{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T16:52:51Z","timestamp":1781801571538,"version":"3.54.5"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ejogrb.2022.08.002","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T11:46:32Z","timestamp":1659699992000},"page":"32-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Intracavitary physiotherapy combined with acupuncture mediated AMPK\/mTOR signalling to improve endometrial receptivity in patients with thin endometrium"],"prefix":"10.1016","volume":"277","author":[{"given":"Yinghua","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijuan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conghui","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ejogrb.2022.08.002_b0005","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13224-016-0929-4","article-title":"Endometrial polyps and subfertility","volume":"67","author":"Al Chami","year":"2017","journal-title":"J Obstet Gynaecol India"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.08.002_b0010","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ygyno.2015.05.027","article-title":"Cardiorespiratory fitness in survivors of cervical, endometrial, and ovarian cancers: The cooper center longitudinal study","volume":"138","author":"Peel","year":"2015","journal-title":"Gynecol Oncol"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.08.002_b0015","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/ijgo.13160","article-title":"Low-dose aspirin improves endometrial receptivity in the midluteal phase in unexplained recurrent pregnancy loss","volume":"150","author":"Wang","year":"2020","journal-title":"Int J Gynaecol Obstet"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.08.002_b0020","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF01239224","article-title":"A prospective study of echographic endometrial characteristics and pregnancy rates during hormonal replacement cycles","volume":"10","author":"Alam","year":"1993","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0025","doi-asserted-by":"crossref","unstructured":"G.S. Basir W.-S. O W.W.K. So E.H.Y. Ng P.C. Ho Evaluation of cycle-to-cycle variation of endometrial responsiveness using transvaginal sonography in women undergoing assisted reproduction Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 19 5 2002 484 489.","DOI":"10.1046\/j.1469-0705.2002.00685.x"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.08.002_b0030","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.fertnstert.2006.11.089","article-title":"Changes in measured endometrial thickness predict in vitro fertilization success","volume":"88","author":"McWilliams","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0035","doi-asserted-by":"crossref","unstructured":"Y. Wang Y. Zhu Y. Sun W. Di M. Qiu Y. Kuang et al. Ideal embryo transfer position and endometrial thickness in IVF embryo transfer treatment International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 143 3 2018 282 288.","DOI":"10.1002\/ijgo.12681"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.08.002_b0040","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/GCO.0b013e328302143c","article-title":"Thin endometrium in assisted reproductive technology","volume":"20","author":"Senturk","year":"2008","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.08.002_b0045","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s10815-018-1130-8","article-title":"In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration","volume":"35","author":"Aghajanova","year":"2018","journal-title":"J Assist Reprod Genet"},{"issue":"4","key":"10.1016\/j.ejogrb.2022.08.002_b0050","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.fertnstert.2008.01.029","article-title":"Pathophysiologic features of \u201cthin\u201d endometrium","volume":"91","author":"Miwa","year":"2009","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.08.002_b0055","doi-asserted-by":"crossref","first-page":"614","DOI":"10.3390\/ijms18030614","article-title":"Myocardial ischemic postconditioning promotes autophagy against ischemia reperfusion injury via the activation of the nNOS\/AMPK\/mTOR Pathway","volume":"18","author":"Hao","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"11","key":"10.1016\/j.ejogrb.2022.08.002_b0060","doi-asserted-by":"crossref","first-page":"7376","DOI":"10.1002\/jcp.30408","article-title":"AMPK\/mTOR downregulated autophagy enhances aberrant endometrial decidualization in folate-deficient pregnant mice","volume":"236","author":"Zhang","year":"2021","journal-title":"J Cell Physiol"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.08.002_b0065","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/dvdy.1209","article-title":"Maternal Hoxa10 is required for pinopod formation in the development of mouse uterine receptivity to embryo implantation","volume":"222","author":"Bagot","year":"2001","journal-title":"Dev Dyn"},{"issue":"6","key":"10.1016\/j.ejogrb.2022.08.002_b0070","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1095\/biolreprod57.6.1338","article-title":"A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes","volume":"57","author":"Taylor","year":"1997","journal-title":"Biol Reprod"},{"issue":"9","key":"10.1016\/j.ejogrb.2022.08.002_b0075","first-page":"925","article-title":"Acupuncture at \u201cseven acupoints on neck\u201d for cervical spondylosis of vertebral artery type","volume":"38","author":"Wang","year":"2018","journal-title":"Zhongguo Zhen Jiu"},{"issue":"4","key":"10.1016\/j.ejogrb.2022.08.002_b0080","first-page":"451","article-title":"Research progress of acupuncture and moxibustion for endometrial receptivity in recent 10 years","volume":"38","author":"Dai","year":"2018","journal-title":"Zhongguo Zhen Jiu"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.08.002_b0085","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00404-014-3382-6","article-title":"Intracavitary physiotherapy is not inferior to endometrial scratching in patients with recurrent implantation failure","volume":"291","author":"Zhang","year":"2015","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0090","unstructured":"Mao ZY, Feng H, Huang DMi(2017)Effect of pelvic floor biomimetic electrical stimulation on postpartum uterine involution.Chinese Journal of Practical Gynecology and Obstetrics 33(10) : 1074-1076."