{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T08:19:18Z","timestamp":1768724358429,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["847482"],"award-info":[{"award-number":["847482"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.ejogrb.2023.11.018","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T19:00:18Z","timestamp":1700074818000},"page":"158-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Effects of physical activity on placental analytes in nulliparous persons"],"prefix":"10.1016","volume":"292","author":[{"given":"Allison E.","family":"Whorton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy Y.","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6568-0201","authenticated-orcid":false,"given":"Anna","family":"Palatnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ejogrb.2023.11.018_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph16101840","article-title":"Effectiveness of Physical Activity Interventions on Pregnancy-Related Outcomes among Pregnant Women: A Systematic Review","volume":"16","author":"Chan","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0010","doi-asserted-by":"crossref","unstructured":"Han S, Middleton P, Crowther CA. Exercise for pregnant women for preventing gestational diabetes mellitus. Cochrane Database Syst Rev, 7: Jul 11 2012;CD009021. doi: 10.1002\/14651858.CD009021.pub2.","DOI":"10.1002\/14651858.CD009021.pub2"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0015","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000357340","article-title":"Physical activity and gestational diabetes mellitus","volume":"60","author":"van Poppel","year":"2014","journal-title":"Med Sport Sci"},{"issue":"3","key":"10.1016\/j.ejogrb.2023.11.018_b0020","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/EDE.0000000000000036","article-title":"Physical activity and the risk of preeclampsia: a systematic review and meta-analysis","volume":"25","author":"Aune","year":"2014","journal-title":"Epidemiology"},{"issue":"10","key":"10.1016\/j.ejogrb.2023.11.018_b0025","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1111\/j.1600-0412.2012.01483.x","article-title":"Exercise and physical activity in the prevention of pre-eclampsia: systematic review","volume":"91","author":"Kasawara","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"1","key":"10.1016\/j.ejogrb.2023.11.018_b0030","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12966-018-0701-5","article-title":"Patterns of leisure-time physical activity across pregnancy and adverse pregnancy outcomes","volume":"15","author":"Catov","year":"2018","journal-title":"Int J Behav Nutr Phys Act"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0035","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jad.2018.12.009","article-title":"Physical activity during pregnancy and postpartum depression: Systematic review and meta-analysis","volume":"246","author":"Nakamura","year":"2019","journal-title":"J Affect Disord"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0040","doi-asserted-by":"crossref","unstructured":"Physical Activity and Exercise During Pregnancy and the Postpartum Period: ACOG Committee Opinion, Number 804. Obstet Gynecol. 135(4): Apr 2020;e178-e188. doi: 10.1097\/AOG.0000000000003772.","DOI":"10.1097\/AOG.0000000000003772"},{"issue":"1","key":"10.1016\/j.ejogrb.2023.11.018_b0045","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12966-017-0485-z","article-title":"Sedentary behaviours during pregnancy: a systematic review","volume":"14","author":"Fazzi","year":"2017","journal-title":"Int J Behav Nutr Phys Act"},{"issue":"6","key":"10.1016\/j.ejogrb.2023.11.018_b0050","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/j.1365-3016.2004.00595.x","article-title":"Leisure-time physical activity among pregnant women in the US","volume":"18","author":"Evenson","year":"2004","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"12","key":"10.1016\/j.ejogrb.2023.11.018_b0055","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/ejcn.2011.129","article-title":"Physical activity pattern and activity energy expenditure in healthy pregnant and non-pregnant Swedish women","volume":"65","author":"Lof","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0060","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/567379","article-title":"The relationship of objectively measured physical activity and sedentary behaviour with gestational weight gain and birth weight","volume":"2014","author":"Ruifrok","year":"2014","journal-title":"J Pregnancy"},{"issue":"4","key":"10.1016\/j.ejogrb.2023.11.018_b0065","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.jsams.2011.02.006","article-title":"Exercise during pregnancy: a review of patterns and determinants","volume":"14","author":"Gaston","year":"2011","journal-title":"J Sci Med Sport"},{"issue":"3","key":"10.1016\/j.ejogrb.2023.11.018_b0070","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s10995-008-0359-8","article-title":"Perceived barriers to physical activity among pregnant