{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T02:23:44Z","timestamp":1793327024767,"version":"4.5.0"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.ejogrb.2021.10.027","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T12:13:07Z","timestamp":1635941587000},"page":"161-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"special_numbering":"C","title":["Effect of curcumin on sperm parameters after the cryopreservation"],"prefix":"10.1016","volume":"267","author":[{"given":"Fatma","family":"Nur Karakus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibel","family":"Bulgurcuoglu Kuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyhun","family":"Solakoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2021.10.027_b0005","doi-asserted-by":"crossref","unstructured":"Royere D, Barthelemy C, Hamamah S, Lansac J. Cryopreservation of spermatozoa: a 1996 review. C. 2, Human Reproduction Update; 1996.","DOI":"10.1093\/humupd\/2.6.553"},{"issue":"105","key":"10.1016\/j.ejogrb.2021.10.027_b0010","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cryobiol.2017.12.009","article-title":"Mitochondria-targeted antioxidant MitoTEMPO improves the post-thaw sperm quality","volume":"80","author":"Lu","year":"2018","journal-title":"Cryobiology"},{"issue":"9","key":"10.1016\/j.ejogrb.2021.10.027_b0015","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1093\/humrep\/dep214","article-title":"Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis","volume":"24","author":"Thomson","year":"2009","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0020","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1472-6483(10)60254-4","article-title":"Effect of antioxidant supplementation of cryopreservation medium on post-thaw integrity of human spermatozoa","volume":"18","author":"Taylor","year":"2009","journal-title":"Reprod Biomed Online"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0025","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s10561-016-9566-5","article-title":"The role of antioxidants in sperm freezing: a review","volume":"17","author":"Amidi","year":"2016","journal-title":"Cell Tissue Bank"},{"issue":"1-4","key":"10.1016\/j.ejogrb.2021.10.027_b0030","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/biof.5520130125","article-title":"Recent studies on the biofunctions and biotransformations of curcumin","volume":"13","author":"Lin","year":"2000","journal-title":"BioFactors"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0035","doi-asserted-by":"crossref","unstructured":"de Lamirande E, O\u2019Flaherty C. Sperm activation: Role of reactive oxygen species and kinases. C. 1784, Biochimica et Biophysica Acta - Proteins and Proteomics. Elsevier; 2008. s. 106\u201315.","DOI":"10.1016\/j.bbapap.2007.08.024"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0040","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/humrep\/13.4.896","article-title":"Reactive oxygen species: Potential cause for DNA fragmentation in human spermatozoa","volume":"13","author":"Lopes","year":"1998","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0045","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/mrd.20285","article-title":"A comparative study of oxidative DNA damage in mammalian spermatozoa","volume":"71","author":"Bennetts","year":"2005","journal-title":"Mol Reprod Dev"},{"issue":"5","key":"10.1016\/j.ejogrb.2021.10.027_b0050","first-page":"958","article-title":"Detection of damage in mammalian sperm cells. I\u00e7inde: Theriogenology","volume":"65","author":"Silva","year":"2006","journal-title":"Elsevier"},{"issue":"6","key":"10.1016\/j.ejogrb.2021.10.027_b0055","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0015-0282(97)81448-3","article-title":"Seminal reactive oxygen species and sperm motility and morphology in men with spinal cord injury","volume":"67","author":"Padron","year":"1997","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.smallrumres.2009.11.015","article-title":"The effect of antioxidants on post-thawed Angora goat (Capra hircus ancryrensis) sperm parameters, lipid peroxidation and antioxidant activities","volume":"89","author":"Bucak","year":"2010","journal-title":"Small Rumin Res."},{"key":"10.1016\/j.ejogrb.2021.10.027_b0065","doi-asserted-by":"crossref","unstructured":"Slobodan V. Jovanovic, Charles W. Boone, Steen Steenken, Manuela Trinoga, Kaskey RB. How Curcumin Works Preferentially with Water Soluble Antioxidants; 2001.","DOI":"10.1021\/ja003823x"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0070","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.foodchem.2005.06.037","article-title":"Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin","volume":"98","author":"Jayaprakasha","year":"2006","journal-title":"Food Chem"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0075","unstructured":"World Health Organization. WHO laboratory manual for the examination and processing of human semen Fifth edition. 2010;290."