{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T05:53:42Z","timestamp":1783749222565,"version":"3.55.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.ejogrb.2022.01.010","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:03:20Z","timestamp":1642032200000},"page":"164-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The role of serum netrin-1 level in the detection of early-onset preeclampsia"],"prefix":"10.1016","volume":"270","author":[{"given":"Zekiye Soykan","family":"Sert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2022.01.010_b0005","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.preghy.2019.03.011","article-title":"Role of plasma PlGF, PDGF-AA, ANG-1, ANG-2, and the ANG-1\/ANG-2 ratio as predictors of preeclampsia in acohort of pregnant women","volume":"16","author":"Machado","year":"2019","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ejogrb.2022.01.010_b0010","unstructured":"American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 202: Gestational hypertension and preeclampsia. Obstet Gynecol 2019; 133 (1): e1-e25."},{"issue":"5","key":"10.1016\/j.ejogrb.2022.01.010_b0015","doi-asserted-by":"crossref","first-page":"523.e1","DOI":"10.1016\/j.ajog.2017.02.015","article-title":"Effect of early-onset preeclampsia on cardiovascular risk in the fifth decade of life","volume":"216","author":"Bokslag","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2022.01.010_b0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jri.2019.07.004","article-title":"The two-stage placental model of preeclampsia: an update","volume":"134-135","author":"Staff","year":"2019","journal-title":"J Reprod Immunol"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.01.010_b0025","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3109\/10641955.2016.1143486","article-title":"Comparison of indications of pregnancy termination and prognosis of mothers and neonates in early- and late-onset preeclampsia","volume":"35","author":"Ni","year":"2016","journal-title":"Hypertens Pregnancy"},{"issue":"46","key":"10.1016\/j.ejogrb.2022.01.010_b0030","doi-asserted-by":"crossref","first-page":"16210","DOI":"10.1073\/pnas.0405984101","article-title":"The axonal attractant netrin-1 is an angiogenic factor","volume":"101","author":"Park","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"10.1016\/j.ejogrb.2022.01.010_b0035","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.4161\/cc.9.8.11197","article-title":"Netrin-1 role in angiogenesis: to be or not to be a pro-angiogenic factor?","volume":"9","author":"Castets","year":"2010","journal-title":"Cell Cycle"},{"issue":"8","key":"10.1016\/j.ejogrb.2022.01.010_b0040","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.placenta.2011.04.003","article-title":"Effects of netrin-1 and netrin-1 knockdown onhuman umbilical vein endothelial cells and angiogenesis of rat placenta","volume":"32","author":"Xie","year":"2011","journal-title":"Placenta"},{"issue":"10-11-12","key":"10.1016\/j.ejogrb.2022.01.010_b0045","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1387\/ijdb.103276md","article-title":"Hypoxiainducible factor 1 controls the expression of the uncoordinated-5-B receptor, but not of netrin-1, in first trimester human placenta","volume":"55","author":"Dakouane-Giudicelli","year":"2011","journal-title":"Int J Dev Biol"},{"issue":"6","key":"10.1016\/j.ejogrb.2022.01.010_b0050","first-page":"150","article-title":"Determination of netrin-1 levels in patients that applied to emergency department with stroke and its effects on survival for 6 months","volume":"2","author":"Ivelik","year":"2014","journal-title":"Am J Intern Med"},{"issue":"4","key":"10.1016\/j.ejogrb.2022.01.010_b0055","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1161\/STROKEAHA.118.024631","article-title":"Increased serum netrin-1 Is associated with improved prognosis of ischemic stroke: an observational study from CATIS","volume":"50","author":"Guo","year":"2019","journal-title":"Stroke"},{"issue":"12","key":"10.1016\/j.ejogrb.2022.01.010_b0060","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1080\/15563650.2020.1743302","article-title":"Serum netrin-1 levels at presentation and delayed neurological sequelae in unintentional carbon monoxide poisoning","volume":"58","author":"Kokulu","year":"2020","journal-title":"Clin Toxicol (Phila)"},{"key":"10.1016\/j.ejogrb.2022.01.010_b0065","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/HJH.0b013e3282f1a953","article-title":"Non-proteinuric pre-eclampsia: a novel risk indicator in women with gestational hypertension","volume":"26","author":"Homer","year":"2008","journal-title":"J Hypertens"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.01.010_b0070","doi-asserted-by":"crossref","first-page":"481.e1","DOI":"10.1016\/j.ajog.2008.07.048","article-title":"Diagnosis and management of atypical preeclampsia-eclampsia","volume":"200","author":"Sibai","year":"2009","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2022.01.010_b0075","unstructured":"North RA, Ferrier C, Long D, Townend K, Kincaid-Smith P. Uterine artery Doppler flow velocity waveforms in the second trimester for the prediction of preeclampsia and fetal growth retardation. Obstet Gynecol 1994; 83(3): 378\u201386."},{"issue":"5","key":"10.1016\/j.ejogrb.2022.01.010_b0080","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/HYPERTENSIONAHA.119.13360","article-title":"Predictive performance of PlGF (placental growth factor) for screening preeclampsia in asymptomatic women","volume":"74","author":"Agrawal","year":"2019","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.01.010_b0085","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000341264","article-title":"Competing risks model in early screening for preeclampsia by biophysical and biochemical markers","volume":"33","author":"Akolekar","year":"2013","journal-title":"Fetal Diagn Ther"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.01.010_b0090","first-page":"69","article-title":"Placental-specific sFLT-1: role in pre-eclamptic pathophysiology and its translational possibilities for clinical prediction and diagnosis","volume":"23","author":"Palmer","year":"2017","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.ejogrb.2022.01.010_b0095","first-page":"1","article-title":"Serum netrin-1 and urinary KIM-1 levels as potential biomarkers for the diagnosis of early preeclampsia","author":"Berenji","year":"2021","journal-title":"J Obstet Gynaecol"},{"issue":"9","key":"10.1016\/j.ejogrb.2022.01.010_b0100","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1080\/14767058.2016.1201471","article-title":"Maternal serum netrin-1 levels as a new biomarker of preeclampsia","volume":"30","author":"\u00c7ekmez","year":"2017","journal-title":"J Matern Fetal Neonatal Med"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522000100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522000100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:56:19Z","timestamp":1759557379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211522000100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":20,"alternative-id":["S0301211522000100"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.01.010","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of serum netrin-1 level in the detection of early-onset preeclampsia","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}