{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:28:20Z","timestamp":1793726900501,"version":"4.6.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T00:00:00Z","timestamp":1745020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.ejogrb.2025.113994","type":"journal-article","created":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T01:27:05Z","timestamp":1745112425000},"page":"113994","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Impact of Human papillomavirus 9-valent vaccine on viral clearance after surgical treatment: A single-center retrospective observational study"],"prefix":"10.1016","volume":"310","author":[{"given":"Mario","family":"Palumbo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giada","family":"Lavitola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Di Filippo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Foreste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddalena","family":"Granata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriana","family":"Imperatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Ascione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Della Corte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Bifulco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2025.113994_b0005","doi-asserted-by":"crossref","unstructured":"Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5):E359-86. doi: 10.1002\/ijc.29210. Epub 2014 Oct 9. PMID: 25220842 (2015).","DOI":"10.1002\/ijc.29210"},{"key":"10.1016\/j.ejogrb.2025.113994_b0010","doi-asserted-by":"crossref","unstructured":"Xi LF, Hughes JP, Castle PE, Edelstein ZR, Wang C, Galloway DA, et al. Viral load in the natural history of human papillomavirus type 16 infection: a nested case-control study. J Infect Dis. 2011 May 15;203(10):1425-33 (2011).","DOI":"10.1093\/infdis\/jir049"},{"key":"10.1016\/j.ejogrb.2025.113994_b0015","doi-asserted-by":"crossref","unstructured":"Illah O, Olaitan A. Updates on HPV Vaccination. Diagnostics (Basel). 2023 Jan 9;13(2):243 (2023).","DOI":"10.3390\/diagnostics13020243"},{"key":"10.1016\/j.ejogrb.2025.113994_b0020","doi-asserted-by":"crossref","unstructured":"Arbyn M, Xu L, Simoens C, Martin-Hirsch PP. Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors. Cochrane Database Syst Rev. 2018 May 9;5(5):CD009069 (2018).","DOI":"10.1002\/14651858.CD009069.pub3"},{"issue":"8","key":"10.1016\/j.ejogrb.2025.113994_b0025","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1056\/NEJMoa1405044","article-title":"Broad Spectrum HPV Vaccine Study. A 9-valent HPV vaccine against infection and intraepithelial neoplasia in women","volume":"372","author":"Joura","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejogrb.2025.113994_b0030","doi-asserted-by":"crossref","unstructured":"World Health Organization. Electronic address: Sageexecsec@who.int. Human papillomavirus vaccines: WHO position paper, May 2017-Recommendations. Vaccine 2017, 35, 5753\u20135755 (2017).","DOI":"10.1016\/j.vaccine.2017.05.069"},{"key":"10.1016\/j.ejogrb.2025.113994_b0035","unstructured":"WHO adds an HPV vaccine for single-dose use, 4 October 2024. News release. Reading time: 2 min (603 words) (2024)."},{"key":"10.1016\/j.ejogrb.2025.113994_b0040","unstructured":"Markowitz LE, Dunne EF, Saraiya M, Chesson HW, Curtis CR, Gee J, et al. Centers for Disease Control and Prevention (CDC). Human papillomavirus vaccination: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm. Rep. 2014, 63, 1\u201330, Erratum in 2014, 63, 1182 (2014)."},{"key":"10.1016\/j.ejogrb.2025.113994_b0045","doi-asserted-by":"crossref","unstructured":"Luna J, Plata M, Gonzalez M, Correa A, Maldonado I, Nossa C, et al. Long-term follow-up observation of the safety, immunogenicity, and effectiveness of Gardasil\u2122 in adult women. PLoS One. 2013 Dec 31;8(12):e83431 (2013).","DOI":"10.1371\/journal.pone.0083431"},{"key":"10.1016\/j.ejogrb.2025.113994_b0050","doi-asserted-by":"crossref","unstructured":"Skinner SR, Szarewski A, Romanowski B, Garland SM, Lazcano-Ponce E, Salmer\u00f3n J, et al. VIVIANE Study Group. Efficacy, safety, and immunogenicity of the human papillomavirus 16\/18 AS04-adjuvanted vaccine in women older than 25 years: 4-year interim follow-up of the phase 3, double-blind, randomised controlled VIVIANE study. Lancet. 