},{"key":"10.1016\/j.ejogrb.2021.10.027_b0080","series-title":"The Sperm Cell","first-page":"249","author":"Terquem","year":"1982"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0085","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2605.1999.00162.x","article-title":"Effect of freeze-thawing procedure on chromatin stability, morphological alteration and membrane integrity of human spermatozoa in fertile and subfertile men","volume":"162","author":"Hammadeh","year":"1999","journal-title":"Int J Androl"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0090","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0015-0282(16)47963-X","article-title":"A test for the practical evaluation of male fertility by acridine orange (AO) fluorescence","volume":"42","author":"Tejada","year":"1984","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0095","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/j.1939-4640.2001.tb02152.x","article-title":"Comparative study of cytochemical tests for sperm chromatin integrity","volume":"22","author":"Erenpreiss","year":"2001","journal-title":"J Androl"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0100","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/emm.2007.16","article-title":"Curcumin reduces cold storage-induced damage in human cardiac myoblasts","volume":"39","author":"Abuarqoub","year":"2007","journal-title":"Exp Mol Med"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0105","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ejogrb.2014.01.024","article-title":"Curcumin as a potential non-steroidal contraceptive with spermicidal and microbicidal properties","volume":"176","author":"Naz","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"3-4","key":"10.1016\/j.ejogrb.2021.10.027_b0110","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.lfs.2007.10.026","article-title":"Curcumin treatment enhances islet recovery by induction of heat shock response proteins, Hsp70 and heme oxygenase-1, during cryopreservation","volume":"82","author":"Kanitkar","year":"2008","journal-title":"Life Sci"},{"issue":"9","key":"10.1016\/j.ejogrb.2021.10.027_b0115","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/asj.12395","article-title":"The effect of Curcuma longa extracted (curcumin) on the quality of cryopreserved boar semen","volume":"86","author":"Chanapiwat","year":"2015","journal-title":"Anim Sci J."},{"key":"10.1016\/j.ejogrb.2021.10.027_b0120","first-page":"102","article-title":"Effects of curcumin and dithioerythritol on frozen-thawed bovine semen","volume":"44","author":"K\u00fc\u00e7\u00fckg\u00fcnay","year":"2011","journal-title":"Andrologia"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0125","first-page":"185","article-title":"Effect of curcumin on rat sperm morphology after the freeze-thawing process","volume":"4","author":"Soleimanzadeh","year":"2013","journal-title":"Artic Vet Res Forum"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0130","first-page":"1","article-title":"Freezability of water buffalo bull (Bubalus bubalis) spermatozoa is improved with the addition of curcumin (diferuoyl methane) in semen extender","volume":"7","author":"Soltani","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0135","series-title":"Turmeric and the healing curcuminoids","author":"Majeed","year":"1999"},{"issue":"10","key":"10.1016\/j.ejogrb.2021.10.027_b0140","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1007\/s43032-021-00572-9","article-title":"Protective Effects of Curcumin on the Outcome of Cryopreservation in Human Sperm","volume":"28","author":"Santonastaso","year":"2021","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0145","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.anireprosci.2016.06.008","article-title":"Curcumin has protective and antioxidant properties on bull spermatozoa subjected to induced oxidative stress","volume":"172","author":"Tvrd\u00e1","year":"2016","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0150","first-page":"31","article-title":"Effects of curcumin on reproductive parameters in male mice","volume":"1","author":"Salahshoor","year":"2012","journal-title":"J Clin Res Paramed Sci"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0155","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/mrd.21276","article-title":"Can curcumin provide an ideal contraceptive?","volume":"78","author":"Naz","year":"2011","journal-title":"Mol Reprod Dev"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0160","first-page":"62","article-title":"The effect of curcumin on intracellular pH (pHi), membrane hyperpolarization and sperm motility","volume":"15","author":"Naz","year":"2014","journal-title":"J Reprod Infertil"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0165","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1006\/excr.1998.4064","article-title":"Mitochondrial membrane potential and DNA stainability in human sperm cells: A flow cytometry analysis with implications for male infertility","volume":"241","author":"Troiano","year":"1998","journal-title":"Exp Cell Res"},{"issue":"18","key":"10.1016\/j.ejogrb.2021.10.027_b0170","doi-asserted-by":"crossref","first-page":"7305","DOI":"10.1073\/pnas.87.18.7305","article-title":"Protein kinase C is present in human sperm: Possible role in flagellar