{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:37:43Z","timestamp":1791045463808,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.ejogrb.2024.06.020","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T18:56:50Z","timestamp":1718045810000},"page":"167-172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Enhancing endometrioma management: Diagnostic biomarkers and predictive outcomes in Ruptured vs. Non-Ruptured cases"],"prefix":"10.1016","volume":"299","author":[{"given":"Ayse Gulen","family":"Erturun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berna","family":"Dilbaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7623-3589","authenticated-orcid":false,"given":"Alperen","family":"Aksan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaprak","family":"Ustun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2024.06.020_b0005","doi-asserted-by":"crossref","unstructured":"ACOG practice bulletin. Medical management of endometriosis. Number 11, December 1999 (replaces Technical Bulletin Number 184, September 1993). Clinical management guidelines for obstetrician-gynecologists. Int J Gynaecol Obstet. 2000; 71(2): 183-96.","DOI":"10.1016\/S0020-7292(00)80034-X"},{"issue":"1","key":"10.1016\/j.ejogrb.2024.06.020_b0010","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s13048-019-0582-5","article-title":"Ovarian endometrioma - a possible finding in adolescent girls and young women: a mini-review","volume":"12","author":"Ga\u0142czy\u0144ski","year":"2019","journal-title":"J Ovarian Res"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0015","first-page":"8","article-title":"Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment","author":"Rolla","year":"2019","journal-title":"F1000Res"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0020","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.bpobgyn.2018.06.003","article-title":"Endometriosis classification according to pain symptoms: can the ASRM classification be improved?","volume":"51","author":"Andres","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"3","key":"10.1016\/j.ejogrb.2024.06.020_b0025","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/RD9.0000000000000015","article-title":"Potential impact of COVID-19 pandemic on endometriosis","volume":"6","author":"Huang","year":"2022","journal-title":"Reprod Dev Med"},{"issue":"12","key":"10.1016\/j.ejogrb.2024.06.020_b0030","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1093\/humrep\/13.12.3503","article-title":"Explosive rise of serum CA 125 following the rupture of ovarian endometrioma","volume":"13","author":"Johansson","year":"1998","journal-title":"Hum Reprod"},{"issue":"2","key":"10.1016\/j.ejogrb.2024.06.020_b0035","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1479-828X.1999.tb03392.x","article-title":"Extremely elevated serum CA125 due to endometriosis","volume":"39","author":"Kashyap","year":"1999","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"3","key":"10.1016\/j.ejogrb.2024.06.020_b0040","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.gynor.2012.05.005","article-title":"Ruptured ovarian endometrioma with an extreme rise in serum CA 125 level - A case report: Ovarian endometrioma with very high CA-125 level","volume":"2","author":"Rani","year":"2012","journal-title":"Gynecol Oncol Case Rep"},{"issue":"9","key":"10.1016\/j.ejogrb.2024.06.020_b0045","first-page":"695","article-title":"Ovarian endometrioma associated with very high serum CA-125 levels","volume":"26","author":"Shiau","year":"2003","journal-title":"Chang Gung Med J"},{"issue":"1","key":"10.1016\/j.ejogrb.2024.06.020_b0050","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0301-2115(03)00077-0","article-title":"Extremely elevated CA 125 level due to an unruptured large endometrioma","volume":"110","author":"Atabekoglu","year":"2003","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0055","doi-asserted-by":"crossref","unstructured":"Kahraman K, Ozguven I, Gungor M, Atabekoglu CS. Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported. Fertil Steril. 