{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:02:26Z","timestamp":1777579346545,"version":"3.51.4"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015034","name":"Shahid Sadoughi University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015034","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ejogrb.2022.09.027","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T02:15:38Z","timestamp":1664504138000},"page":"72-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The effect of androgen administration on in vitro fertilization outcome in poor responders undergoing ovarian stimulation with microdose protocol: A randomized clinical trial"],"prefix":"10.1016","volume":"279","author":[{"given":"Abbas","family":"Aflatoonain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lida","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robabe","family":"Hosseinisadat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ejogrb.2022.09.027_b0005","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.fertnstert.2015.09.038","article-title":"Microdose flare protocol with interrupted follicle stimulating hormone and added androgen for poor responders\u2014an observational pilot study","volume":"105","author":"Mitri","year":"2016","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.09.027_b0010","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.rbmo.2012.07.011","article-title":"Effects of transdermal testosterone in poor responders undergoing IVF: systematic review and meta-analysis","volume":"25","author":"Gonz\u00e1lez-Comadran","year":"2012","journal-title":"Reproductive Biomed Online"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.09.027_b0015","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/humrep\/dew028","article-title":"Transdermal testosterone pretreatment in poor responders undergoing ICSI: a randomized clinical trial","volume":"31","author":"Bosdou","year":"2016","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.09.027_b0020","first-page":"101","article-title":"Letrozole+ GnRH antagonist stimulation protocol in poor ovarian responders undergoing intracytoplasmic sperm injection cycles: an RCT","volume":"15","author":"Ebrahimi","year":"2017","journal-title":"Int J Reprod BioMed"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.09.027_b0025","doi-asserted-by":"crossref","first-page":"4219","DOI":"10.3892\/mmr.2015.3904","article-title":"Recombinant LH supplementation during IVF cycles with a GnRH-antagonist in estimated poor responders: a cross-matched pilot investigation of the optimal daily dose and timing","volume":"12","author":"Gizzo","year":"2015","journal-title":"Mol Med Rep"},{"issue":"7","key":"10.1016\/j.ejogrb.2022.09.027_b0030","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/1043-2760(92)90125-K","article-title":"Intraovarian regulation peptidergic signaling systems","volume":"3","author":"Adashi","year":"1992","journal-title":"Trends Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.09.027_b0035","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/humupd\/dmg007","article-title":"Clinical management of low ovarian response to stimulation for IVF: a systematic review","volume":"9","author":"Tarlatzis","year":"2003","journal-title":"Human Reprod Update"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.09.027_b0040","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1677\/joe.0.1360525","article-title":"The effects of dexamethasone treatment on immunoreactive and bioactive insulin-like growth factors (IGFs) and IGF-binding proteins in normal male volunteers","volume":"136","author":"Miell","year":"1993","journal-title":"J Endocrinol"},{"issue":"4","key":"10.1016\/j.ejogrb.2022.09.027_b0045","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0015-0282(99)00607-X","article-title":"Periovulatory human oocytes, cumulus cells, and ovarian leukocytes express type 1 but not type 2 11\u03b2-hydroxysteroid dehydrogenase RNA","volume":"73","author":"Smith","year":"2000","journal-title":"Fertil Steril"},{"issue":"7","key":"10.1016\/j.ejogrb.2022.09.027_b0050","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1007\/s43032-021-00483-9","article-title":"Effects of intraovarian injection of autologous platelet-rich plasma on ovarian rejuvenation in poor responders and women with primary ovarian insufficiency","volume":"28","author":"Aflatoonian","year":"2021","journal-title":"Reprod Sci"},{"issue":"7","key":"10.1016\/j.ejogrb.2022.09.027_b0055","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1093\/humrep\/del052","article-title":"Pretreatment with transdermal testosterone may improve ovarian response to gonadotrophins in poor-responder IVF patients with normal basal concentrations of FSH","volume":"21","author":"Balasch","year":"2006","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.09.027_b0060","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.fertnstert.2010.07.1077","article-title":"The effect of transdermal testosterone gel pretreatment on controlled ovarian stimulation and IVF outcome in low responders","volume":"95","author":"Kim","year":"2011","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.09.027_b0065","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/humrep\/dei481","article-title":"Effects of transdermal testosterone application on the ovarian response to FSH in poor responders undergoing assisted reproduction technique\u2014a prospective, randomized, double-blind study","volume":"21","author":"Massin","year":"2006","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2022.09.027_b0070","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/humrep\/den428","article-title":"Transdermal testosterone may improve ovarian response to gonadotrophins in low-responder IVF patients: a randomized, clinical trial","volume":"24","author":"Fabregues","year":"2009","journal-title":"Hum Reprod"},{"issue":"12","key":"10.1016\/j.ejogrb.2022.09.027_b0075","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1080\/09513590.2017.1332586","article-title":"The effectiveness of transdermal testosterone gel 1% (androgel) for poor responders undergoing in vitro fertilization","volume":"33","author":"Doan","year":"2017","journal-title":"Gynecol Endocrinol"},{"issue":"5","key":"10.1016\/j.ejogrb.2022.09.027_b0080","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1471-0528.1997.tb11525.x","article-title":"Assisted conception following poor ovarian response to gonadotrophin stimulation","volume":"104","author":"Keay","year":"1997","journal-title":"BJOG: Int J Obstetr Gynaecol"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.09.027_b0085","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/humrep\/dep442","article-title":"Effects of exogenous testosterone supplementation in gonadotrophin stimulated cycles","volume":"25","author":"Sipe","year":"2010","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2022.09.027_b0090","doi-asserted-by":"crossref","first-page":"e221","DOI":"10.1016\/j.fertnstert.2014.07.752","article-title":"The combination of dhea, transdermal testosterone and growth hormone as an adjuvant therapy in assisted reproductive technology in patients with dor below 40 years of age","volume":"102","author":"Haydardedeoglu","year":"2014","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ejogrb.2022.09.027_b0095","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/jrms.JRMS_864_17","article-title":"The effect of testosterone gel on fertility outcomes in women with a poor response in in vitro fertilization cycles: a pilot randomized clinical trial","volume":"23","author":"Saharkhiz","year":"2018","journal-title":"J Res Med Sci"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522005292?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211522005292?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:58:12Z","timestamp":1759557492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211522005292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":19,"alternative-id":["S0301211522005292"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.09.027","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of androgen administration on in vitro fertilization outcome in poor responders undergoing ovarian stimulation with microdose protocol: A randomized clinical trial","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2022.09.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}