2014 Dec 20;384(9961):2213-27 (2014).","DOI":"10.1016\/S0140-6736(14)60920-X"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.113994_b0055","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1002\/cam4.1155","article-title":"Ten-year immune persistence and safety of the HPV-16\/18 AS04-adjuvanted vaccine in females vaccinated at 15\u201355 years of age","volume":"2017","author":"Schwarz","year":"2017","journal-title":"Cancer Med"},{"key":"10.1016\/j.ejogrb.2025.113994_b0060","unstructured":"Gardasil 9 EPAR\u2014Product Information, EMA (Last Updated March 2021). Available online: https:\/\/www.ema.europa.eu\/en\/ documents\/product-information\/gardasil-9-epar-product-information_en.pdf (accessed on 25 April 2021) (2021)."},{"key":"10.1016\/j.ejogrb.2025.113994_b0065","doi-asserted-by":"crossref","unstructured":"Joura EA, Kyrgiou M, Bosch FX, Kesic V, Niemenen P, Redman CW, et al. Human papillomavirus vaccination: The ESGO-EFC position paper of the European society of Gynaecologic Oncology and the European Federation for colposcopy. Eur J Cancer. 2019 Jul;116:21-26 (2019).","DOI":"10.1016\/j.ejca.2019.04.032"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.113994_b0070","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ygyno.2018.08.033","article-title":"SPERANZA project: HPV vaccination after treatment for CIN2","volume":"151","author":"Ghelardi","year":"2018","journal-title":"Gynecol Oncol"},{"issue":"5","key":"10.1016\/j.ejogrb.2025.113994_b0075","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/AOG.0000000000003833","article-title":"Adjuvant Human Papillomavirus Vaccine to Reduce Recurrent Cervical Dysplasia in Unvaccinated Women: A Systematic Review and Meta-analysis","volume":"135","author":"Lichter","year":"2020","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.113994_b0080","doi-asserted-by":"crossref","unstructured":"Lehtinen M, Paavonen J, Wheeler CM, Jaisamrarn U, Garland SM, Castellsagu\u00e9 X, et al. HPV PATRICIA Study Group. Overall efficacy of HPV-16\/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial. Lancet Oncol. 2012 Jan;13(1):89-99 (2012).","DOI":"10.1016\/S1470-2045(11)70286-8"},{"key":"10.1016\/j.ejogrb.2025.113994_b0085","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez-G\u00f3mez X, Curran A, Campins M, Alemany L, Rodrigo-Pend\u00e1s J\u00c1, Borruel N, et al. Multidisciplinary, evidence-based consensus guidelines for human papillomavirus (HPV) vaccination in high-risk populations, Spain, 2016. Euro Surveill. 2019 Feb;24(7):1700857 (2019).","DOI":"10.2807\/1560-7917.ES.2019.24.7.1700857"},{"key":"10.1016\/j.ejogrb.2025.113994_b0090","unstructured":"HPV vaccine therapy in reducing high-grade cervical lesions in patients with HIV and HPV. Available at: https:\/\/clinicaltrials. gov\/ct2\/show\/NCT03284866. Retrieved June 2, 2019 (2019)."},{"issue":"2","key":"10.1016\/j.ejogrb.2025.113994_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2016.02.021","article-title":"Costa Rica HPV Vaccine Trial (CVT) Group. Impact of human papillomavirus (HPV) 16 and 18 vaccination on prevalent infections and rates of cervical lesions after excisional treatment","volume":"215","author":"Hildesheim","year":"2016","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.113994_b0100","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ygyno.2013.04.050","article-title":"Is vaccination with quadrivalent HPV vaccine after loop electrosurgical excision procedure effective in preventing recurrence in patients with high-grade cervical intraepithelial neoplasia (CIN2-3)?","volume":"130","author":"Kang","year":"2013","journal-title":"Gynecol Oncol"},{"issue":"14","key":"10.1016\/j.ejogrb.2025.113994_b0105","first-page":"125","article-title":"Minimally invasive surgery with the complementing immunotherapy in the treatment of intraepithelial neoplasia of cervix in women of child-bearing age","volume":"2011","author":"Grzes","year":"2011","journal-title":"Onkologia Polska"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.113994_b0110","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1097\/AOG.0b013e318237caf4","article-title":"The clinical meaning of a cervical intraepithelial neoplasia grade 1 biopsy","volume":"118","author":"Castle","year":"2011","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.113994_b0115","doi-asserted-by":"crossref","unstructured":"S\u00f8rbye