motility","volume":"87","author":"Rotem","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0175","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0010-7824(03)00163-X","article-title":"Curcumin: A potential vaginal contraceptive","volume":"68","author":"Rithaporn","year":"2003","journal-title":"Contraception"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0180","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1007\/s00128-010-9942-y","article-title":"Protective role of curcumin on lindane induced reproductive toxicity in male wistar rats","volume":"84","author":"Sharma","year":"2010","journal-title":"Bull Environ Contam Toxicol"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0185","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.etap.2007.04.009","article-title":"Effect of curcumin on chromium-induced oxidative damage in male reproductive system","volume":"24","author":"Chandra","year":"2007","journal-title":"Environ Toxicol Pharmacol"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0190","first-page":"1131","article-title":"Protective effects of curcumin in cyclophosphamide induced sperm head abnormalities in male mice","volume":"4","author":"Dev","year":"2013","journal-title":"Int J Pharm Biol Sci."},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0195","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.fertnstert.2007.07.1300","article-title":"Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa","volume":"90","author":"MATHURIA","year":"2008","journal-title":"Fertil Steril"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0200","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/0003-9861(92)90040-4","article-title":"Turmerin: A water soluble antioxidant peptide from turmeric [Curcuma longa]","volume":"292","author":"Srinivas","year":"1992","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0205","first-page":"229","article-title":"Use of tumeric and curcumin to alleviate adverse reproductive outcomes of water: Nitrate pollution in male rats","volume":"9","author":"Azza","year":"2011","journal-title":"Nat Sci"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0210","doi-asserted-by":"crossref","unstructured":"Zini A, Libman J. Sperm DNA damage: Clinical significance in the era of assisted reproduction. C. 175, CMAJ. 2006. s. 495\u2013500.","DOI":"10.1503\/cmaj.060218"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0215","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1439-0272.1988.tb01058.x","article-title":"Correlation Between Defects in Chromatin Condensation of Human Spermatozoa Stained by Aniline Blue and Semen Characteristics","volume":"20","author":"Dadoune","year":"2010","journal-title":"Andrologia"},{"issue":"6","key":"10.1016\/j.ejogrb.2021.10.027_b0220","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1365-2605.1990.tb01052.x","article-title":"Aniline blue staining as a marker of sperm chromatin defects associated with different semen characteristics discriminates between proven fertile and suspected infertile men","volume":"13","author":"AUGER","year":"1990","journal-title":"Int J Androl"},{"issue":"6","key":"10.1016\/j.ejogrb.2021.10.027_b0225","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1093\/humrep\/del019","article-title":"The sperm chromatin structure assay as a diagnostic tool in the human fertility clinic","volume":"21","author":"Boe-Hansen","year":"2006","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0230","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/S1472-6483(10)60887-5","article-title":"Antioxidants to reduce sperm DNA fragmentation: an unexpected adverse effect","volume":"14","author":"M\u00e9n\u00e9zo","year":"2007","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0235","doi-asserted-by":"crossref","first-page":"e221","DOI":"10.1111\/j.1365-2605.2009.00995.x","article-title":"Sperm chromatin structure assay as an independent predictor of fertility in vivo: A case-control study","volume":"33","author":"Giwercman","year":"2010","journal-title":"Int J Androl"},{"issue":"6","key":"10.1016\/j.ejogrb.2021.10.027_b0240","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/humrep\/16.6.1191","article-title":"Assessment of DNA integrity and morphology of ejaculated spermatozoa from fertile and infertile men before and after cryopreservation","volume":"16","author":"Donnelly","year":"2001","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0245","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.fertnstert.2006.01.047","article-title":"Effect of cryopreservation on sperm apoptotic deoxyribonucleic acid fragmentation in patients with oligozoospermia","volume":"86","author":"de Paula","year":"2006","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0250","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/j.1939-4640.2001.tb02225.x","article-title":"Cryopreservation-Thawing of fractionated human spermatozoa is associated with membrane phosphatidylserine externalization and not DNA fragmentation","volume":"22","author":"Duru","year":"2001","journal-title":"J Androl"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0255","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1095\/biolreprod.104.028811","article-title":"Cryoprotectant-Free