women","volume":"13","author":"Evenson","year":"2009","journal-title":"Matern Child Health J"},{"issue":"10","key":"10.1016\/j.ejogrb.2023.11.018_b0075","doi-asserted-by":"crossref","first-page":"e109624","DOI":"10.1371\/journal.pone.0109624","article-title":"Physical activity level of urban pregnant women in Tianjin, China: a cross-sectional study","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0080","doi-asserted-by":"crossref","first-page":"e14710","DOI":"10.14814\/phy2.14710","article-title":"Physical activity differentially regulates VEGF, PlGF, and their receptors in the human placenta","volume":"9","author":"Bhattacharjee","year":"2021","journal-title":"Physiol Rep"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0085","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.placenta.2020.08.016","article-title":"Maternal physical activity significantly alters the placental transcriptome","volume":"100","author":"Loiselle","year":"2020","journal-title":"Placenta"},{"issue":"11","key":"10.1016\/j.ejogrb.2023.11.018_b0090","doi-asserted-by":"crossref","first-page":"3058","DOI":"10.1111\/febs.16173","article-title":"Prenatal exercise in fetal development: a placental perspective","volume":"289","author":"Chae","year":"2022","journal-title":"FEBS J"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0095","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/j.1879-3479.1976.tb00585.x","article-title":"The physical work capacity of the expectant mother and its effect on pregnancy, labor and the newborn","volume":"14","author":"Erkkola","year":"1976","journal-title":"Int J Gynaecol Obstet"},{"issue":"6","key":"10.1016\/j.ejogrb.2023.11.018_b0100","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1067\/mob.2000.107096","article-title":"Beginning regular exercise in early pregnancy: effect on fetoplacental growth","volume":"183","author":"Clapp","year":"2000","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0105","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.placenta.2014.11.015","article-title":"Prenatal physical activity and diet composition affect the expression of nutrient transporters and mTOR signaling molecules in the human placenta","volume":"36","author":"Brett","year":"2015","journal-title":"Placenta"},{"issue":"6","key":"10.1016\/j.ejogrb.2023.11.018_b0110","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/0002-9378(92)91730-X","article-title":"Effect of recreational exercise on midtrimester placental growth","volume":"167","author":"Clapp","year":"1992","journal-title":"Am J Obstet Gynecol"},{"issue":"7","key":"10.1016\/j.ejogrb.2023.11.018_b0115","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/CIRCRESAHA.118.313276","article-title":"Preeclampsia: Pathophysiology, Challenges, and Perspectives","volume":"124","author":"Rana","year":"2019","journal-title":"Circ Res"},{"issue":"8","key":"10.1016\/j.ejogrb.2023.11.018_b0120","doi-asserted-by":"crossref","first-page":"19009","DOI":"10.3390\/ijms160819009","article-title":"Angiogenesis-Related Biomarkers (sFlt-1\/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration","volume":"16","author":"Herraiz","year":"2015","journal-title":"Int J Mol Sci"},{"issue":"Suppl","key":"10.1016\/j.ejogrb.2023.11.018_b0125","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1016\/j.placenta.2013.10.020","article-title":"Review: the enigmatic role of endoglin in the placenta","volume":"35","author":"Gregory","year":"2014","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.ejogrb.2023.11.018_b0130","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/AOG.0000000000004149","article-title":"Biomarkers and the Prediction of Adverse Outcomes in Preeclampsia: A Systematic Review and Meta-analysis","volume":"137","author":"Lim","year":"2021","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0135","doi-asserted-by":"crossref","unstructured":"Haas DM, et al. A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b). Am J Obstet Gynecol. 212(4): Apr 2015;539 e1-539 e24. doi: 10.1016\/j.ajog.2015.01.019.","DOI":"10.1016\/j.ajog.2015.01.019"},{"issue":"46","key":"10.1016\/j.ejogrb.2023.11.018_b0140","doi-asserted-by":"crossref","first-page":"43799","DOI":"10.1074\/jbc.M207160200","article-title":"Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways","volume":"277","author":"Sanchez-Elsner","year":"2002","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.ejogrb.2023.11.018_b0145","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1095\/biolreprod.107.066498","article-title":"Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR","volume":"78","author":"Henry-Berger","year":"2008","journal-title":"Biol Reprod"},{"issue":"8","key":"10.1016\/j.ejogrb.2023.11.018_b0150","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.2174\/15665240113139990058","article-title":"Membrane and soluble forms of endoglin in preeclampsia","volume":"13","author":"Oujo","year":"2013","journal-title":"Curr Mol