{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T13:24:55Z","timestamp":1770729895337,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.ejogrb.2018.05.004","type":"journal-article","created":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T13:22:27Z","timestamp":1525785747000},"page":"236-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Magnesium sulfate versus esomeprazole impact on the neonates of preeclamptic rats"],"prefix":"10.1016","volume":"225","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6557-4396","authenticated-orcid":false,"given":"Amani N.","family":"Shafik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud A.","family":"Khattab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed H.","family":"Osman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2018.05.004_bib0005","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1155\/2011\/214365","article-title":"Maternal preeclampsia and neonatal outcomes","volume":"2011","author":"Backes","year":"2011","journal-title":"J Pregnancy"},{"issue":"09","key":"10.1016\/j.ejogrb.2018.05.004_bib0010","first-page":"8","article-title":"Serum magnesium levels in healthy pregnant and pre-eclamptic patients. A cross-Section study","volume":"04","author":"Adekanle","year":"2014","journal-title":"Open J Obstetr Gynecol"},{"issue":"8","key":"10.1016\/j.ejogrb.2018.05.004_bib0015","first-page":"QC08","article-title":"Single loading low dose MgSo(4) regimen: a simple, safe and effective alternative to pritchard\u2019s regimen for indian women","volume":"11","author":"Nagaria","year":"2017","journal-title":"J Clin Diagn Res: JCDR"},{"issue":"1","key":"10.1016\/j.ejogrb.2018.05.004_bib0020","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1097\/AOG.0000000000001267","article-title":"Committee opinion No 652: magnesium sulfate use in obstetrics","volume":"127","author":"The American College of Obstetricians and Gynecologists","year":"2016","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0025","article-title":"Circulating angiogenic factors and the risk of preeclampsia in systemic lupus erythematosus pregnancies","author":"Lea\u00f1os-Miranda","year":"2018","journal-title":"J Rheumatol"},{"issue":"3","key":"10.1016\/j.ejogrb.2018.05.004_bib0030","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1161\/HYPERTENSIONAHA.116.08408","article-title":"Proton pump inhibitors decrease soluble fms-like tyrosine kinase-1 and soluble endoglin secretion, decrease hypertension, and rescue endothelial dysfunction","volume":"69","author":"Onda","year":"2017","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.ejogrb.2018.05.004_bib0035","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.apjr.2016.04.004","article-title":"An overview of the current methodologies used for evaluation of anti-fertility agents","volume":"5","author":"Shah","year":"2016","journal-title":"Asian Pac J Reprod"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0040","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1590\/S1516-31801999000500004","article-title":"The effect of chronic nitric oxide inhibition on vascular reactivity and blood pressure in pregnant rats","volume":"117","author":"Takiuti","year":"1999","journal-title":"Sao Paulo Med J"},{"issue":"5","key":"10.1016\/j.ejogrb.2018.05.004_bib0045","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.lfs.2012.06.036","article-title":"Hepatoprotective and anti-inflammatory effects of silibinin on experimental preeclampsia induced by l-NAME in rats","volume":"91","author":"de Souza","year":"2012","journal-title":"Life Sci"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0050","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1038\/hr.2012.103","article-title":"Magnesium sulfate therapy of preeclampsia: an old tool with new mechanism of action and prospect in management and prophylaxis","volume":"35","author":"Korish","year":"2012","journal-title":"Hypertens Res"},{"issue":"4","key":"10.1016\/j.ejogrb.2018.05.004_bib0055","doi-asserted-by":"crossref","first-page":"424","DOI":"10.4103\/0975-1483.71624","article-title":"A study on drug-Drug interaction of esomeprazole and anti-diabetic drugs","volume":"2","author":"Swamy","year":"2010","journal-title":"J Young Pharm: JYP"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0060","series-title":"Bancroft's Theory and Practice of Histological Techniques","author":"Bancroft","year":"2013"},{"issue":"24.08","key":"10.1016\/j.ejogrb.2018.05.004_bib0065","article-title":"Biostatistics 102: quantitative data\u2013parametric & non-parametric tests. blood pressure","volume":"140","author":"Chan","year":"2003","journal-title":"Singapore Med J"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0070","first-page":"354","article-title":"Biostatistics 301. repeated measurement