Cryopreservation of Human Spermatozoa by Vitrification and Freezing in Vapor: Effect on Motility, DNA Integrity, and Fertilization Ability","volume":"71","author":"Isachenko","year":"2004","journal-title":"Biol Reprod"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0260","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/humrep\/deh194","article-title":"DNA integrity and motility of human spermatozoa after standard slow freezing versus cryoprotectant-free vitrification","volume":"19","author":"Isachenko","year":"2004","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0265","first-page":"1682","article-title":"Effect of sperm storage and selection techniques on sperm parameters","volume":"78","author":"Yeste","year":"2017","journal-title":"Cryobiology"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0270","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0015-0282(97)00536-0","article-title":"Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection","volume":"69","author":"Lopes","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0275","doi-asserted-by":"crossref","unstructured":"Muratori M, Piomboni P, Baldi E, Filimberti E, Pecchioli P, Moretti E, vd. Functional and ultrastructural features of DNA-fragmented human sperm. J Androl 21(6):903\u201312.","DOI":"10.1002\/j.1939-4640.2000.tb03421.x"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0280","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/humrep\/deh024","article-title":"Relationship between ROS production, apoptosis and DNA denaturation in spermatozoa from patients examined for infertility","volume":"19","author":"Moustafa","year":"2004","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0285","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0891-5849(99)00234-8","article-title":"Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility","volume":"28","author":"Shen","year":"2000","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0290","doi-asserted-by":"crossref","unstructured":"Irvine DS, Twigg JP, Gordon EL, Fulton N, Milne PA, Aitken RJ. DNA integrity in human spermatozoa: relationships with semen quality. J Androl. 21(1):33\u201344.","DOI":"10.1002\/j.1939-4640.2000.tb03273.x"},{"issue":"5","key":"10.1016\/j.ejogrb.2021.10.027_b0295","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1093\/humrep\/17.5.1266","article-title":"Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality","volume":"17","author":"Shen","year":"2002","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2021.10.027_b0300","first-page":"115","article-title":"Evaluation of nuclear DNA damage in human spermatozoa in men opting for assisted reproduction","volume":"127","author":"Shamsi","year":"2008","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0305","doi-asserted-by":"crossref","unstructured":"Andrabi SMH. Mammalian sperm chromatin structure and assessment of DNA fragmentation. C. 24, Journal of Assisted Reproduction and Genetics. Springer; 2007. s. 561\u20139.","DOI":"10.1007\/s10815-007-9177-y"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0310","doi-asserted-by":"crossref","unstructured":"Cocuzza M, Sikka SC, Athayde KS, Agarwal A. Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis. Int Braz J Urol 33(5):603\u201321.","DOI":"10.1590\/S1677-55382007000500002"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0315","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0015-0282(03)00756-8","article-title":"Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility","volume":"80","author":"Wang","year":"2003","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0320","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0015-0282(97)00236-7","article-title":"Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients","volume":"68","author":"Kodama","year":"1997","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.ejogrb.2021.10.027_b0325","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.fertnstert.2007.05.005","article-title":"The significance of sperm DNA oxidation in embryo development and reproductive outcome in an oocyte donation program: a new model to study a male infertility prognostic factor","volume":"89","author":"Meseguer","year":"2008","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.ejogrb.2021.10.027_b0330","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/j.fertnstert.2006.03.053","article-title":"Effect of sperm glutathione peroxidases 1 and 4 on embryo asymmetry and blastocyst quality in oocyte donation cycles","volume":"86","author":"MESEGUER","year":"2006","journal-title":"Fertil Steril"},{"issue":"13","key":"10.1016\/j.ejogrb.2021.10.027_b0335","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.ejca.2005.05.009","article-title":"Curcumin: The story so far","volume":"41","author":"Sharma","year":"2005","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0340","doi-asserted-by":"crossref","unstructured":"Aggarwal BB, Sundaram C, Malani N, Ichikawa H. Curcumin: The Indian solid gold. C. 595, Advances in Experimental Medicine and Biology. Boston, MA: Springer US; 2007. s. 1\u201375.","DOI":"10.1007\/978-0-387-46401-5_1"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0345","doi-asserted-by":"crossref","unstructured":"Corson TW, Crews CM. Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials. C. 130, Cell. Cell Press; 2007. s. 769\u201374.","DOI":"10.1016\/j.cell.2007.08.021"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0350","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1440-1681.2011.05648.x","article-title":"Discovery of curcumin, a component of golden spice, and its miraculous biological activities","volume":"39","author":"Gupta","year":"2012","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0355","doi-asserted-by":"crossref","first-page":"504","DOI":"10.2174\/1389200211314040012","article-title":"Plasma Proteins Interaction with Curcumin Nanoparticles: Implications in Cancer Therapeutics","volume":"14","author":"Yallapu","year":"2013","journal-title":"Curr Drug Metab"},{"issue":"11","key":"10.1016\/j.ejogrb.2021.10.027_b0360","first-page":"1994","article-title":"Curcumin Nanomedicine: A Road to Cancer Therapeutics","volume":"19","author":"Yallapu","year":"2013","journal-title":"Curr Pharm Des"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0365","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1096\/fj.13-235440","article-title":"Unexpected low-dose toxicity of the universal solvent DMSO","volume":"28","author":"Galvao","year":"2014","journal-title":"FASEB J"},{"issue":"1-2","key":"10.1016\/j.ejogrb.2021.10.027_b0370","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3727\/215517915X689100","article-title":"Cryopreservation of Adipose-Derived Mesenchymal Stem Cells","volume":"8","author":"Miyagi-Shiohira","year":"2015","journal-title":"Cell Med"},{"issue":"1-2","key":"10.1016\/j.ejogrb.2021.10.027_b0375","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0378-5173(02)00323-X","article-title":"Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stability","volume":"244","author":"T\u00f8nnesen","year":"2002","journal-title":"Int J Pharm"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0380","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.ijbiomac.2015.09.026","article-title":"Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review","volume":"81","author":"Mahmood","year":"2015","journal-title":"Int J Biol Macromol"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0385","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1080\/14787210.2020.1730815","article-title":"Curcumin and curcumin-loaded nanoparticles: antipathogenic and antiparasitic activities","volume":"18","author":"Rai","year":"2020","journal-title":"Expert Rev Anti Infect Ther Nisan"},{"issue":"3","key":"10.1016\/j.ejogrb.2021.10.027_b0390","first-page":"514","article-title":"Curcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: A randomized clinical trial","volume":"32","author":"Javadi","year":"2017","journal-title":"Phyther Res"},{"issue":"4","key":"10.1016\/j.ejogrb.2021.10.027_b0395","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.3390\/ijms13044655","article-title":"Injurious effects of curcumin on maturation of mouse oocytes, fertilization and fetal development via apoptosis","volume":"13","author":"Chen","year":"2012","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0400","doi-asserted-by":"crossref","unstructured":"Chen C-C, Hsieh M-S, Hsuuw Y-D, Huang F-J, Chan W-H. Hazardous Effects of Curcumin on Mouse Embryonic Development through a Mitochondria-Dependent Apoptotic Signaling Pathway. C. 11, Int J Mol Sci; 2010.","DOI":"10.3390\/ijms11082839"},{"issue":"1","key":"10.1016\/j.ejogrb.2021.10.027_b0405","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejogrb.2012.09.010","article-title":"Effect of curcumin on in vitro early post-implantation stages of mouse embryo development","volume":"166","author":"Huang","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol Ocak"},{"key":"10.1016\/j.ejogrb.2021.10.027_b0410","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.anireprosci.2017.05.001","article-title":"Direct effect of curcumin on porcine ovarian cell functions","volume":"182","author":"K\u00e1dasi","year":"2017","journal-title":"Anim Reprod Sci"},{"issue":"6","key":"10.1016\/j.ejogrb.2021.10.027_b0415","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/ptr.6054","article-title":"Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review","volume":"32","author":"Soleimani","year":"2018","journal-title":"Phytother Res Haziran"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211521005248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211521005248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:55:20Z","timestamp":1759557320000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211521005248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":83,"alternative-id":["S0301211521005248"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2021.10.027","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of curcumin on sperm parameters after the cryopreservation","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2021.10.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}