author":"Wiser","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0125","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/humrep\/det408","article-title":"Effects of dehydroepiandrosterone on in vivo ovine follicular development","volume":"29","author":"Narkwichean","year":"2014","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0130","first-page":"429","article-title":"Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans","volume":"61","author":"Campbell","year":"2003","journal-title":"Reprod Suppl"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0135","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.1172\/JCI2081","article-title":"Androgens stimulate early stages of follicular growth in the primate ovary","volume":"101","author":"Vendola","year":"1998","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0140","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1210\/jcem.83.7.4917","article-title":"Androgen receptor gene expression in the primate ovary: cellular localization, regulation, and functional correlations","volume":"83","author":"Weil","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0145","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1095\/biolreprod.107.064089","article-title":"Androgen actions and the ovary","volume":"78","author":"Walters","year":"2008","journal-title":"Biol Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0150","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1477-7827-11-44","article-title":"Efficacy of dehydroepiandrosterone to improve ovarian response in women with diminished ovarian reserve: a meta-analysis","volume":"11","author":"Narkwichean","year":"2013","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0155","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.fertnstert.2014.03.044","article-title":"A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders","volume":"102","author":"Yeung","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0160","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ejogrb.2013.11.008","article-title":"Does dehydroepiandrosterone supplementation really affect IVF-ICSI outcome in women with poor ovarian reserve?","volume":"173","author":"Kara","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0165","doi-asserted-by":"crossref","first-page":"e99858","DOI":"10.1371\/journal.pone.0099858","article-title":"Effect of dehydroepiandrosterone administration in patients with poor ovarian response according to the Bologna criteria","volume":"9","author":"Xu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0170","doi-asserted-by":"crossref","first-page":"175","DOI":"10.4103\/0974-1208.142477","article-title":"Impact of dehydroepiandrosterone on clinical outcome in poor responders: a pilot study in women undergoing in vitro fertilization, using bologna criteria","volume":"7","author":"Jirge","year":"2014","journal-title":"J Hum Reprod Sci"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0175","series-title":"Poor responders: how to define, diagnose and treat?","author":"Leong","year":"2010"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0180","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.fertnstert.2012.05.042","article-title":"Prediction of in vitro fertilization outcome at different antral follicle count thresholds in a prospective cohort of 1,012 women","volume":"98","author":"Jayaprakasan","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0185","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/humrep\/den480","article-title":"Anti-Mullerian hormone-based approach to controlled ovarian stimulation for assisted conception","volume":"24","author":"Nelson","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0190","doi-asserted-by":"crossref","first-page":"e005767","DOI":"10.1136\/bmjopen-2014-005767","article-title":"Efficacy of dehydroepiandrosterone to overcome the effect of ovarian ageing (DITTO): a proof of principle randomised controlled trial protocol","volume":"4","author":"Jayaprakasan","year":"2014","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0195","series-title":"Mediagnost. IGF-1 ELISA Reutlingen, Germany: Mediagnost 2014 [updated 1st August 2014]","year":"2014"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0200","series-title":"Demeditec. DHEA ELISA Kiel-Wellsee, Germany: Demeditec Diagnostics; 2014","year":"2014"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0205","series-title":"AMH Gen II ELISA [Instruction Manual]. High Wycombe: Beckman Coulter (UK) Ltd; 2014","author":"Beckman","year":"2014"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0210","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0215","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.fertnstert.2014.03.044","article-title":"A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders","volume":"102","author":"Yeung","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0220","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.fertnstert.2008.10.042","article-title":"A prospective, comparative analysis of anti-mullerian hormone, inhibin-B, and three-dimensional ultrasound determinants of ovarian reserve in the prediction of poor response to controlled ovarian stimulation","volume":"93","author":"Jayaprakasan","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0225","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1093\/humrep\/der092","article-title":"ESHRE consensus on the definition of \u2018poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria","volume":"26","author":"Ferraretti","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0230","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/humupd\/dml038","article-title":"Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis","volume":"12","author":"Kolibianakis","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0235","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001750.pub3","article-title":"Gonadotrophin-releasing hormone antagonists for assisted reproductive technology","author":"Al-Inany","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0240","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1742-4755-4-12","volume":"4","author":"Sunkara","year":"2007","journal-title":"Reprod Health"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0245","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.fertnstert.2013.09.035","article-title":"Long gonadotropin-releasing hormone agonist versus short agonist versus antagonist regimens in poor responders undergoing in vitro fertilization: a randomized controlled trial","volume":"101","author":"Sunkara","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0250","series-title":"Human Fertilisation and Embryology Authority Live births per treatment cycle started in the year ending 2nd quarter 2013. 2014 [cited 2015 1 July 2015]; Nurture Fertility, East Midlands, success rates]","year":"2014"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0255","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10815-010-9491-7","article-title":"Biomarkers of human oocyte developmental competence expressed in cumulus cells before ICSI: a preliminary study","volume":"28","author":"Assidi","year":"2011","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0260","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1530\/REP-07-0182","article-title":"Association between human oocyte developmental competence and expression levels of some cumulus genes","volume":"134","author":"Cillo","year":"2007","journal-title":"Reproduction"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0265","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1093\/humrep\/dem336","article-title":"Gene expression in human cumulus cells: one approach to oocyte competence","volume":"22","author":"Feuerstein","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0270","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1093\/humrep\/deh535","article-title":"Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF","volume":"19","author":"McKenzie","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0275","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1477-7827-9-67","article-title":"Dehydroepiandrosterone (DHEA) supplementation in diminished ovarian reserve (DOR)","volume":"9","author":"Gleicher","year":"2011","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0280","doi-asserted-by":"crossref","first-page":"4533","DOI":"10.1210\/en.2012-1158","article-title":"The role of anti-M\u00fcllerian hormone (AMH) during follicle development in a monovulatory species (sheep)","volume":"153","author":"Campbell","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.ejogrb.2017.09.006_bib0285","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1365-2265.2012.04451.x","article-title":"What does anti-Mullerian hormone tell you about ovarian function?","volume":"77","author":"Anderson","year":"2012","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211517304281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211517304281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:39:15Z","timestamp":1759556355000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211517304281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":57,"alternative-id":["S0301211517304281"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2017.09.006","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of Dehydroepiandrosterone (DHEA) to overcome the effect of ovarian ageing (DITTO): A proof of principle double blinded randomized placebo controlled trial","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2017.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2017 Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}