{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:15:16Z","timestamp":1772583316246,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T00:00:00Z","timestamp":1704844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.ejogrb.2024.01.010","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T12:14:47Z","timestamp":1704802487000},"page":"58-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Prenatal counseling of an isolated fetal small head circumference during the second trimester expert ultrasound examination"],"prefix":"10.1016","volume":"294","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6977-2488","authenticated-orcid":false,"given":"Sofie C.","family":"Husen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eline F.","family":"Visser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata I.","family":"Srebniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin E.M.","family":"Diderich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-4784","authenticated-orcid":false,"given":"Irene A.L.","family":"Groenenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9gine P.M.","family":"Steegers-Theunissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attie T.J.I.","family":"Go","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2024.01.010_b0005","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/uog.5225","article-title":"New charts for ultrasound dating of pregnancy and assessment of fetal growth: longitudinal data from a population-based cohort study","volume":"31","author":"Verburg","year":"2008","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0010","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(14)61490-2","article-title":"International standards for fetal growth based on serial ultrasound measurements: the fetal growth longitudinal study of the INTERGROWTH-21st project","volume":"384","author":"Papageorghiou","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0015","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1002\/uog.7705","article-title":"Grade and symmetry of normal fetal cortical development: a longitudinal two- and three-dimensional ultrasound study","volume":"36","author":"Pistorius","year":"2010","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0020","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1086\/429930","article-title":"Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings","volume":"76","author":"Woods","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0025","first-page":"1","article-title":"Effect of head circumference in combination with facial profile line on ultrasonic diagnosis of microcephaly","author":"Li","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0030","doi-asserted-by":"crossref","unstructured":"Ultrasound screening for fetal microcephaly following Zika virus exposure. Am J Obstetr Gynecol 2016;214:B2-B4.","DOI":"10.1016\/j.ajog.2016.02.043"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0035","unstructured":"Pilu G, Malinger G. Microcephaly. Visual Encyclopedia of Ultrasound in Obstetrics and Gynecology. 2013."},{"key":"10.1016\/j.ejogrb.2024.01.010_b0040","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/uog.14745","article-title":"Whole-genome array as a first-line cytogenetic test in prenatal diagnosis","volume":"45","author":"Srebniak","year":"2015","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0045","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/ejhg.2015.193","article-title":"Prenatal SNP array testing in 1000 fetuses with ultrasound anomalies: causative, unexpected and susceptibility CNVs","volume":"24","author":"Srebniak","year":"2016","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0050","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2431-13-59","article-title":"A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants","volume":"13","author":"Fenton","year":"2013","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0055","doi-asserted-by":"crossref","first-page":"e16204","DOI":"10.2196\/16204","article-title":"PediTools electronic growth chart calculators: applications in clinical care, research, and quality improvement","volume":"22","author":"Chou","year":"2020","journal-title":"J Med Internet Res"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0060","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1136\/jmg.2008.063412","article-title":"Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome","volume":"46","author":"van Bon","year":"2009","journal-title":"J Med Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0065","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1399-0004.2012.01925.x","article-title":"Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype","volume":"83","author":"Hoppman-Chaney","year":"2013","journal-title":"Clin Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0070","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.ejmg.2011.01.008","article-title":"Clinical report: AN INTERSTITIAL deletion of 16p13.11 detected by array CGH in a patient with infantile spasms","volume":"54","author":"Balasubramanian","year":"2011","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0075","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/ejhg.2010.184","article-title":"Phenotypic manifestations of copy number variation in chromosome 16p13.11","volume":"19","author":"Nagamani","year":"2011","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0080","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ejmg.2008.07.005","article-title":"Clinical variability of the 22q11.2 duplication syndrome","volume":"51","author":"Wentzel","year":"2008","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0085","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/ng.534","article-title":"A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay","volume":"42","author":"Girirajan","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0090","doi-asserted-by":"crossref","first-page":"4068","DOI":"10.3390\/ijms16024068","article-title":"The 15q11.2 BP1-BP2 microdeletion syndrome: a review","volume":"16","author":"Cox","year":"2015","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0095","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/uog.5386","article-title":"Progression of Doppler abnormalities in intrauterine growth restriction","volume":"32","author":"Turan","year":"2008","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0100","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/uog.18815","article-title":"Severe fetal growth restriction at 26\u201332 weeks: key messages from the TRUFFLE study","volume":"50","author":"Bilardo","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0105","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/uog.15949","article-title":"Prenatal and postnatal findings in small-for-gestational-age fetuses without structural ultrasound anomalies at 18\u201324 weeks","volume":"49","author":"de Wit","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0110","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/ng0310-192","article-title":"Understanding variable expressivity in microdeletion syndromes","volume":"42","author":"Veltman","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0115","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/pd.5522","article-title":"Is it feasible to select fetuses for prenatal WES based on the prenatal phenotype?","volume":"39","author":"Diderich","year":"2019","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0120","unstructured":"Euro-Peristat. European Perinatal Health Report. Core indicators of the health and care of pregnant women and babies in Europe in 2015 - Mode of Delivery Available wwweuroperistatcom. 2018."},{"key":"10.1016\/j.ejogrb.2024.01.010_b0125","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/1471-0528.13284","article-title":"Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study","volume":"123","author":"Macfarlane","year":"2016","journal-title":"BJOG"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0130","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/uog.966","article-title":"Sex-specific antenatal reference growth charts for uncomplicated singleton pregnancies at 15\u201340 weeks of gestation","volume":"23","author":"Schw\u00e4rzler","year":"2004","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0135","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1159\/000484555","article-title":"Gender-specific antenatal growth reference charts in monochorionic twins","volume":"44","author":"Torres","year":"2018","journal-title":"Fetal Diagn Ther"},{"key":"10.1016\/j.ejogrb.2024.01.010_b0140","doi-asserted-by":"crossref","unstructured":"Hanzlik E, Gigante J. Microcephaly. Children (Basel). 2017;4.","DOI":"10.3390\/children4060047"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524000101?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524000101?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T06:03:30Z","timestamp":1759557810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211524000101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":28,"alternative-id":["S0301211524000101"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.01.010","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal counseling of an isolated fetal small head circumference during the second trimester expert ultrasound examination","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}