},{"issue":"2","key":"10.1016\/j.ejogrb.2022.08.002_b0095","first-page":"51","article-title":"Zishen Huoxue prescription can improve the kidney deficiency and blood stasis of rats with coronary heart disease Proteomic study of ischemic myocardium","volume":"35","author":"Liu","year":"2017","journal-title":"Chinese Archives of Traditional Chinese Medicine"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0100","first-page":"50","article-title":"Metabolomics research on time-selected combination of Liuwei Dihuang and Jinkui Shenqi pills in treating kidney deficiency and aging by chemometric methods. Chemometrics and Intelligent","volume":"130","author":"Zhang","year":"2014","journal-title":"Laboratory"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0105","article-title":"Comparative analysis of compatibility influence on invigorating blood circulation for combined use of panax notoginseng saponins and aspirin using metabolomics approach","volume":"12","author":"Sun","year":"2021","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0110","doi-asserted-by":"crossref","first-page":"6030929","DOI":"10.1155\/2018\/6030929","article-title":"Difference of liver and kidney metabolic profiling in chronic atrophic gastritis rats between acupuncture and moxibustion treatment","volume":"2018","author":"He","year":"2018","journal-title":"Evid Based Complement Alternat Med"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.08.002_b0115","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrm.2017.95","article-title":"AMPK: guardian of metabolism and mitochondrial homeostasis","volume":"19","author":"Herzig","year":"2018","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"6","key":"10.1016\/j.ejogrb.2022.08.002_b0120","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3390\/antiox9060525","article-title":"The AMP-activated protein kinase plays a role in antioxidant defense and regulation of vascular inflammation","volume":"9","author":"Jansen","year":"2020","journal-title":"Antioxidants (Basel)"},{"issue":"7","key":"10.1016\/j.ejogrb.2022.08.002_b0125","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.3390\/ijms21072428","article-title":"Activation of AMPK under hypoxia: many roads leading to Rome","volume":"21","author":"Dengler","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0130","doi-asserted-by":"crossref","first-page":"692","DOI":"10.3389\/fendo.2019.00692","article-title":"Role of mTOR signaling in female reproduction","volume":"10","author":"Guo","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"10.1016\/j.ejogrb.2022.08.002_b0135","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/ng1362","article-title":"Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease","volume":"36","author":"Ravikumar","year":"2004","journal-title":"Nat Genet"},{"key":"10.1016\/j.ejogrb.2022.08.002_b0140","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s11658-018-0088-y","article-title":"Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis","volume":"23","author":"Gwangwa","year":"2018","journal-title":"Cell Mol Biol Lett"},{"issue":"1\u20132","key":"10.1016\/j.ejogrb.2022.08.002_b0145","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.cell.2012.12.016","article-title":"Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy","volume":"152","author":"Kim","year":"2013","journal-title":"Cell"},{"issue":"34","key":"10.1016\/j.ejogrb.2022.08.002_b0150","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.3748\/wjg.v26.i34.5101","article-title":"Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation","volume":"26","author":"Fern\u00e1ndez-Ramos","year":"2020","journal-title":"World J Gastroenterol"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.08.002_b0155","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s12192-016-0715-3","article-title":"The influence of oxidative stress and autophagy cross regulation on pregnancy outcome","volume":"21","author":"de Andrade Ramos","year":"2016","journal-title":"Cell Stress Chaperones"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.08.002_b0160","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s12192-015-0609-9","article-title":"Interaction between the inducible 70-kDa heat shock protein and autophagy: effects on fertility and pregnancy","volume":"20","author":"Sisti","year":"2015","journal-title":"Cell Stress Chaperones"},{"issue":"4","key":"10.1016\/j.ejogrb.2022.08.002_b0165","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00109-019-01849-y","article-title":"Endometrial autophagy is essential for embryo implantation during early pregnancy","volume":"98","author":"Su","year":"2020","journal-title":"J Mol Med (Berl)"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522004596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522004596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:57:27Z","timestamp":1759557447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211522004596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":33,"alternative-id":["S0301211522004596"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.08.002","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intracavitary physiotherapy combined with acupuncture mediated AMPK\/mTOR signalling to improve endometrial receptivity in patients with thin endometrium","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}