Med"},{"issue":"10","key":"10.1016\/j.ejogrb.2023.11.018_b0155","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1158\/0008-5472.CAN-09-4466","article-title":"Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis","volume":"70","author":"Hawinkels","year":"2010","journal-title":"Cancer Res"},{"issue":"5","key":"10.1016\/j.ejogrb.2023.11.018_b0160","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1161\/HYPERTENSIONAHA.112.194050","article-title":"Impact of exercise training on preeclampsia: potential preventive mechanisms","volume":"60","author":"Genest","year":"2012","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.ejogrb.2023.11.018_b0165","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1249\/01.MSS.0000147627.35139.DC","article-title":"The role of regular physical activity in preeclampsia prevention","volume":"36","author":"Weissgerber","year":"2004","journal-title":"Med Sci Sports Exerc"},{"issue":"8","key":"10.1016\/j.ejogrb.2023.11.018_b0170","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1111\/aogs.13151","article-title":"Exercise during pregnancy and risk of gestational hypertensive disorders: a systematic review and meta-analysis","volume":"96","author":"Magro-Malosso","year":"2017","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"21","key":"10.1016\/j.ejogrb.2023.11.018_b0175","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1136\/bjsports-2018-099355","article-title":"Prenatal exercise for the prevention of gestational diabetes mellitus and hypertensive disorders of pregnancy: a systematic review and meta-analysis","volume":"52","author":"Davenport","year":"2018","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.ejogrb.2023.11.018_b0180","doi-asserted-by":"crossref","unstructured":"A. Bergmann, M. Zygmunt, and J. F. Clapp, 3rd, \u201cRunning throughout pregnancy: effect on placental villous vascular volume and cell proliferation,\u201d Placenta, vol. 25, no. 8-9, pp. 694-8, Sep-Oct 2004, doi: 10.1016\/j.placenta.2004.02.005.","DOI":"10.1016\/j.placenta.2004.02.005"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0185","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0143-4004(95)90007-1","article-title":"The effects of maternal aerobic exercise on human placental development: placental volumetric composition and surface areas","volume":"16","author":"Jackson","year":"1995","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.ejogrb.2023.11.018_b0190","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s11906-017-0706-5","article-title":"Anti-angiogenesis and Preeclampsia in 2016","volume":"19","author":"Schrey-Petersen","year":"2017","journal-title":"Curr Hypertens Rep"},{"issue":"7","key":"10.1016\/j.ejogrb.2023.11.018_b0195","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1056\/NEJMoa031884","article-title":"Circulating angiogenic factors and the risk of preeclampsia","volume":"350","author":"Levine","year":"2004","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0200","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/01.grf.0000160313.82606.d7","article-title":"Circulating angiogenic factors in preeclampsia","volume":"48","author":"Levine","year":"2005","journal-title":"Clin Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0205","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a022210","article-title":"TGF-beta Signaling in Control of Cardiovascular Function","volume":"10","author":"Goumans","year":"2018","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"2","key":"10.1016\/j.ejogrb.2023.11.018_b0210","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s11010-021-04294-z","article-title":"The role of endoglin and its soluble form in pathogenesis of preeclampsia","volume":"477","author":"Margioula-Siarkou","year":"2022","journal-title":"Mol Cell Biochem"},{"issue":"6","key":"10.1016\/j.ejogrb.2023.11.018_b0215","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nm1429","article-title":"Soluble endoglin contributes to the pathogenesis of preeclampsia","volume":"12","author":"Venkatesha","year":"2006","journal-title":"Nat Med"},{"issue":"4","key":"10.1016\/j.ejogrb.2023.11.018_b0220","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1161\/HYPERTENSIONAHA.119.13763","article-title":"Combining Biomarkers to Predict Pregnancy Complications and Redefine Preeclampsia: The Angiogenic-Placental Syndrome","volume":"75","author":"Stepan","year":"2020","journal-title":"Hypertension"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211523008242?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211523008242?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T06:03:47Z","timestamp":1759557827000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211523008242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":44,"alternative-id":["S0301211523008242"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2023.11.018","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of physical activity on placental analytes in nulliparous persons","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2023.11.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}