{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:58:21Z","timestamp":1781758701213,"version":"3.54.5"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.ejogrb.2024.07.003","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T17:28:39Z","timestamp":1720027719000},"page":"17-22","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Controlled ovarian stimulation leads to cardiovascular changes in patients undergoing in vitro fertilization"],"prefix":"10.1016","volume":"300","author":[{"given":"Laura","family":"Sarno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"Strina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9389-627X","authenticated-orcid":false,"given":"Paola","family":"Borrelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Palese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Angelino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Marrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonietta","family":"Perrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Maria","family":"Maruotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Stampalija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Guida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2024.07.003_b0005","doi-asserted-by":"crossref","first-page":"5861","DOI":"10.3390\/jcm11195861","article-title":"Cardiovascular function in different phases of the menstrual cycle in healthy women of reproductive age","volume":"11","author":"Kwissa","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0010","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/eci.12447","article-title":"The different role of sex hormones on female cardiovascular physiology and function: Not only oestrogens","volume":"45","author":"Salerni","year":"2015","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0015","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0002-9149(02)02405-0","article-title":"Protective effects of estrogen on the cardiovascular system","volume":"89","author":"Mendelsohn","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0020","doi-asserted-by":"crossref","first-page":"26339","DOI":"10.1074\/jbc.M414409200","article-title":"Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1","volume":"280","author":"Pedram","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0025","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1172\/JCI200111374","article-title":"A complex role for the progesterone receptor in the response to vascular injury","volume":"108","author":"Karas","year":"2001","journal-title":"J Clin Investig"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0030","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.765916","article-title":"Associations of sex hormones and hormonal status with arterial stiffness in a female sample from reproductive years to menopause","volume":"12","author":"Laakkonen","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0035","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1258\/ebm.2009.009186","article-title":"Central, peripheral and resistance arterial reactivity: fluctuates during the phases of the menstrual cycle","volume":"235","author":"Adkisson","year":"2010","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0040","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1113\/expphysiol.2012.066498","article-title":"Influence of menstrual cycle phase on muscle metaboreflex control of cardiac baroreflex sensitivity, heart rate and blood pressure in humans","volume":"98","author":"Hartwich","year":"2013","journal-title":"Exp Physiol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0045","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1210\/jcem.87.4.8406","article-title":"Menstrual cycle effects on the neurohumoral and autonomic nervous systems regulating the cardiovascular system","volume":"87","author":"Hirshoren","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0050","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1161\/CIRCULATIONAHA.114.009029","article-title":"Cardiovascular physiology of pregnancy","volume":"130","author":"Sanghavi","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0055","doi-asserted-by":"crossref","first-page":"124.e1","DOI":"10.1016\/j.ajog.2017.10.226","article-title":"Maternal hemodynamics: a method to classify hypertensive disorders of pregnancy","volume":"218","author":"Ferrazzi","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0060","doi-asserted-by":"crossref","first-page":"517.e1","DOI":"10.1016\/j.ajog.2018.02.007","article-title":"Early and late preeclampsia are characterized by high cardiac output, but in the presence of fetal growth restriction, cardiac output is low: insights from a prospective study","volume":"218","author":"Tay","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0065","doi-asserted-by":"crossref","first-page":"633.e1","DOI":"10.1016\/j.ajog.2019.06.029","article-title":"Maternal cardiac parameters can help in differentiating the clinical profile of preeclampsia and in predicting progression from mild to severe forms","volume":"221","author":"di Pasquo","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0070","doi-asserted-by":"crossref","first-page":"S954","DOI":"10.1016\/j.ajog.2020.10.024","article-title":"The placenta and preeclampsia: villain or victim?","volume":"226","author":"Melchiorre","year":"2022","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0075","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/uog.17378","article-title":"Placental syndromes: getting to the heart of the matter","volume":"49","author":"Thilaganathan","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0080","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.preghy.2020.10.001","article-title":"The impact of obesity on haemodynamic profiles of pregnant women beyond 34 weeks\u2019 gestation","volume":"22","author":"Sarno","year":"2020","journal-title":"Pregnancy Hypertens"},{"issue":"3","key":"10.1016\/j.ejogrb.2024.07.003_b0085","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00421-008-0914-4","article-title":"Modulation of heart rate variability by estrogen in young women undergoing induction of ovulation","volume":"105","author":"Weissman","year":"2008","journal-title":"Eur J Appl Physiol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0090","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.00633.2007","article-title":"Cerebral blood flow is increased during controlled ovarian stimulation","volume":"293","author":"Nevo","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0095","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S0015-0282(16)60669-6","article-title":"Noninvasive evaluation of cardiovascular hemodynamics during multiple follicular stimulation, late luteal phase and early pregnancy","volume":"51","author":"la