{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T23:28:07Z","timestamp":1773358087899,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.ejogrb.2024.12.056","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T17:13:14Z","timestamp":1735837994000},"page":"404-409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Cervical screening with self-sampling for postmenopausal women with molecular triage using extended genotyping and methylation"],"prefix":"10.1016","volume":"305","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2317-5738","authenticated-orcid":false,"given":"Gisela","family":"Helenius","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Lillsunde-Larsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mats G.","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malin","family":"Kaliff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lovisa","family":"Bergengren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2024.12.056_b0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0217108","article-title":"HPV-based screening for cervical cancer among women 55-59 years of age","volume":"14","author":"Bergengren","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0010","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1002\/ijc.2910630610","article-title":"Low efficiency of cytologic screening for cancer in situ of the cervix in older women","volume":"63","author":"Gustafsson","year":"1995","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0015","article-title":"Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: updated meta-analyses","volume":"363","author":"Arbyn","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0020","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1002\/ijc.33888","article-title":"Self-sampling as the principal modality for population based cervical screening: Five-year follow-up of the PaVDaG study","volume":"150","author":"Stanczuk","year":"2022","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0025","first-page":"5147","article-title":"Elderly women above screening age diagnosed with cervical cancer have a worse prognosis","volume":"34","author":"Darlin","year":"2014","journal-title":"Anticancer Res"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0030","unstructured":"Welfare, S.N.B.o.H.a., 2024. Statistikdatabas f\u00f6r cancer."},{"key":"10.1016\/j.ejogrb.2024.12.056_b0035","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/cncr.23949","article-title":"Atypical squamous cells, cannot exclude a high-grade intraepithelial lesion and its clinical significance in postmenopausal, pregnant, postpartum, and contraceptive-use patients","volume":"114","author":"Patton","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0040","unstructured":"Regional Cancer Centre, 2022. National cervical cancer prevention guidelines."},{"key":"10.1016\/j.ejogrb.2024.12.056_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/LGT.0000000000000494","article-title":"Clinical Utility of Human Papillomavirus Genotyping in Cervical Cancer Screening: A Systematic Review","volume":"24","author":"Bonde","year":"2020","journal-title":"J Low Genit Tract Dis"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0050","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jcv.2014.02.002","article-title":"Individual detection of 14 high risk human papilloma virus genotypes by the PapType test for the prediction of high grade cervical lesions","volume":"60","author":"Cuzick","year":"2014","journal-title":"J Clin Virol"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0055","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/ijc.33320","article-title":"Methylation markers FAM19A4 and miR124-2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study","volume":"148","author":"Bonde","year":"2021","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0060","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1158\/1940-6207.CAPR-14-0237","article-title":"Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2\/3 lesions","volume":"7","author":"De Strooper","year":"2014","journal-title":"Cancer Prev Res (Phila)"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0065","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ygyno.2019.06.002","article-title":"Long-term CIN3+ risk of HPV positive women after triage with FAM19A4\/miR124-2 methylation analysis","volume":"154","author":"Dick","year":"2019","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2020.03.018","article-title":"FAM19A4\/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort","volume":"27","author":"Vink","year":"2021","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0075","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/ijc.32614","article-title":"FAM19A4\/miR124-2 methylation in invasive cervical cancer: A retrospective cross-sectional worldwide study","volume":"147","author":"Vink","year":"2020","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0080","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jviromet.2019.04.015","article-title":"Increased HPV detection by the use of a pre-heating step on vaginal self-samples analysed by Aptima HPV assay","volume":"270","author":"Borgfeldt","year":"2019","journal-title":"J Virol Methods"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0085","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1001\/jama.287.16.2114","article-title":"The 2001 Bethesda System: terminology for reporting results of cervical cytology","volume":"287","author":"Solomon","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0090","unstructured":"Kurman, R.J., Cancer, I.A.f.R.o., Organization, W.H., 2014. WHO classification of tumors of female reproductive organs. International Agency for Research on Cancer, Lyon."},{"key":"10.1016\/j.ejogrb.2024.12.056_b0095","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jmoldx.2014.12.004","article-title":"Evaluation of HPV Genotyping Assays for Archival Clinical Samples","volume":"17","author":"Lillsunde Larsson","year":"2015","journal-title":"J Mol Diagnost: JMD"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0100","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/CEJ.0000000000000693","article-title":"Equal prevalence of severe cervical dysplasia by HPV self-sampling and by midwife-collected samples for primary HPV screening: a randomised controlled trial","volume":"30","author":"Hellsten","year":"2021","journal-title":"Eur J Cancer Prev"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0105","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10552-020-01278-0","article-title":"Prevalence of HPV and pathological changes among women 70 years of age, 10 years after exclusion from the Swedish cervical cancer screening program","volume":"31","author":"Bergengren","year":"2020","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0189300","article-title":"HPV prevalence and HPV-related dysplasia in elderly women","volume":"13","author":"Hermansson","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0115","article-title":"Full genotyping and FAM19A4\/miR124-2 methylation analysis in high-risk human papillomavirus-positive samples from women over 30 years participating in cervical cancer screening in \u00d6rebro","volume":"17","author":"Kaliff","year":"2022","journal-title":"Sweden PLoS One"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0120","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1002\/ijc.29824","article-title":"Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16\/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study)","volume":"138","author":"Luttmer","year":"2016","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0125","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1002\/ijc.34170","article-title":"Human papillomavirus self-sampling with mRNA testing benefits routine screening","volume":"151","author":"Auvinen","year":"2022","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ejogrb.2024.12.056_b0130","doi-asserted-by":"crossref","first-page":"381","DOI":"10.21873\/anticanres.13123","article-title":"Detection of HPV mRNA in Self-collected Vaginal Samples Among Women at 69-70 Years of Age","volume":"39","author":"Ernstson","year":"2019","journal-title":"Anticancer Res"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524007310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211524007310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T20:19:40Z","timestamp":1740341980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211524007310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":26,"alternative-id":["S0301211524007310"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.12.056","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cervical screening with self-sampling for postmenopausal women with molecular triage using extended genotyping and methylation","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2024.12.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}