{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:29:14Z","timestamp":1792794554094,"version":"4.5.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.ejogrb.2025.113976","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T15:47:42Z","timestamp":1744386462000},"page":"113976","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Probiotics in pregnancy and group B streptococcus colonization: A multicentric, randomized, placebo-controlled, double-blind study with a focus on vaginal microbioma"],"prefix":"10.1016","volume":"310","author":[{"given":"Daniela","family":"Menichini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"De Seta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore Andrea","family":"Mastrolia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Cetin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Carafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Santagni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Foschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Cerboneschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Smeazzetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Neri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Facchinetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2025.113976_b0005","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJM199604183341601","article-title":"Induction of labor compared with expectant management for prelabor rupture of the membranes at term","volume":"334","author":"Hannah","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2025.113976_b0010","series-title":"Infectious diseases of the fetus and newborn infant","article-title":"Group B streptococcal infections","author":"Baker","year":"1995"},{"key":"10.1016\/j.ejogrb.2025.113976_b0015","first-page":"68","article-title":"Prevention of perinatal group B streptococcal infection: management strategies","volume":"8","author":"Demianczuk","year":"1997","journal-title":"Can J Infect Dis"},{"key":"10.1016\/j.ejogrb.2025.113976_b0020","first-page":"1","article-title":"Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC). Prevention of perinatal group B streptococcal disease \u2013 revised guidelines from CDC","volume":"59","author":"Verani","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.ejogrb.2025.113976_b0025","unstructured":"National Institute for Health and Care Excellence. Neonatal infection: antibiotics for prevention and treatment NICE guideline. London: NICE; 2024. Available at: www.nice.org.uk\/guidance\/ng195."},{"key":"10.1016\/j.ejogrb.2025.113976_b0030","doi-asserted-by":"crossref","first-page":"10635","DOI":"10.1038\/s41598-019-46964-5","article-title":"Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants","volume":"9","author":"Tapiainen","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejogrb.2025.113976_b0035","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1136\/archdischild-2018-316659","article-title":"Effect of intrapartum antibiotics on the intestinal microbiota of infants: a systematic review","volume":"105","author":"Zimmermann","year":"2020","journal-title":"Arch Dis Child Fetal Neonatal"},{"key":"10.1016\/j.ejogrb.2025.113976_b0040","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1210\/en.2015-1177","article-title":"Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain","volume":"156","author":"Ja\u0161arevi\u0107","year":"2015","journal-title":"Endocrinology"},{"key":"10.1016\/j.ejogrb.2025.113976_b0045","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1128\/AAC.05794-11","article-title":"High rates of perinatal group B streptococcus clindamycin and erythromycin resistance in an upstate New York hospital","volume":"56","author":"Back","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ejogrb.2025.113976_b0050","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1038\/s41598-019-39625-0","article-title":"Inhibition of Candida albicans morphogenesis by chitinase from Lactobacillus rhamnosus GG","volume":"9","author":"Allonsius","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejogrb.2025.113976_b0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0161337","article-title":"Lectin-like molecules of Lactobacillus rhamnosus GG inhibit pathogenic Escherichia coli and Salmonella biofilm formation","volume":"11","author":"Petrova","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2025.113976_b0060","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.resmic.2017.04.001","article-title":"The role of lactic acid production by probiotic Lactobacillus species in vaginal health","volume":"168","author":"Tachedjian","year":"2017","journal-title":"Res Microbiol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0065","doi-asserted-by":"crossref","first-page":"4520","DOI":"10.3390\/nu14214520","article-title":"Supplementation of probiotics in pregnant women targeting group B streptococcus colonization: a systematic review and meta-analysis","volume":"14","author":"Menichini","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.ejogrb.2025.113976_b0070","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1258\/jms.2011.011023","article-title":"GBS Prevention Working Group, Emilia-Romagna. Universal antenatal screening for group B streptococcus in Emilia-Romagna","volume":"18","author":"Berardi","year":"2011","journal-title":"J Med Screen"},{"key":"10.1016\/j.ejogrb.2025.113976_b0075","first-page":"498","article-title":"Group B streptococcal colonization and serotype-specific immunity in pregnant women at delivery","volume":"96","author":"Campbell","year":"2000","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0080","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.tjog.2016.06.003","article-title":"Oral Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 to reduce group B streptococcus colonization in pregnant women: arandomized controlled trial","volume":"55","author":"Ho","year":"2016","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0085","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.838405","article-title":"A deep look at the vaginal environment during pregnancy and puerperium","volume":"12","author":"Severgnini","year":"2022","journal-title":"Front Cell Infec Microbiol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0090","doi-asserted-by":"crossref","first-page":"14095","DOI":"10.1038\/s41598-019-50410-x","article-title":"Diversity of vaginal microbiome and metabolome during genital infections","volume":"9","author":"Ceccarani","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejogrb.2025.113976_b0095","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.3390\/pathogens10101347","article-title":"Vaginal and anal microbiome during Chlamydia trachomatis infections","volume":"10","author":"Raimondi","year":"2021","journal-title":"Pathogens"},{"key":"10.1016\/j.ejogrb.2025.113976_b0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0269590","article-title":"Gardnerella vaginalisclades in pregnancy: new insights into the interactions with the vaginal microbiome","volume":"17","author":"Severgnini","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2025.113976_b0105","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.813520","article-title":"Sialidase activity in the cervicovaginal fluid is associated with changes in bacterial components of lactobacillus-deprived microbiota","volume":"11","author":"Ferreira","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0110","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/01.AOG.0000183594.45524.d2","article-title":"Adherent biofilms in bacterial vaginosis","volume":"106","author":"Swidsinski","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.113976_b0115","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1089\/mdr.2023.0202","article-title":"Antimicrobial resistance of genital mycoplasma and ureaplasma: a multicentre study over a 5-year period in Italy (2017\u20132021)","volume":"30","author":"Pavoni","year":"2024","journal-title":"Microb Drug Resist"},{"key":"10.1016\/j.ejogrb.2025.113976_b0120","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3390\/pathogens11080847","article-title":"Characterization of vaginal microbiota in third trimester premature rupture of membranes patients through 16S rDNA sequencing","volume":"11","author":"Liu","year":"2022","journal-title":"Pathogens"}],"container-title":["European Journal of Obstetrics &amp; Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525002453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525002453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T11:15:23Z","timestamp":1747653323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211525002453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":24,"alternative-id":["S0301211525002453"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.113976","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Probiotics in pregnancy and group B streptococcus colonization: A multicentric, randomized, placebo-controlled, double-blind study with a focus on vaginal microbioma","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.113976","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113976"}}