Sala","year":"1989","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0100","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/uog.17447","article-title":"Maternal hemodynamics early in labor: a possible link with obstetric risk?","volume":"51","author":"Valensise","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0105","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S1701-2163(16)30527-8","article-title":"Perinatel outcomes of singleton pregnancies achieved by in vitro fertilization: a systematic review and meta-analysis","volume":"27","author":"McDonald","year":"2005","journal-title":"J Obstet Gynaecol Can"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0110","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.AOG.0000114989.84822.51","article-title":"Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis","volume":"103","author":"Jackson","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0115","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/humupd\/dms018","article-title":"Obstetric and perinatal outcomes in singleton pregnancies resulting from IVF\/ICSI: a systematic review and meta-analysis","volume":"18","author":"Pandey","year":"2012","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0120","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1136\/bmj.37957.560278.EE","article-title":"Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies","volume":"328","author":"Helmerhorst","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0125","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.fertnstert.2015.09.007","article-title":"Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a meta-analysis of cohort studies","volume":"105","author":"Qin","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0130","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1093\/humrep\/17.11.2897","article-title":"The course of pregnancy and delivery and the use of maternal healthcare services after standard IVF in Northern Finland 1990\u20131995","volume":"17","author":"Koivurova","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0135","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ejogrb.2020.01.033","article-title":"Acute cardiovascular changes in women undergoing in vitro fertilisation (IVF), a systematic review and meta-analysis","volume":"248","author":"Fujitake","year":"2020","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0140","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.preghy.2021.09.001","article-title":"Maternal haemodynamic profile in pregnancy after assisted reproductive technology: a pilot study","volume":"26","author":"Sarno","year":"2021","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0145","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/S0015-0282(02)03116-3","article-title":"Chronology of hemodynamic changes in asymptomatic in vitro fertilization patients and relationship with ovarian steroids and cytokines","volume":"77","author":"Manau","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0150","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1007\/s12020-013-9953-7","article-title":"Correlation between steroid hormonal levels and cardiac function in women during controlled ovarian hyperstimulation","volume":"44","author":"Li","year":"2013","journal-title":"Endocrine"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0155","first-page":"1489","article-title":"Circulatory dysfunction in asymptomatic in vitro fertilization patients. Relationship with hyperestrogenemia and activity of endogenous vasodilators","volume":"83","author":"Manau","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0160","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3109\/00365519309086627","article-title":"Effects of ovarian stimulation on blood pressure and plasma catecholamine levels","volume":"53","author":"Tollan","year":"2009","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0165","unstructured":"Uckuyu A, Ciftci CF, Ozcimen EE, Ciftci O, Toprak E, Turhan E. Effect of controlled ovarian hyperstimulation treatment on cardiac function - PubMed n.d. https:\/\/pubmed.ncbi.nlm.nih.gov\/21291037\/ (accessed May 1, 2023)."},{"key":"10.1016\/j.ejogrb.2024.07.003_b0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/hropen\/hoaa013","article-title":"A decision-making algorithm for performing or cancelling embryo transfer in patients at high risk for ovarian hyperstimulation syndrome after triggering final oocyte maturation with hCG","volume":"2020","author":"Lainas","year":"2020","journal-title":"Hum Reprod Open"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0175","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/uog.17454","article-title":"Effect of a nitric oxide donor on maternal hemodynamics in fetal growth restriction","volume":"51","author":"Tiralongo","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.preghy.2020.10.001","article-title":"The impact of obesity on haemodynamic profiles of pregnant women beyond 34 weeks\u2019 gestation","volume":"22","author":"Sarno","year":"2020","journal-title":"Pregnancy Hypertens"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0185","article-title":"Local and systemic estradiol-17 beta: effects on uterine and systemic vasodilation","volume":"256","author":"Magness","year":"1989","journal-title":"Am J Physiol"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0190","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1161\/01.HYP.37.2.651","article-title":"Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women","volume":"37","author":"Higashi","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0195","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.pharmthera.2012.03.007","article-title":"Estrogen and the cardiovascular system","volume":"135","author":"Knowlton","year":"2012","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.ejogrb.2024.07.003_b0200","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/09513590.2022.2082402","article-title":"Systemic vascular resistance may influence the outcome of in vitro fertilization","volume":"38","author":"Galanti","year":"2022","journal-title":"Gynecol Endocrinol"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524003385?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524003385?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:09:53Z","timestamp":1762456193000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211524003385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":40,"alternative-id":["S0301211524003385"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.07.003","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Controlled ovarian stimulation leads to cardiovascular changes in patients undergoing in vitro fertilization","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}