{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:54:05Z","timestamp":1774648445400,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.ejogrb.2019.10.023","type":"journal-article","created":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T11:36:51Z","timestamp":1571744211000},"page":"111-119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Efficacy and safety of oral vs vaginal misoprostol for cervical priming before hysteroscopy: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"243","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9579-8366","authenticated-orcid":false,"given":"Ahmed M.","family":"Abdelhakim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al-Hussein","family":"Gadallah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed M.","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2019.10.023_bib0005","article-title":"Preoperative ripening of the cervix before operative hysteroscopy","volume":"4","author":"Al-Fozan","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0010","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1001\/jama.1984.03340400036021","article-title":"Prevention of uterine perforation during curettage abortion","volume":"251","author":"Grimes","year":"1984","journal-title":"JAMA"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0015","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1016\/S0140-6736(83)92464-9","article-title":"Measures to prevent cervical injury during suction curettage abortion","volume":"1","author":"Schulz","year":"1983","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0020","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1093\/humrep\/deh397","article-title":"Cervical priming prior to operative hysteroscopy: a randomized comparison of laminaria versus misoprostol","volume":"19","author":"Darwish","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0025","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.fertnstert.2007.03.099","article-title":"Cervical ripening before operative hysteroscopy in premenopausal women: a randomized, double-blind, placebo-controlled comparison of vaginal and oral misoprostol","volume":"89","author":"Batukan","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0030","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.fertnstert.2014.04.040","article-title":"Effectiveness of different routes of misoprostol administration before operative hysteroscopy: a randomized, controlled trial","volume":"102","author":"Song","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0035","series-title":"Cochrane handbook for systematic reviews of interventions","author":"Higgins","year":"2011"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0045","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0050","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.jmig.2016.08.002","article-title":"Cervical priming by vaginal or oral misoprostol before operative hysteroscopy: a double-blind, randomized controlled trial","volume":"23","author":"Nada","year":"2016","journal-title":"J Minimal Invasive Gynecol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0055","series-title":"Assessing risk of bias in included studies. in: cochrane handbook for systematic reviews of interventions","first-page":"3","author":"Green","year":"2011"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0060","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0065","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1002\/sim.1461","article-title":"Adjusting for publication bias in the presence of heterogeneity","volume":"22","author":"Terrin","year":"2003","journal-title":"Stat Med"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0075","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jmig.2016.12.024","article-title":"Different routes of misoprostol for same-day cervical priming prior to operative hysteroscopy: a randomized blinded trial","volume":"24","author":"Ganer Herman","year":"2017","journal-title":"J Minimal Invasive Gynecol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0080","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1093\/humrep\/del098","article-title":"Misoprostol for cervical ripening in non-pregnant women: a randomized double-blind controlled trial of oral versus vaginal regimens","volume":"21","author":"Choksuchat","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0085","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1093\/humrep\/deq083","article-title":"The use of misoprostol before hysteroscopic surgery in non-pregnant premenopausal women: a randomized comparison of sublingual, oral and vaginal administrations","volume":"25","author":"Lee","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0090","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.ijgo.2011.10.015","article-title":"Misoprostol for cervical ripening before diagnostic hysteroscopy in nulliparous women","volume":"116","author":"Bakas","year":"2012","journal-title":"Int J Gynecol Obstet"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0095","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.fertnstert.2010.07.1066","article-title":"Effectiveness of misoprostol for office hysteroscopy without anesthesia in infertile patients","volume":"95","author":"Sordia-Hern\u00e1ndez","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0100","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/humupd\/dms014","article-title":"Misoprostol prior to hysteroscopy in premenopausal and post-menopausal women. A systematic review and meta-analysis","volume":"18","author":"Polyzos","year":"2012","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0105","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00404-018-4764-y","article-title":"Effect of cervical priming with misoprostol on cervical entry in women undergoing vaginoscopic hysteroscopy for evaluation of abnormal uterine bleeding: a randomized controlled trial","volume":"298","author":"Nandhini","year":"2018","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0165-0378(02)00007-4","article-title":"Inflammatory mediators and cervical ripening","volume":"57","author":"Kelly","year":"2002","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0115","unstructured":"W. Rath, R. Osmers, H.W. Stuhlsatz, B.C. Adelmann-Grill. Biochemical principles of cervix ripening and dilatation. Zeitschrift Fur Geburtshilfe Und Perinatologie n.d. 198 pp. 186\u2013195."},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0120","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jmig.2016.12.024","article-title":"Different routes of misoprostol for same-day cervical priming prior to operative hysteroscopy: a randomized blinded trial","volume":"24","author":"Ganer Herman","year":"2017","journal-title":"J Minimal Invasive Gynecol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0125","doi-asserted-by":"crossref","DOI":"10.1080\/13645706.2018.1559195","article-title":"Effectiveness of misoprostol administration for cervical ripening in women before operative hysteroscopy: a randomized, double-blinded controlled trial","author":"Zhuo","year":"2019","journal-title":"Minim Invasive Ther Allied Technol"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0130","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/humrep\/17.2.332","article-title":"Pharmacokinetics of different routes of administration of misoprostol","volume":"17","author":"Tang","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2019.10.023_bib0135","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1097\/01.AOG.0000124783.38974.53","article-title":"Oral, rectal, and vaginal pharmacokinetics of misoprostol","volume":"103","author":"Khan","year":"2004","journal-title":"Obstet Gynecol"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211519304798?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211519304798?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:46:51Z","timestamp":1759556811000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211519304798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":27,"alternative-id":["S0301211519304798"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2019.10.023","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of oral vs vaginal misoprostol for cervical priming before hysteroscopy: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2019.10.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}