2007; 88(4): 968.e15-7.","DOI":"10.1016\/j.fertnstert.2006.12.076"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0060","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.cca.2015.09.019","article-title":"High CA-125 and CA19-9 levels in spontaneous ruptured ovarian endometriomas","volume":"450","author":"Dai","year":"2015","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0065","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/1477-7827-9-113","article-title":"A high sensitivity assay is more accurate than a classical assay for the measurement of plasma CRP levels in endometriosis","volume":"9","author":"Vodolazkaia","year":"2011","journal-title":"Reprod Biol Endocrinol"},{"issue":"35","key":"10.1016\/j.ejogrb.2024.06.020_b0070","doi-asserted-by":"crossref","first-page":"10805","DOI":"10.12998\/wjcc.v9.i35.10805","article-title":"Blood tests for prediction of deep endometriosis: A case-control study","volume":"9","author":"Chen","year":"2021","journal-title":"World J Clin Cases"},{"issue":"5","key":"10.1016\/j.ejogrb.2024.06.020_b0075","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2217\/whe.15.46","article-title":"Serum markers for the noninvasive diagnosis of endometriosis","volume":"11","author":"Luisi","year":"2015","journal-title":"Womens Health (Lond)"},{"issue":"3","key":"10.1016\/j.ejogrb.2024.06.020_b0080","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.tjog.2014.09.010","article-title":"Elevation of plasma D-dimer levels associated with rupture of ovarian endometriotic cysts","volume":"54","author":"Tanaka","year":"2015","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.ejogrb.2024.06.020_b0085","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0301-2115(02)00139-2","article-title":"Elevated serum CA125 and CA19-9 due to the spontaneous rupture of ovarian endometrioma","volume":"105","author":"Kurata","year":"2002","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"10.1016\/j.ejogrb.2024.06.020_b0090","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0301-2115(03)00095-2","article-title":"Elevated serum CA 125 and CA 19\u20139 due to spontaneous rupture of endometrioma [Eur J Obstet Gynecol Reprod Biol 2002;105:75\u20136]","volume":"109","author":"Atabekoglu","year":"2003","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2024.06.020_b0095","doi-asserted-by":"crossref","unstructured":"T Shuang, L Zhao, K Zhang, Y Wang, P Yin, L Guo, et al. Elevated serum CA 19-9 level, combined with D-dimer, could detect the presence of ruptured ovarian endometriosis. 2020. (Preprint) https:\/\/doi.org\/10.21203\/rs.3.rs-34066\/v1.","DOI":"10.21203\/rs.3.rs-34066\/v1"},{"issue":"7","key":"10.1016\/j.ejogrb.2024.06.020_b0100","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1080\/01443615.2020.1845634","article-title":"Evaluating hematological parameters in women with endometriosis","volume":"41","author":"Moini","year":"2021","journal-title":"J Obstet Gynaecol"},{"issue":"4","key":"10.1016\/j.ejogrb.2024.06.020_b0105","first-page":"251","article-title":"Comparison of Emergent and Elective Surgeries of Endometriomas: Is Adnexal Torsion a Concern?","volume":"21","author":"Dafna","year":"2019","journal-title":"Isr Med Assoc J"},{"issue":"12","key":"10.1016\/j.ejogrb.2024.06.020_b0110","first-page":"912","article-title":"Could hematologic parameters be useful biomarkers for the diagnosis of endometriosis?","volume":"120","author":"Turgut","year":"2019","journal-title":"Bratisl Lek Listy"},{"issue":"9","key":"10.1016\/j.ejogrb.2024.06.020_b0115","doi-asserted-by":"crossref","first-page":"e23947","DOI":"10.1002\/jcla.23947","article-title":"The diagnostic value of the combination of hemoglobin, CA199, CA125, and HE4 in endometriosis","volume":"35","author":"Chen","year":"2021","journal-title":"J Clin Lab Anal"},{"issue":"6","key":"10.1016\/j.ejogrb.2024.06.020_b0120","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/j.fertnstert.2008.03.061","article-title":"Neutrophil-to-lymphocyte ratio as an adjunct to CA-125 for the diagnosis of endometriosis","volume":"90","author":"Cho","year":"2008","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.ejogrb.2024.06.020_b0125","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1210\/er.2018-00242","article-title":"Endometriosis","volume":"40","author":"Bulun","year":"2019","journal-title":"Endocr Rev"},{"issue":"3","key":"10.1016\/j.ejogrb.2024.06.020_b0130","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.tjog.2010.05.002","article-title":"Long-term follow-up of patients surgically treated for ruptured ovarian endometriotic cysts","volume":"50","author":"Huang","year":"2011","journal-title":"Taiwan J Obstet Gynecol"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524003087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524003087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:56:09Z","timestamp":1759964169000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211524003087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":26,"alternative-id":["S0301211524003087"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.06.020","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancing endometrioma management: Diagnostic biomarkers and predictive outcomes in Ruptured vs. Non-Ruptured cases","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}