{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:39:37Z","timestamp":1780447177224,"version":"3.54.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Guangzhou Institute of Pediatrics"},{"name":"Guangzhou Women and Children\u2019s Medical Center","award":["IP-2019-004"],"award-info":[{"award-number":["IP-2019-004"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.ejogrb.2020.07.036","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T20:55:19Z","timestamp":1595364919000},"page":"431-433","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Use of noninvasive prenatal screening with cell-free DNA in late pregnancy with sonographic soft markers"],"prefix":"10.1016","volume":"252","author":[{"given":"Jun-Hui","family":"Wan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Zhi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"December","key":"10.1016\/j.ejogrb.2020.07.036_bib0005","first-page":"1","article-title":"First-trimester screening-biomarkers and cell-free DNA","volume":"8","author":"Suciu","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0010","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/pd.5590","article-title":"Is there still a role for nuchal translucency measurement in the changing paradigm of first trimester screening?","volume":"40","author":"Bardi","year":"2020","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0015","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ejogrb.2015.10.001","article-title":"Uptake of non-invasive prenatal testing in Chinese women: money matters","volume":"195","author":"Han","year":"2015","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0020","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/uog.12575","article-title":"Additional value of prenatal genomic array testing in fetuses with isolated structural ultrasound abnormalities and a normal karyotype: a systematic review of the literature","volume":"43","author":"de Wit","year":"2014","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0025","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1002\/pd.5545","article-title":"Prenatal chromosomal microarray testing of fetuses with ultrasound structural anomalies: a prospective cohort study of over 1000 consecutive cases","volume":"39","author":"Chong","year":"2019","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0030","doi-asserted-by":"crossref","first-page":"338","DOI":"10.3109\/14767058.2016.1172566","article-title":"Fetal aneuploidy screening with cell-free DNA in late gestation","volume":"30","author":"Taneja","year":"2017","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0035","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/uog.6220","article-title":"Second-trimester genetic sonogram for detection of fetal chromosomal abnormalities in a community-based antenatal testing unit","volume":"33","author":"Bottalico","year":"2009","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0040","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/uog.12364","article-title":"Meta-analysis of second-trimester markers for trisomy 21","volume":"41","author":"Agathokleous","year":"2013","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0045","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1002\/pd.4115","article-title":"The significance of the second trimester sonographic soft markers in pregnancies after normal first trimester screening","volume":"33","author":"Kaijomaa","year":"2013","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0050","doi-asserted-by":"crossref","first-page":"321","DOI":"10.7863\/jum.2009.28.3.321","article-title":"Second-trimester genetic sonography after first-trimester combined screening for trisomy 21","volume":"28","author":"Wax","year":"2009","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0055","doi-asserted-by":"crossref","first-page":"906","DOI":"10.2214\/AJR.17.18343","article-title":"How to integrate cell-free DNA screening with sonographic markers for aneuploidy: an update","volume":"210","author":"Winter","year":"2018","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0060","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/pd.373","article-title":"Psychological impact of the detection of soft markers on routine ultrasound scanning: a pilot study investigating the modifying role of information","volume":"22","author":"Watson","year":"2002","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0065","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2017.01.005","article-title":"The role of ultrasound in women who undergo cell-free DNA screening","volume":"216","author":"Society for Maternal-Fetal Medicine (SMFM)","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0070","first-page":"234","article-title":"Risk of chromosomal abnormalities in patients with idiopathic polyhydramnios","volume":"79","author":"Brady","year":"1992","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0075","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ejmg.2015.06.010","article-title":"Chromosomal aberrations in idiopathic polyhydramnios: a systematic review and meta-analysis","volume":"58","author":"Sagi-Dain","year":"2015","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0080","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/uog.17228","article-title":"Clinical utility of non-invasive prenatal testing in pregnancies with ultrasound anomalies","volume":"49","author":"Beulen","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0085","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.3109\/14767058.2012.718396","article-title":"Third-trimester genetic amniocentesis in mainland China","volume":"25","author":"Liao","year":"2012","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ejogrb.2020.07.036_bib0090","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/gim.2016.97","article-title":"Noninvasive prenatal screening for fetal aneuploidy, 2016 update: a position statement of the American College of Medical Genetics and Genomics","volume":"18","author":"Gregg","year":"2016","journal-title":"Genet Med"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211520304784?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211520304784?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:52:17Z","timestamp":1759557137000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211520304784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":18,"alternative-id":["S0301211520304784"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2020.07.036","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of noninvasive prenatal screening with cell-free DNA in late pregnancy with sonographic soft markers","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2020.07.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}