analysis","volume":"45","author":"Chan","year":"2004","journal-title":"Singapore Med J"},{"issue":"10","key":"10.1016\/j.ejogrb.2018.05.004_bib0075","first-page":"498","article-title":"Biostatistics 103: qualitative data-tests of independence","volume":"44","author":"Chan","year":"2003","journal-title":"Singapore Med J"},{"issue":"3","key":"10.1016\/j.ejogrb.2018.05.004_bib0080","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s00404-016-4281-9","article-title":"Elective delivery versus expectant management for pre-eclampsia: a meta-analysis of RCTs","volume":"295","author":"Wang","year":"2017","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"10.1016\/j.ejogrb.2018.05.004_bib0085","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ejmhg.2015.03.006","article-title":"The role of microRNAs on angiogenesis and vascular pressure in preeclampsia: the evidence from systematic review","volume":"16","author":"Harapan","year":"2015","journal-title":"Egypt J Med Hum Genet"},{"issue":"4","key":"10.1016\/j.ejogrb.2018.05.004_bib0090","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s11906-011-0204-0","article-title":"Mechanisms and potential therapies for preeclampsia","volume":"13","author":"George","year":"2011","journal-title":"Curr Hypertens Rep"},{"issue":"8","key":"10.1016\/j.ejogrb.2018.05.004_bib0095","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1093\/humrep\/15.8.1838","article-title":"Inhibition of nitric oxide synthesis causes preterm delivery in the mouse","volume":"15","author":"Tiboni","year":"2000","journal-title":"Hum Reprod"},{"issue":"11","key":"10.1016\/j.ejogrb.2018.05.004_bib0100","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11906-016-0688-8","article-title":"Effects of aspirin on endothelial function and hypertension","volume":"18","author":"Dzeshka","year":"2016","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0105","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1155\/2013\/953150","article-title":"Preeclampsia is a biomarker for vascular disease in both mother and child: the need for a medical alert system","volume":"2013","author":"Hakim","year":"2013","journal-title":"Int J Pediatr"},{"issue":"4","key":"10.1016\/j.ejogrb.2018.05.004_bib0110","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1161\/STROKEAHA.108.527788","article-title":"Magnesium sulfate treatment for the prevention of eclampsia: a brief review","volume":"40","author":"Euser","year":"2009","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.ejogrb.2018.05.004_bib0115","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1139\/y87-120","article-title":"Mg2+-Ca2+ interaction in contractility of vascular smooth muscle: mg2+ versus organic calcium channel blockers on myogenic tone and agonist-induced responsiveness of blood vessels","volume":"65","author":"Altura","year":"1987","journal-title":"Can J Physiol Pharmacol"},{"issue":"10","key":"10.1016\/j.ejogrb.2018.05.004_bib0120","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1055\/s-0032-1316440","article-title":"Neonatal effects of magnesium sulfate given to the mother","volume":"29","author":"Abbassi-Ghanavati","year":"2012","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.ejogrb.2018.05.004_bib0125","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1056\/NEJMoa0801187","article-title":"A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy","volume":"359","author":"Rouse","year":"2008","journal-title":"N Engl J Med"},{"issue":"24","key":"10.1016\/j.ejogrb.2018.05.004_bib0130","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.109.853127","article-title":"Preeclampsia, a disease of the maternal endothelium: the role of anti-angiogenic factors and implications for later cardiovascular disease","volume":"123","author":"Powe","year":"2011","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.ejogrb.2018.05.004_bib0135","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3109\/10641950902968684","article-title":"Soluble endoglin for the prediction of preeclampsia in a high risk cohort","volume":"29","author":"Maynard","year":"2010","journal-title":"Hypertens Pregnancy"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211518302185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211518302185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T16:51:33Z","timestamp":1770655893000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211518302185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":27,"alternative-id":["S0301211518302185"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2018.05.004","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Magnesium sulfate versus esomeprazole impact on the neonates of preeclamptic rats","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2018.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}