SW, Arbyn M, Fismen S, Gutteberg TJ, Mortensen ES. HPV E6\/E7 mRNA testing is more specific than cytology in post-colposcopy follow-up of women with negative cervical biopsy. PLoS One. 2011;6(10):e26022. doi: 10.1371\/journal.pone.0026022. Epub 2011 Oct 6. PMID: 21998748; PMCID: PMC3188582.","DOI":"10.1371\/journal.pone.0026022"},{"issue":"20","key":"10.1016\/j.ejogrb.2025.113994_b0120","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","author":"World Medical Association","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.ejogrb.2025.113994_b0125","doi-asserted-by":"crossref","unstructured":"Dayyani F, Etzel CJ, Liu M, Ho CH, Lippman SM, Tsao AS. Meta-analysis of the impact of human papillomavirus (HPV) on cancer risk and overall survival in head and neck squamous cell carcinomas (HNSCC). Head Neck Oncol. 2010 Jun 29;2:15 (2010).","DOI":"10.1186\/1758-3284-2-15"},{"issue":"4","key":"10.1016\/j.ejogrb.2025.113994_b0130","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/path.4424","article-title":"Are 20 human papillomavirus types causing cervical cancer?","volume":"234","author":"Arbyn","year":"2014","journal-title":"J Pathol"},{"key":"10.1016\/j.ejogrb.2025.113994_b0135","doi-asserted-by":"crossref","unstructured":"Hemmat N, Bannazadeh Baghi H. Association of human papillomavirus infection and inflammation in cervical cancer. Pathog Dis. 2019 Jul 1;77(5):ftz048 (2019).","DOI":"10.1093\/femspd\/ftz048"},{"key":"10.1016\/j.ejogrb.2025.113994_b0140","doi-asserted-by":"crossref","unstructured":"Castle PE, Giuliano AR. Chapter 4: Genital tract infections, cervical inflammation, and antioxidant nutrients--assessing their roles as human papillomavirus cofactors. J Natl Cancer Inst Monogr. 2003;(31):29-34 (2003).","DOI":"10.1093\/oxfordjournals.jncimonographs.a003478"},{"key":"10.1016\/j.ejogrb.2025.113994_b0145","doi-asserted-by":"crossref","unstructured":"Swift BE, Wang L, Jembere N, Kupets R. Risk of Recurrence After Treatment for Cervical Intraepithelial Neoplasia 3 and Adenocarcinoma In Situ of the Cervix: Recurrence of CIN 3 and AIS of Cervix. J Low Genit Tract Dis. 2020 Jul;24(3):252-258 (2020).","DOI":"10.1097\/LGT.0000000000000542"},{"key":"10.1016\/j.ejogrb.2025.113994_b0150","doi-asserted-by":"crossref","unstructured":"Barra F, Della Corte L, Noberasco G, Foreste V, Riemma G, Di Filippo C, et al. Advances in therapeutic vaccines for treating human papillomavirus-related cervical intraepithelial neoplasia. J Obstet Gynaecol Res. 2020 Jul;46(7):989-1006 (2020).","DOI":"10.1111\/jog.14276"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.113994_b0155","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s00404-023-07087-5","article-title":"How endocervicoscopy can impact obstetric outcomes in women undergoing LEEP for CIN2\u2009+\u2009: a retrospective cohort analysis","volume":"308","author":"Della Corte","year":"2023","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"10.1016\/j.ejogrb.2025.113994_b0160","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3390\/pathogens13050381","article-title":"Post-Conization HPV Vaccination and Its Impact on Viral Status: A Retrospective Cohort Study in Troms and Finnmark, 2022","volume":"13","author":"Rykkelid","year":"2024","journal-title":"Pathogens"},{"issue":"8","key":"10.1016\/j.ejogrb.2025.113994_b0165","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1056\/NEJMsa0707052","article-title":"Health and economic implications of HPV vaccination in the United States","volume":"359","author":"Kim","year":"2008","journal-title":"N Engl J Med"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525002635?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525002635?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T07:15:47Z","timestamp":1747638947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211525002635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":33,"alternative-id":["S0301211525002635"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.113994","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Human papillomavirus 9-valent vaccine on viral clearance after surgical treatment: A single-center retrospective observational study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.113994","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113994"}}